Abstract:
BACKGROUND:Lung transplant recipients are at great risk for developing various infectious complications. These infections portend a significant morbidity and mortality throughout their lifetime following transplantation. At times, cutaneous manifestations are the only clues to systemic infection. CASE REPORT:A 62 year-old man with a history of idiopathic pulmonary fibrosis presented 6 months after receiving bilateral sequential cadaveric lung transplantation for anorexia, early satiety, weight loss, exertional dsypnea, arthralgia, and depression. On exam, two rapidly growing non-painful 1.5-3 centimeter erythematous nodules with purulent draining on the anterior chest wall were noted. On Hospital Day 7, the patent was found to be un-responsive, hypotensive, and febrile. Brain imaging revealed diffuse thick nodular enhancement of leptomeningeal surface and multiple areas of hypodenisty associated with mass effect in the bilateral vermis and cerebellar hemispheres with effacement of the fourth ventricle. CSF PCR analysis showed Acanthamoeba sp. confirmed by the Center for Disease Control. Despite multi-modal therapy, his clinical course deteriorated and resulted in brain death. CONCLUSION:Acanthamoeba infection is extremely rare in thoracic organ recipients. We report the fifth case of progressive disseminated acanthamoebiasis in a lung transplant recipient.
journal_name
Ann Transplantjournal_title
Annals of transplantationauthors
Afshar K,Boydking A,Ganesh S,Herrington C,McFadden PMdoi
10.12659/AOT.883846subject
Has Abstractpub_date
2013-03-14 00:00:00pages
108-11eissn
1425-9524issn
2329-0358pii
883846journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Transarterial chemoembolization (TACE) induces ischemic tumor necrosis, which is intensified by regional chemotherapy. By reducing the active tumor tissue, it can be assumed that patients on the waiting list for liver transplantation may benefit from this locoregional treatment. The aim of this study was to ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.896778
更新日期:2015-12-29 00:00:00
abstract::Transplantation medicine, like no other medical specialty, is connected with a wide range of very difficult ethical issues. Among those are: availability of the treatment, consent for cadaveric donation, allocation of available organs, new categories of living unrelated donors and economic aspects of this method of tr...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The results of pancreas transplantation depend in a large degree on appropriate pancreas allograft donor selection. Several risk factors of early surgical complications or pancreas allograft loss following transplantation have been identified, but the final decision on pancreas harvesting for transplantation...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.894464
更新日期:2015-11-03 00:00:00
abstract:BACKGROUND:Xenotransplantation from pig to humans may be associated with the risk of transmission of porcine endogenous retroviruses (PERVs) that are present in the genome of all pigs and that infect human cells in vitro. However, it remains unclear whether PERVs infect transplant recipients in vivo and, if so, whether...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Intraoperative circulatory risk factors are associated with unfavorable outcomes after living donor liver transplantation (LDLT). We investigated whether the preoperative neutrophil-to-lymphocyte ratio (NLR) can predict intraoperative circulatory risks. MATERIAL AND METHODS:The perioperative data of 276 pat...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.894048
更新日期:2015-07-21 00:00:00
abstract::Year by year the actual number of transplanted organs has been growing in Poland. In the event of the Województwo Zachodniopomorskie (Western Pomeranian Province) the primary activities were focused on informing medical personnel at hospital departments about approaching donors through trainings for such medical perso...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::For each individual, there is a limit to the capacity to perform exercise. The limitation, however, depends on the nature of the task and is also influenced by a number of other factors. Muscle strength is determined largely by muscle mass, specifically muscle cross-sectional area, but is also influenced by neural dri...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract::BACKGROUND The incidence of surgical complications after kidney transplantation ranges from 10-25%. The purpose of this study was to evaluate if the application of fibrin glue as a preventive agent reduces surgical morbidity after a living-related-donor kidney transplantation. MATERIAL AND METHODS A controlled clinica...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.899821
更新日期:2016-09-20 00:00:00
abstract::Between August 2006 and August 2009, 34 ethnic Mongolians were the recipients of a kidney transplant at the Central Clinical Hospital in Ulaanbaatar, Mongolia. In 31 of the operations the donor was either a sibling or parent. In 4 recipients the donors were 2 recently deceased accident victims following controlled car...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.882647
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:In spite of progress in biotechnology, isolation of porcine pancreatic islets remains a difficult task with unpredictable results. One reason could be the lack of knowledge as to the expression of extracellular matrix proteins in porcine exocrine and endocrine tissues, particularly in "islet capsules". Such ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Transplantation of liver has been remarkably effective in the treatment of liver failure and liver-based inherited metabolic diseases and has revolutionized the care of patients with end-stage liver disease. Unfortunately demand for transplantable livers is progressively outpacing the supply of donated cadaver organs,...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Autologous peripheral blood stem cell transplantation (PBSCT) is commonly used in the treatment of lymphoma patients. G-CSF is widely used to boost white blood cell recovery. However, there are no clear data indicating which strategy of using G-CSF provides the most benefit. The aim of our study was to compa...
journal_title:Annals of transplantation
pub_type: 杂志文章,多中心研究
doi:10.12659/AOT.883965
更新日期:2013-07-02 00:00:00
abstract:BACKGROUND:Graft-versus-host disease (GvHD) is the most important complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) responsible for increased mortality. Recent studies have discussed the use of oral GvHD screening tests in the diagnosis of systemic GvHD. This is the first study of the si...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.883462
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to characterize patient antibodies before and after cadaver and/or living-donor kidney transplantation and to correlate these data with the clinical course after transplantation. METHODS:Sera from 69 cadaver, 9 living-related and 2 patients waiting for living-donor kidney transplant...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::BACKGROUND Correction of hypovitaminosis D is simple, but it is unclear whether it is associated with an accelerated decline of renal allograft function in pediatric renal transplantation patients. This retrospective single center cohort study aimed at analyzing the effect of vitamin D and covariates on the slope of 1...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2018-04-17 00:00:00
abstract:BACKGROUND:Animal models to investigate pathophysiology and xenotransplantation require complex techniques and significant animal utilization. The aim of the study was to develop a reliable ex-vivo technique to test xenotransplant interventions. MATERIAL/METHODS:Miniature Swine being utilized for a nonsurvival study a...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::The aim of the report is to present successful surgical treatment of aneurysm of common iliac artery (CIA) and internal iliac artery (IIA) in a kidney transplant patient. The aneurysm of CIA and IIA, causing arterial hypertension, was diagnosed and treated surgically in a 47-year-old male patient, who had received a c...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::BACKGROUND Percutaneous liver biopsy is an established diagnostic procedure for the assessment of liver pathologies. Limited data are available on the clinical impact of liver biopsies in liver transplant recipients. MATERIAL AND METHODS Liver transplant recipients undergoing liver biopsy between 2000 and 2013 were an...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.901487
更新日期:2017-02-24 00:00:00
abstract::BACKGROUND The aim of this study was to investigate the clinical features and treatment strategies of transplant renal artery stenosis (TRAS) with kidneys from donation after cardiac death (DCD). MATERIAL AND METHODS We collected the clinical data of donors and recipients of single-center DCD-induced TRAS from January...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.918076
更新日期:2020-02-04 00:00:00
abstract::Stem cell research seems now to reach important progress in biomedicine, giving promising perspective for clinical implementation. The review of stem cell research is presented including origin, content in various organs, harvesting, preservation and storage. Some examples of results achieved in stem cell research inc...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:To investigate whether the retroperitoneal or transperitoneal approach is preferable for right-sided laparoscopic donor nephrectomy (R-LDN). MATERIAL/METHODS:We retrospectively compared the donor and recipient outcomes of R-LDNs performed with a standard transperitoneal approach (n=21) or a semi-open retrop...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract::Aim of this monocentric study is to compare the outcome of 101 renal transplants performed in patients older than 55 years with single kidney retrieved from donors older than 50 years, with 263 transplants performed in patients younger than 55 years transplanted with young kidneys. Delayed graft function (DGF) had sim...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Successful kidney transplantation (KT) improves significantly the quality of life as compared with hemodialysis. Vocational rehabilitation and professional activity are the vital part of general rehabilitation and play an important role in determining the quality of life. The aim of this study was to evaluate the degr...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Antibody-mediated rejection (AMR), associated with the presence of C4d deposits, is well-defined in kidney transplantation but much less documented in liver transplantation (LTx). The aim of our study was to retrospectively analyze a group of pediatric liver transplant recipients who experienced episodes of ...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.889921
更新日期:2014-03-04 00:00:00
abstract:UNLABELLED:Glutathione S-Tranferases (GST) are the enzymes which are strictly specific for epithelial cells of the proximal and distal tubules in the kidney. These enzymes are detected in the urine when some tubular damage process is found. In healthy people urine GST is hardly detected. The goal of this study was to e...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::BACKGROUND Long-term real-world data are relatively sparse regarding recurrence of chronic hepatitis B virus (HBV) infection after liver transplantation using hepatitis B immunoglobulin (HBIg) and nucleos(t)ide analogue (NUC) prophylaxis. MATERIAL AND METHODS Data from 371 adults transplanted for HBV-related disease a...
journal_title:Annals of transplantation
pub_type: 杂志文章,多中心研究
doi:10.12659/AOT.910176
更新日期:2018-11-13 00:00:00
abstract::Ano-genital neoplasia is about 20 x more common in renal transplant patients than the general population. Neoplasms in the immunosuppressed are more morbid and mortal because: patients are younger; tumors are more undifferentiated; they have more and larger foci; more sites are involved; neoplasms tend to persist, rec...
journal_title:Annals of transplantation
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:The goal of this study was to examine the impact of various immunosuppressive regimens on an early NK cell recovery following haematopoietic cell transplantation (alloHCT). METHODS:The number of peripheral blood NK cells was analysed with the use of flow cytometry on day +30 (+/-2) after alloHCT from an HLA...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::BACKGROUND Solid organ transplantations lead to improvements in patient survival and patient quality of life, as well as health care system economic benefits. However, over time, health problems can accumulate post-transplantation. Therefore, we hypothesized that in the late post-transplantation period, the costs of p...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/AOT.914661
更新日期:2019-05-07 00:00:00
abstract::BACKGROUND Dual kidney transplantation (DKT) of expanded-criteria donors is a cost-intensive procedure that aims to increase the pool of available deceased organ donors and has demonstrated equivalent outcomes to expanded-criteria single kidney transplantation (eSKT). The objective of this study was to develop an allo...
journal_title:Annals of transplantation
pub_type: 杂志文章
doi:10.12659/aot.898328
更新日期:2016-09-08 00:00:00