Sildenafil for pediatric orbital lymphangioma.

abstract：Importance:Visual impairment and visual disorders often co-occur with other chronic conditions. Understanding patterns of multimorbidity is important for reducing health care use and improving health outcomes. Objective:To identify chronic condition patterns and their association with visual impairment and health care...

journal_title：JAMA ophthalmology

authors： Zheng DD,Christ SL,Lam BL,Feaster DJ,McCollister K,Lee DJ

更新日期：2020-04-01 00:00:00

abstract：Objective:To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. Design, Setting, and Participants:The Mycotic Ulcer Treatment Trial II (MUTT II), a multicenter, double-masked, placebo-controlled, randomized clinical trial, was conducted in India ...

journal_title：JAMA ophthalmology

authors： Prajna NV,Krishnan T,Rajaraman R,Patel S,Srinivasan M,Das M,Ray KJ,O'Brien KS,Oldenburg CE,McLeod SD,Zegans ME,Porco TC,Acharya NR,Lietman TM,Rose-Nussbaumer J,Mycotic Ulcer Treatment Trial II Group.

更新日期：2016-12-01 00:00:00

abstract：Importance:Most premature infants will not develop retinopathy of prematurity (ROP) of clinical relevance, yet screening evaluations often continue beyond hospital discharge, even for those infants without ROP. Objectives:To identify the characteristics of infants at low risk for ROP, for whom further postdischarge sc...

journal_title：JAMA ophthalmology

authors： Wade KC,Ying GS,Baumritter A,Gong A,Kemper AR,Quinn GE,e-ROP Cooperative Group.

更新日期：2019-02-01 00:00:00

abstract：IMPORTANCE:Further research is crucial to better understand the reason for falls in individuals with visual impairment (VI) and to develop appropriate fall prevention strategies. OBJECTIVE:To compare balance measures in individuals with normal vision, VI, and uncorrected refractive error (URE). DESIGN AND SETTING:Cro...

journal_title：JAMA ophthalmology

authors： Willis JR,Vitale SE,Agrawal Y,Ramulu PY

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:Acanthamoeba keratitis is a debilitating eye disease that requires effective topical drug therapy. Currently, there is no standard in vitro test to evaluate anti-Acanthamoeba drugs. OBJECTIVE:To develop a practical in vitro complete-kill assay to assess anti-Acanthamoeba drugs. DESIGN AND SETTING:Isolates ...

journal_title：JAMA ophthalmology

authors： Kowalski RP,Abdel Aziz S,Romanowski EG,Shanks RM,Nau AC,Raju LV

更新日期：2013-11-01 00:00:00

abstract：Importance:Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives:To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or without lamina cribrosa (LC) defects and to evaluate factors associated with the ra...

journal_title：JAMA ophthalmology

authors： Moghimi S,Zangwill LM,Manalastas PIC,Suh MH,Penteado RC,Hou H,Hasenstab K,Ghahari E,Bowd C,Weinreb RN

更新日期：2019-04-01 00:00:00

abstract：Importance:Although the association between suture colonization and postoperative infections remains hypothetical, measures to reduce perioperative suture colonization may minimize postoperative infections. The suture colonization rate in adjustable suture strabismus surgery is not well defined, and the effect of povid...

journal_title：JAMA ophthalmology

authors： Rossetto JD,Suwannaraj S,Cavuoto KM,Spierer O,Miller D,McKeown CA,Capo H

更新日期：2016-10-01 00:00:00

abstract：IMPORTANCE:We present a method to reintroduce ophthalmic training into the medical school curriculum. OBJECTIVES:To evaluate knowledge and skills acquired when participating in a service project, the Community Vision Project, and to develop a quantitative method for testing skills with the direct ophthalmoscope in pat...

journal_title：JAMA ophthalmology

authors： Byrd JM,Longmire MR,Syme NP,Murray-Krezan C,Rose L

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Although anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration (AMD) results in improved vision overall, loss of substantial vision can occur. Understanding the processes that lead to loss of vision may lead to preventive strategies. OBJECTIVE:To determine the inc...

journal_title：JAMA ophthalmology

authors： Ying GS,Kim BJ,Maguire MG,Huang J,Daniel E,Jaffe GJ,Grunwald JE,Blinder KJ,Flaxel CJ,Rahhal F,Regillo C,Martin DF,CATT Research Group.

更新日期：2014-08-01 00:00:00

abstract：IMPORTANCE:Adjunct treatments for conjunctival malignancies are needed when standard therapy provides limited benefits or fails. OBJECTIVE:To describe the results of patients with diffuse conjunctival neoplasms treated with radioactive phosphorus 32 (32P)-impregnated flexible film. DESIGN, SETTING, AND PARTICIPANTS:T...

journal_title：JAMA ophthalmology

authors： Marr BP,Abramson DH,Cohen GN,Williamson MJ,McCormick B,Barker CA

更新日期：2015-03-01 00:00:00

abstract：Importance:Preservation of peripheral visual field (VF) is considered an advantage for anti-vascular endothelial growth factor agents compared with panretinal photocoagulation (PRP) for treatment of proliferative diabetic retinopathy. Long-term data on VF are important when considering either treatment approach. Objec...

journal_title：JAMA ophthalmology

authors： Maguire MG,Liu D,Glassman AR,Jampol LM,Johnson CA,Baker CW,Bressler NM,Gardner TW,Pieramici D,Stockdale CR,Sun JK,DRCR Retina Network.

更新日期：2020-03-01 00:00:00

abstract：Importance:Optical coherence tomographic angiography (OCT-A) is able to visualize retinal microvasculature without the need for injection of fluorescein contrast dye. Nevertheless, it is only able to capture a limited view of macula and does not show leakage. Objectives:To evaluate the retinal microvasculature using O...

journal_title：JAMA ophthalmology

authors： Ting DSW,Tan GSW,Agrawal R,Yanagi Y,Sie NM,Wong CW,San Yeo IY,Lee SY,Cheung CMG,Wong TY

更新日期：2017-04-01 00:00:00

abstract：Importance:After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective:To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting,...

journal_title：JAMA ophthalmology

authors： Patel N,Pass A,Mason S,Gibson CR,Otto C

更新日期：2018-02-01 00:00:00

abstract：Importance:The comparative clinical effectiveness of ranibizumab, aflibercept, and bevacizumab for the management of macular edema due to central retinal vein occlusion (CRVO) is unclear. Objective:To determine whether intravitreal aflibercept or bevacizumab compared with ranibizumab results in a noninferior mean chan...

journal_title：JAMA ophthalmology

authors： Hykin P,Prevost AT,Vasconcelos JC,Murphy C,Kelly J,Ramu J,Hounsome B,Yang Y,Harding SP,Lotery A,Chakravarthy U,Sivaprasad S,LEAVO Study Group.

更新日期：2019-08-29 00:00:00

abstract：Importance:Uveitis has been associated with psoriatic arthritis, but to our knowledge, the relationship between uveitis and psoriasis is unsettled among researchers. Objective:To evaluate the risk of incident uveitis among people with psoriasis. Design, Setting, and Participants:This nationwide, retrospective cohort ...

journal_title：JAMA ophthalmology

authors： Chi CC,Tung TH,Wang J,Lin YS,Chen YF,Hsu TK,Wang SH

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of selective laser trabeculoplasty (SLT) for the treatment of primary open-angle glaucoma in an African-derived population in the developing world. METHODS:Sixty-one subjects from St. Lucia with medically treated primary open-angle glaucoma underwent a 30-day washout, followed by bil...

journal_title：JAMA ophthalmology

authors： Realini T

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To assess the benefit of increased follow-up and treatment with ranibizumab between months 24 and 36 in the Ranibizumab for Edema of the Macula in Diabetes (READ-2) Study. DESIGN:Prospective, interventional, multicenter follow-up of a randomized clinical trial. METHODS:Patients who agreed to participate bet...

journal_title：JAMA ophthalmology

authors： Do DV,Nguyen QD,Khwaja AA,Channa R,Sepah YJ,Sophie R,Hafiz G,Campochiaro PA,READ-2 Study Group.

更新日期：2013-02-01 00:00:00

abstract：Importance:The 2-year efficacy and safety of combination therapy of ranibizumab administered together with verteporfin photodynamic therapy (vPDT) compared with ranibizumab monotherapy in participants with polypoidal choroidal vasculopathy (PCV) are unclear. Objective:To compare treatment outcomes of ranibizumab, 0.5 ...

journal_title：JAMA ophthalmology

authors： Lim TH,Lai TYY,Takahashi K,Wong TY,Chen LJ,Ruamviboonsuk P,Tan CS,Lee WK,Cheung CMG,Ngah NF,Patalauskaite R,Margaron P,Koh A,EVEREST II Study Group.

更新日期：2020-09-01 00:00:00

abstract：IMPORTANCE:We define a Reading Accessibility Index for evaluating reading in individuals with normal and low vision. OBJECTIVE:To compare the Reading Accessibility Index with data from the Impact of Cataracts on Mobility (ICOM) study. DESIGN, SETTING, AND PARTICIPANTS:This investigation was a secondary data analysis ...

journal_title：JAMA ophthalmology

authors： Calabrèse A,Owsley C,McGwin G,Legge GE

更新日期：2016-04-01 00:00:00

abstract：Importance:To prevent blindness, repeated infant eye examinations are performed to detect severe retinopathy of prematurity (ROP), yet only a small fraction of those screened need treatment. Early individual risk stratification would improve screening timing and efficiency and potentially reduce the risk of blindness. ...

journal_title：JAMA ophthalmology

authors： Pivodic A,Hård AL,Löfqvist C,Smith LEH,Wu C,Bründer MC,Lagrèze WA,Stahl A,Holmström G,Albertsson-Wikland K,Johansson H,Nilsson S,Hellström A

更新日期：2019-11-07 00:00:00

abstract：Importance:Ocular manifestations and outcomes in children with confirmed coronavirus disease 2019 (COVID-19), relevant affecting factors, and differences in ocular disease between children and adults have yet to be fully understood. Objective:To investigate ocular manifestations and clinical characteristics of childre...

journal_title：JAMA ophthalmology

authors： Ma N,Li P,Wang X,Yu Y,Tan X,Chen P,Li S,Jiang F

更新日期：2020-10-01 00:00:00

abstract：Importance:Although low-income populations have more eye problems, whether they face greater difficulty obtaining eye care appointments is unknown. Objective:To compare rates of obtaining eye care appointments and appointment wait times for those with Medicaid vs those with private insurance. Design, Setting, and Par...

journal_title：JAMA ophthalmology

authors： Lee YH,Chen AX,Varadaraj V,Hong GH,Chen Y,Friedman DS,Stein JD,Kourgialis N,Ehrlich JR

更新日期：2018-06-01 00:00:00

abstract：Importance:The ocular surface is continuously exposed to the environment. Although studies have focused on associations between outdoor environmental conditions and dry eye, information on associations between the indoor environment and dry eye is lacking. Objective:To determine associations between the indoor environ...

journal_title：JAMA ophthalmology

authors： Huang A,Janecki J,Galor A,Rock S,Menendez D,Hackam AS,Jeng BH,Kumar N

更新日期：2020-08-01 00:00:00

abstract：IMPORTANCE:The Standard of Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) Study showed that intravitreal triamcinolone acetonide (IVTA) is effective at reducing macular edema and improving visual acuity in participants with retinal vein occlusion. Secondary analysis of the incidence, risk factors, and timing...

journal_title：JAMA ophthalmology

authors： Aref AA,Scott IU,Oden NL,Ip MS,Blodi BA,VanVeldhuisen PC,SCORE Study Investigator Group.

更新日期：2015-09-01 00:00:00

abstract：:Within 20 years of its discovery 100 years ago, vitamin A was recognized as critical to normal eyes, growth, and survival. Clinical interest subsequently contracted to its importance in preventing xerophthalmia, until this ophthalmologist stumbled, quite accidently, on its role in fighting life-threatening infections....

journal_title：JAMA ophthalmology

authors： Sommer A

更新日期：2014-01-01 00:00:00

abstract：Importance:The US Food and Drug Administration's medical device regulatory pathway was initially conceived with hardware devices in mind. The emerging market for ophthalmic digital devices necessitates an evolution of this paradigm. Objectives:To facilitate innovation in ophthalmic digital health with attention to saf...

journal_title：JAMA ophthalmology

authors： Bodnar ZM,Schuchard R,Myung D,Tarver ME,Blumenkranz MS,Afshari NA,Humayun MS,Morse C,Nischal K,Repka MX,Sprunger D,Trese M,Eydelman MB

更新日期：2019-06-06 00:00:00

abstract：IMPORTANCE:African American individuals are at high risk of diabetes mellitus and diabetic retinopathy but have suboptimal rates of dilated fundus examinations (DFEs). Early intervention is crucial for the prevention of diabetic retinopathy in this high-risk population. OBJECTIVE:To test the efficacy of behavioral act...

journal_title：JAMA ophthalmology

authors： Weiss DM,Casten RJ,Leiby BE,Hark LA,Murchison AP,Johnson D,Stratford S,Henderer J,Rovner BW,Haller JA

更新日期：2015-09-01 00:00:00

abstract：IMPORTANCE:Myopia (nearsightedness) has its onset in childhood and affects about one-third of adults in the United States. Along with its high prevalence, myopia is expensive to correct and is associated with ocular diseases that include glaucoma and retinal detachment. OBJECTIVE:To determine the best set of predictor...

journal_title：JAMA ophthalmology

authors： Zadnik K,Sinnott LT,Cotter SA,Jones-Jordan LA,Kleinstein RN,Manny RE,Twelker JD,Mutti DO,Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study Group.

更新日期：2015-06-01 00:00:00

abstract：IMPORTANCE:Medication persistence is an important factor for treatment effect in patients with glaucoma. Evaluating risk factors for refill discontinuation might be helpful for improving persistence and preventing blindness in patients with glaucoma. OBJECTIVES:To estimate the persistence rate with topical glaucoma me...

journal_title：JAMA ophthalmology

authors： Hwang DK,Liu CJ,Pu CY,Chou YJ,Chou P

更新日期：2014-12-01 00:00:00

abstract：Importance:The Argus II Retinal Prosthesis System is indicated for patients with vision loss due to severe to profound outer retinal degeneration, a group with few treatment options. Objectives:To collect postapproval safety and visual function data for the Argus II. Design, Setting, and Participants:Multicenter, pos...

journal_title：JAMA ophthalmology

authors： Schaffrath K,Schellhase H,Walter P,Augustin A,Chizzolini M,Kirchhof B,Grisanti S,Wiedemann P,Szurman P,Richard G,Greenberg RJ,Dorn JD,Parmeggiani F,Rizzo S

更新日期：2019-05-30 00:00:00