Algal lectins as promising biomolecules for biomedical research.

Abstract:

:Lectins are natural bioactive ubiquitous proteins or glycoproteins of non-immune response that bind reversibly to glycans of glycoproteins, glycolipids and polysaccharides possessing at least one non-catalytic domain causing agglutination. Some of them consist of several carbohydrate-binding domains which endow them with the properties of cell agglutination or precipitation of glycoconjugates. Lectins are rampant in nature from plants, animals and microorganisms. Among microorganisms, algae are the potent source of lectins with unique properties specifically from red algae. The demand of peculiar and neoteric biologically active substances has intensified the developments on isolation and biomedical applications of new algal lectins. Comprehensively, algal lectins are used in biomedical research for antiviral, antinociceptive, anti-inflammatory, anti-tumor activities, etc. and in pharmaceutics for the fabrication of cost-effective protein expression systems and nutraceutics. In this review, an attempt has been made to collate the information on various biomedical applications of algal lectins.

journal_name

Crit Rev Microbiol

authors

Singh RS,Thakur SR,Bansal P

doi

10.3109/1040841X.2013.798780

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

77-88

issue

1

eissn

1040-841X

issn

1549-7828

journal_volume

41

pub_type

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