Characterisation of cell-wall-derived polypeptide antigens from different species of Mycobacterium.

Abstract:

:Cell walls from different species of Mycobacterium were purified on a sucrose step gradient. The components derived from these preparations were characterised by sodium dodecyl sulphate-polyacrylamide gel electrophoresis, followed by staining or by Western blotting. Surface-exposed polypeptide molecules were also identified by biotinylation. Many protein and glycoprotein molecules were identified in the cell walls. Some of these molecules were immunogenic in man and experimental animals and showed wide variability from species to species. The data suggest that these molecules could be of significance in the diagnosis and pathophysiology of mycobacterial diseases.

journal_name

J Med Microbiol

authors

Babu S,Jain NK,Prasad G,Bhattacharya S,Bhattacharya A

doi

10.1099/00222615-32-4-263

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

263-9

issue

4

eissn

0022-2615

issn

1473-5644

journal_volume

32

pub_type

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