Evidence on the impact of sustained exposure to air pollution on life expectancy from China's Huai River policy.

Abstract:

:This paper's findings suggest that an arbitrary Chinese policy that greatly increases total suspended particulates (TSPs) air pollution is causing the 500 million residents of Northern China to lose more than 2.5 billion life years of life expectancy. The quasi-experimental empirical approach is based on China's Huai River policy, which provided free winter heating via the provision of coal for boilers in cities north of the Huai River but denied heat to the south. Using a regression discontinuity design based on distance from the Huai River, we find that ambient concentrations of TSPs are about 184 μg/m(3) [95% confidence interval (CI): 61, 307] or 55% higher in the north. Further, the results indicate that life expectancies are about 5.5 y (95% CI: 0.8, 10.2) lower in the north owing to an increased incidence of cardiorespiratory mortality. More generally, the analysis suggests that long-term exposure to an additional 100 μg/m(3) of TSPs is associated with a reduction in life expectancy at birth of about 3.0 y (95% CI: 0.4, 5.6).

authors

Chen Y,Ebenstein A,Greenstone M,Li H

doi

10.1073/pnas.1300018110

subject

Has Abstract

pub_date

2013-08-06 00:00:00

pages

12936-41

issue

32

eissn

0027-8424

issn

1091-6490

pii

1300018110

journal_volume

110

pub_type

杂志文章
  • Lower bounds to eigenvalues of the Schrödinger equation by solution of a 90-y challenge.

    abstract::The Ritz upper bound to eigenvalues of Hermitian operators is essential for many applications in science. It is a staple of quantum chemistry and physics computations. The lower bound devised by Temple in 1928 [G. Temple, Proc. R. Soc. A Math. Phys. Eng. Sci. 119, 276-293 (1928)] is not, since it converges too slowly....

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.2007093117

    authors: Martinazzo R,Pollak E

    更新日期:2020-07-14 00:00:00

  • An endogenous retroviral long terminal repeat is the dominant promoter for human beta1,3-galactosyltransferase 5 in the colon.

    abstract::LTRs of endogenous retroviruses are known to affect expression of several human genes, typically as a relatively minor alternative promoter. Here, we report that an endogenous retrovirus LTR acts as one of at least two alternative promoters for the human beta1,3-galactosyltransferase 5 gene, involved in type 1 Lewis a...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.2134464100

    authors: Dunn CA,Medstrand P,Mager DL

    更新日期:2003-10-28 00:00:00

  • Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.

    abstract::Encoding ribonuclease H1 (RNase H1) degrades RNA hybridized to DNA, and its function is essential for mitochondrial DNA maintenance in the developing mouse. Here we define the role of RNase H1 in mitochondrial DNA replication. Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase H1 reveals ...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1503653112

    authors: Holmes JB,Akman G,Wood SR,Sakhuja K,Cerritelli SM,Moss C,Bowmaker MR,Jacobs HT,Crouch RJ,Holt IJ

    更新日期:2015-07-28 00:00:00

  • On the interactions of lipids and proteins in the red blood cell membrane.

    abstract::The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the prote...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.65.3.721

    authors: Glaser M,Simpkins H,Singer SJ,Sheetz M,Chan SI

    更新日期:1970-03-01 00:00:00

  • Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C).

    abstract::A gamma-trace variant protein is the major constituent of the amyloid fibrils in patients from Iceland with hereditary cerebral hemorrhage with amyloidosis. The protein consists of 110 residues and is similar to human urinary gamma-trace basic protein (or cystatin C) beginning at its 11th amino-terminal residue. It ha...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.83.9.2974

    authors: Ghiso J,Jensson O,Frangione B

    更新日期:1986-05-01 00:00:00

  • A distinct subset of plasmacytoid dendritic cells induces activation and differentiation of B and T lymphocytes.

    abstract::Plasmacytoid dendritic cells (pDCs) are known mainly for their secretion of type I IFN upon viral encounter. We describe a CD2hiCD5+CD81+ pDC subset, distinguished by prominent dendrites and a mature phenotype, in human blood, bone marrow, and tonsil, which can be generated from CD34+ progenitors. These CD2hiCD5+CD81+...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1610630114

    authors: Zhang H,Gregorio JD,Iwahori T,Zhang X,Choi O,Tolentino LL,Prestwood T,Carmi Y,Engleman EG

    更新日期:2017-02-21 00:00:00

  • Single liposome analysis of peptide translocation by the ABC transporter TAPL.

    abstract::ATP-binding cassette (ABC) transporters use ATP to drive solute transport across biological membranes. Members of this superfamily have crucial roles in cell physiology, and some of the transporters are linked to severe diseases. However, understanding of the transport mechanism, especially of human ABC exporters, is ...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1418100112

    authors: Zollmann T,Moiset G,Tumulka F,Tampé R,Poolman B,Abele R

    更新日期:2015-02-17 00:00:00

  • Phase geometries of two-dimensional excitable waves govern self-organized morphodynamics of amoeboid cells.

    abstract::In both randomly moving Dictyostelium and mammalian cells, phosphatidylinositol (3,4,5)-trisphosphate and F-actin are known to propagate as waves at the membrane and act to push out the protruding edge. To date, however, the relationship between the wave geometry and the patterns of amoeboid shape change remains elusi...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1218025110

    authors: Taniguchi D,Ishihara S,Oonuki T,Honda-Kitahara M,Kaneko K,Sawai S

    更新日期:2013-03-26 00:00:00

  • Multimonth controlled small molecule release from biodegradable thin films.

    abstract::Long-term, localized delivery of small molecules from a biodegradable thin film is challenging owing to their low molecular weight and poor charge density. Accomplishing highly extended controlled release can facilitate high therapeutic levels in specific regions of the body while significantly reducing the toxicity t...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1323829111

    authors: Hsu BB,Park MH,Hagerman SR,Hammond PT

    更新日期:2014-08-19 00:00:00

  • Insulin receptors in human circulating cells and fibroblasts.

    abstract::Human lymphocytes obtained from fasted adult subjects and cultured human tumor lymphocytes were investigated for specific insulin receptors. By use of monoiodoinsulin, specific insulin binding sites were demonstrated in peripheral human lymphocytes, cultured human lymphocytes, and in other types of human circulating c...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.69.3.747

    authors: Gavin JR 3rd,Roth J,Jen P,Freychet P

    更新日期:1972-03-01 00:00:00

  • Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineered Escherichia coli.

    abstract::Metabolic engineering seeks to reprogram microbial cells to efficiently and sustainably produce value-added compounds. Since chemical production can be at odds with the cell's natural objectives, strategies have been developed to balance conflicting goals. For example, dynamic regulation modulates gene expression to f...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1911144116

    authors: Dinh CV,Prather KLJ

    更新日期:2019-12-17 00:00:00

  • Genetic analysis of traditional and evolved Basmati and non-Basmati rice varieties by using fluorescence-based ISSR-PCR and SSR markers.

    abstract::The objective of the present study was to make use of efficient molecular marker systems to reveal genetic relationships in traditional and evolved Basmati (EB) and semidwarf non-Basmati (NB) rice varieties. A subset of three rice groups was analyzed by using 19 simple sequence repeat (SSR) loci and 12 inter-SSR-PCR p...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.042099099

    authors: Nagaraju J,Kathirvel M,Kumar RR,Siddiq EA,Hasnain SE

    更新日期:2002-04-30 00:00:00

  • Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor.

    abstract::Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two mediators synthesized by immune cells, specially under inflammatory and antigen stimulation conditions. Reports have shown that neuropeptides attenuate the deleterious consequences of septic shock both by down-re...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.012367999

    authors: Martinez C,Abad C,Delgado M,Arranz A,Juarranz MG,Rodriguez-Henche N,Brabet P,Leceta J,Gomariz RP

    更新日期:2002-01-22 00:00:00

  • Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.

    abstract::In vertebrate retinal photoreceptors, photoisomerization of opsin-bound visual chromophore 11-cis-retinal to all-trans-retinal triggers phototransduction events. Regeneration of the chromophore is a critical step in restoring photoreceptors to their dark-adapted state. This regeneration process, called the retinoid cy...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.0503318102

    authors: Golczak M,Kuksa V,Maeda T,Moise AR,Palczewski K

    更新日期:2005-06-07 00:00:00

  • Circadian rhythm of tyrosine hydroxylase induction by short-term cold stress: modulatory action of glucocorticoids in newborn and adult rats.

    abstract::The trans-synaptic induction of tyrosine hydroxylase [tyrosine 3-monooxygenase; EC 1.14.16.2, L-tyrosine, tetrahydropteridine: oxygen oxidoreductase (3-hydroxylating)] in adrenal medulla and sympathetic ganglia by short-term (1-2 hr) cold stress (4 degrees) exhibits a circadian rhythm which seems to be causally relate...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.72.4.1415

    authors: Otten U,Thoenen H

    更新日期:1975-04-01 00:00:00

  • Pathway-based personalized analysis of cancer.

    abstract::We introduce Pathifier, an algorithm that infers pathway deregulation scores for each tumor sample on the basis of expression data. This score is determined, in a context-specific manner, for every particular dataset and type of cancer that is being investigated. The algorithm transforms gene-level information into pa...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1219651110

    authors: Drier Y,Sheffer M,Domany E

    更新日期:2013-04-16 00:00:00

  • Enhanced recombination between lambda plac5 and F42lac: identification of cis- and trans-acting factors.

    abstract::Enhanced transductional recombination between specialized transducing phage lambda plac5 and plasmid F42lac depends on cis- and trans-acting factors. By constructing a series of recombinant molecules, the cis-acting site required for enhanced recombination has been identified as oriT, the origin of conjugational trans...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.81.23.7500

    authors: Seifert HS,Porter RD

    更新日期:1984-12-01 00:00:00

  • Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells.

    abstract::Androgen receptor (AR) protein expression and function are critical for survival and proliferation of androgen-sensitive (AS) prostate cancer cells. Besides its ability to function as a transcription factor, experimental observations suggest that AR becomes a licensing factor for DNA replication in AS prostate cancer ...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.0603057103

    authors: Litvinov IV,Vander Griend DJ,Antony L,Dalrymple S,De Marzo AM,Drake CG,Isaacs JT

    更新日期:2006-10-10 00:00:00

  • cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction.

    abstract::The major small nuclear ribonucleoproteins (snRNPs) U1, U2, U4/U6, and U5 share a set of common proteins denoted B/B', D1, D2, D3, E, F, and G which play an important part in the biogenesis of the snRNPs. In addition, there is a link between the common proteins and autoimmunity; the three D proteins, together with B/B...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.91.25.12317

    authors: Lehmeier T,Raker V,Hermann H,Lührmann R

    更新日期:1994-12-06 00:00:00

  • Distinct quaternary structures of the AAA+ Lon protease control substrate degradation.

    abstract::Lon is an ATPase associated with cellular activities (AAA+) protease that controls cell division in response to stress and also degrades misfolded and damaged proteins. Subunits of Lon are known to assemble into ring-shaped homohexamers that enclose an internal degradation chamber. Here, we demonstrate that hexamers o...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1307066110

    authors: Vieux EF,Wohlever ML,Chen JZ,Sauer RT,Baker TA

    更新日期:2013-05-28 00:00:00

  • Habituation as a neural algorithm for online odor discrimination.

    abstract::Habituation is a form of simple memory that suppresses neural activity in response to repeated, neutral stimuli. This process is critical in helping organisms guide attention toward the most salient and novel features in the environment. Here, we follow known circuit mechanisms in the fruit fly olfactory system to der...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1915252117

    authors: Shen Y,Dasgupta S,Navlakha S

    更新日期:2020-06-02 00:00:00

  • Regulated expression of endonuclease EcoRI in Saccharomyces cerevisiae: nuclear entry and biological consequences.

    abstract::In an investigation to determine how proteins are localized within the nucleus of a cell, we demonstrate that the restriction endonuclease EcoRI is able to enter and function within the nucleus of Saccharomyces cerevisiae when this prokaryotic protein is synthesized in vivo. The EcoRI endonuclease was produced in yeas...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.82.5.1354

    authors: Barnes G,Rine J

    更新日期:1985-03-01 00:00:00

  • Specific regulation of c-myc oncogene expression in a murine B-cell lymphoma.

    abstract::The c-myc oncogene has been implicated in a wide spectrum of B-cell neoplasias. In normal cells, the level of expression of the c-myc gene correlates with growth status. In the present study, we examined the effect of receptor-mediated inhibition of growth on c-myc expression in a B-cell lymphoma. The murine lymphoma ...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.81.17.5546

    authors: McCormack JE,Pepe VH,Kent RB,Dean M,Marshak-Rothstein A,Sonenshein GE

    更新日期:1984-09-01 00:00:00

  • Spectroscopic evidence for bulk-band inversion and three-dimensional massive Dirac fermions in ZrTe5.

    abstract::Three-dimensional topological insulators (3D TIs) represent states of quantum matters in which surface states are protected by time-reversal symmetry and an inversion occurs between bulk conduction and valence bands. However, the bulk-band inversion, which is intimately tied to the topologically nontrivial nature of 3...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1613110114

    authors: Chen ZG,Chen RY,Zhong RD,Schneeloch J,Zhang C,Huang Y,Qu F,Yu R,Li Q,Gu GD,Wang NL

    更新日期:2017-01-31 00:00:00

  • Protein Hal: partial deletion of a " " immunoglobulin gene(s) and apparent reinitiation at an internal AUG codon.

    abstract::Protein Hal is a human gamma4 heavy-chain disease protein whose molecular weight is reduced from 55,000 to 25,000 in 6 M guanidine due to the lack of disulfide bonds between heavy chains. Studies of aminoacid sequence indicate that it contains a gap of about 240 residues, starting 10 residues from the N-terminal end a...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.70.4.1073

    authors: Frangione B,Lee L,Haber E,Bloch KJ

    更新日期:1973-04-01 00:00:00

  • Immunochemical studies of fibroblasts from patients with methylmalonyl-CoA mutase apoenzyme deficiency: detection of a mutation interfering with mitochondrial import.

    abstract::Methylmalonyl-CoA mutase (2-methylmalonyl-CoA CoA-carbonylmutase, EC 5.4.99.2) is a mitochondrial enzyme whose deficiency in man leads to several biochemically and clinically heterogenous++ forms of methylmalonic acidemia. Intact fibroblasts from 21 patients with mutase apoenzyme deficiency have been pulse-labeled wit...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.84.5.1421

    authors: Fenton WA,Hack AM,Kraus JP,Rosenberg LE

    更新日期:1987-03-01 00:00:00

  • Obligatory role in GTP hydrolysis for the amide carbonyl oxygen of the Mg(2+)-coordinating Thr of regulatory GTPases.

    abstract::When G-protein alpha subunits binds GTP and Mg(2+), they transition from their inactive to their active conformation. This transition is accompanied by completion of the coordination shell of Mg(2+) with electrons from six oxygens: two water molecules, the ss and gamma phosphoryls of GTP, a helix-alpha1 Ser, and a swi...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.1004803107

    authors: Zurita A,Zhang Y,Pedersen L,Darden T,Birnbaumer L

    更新日期:2010-05-25 00:00:00

  • Ethological isolation among three species of the planitibia subgroup of Hawaiian Drosophila.

    abstract::Drosophila heteroneura and D. silvestris are sympatric species living on the island of Hawaii, while D. planitibia is allopatric on the nearby island of Maui. A pronounced ethological isolation is found between the sympatric species, and none between allopatric ones, except that D. planitibia females discriminate agai...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.71.3.901

    authors: Ahearn JN,Carson HL,Dobzhansky T,Kaneshiro KY

    更新日期:1974-03-01 00:00:00

  • Adaptation to famine: a family of stationary-phase genes revealed by microarray analysis.

    abstract::Bacterial adaptation to nutrient limitation and increased population densities is central to survival and virulence. Surprisingly, <3% of Escherichia coli genes are known to play roles specific to the stationary phase. There is evidence that the leucine-responsive regulatory protein (Lrp) may play an important role in...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.212510999

    authors: Tani TH,Khodursky A,Blumenthal RM,Brown PO,Matthews RG

    更新日期:2002-10-15 00:00:00

  • Excision in algebraic K-theory and Karoubi's conjecture.

    abstract::We prove that the property of excision in algebraic K-theory is for a Q-algebra A equivalent to the H-unitality of the latter. Our excision theorem, in particular, implies Karoubi's conjecture on the equality of algebraic and topological K-theory groups of stable C*-algebras. It also allows us to identify the algebrai...

    journal_title:Proceedings of the National Academy of Sciences of the United States of America

    pub_type: 杂志文章

    doi:10.1073/pnas.87.24.9582

    authors: Suslin AA,Wodzicki M

    更新日期:1990-12-15 00:00:00