Differential effects of route of T-2 toxin exposure on hepatic oxidative damage in mice.

abstract：:The chronic effect of p-nonylphenol on survival and reproduction for two generations of the freshwater cladoceran Daphnia galeata was examined by life table experiments. The effects on survival and reproduction were used as the intrinsic rate of natural increase, r, with the Euler-Lotka equation and were analyzed with...

journal_title：Environmental toxicology

authors： Tanaka Y,Nakanishi J

更新日期：2002-10-01 00:00:00

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:To study the effects and possible mechanisms of suspected endocrine disrupting compounds (EDCs), a wide variety of assays have been developed. In this work, we generated engineered Escherichia coli biosensor strains that incorporate the ligand-binding domains (LBDs) of the β-subtype estrogen receptors (ERβ) from Solea...

journal_title：Environmental toxicology

authors： Gierach I,Shapero K,Eyster TW,Wood DW

更新日期：2013-04-01 00:00:00

abstract：:The cytotoxic and genotoxic effects induced by alachlor and dichlorvos, two pesticides broadly used, were studied on RTG-2 fish cell line. As measure of cytotoxicity, neutral red assay was used to determine the cellular viability. Toxicity ranking based on IC(50) values found that alachlor was more cytotoxic than dich...

journal_title：Environmental toxicology

authors： Parra JM,Sánchez-Fortún S,Castaño A

更新日期：2012-03-01 00:00:00

abstract：:Microcystins (MCs), as the most dominant bloom-forming strains in eutrophic surface water, can induce hepatotoxicity by oxidative stress. Alpha-lipoic acid (α-LA) is a super antioxidant that can induce the synthesis of antioxidants, such as glutathione (GSH), by nuclear factor erythroid 2-related factor 2 (Nrf2). Howe...

journal_title：Environmental toxicology

authors： Gu L,Li S,Bai J,Zhang Q,Han Z

更新日期：2020-07-01 00:00:00

abstract：:Endotoxins exist anywhere including in water pools, dust, humidifier systems, and machining fluids. The major causal factor is endotoxins in many serious diseases, such as fever, sepsis, multi-organ failure, meningococcemia, and severe morbidities like neurologic disability, or hearing loss. Endotoxins are also called...

journal_title：Environmental toxicology

authors： Huang YC,Horng CT,Chen ST,Lee SS,Yang ML,Lee CY,Kuo WH,Yeh CH,Kuan YH

更新日期：2016-02-01 00:00:00

abstract：:Wood dusts, as a group, are categorized as known human carcinogens, but the risks of exposure to specific types of wood dusts and the carcinogenic chemicals they contain are not well studied. Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is linked to the carcinogenic action of specifi...

journal_title：Environmental toxicology

authors： Wilson MJ,Sabbioni G,Rando R,Miller CA 3rd

更新日期：2015-12-01 00:00:00

abstract：:Titanium dioxide nanoparticles (TiO2 NPs) have been used in environmental management, food, medicine, and industry. But TiO2 NPs have been demonstrated to cross the blood-brain barrier and store up in the brain organization, leading to glutamate-mediated neurotoxicity. However, the neurotoxicity in the brain is not we...

journal_title：Environmental toxicology

authors： Ze X,Su M,Zhao X,Jiang H,Hong J,Yu X,Liu D,Xu B,Sheng L,Zhou Q,Zhou J,Cui J,Li K,Wang L,Ze Y,Hong F

更新日期：2016-06-01 00:00:00

abstract：:The acute toxicity of the insecticide fenitrothion was measured using four freshwater algae (Chlorella saccharophila, Chlorella vulgaris, Scenedesmus acutus, and Scenedesmus subspicatus) and one cyanobacteria (Pseudanabaena galeata). Insecticide concentrations eliciting 50% growth reduction over 96 hr (EC50) ranged fr...

journal_title：Environmental toxicology

authors： Sabater C,Carrasco JM

更新日期：2001-01-01 00:00:00

abstract：:Colorectal cancer (CC) is an important human malignancy with high cancer related death worldwide. The chemotherapy using doxorubicin hydrochloride is one of the most common cancer therapeutic methods. However, drug resistance lowers the treatment efficacy in CC patients. The combination therapies seem to be more promi...

journal_title：Environmental toxicology

authors： Jadid MFS,Aghaei E,Taheri E,Seyyedsani N,Chavoshi R,Abbasi S,Khorrami A,Goleij P,Hajazimian S,Taefehshokr S,Isazadeh A,Shanehbandi D

更新日期：2021-01-28 00:00:00

abstract：:Malathion is one of the most commonly used insecticides. Recent findings have demonstrated that it induces oxidative stress in somatic cells, but there are not enough studies that have demonstrated this effect in germ cells. Malathion impairs porcine oocyte viability and maturation, but studies have not shown how oxid...

journal_title：Environmental toxicology

authors： Flores D,Souza V,Betancourt M,Teteltitla M,González-Márquez H,Casas E,Bonilla E,Ramírez-Noguera P,Gutiérrez-Ruíz MC,Ducolomb Y

更新日期：2017-06-01 00:00:00

abstract：:We measured the concentrations of monoamines in the brain of Japanese medaka, Oryzias latipes, exposed to tributyltin (TBT). Fish were exposed to 0, 1, 5, 25, or 125 microg g(-1) of TBT via the diet for 21 days. After the administration period, six males and six females in each treatment group were dissected and their...

journal_title：Environmental toxicology

authors： Nakayama K,Oshima Y,Tachibana T,Furuse M,Honjo T

更新日期：2007-02-01 00:00:00

abstract：:A high throughput culture methodology of unicellular eukaryote Tetrahymena pyriformis, strain GL were used for the determination of catecholamines toxicity and their metabolism. Catecholamines exhibited acute toxicity to Tetrahymena cells where dopamine and L-DOPA showed higher toxic potential of EC(10) (0.39 and 0.63...

journal_title：Environmental toxicology

authors： Ud-Daula A,Pfister G,Schramm KW

更新日期：2009-12-01 00:00:00

abstract：:Tributyltin (TBT), a well-known endocrine disruptor, is an omnipresent environmental pollutant and is explicitly used in many industrial applications. Previously we have shown its neurotoxic potential on cerebral cortex of male Wistar rats. As the effect of TBT on other brain regions is not known, we planned this stud...

journal_title：Environmental toxicology

authors： Mitra S,Siddiqui WA,Khandelwal S

更新日期：2015-12-01 00:00:00

abstract：:This work investigated the effects of mercury chloride (HgCl2 ) acute exposure on virgin, pregnant and lactating rats by determination of renal and hepatic morphological and ultrastructural parameters and the expression of oxidative stress and stress tolerance markers, due to kidney and liver are the organs that more ...

journal_title：Environmental toxicology

authors： Oliveira VA,Favero G,Stacchiotti A,Giugno L,Buffoli B,de Oliveira CS,Lavazza A,Albanese M,Rodella LF,Pereira ME,Rezzani R

更新日期：2017-05-01 00:00:00

abstract：:The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) has been widely used in agriculture and forestry since the 1940s. 2,4-D has been shown to produce a wide range of adverse effects-from embryotoxicity and teratogenicity to neurotoxicity-on animal and human health. The purpose of this study was to determine the possi...

journal_title：Environmental toxicology

authors： Pochettino AA,Bongiovanni B,Duffard RO,Evangelista de Duffard AM

更新日期：2013-01-01 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:There is increasing worldwide interest in developing of markers for tumor diagnosis and identification of individuals who are at high cancer risk. Cancer, like other diseases accompanied by metabolic disorders, causes characteristic effects on cell turnover rate, activity of modifying enzymes, and RNA/DNA modification...

journal_title：Environmental toxicology

authors： Seidel A,Seidel P,Manuwald O,Herbarth O

更新日期：2015-07-08 00:00:00

abstract：:The frequent occurrences of the toxic cyanobacterial (specifically Microcystis aeruginosa) bloom are becoming a global environmental issue. Lots of researches have been focused on the pure cyanobacterial toxins, but little on the natural cyanobacterial bloom. This study was undertaken to investigate the effect of the ...

journal_title：Environmental toxicology

authors： Huang P,Zheng YF,Xu LH

更新日期：2008-12-01 00:00:00

abstract：:Methyl tert-butyl ether (MTBE) is a gasoline oxygenate and antiknock additive substituting for lead alkyls currently in use worldwide. Previous studies have shown that MTBE at very high doses induces tumors in rodents. The aim of the present study was to examine directly the binding ability of MTBE onto DNA, demonstra...

journal_title：Environmental toxicology

authors： Du HF,Xu LH,Wang HF,Liu YF,Tang XY,Liu KX,Peng SX

更新日期：2005-08-01 00:00:00

abstract：:The bioaccumulation of the triazine herbicides terbutryn and terbuthylazine in rainbow trout was investigated at water temperatures of 4 degrees C, 10 degrees C, and 17 degrees C. The synergetic effect of water temperature and herbicide on fish liver detoxification metabolism was also studied by measuring liver ethoxy...

journal_title：Environmental toxicology

authors： Tarja N,Kirsti E,Marja L,Kari E

更新日期：2003-08-01 00:00:00

abstract：:Widespread occupational and environmental exposure to benzene is unavoidable and poses a public health threat. Studies of potential interventions to prevent or relieve benzene toxicity are, thus, essential. Research has shown l-carnitine (LC) has beneficial effects against various pathological processes and diseases. ...

journal_title：Environmental toxicology

authors： Sun R,Man Z,Ji J,Ji S,Xu K,Pu Y,Yu L,Zhang J,Yin L,Pu Y

更新日期：2020-10-01 00:00:00

abstract：:Dibutyltin (DBT) is the degradation products of TBT, which is generally considered higher toxicity than TBT in the immune system. In order to learn more about the mechanisms of immune-toxic of DBT, we exposed zebrafish (Danio rerio) to 0, 1, 10 and 100 ng/L DBT for 8 weeks. At the end of the experiment, we determined ...

journal_title：Environmental toxicology

authors： Zhang CN,Zhang JL,Huang Y,Ren HT,Guan SH,Zeng QH

更新日期：2018-01-01 00:00:00

abstract：:Microcystins are a family of potent hepatotoxins produced by freshwater cyanobacteria and can cause animal intoxications and human diseases. In this study, the effect of microcystin-LR (MC-LR) on the tissues of freshwater pearl mussel (Hyriopsis cumingii) was evaluated and differentially expressed genes in the hepatop...

journal_title：Environmental toxicology

authors： Yang Z,Wu H,Li Y

更新日期：2012-07-01 00:00:00

abstract：:Water bodies are routinely monitored for the presence of potentially toxic cyanobacteria; however, the methodology for confirming toxicity is currently complex and expensive. Here we describe the application of gene-based technology to rapidly identify cylindrospermopsin-producing cyanobacteria, specifically, Cylindro...

journal_title：Environmental toxicology

authors： Fergusson KM,Saint CP

更新日期：2003-04-01 00:00:00

abstract：:Environmental estrogens are major cause of endocrine disruption in vertebrates, including aquatic organisms. Teleosts are valuable and popular models for studying the effects of endocrine disrupting chemicals (EDCs) in the environment. In the present study, we investigated the changes caused by exposure to the synthet...

journal_title：Environmental toxicology

authors： Sridevi P,Chaitanya RK,Prathibha Y,Balakrishna SL,Dutta-Gupta A,Senthilkumaran B

更新日期：2015-04-01 00:00:00

abstract：:The correlation between the content of three microcystins (types LR, RR and YR) and the cell cycle of an axenic strain of Microcystis viridis, NIES-102, was investigated under conditions of high (16 mg L(-1)) and low (1.0 mg L(-1)) nitrate (NO(3)-N) concentrations. Each phase of the cell cycle was identified using a f...

journal_title：Environmental toxicology

authors： Kameyama K,Sugiura N,Inamori Y,Maekawa T

更新日期：2004-02-01 00:00:00

abstract：:Trichloroethylene (TCE) is ubiquitous in our living environment, and prenatal exposure to TCE is reported to cause congenital heart disease in humans. Although multiple studies have been performed using animal models, they have limited value in predicting effects on humans due to the unknown species-specific toxicolog...

journal_title：Environmental toxicology

authors： Jiang Y,Wang D,Zhang G,Wang G,Tong J,Chen T

更新日期：2016-11-01 00:00:00

abstract：:This study investigated lethal effects (i.e., survival) and sublethal effects (glutathione, GSH; lipid peroxidation, LPx; cholesterol, CHL; and acetylcholinesterase, AChE) of the antihyperlipidemic drug simvastatin on larval and adult grass shrimp (Palaemonetes pugio). The 96-h LC50 test for larvae resulted in an esti...

journal_title：Environmental toxicology

authors： Key PB,Hoguet J,Reed LA,Chung KW,Fulton MH

更新日期：2008-04-01 00:00:00

abstract：:The aim of this study was to determine whether repeated exposure to iron oxide nanoparticles (Fe2 O3 -NPs) could be toxic to mice testis. Fe2 O3 -NPs (25 and 50 mg/kg) were intraperitoneally administered into mice once a week for 4 weeks. Our study showed that Fe2 O3 -NPs have the ability to cross the blood-testis bar...

journal_title：Environmental toxicology

authors： Sundarraj K,Manickam V,Raghunath A,Periyasamy M,Viswanathan MP,Perumal E

更新日期：2017-02-01 00:00:00