Circulating and tissue resident endothelial progenitor cells.

Abstract:

:Progenitor cells for the endothelial lineage have been widely investigated for more than a decade, but continue to be controversial since no unique identifying marker has yet been identified. This review will begin with a discussion of the basic tenets originally proposed for proof that a cell displays properties of an endothelial progenitor cell. We then provide an overview of the methods for putative endothelial progenitor cell derivation, expansion, and enumeration. This discussion includes consideration of cells that are present in the circulation as well as cells resident in the vascular endothelial intima. Finally, we provide some suggested changes in nomenclature that would greatly clarify and demystify the cellular elements involved in vascular repair.

journal_name

J Cell Physiol

authors

Basile DP,Yoder MC

doi

10.1002/jcp.24423

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

10-6

issue

1

eissn

0021-9541

issn

1097-4652

journal_volume

229

pub_type

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