Moraxella catarrhalis uses a twin-arginine translocation system to secrete the β-lactamase BRO-2.

abstract：BACKGROUND:Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in treatment failures of bacterial infections. While this phenomenon has posed a great threat in public health, mechanisms underlying their formation in Staphylococcus aureus remain largely unknown. Increasing evi...

journal_title：BMC microbiology

authors： Sahukhal GS,Pandey S,Elasri MO

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Accumulation of gyrase cleavage complex in Escherichia coli from the action of quinolone antibiotics induces an oxidative damage cell death pathway. The oxidative cell death pathway has also been shown to be involved in the lethality following accumulation of cleavage complex formed by bacterial topoisomeras...

journal_title：BMC microbiology

authors： Liu IF,Aedo S,Tse-Dinh YC

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Affecting the core functional microbiome, peculiar high level taxonomic unbalances of the human intestinal microbiota have been recently associated with specific diseases, such as obesity, inflammatory bowel diseases, and intestinal inflammation. RESULTS:In order to specifically monitor microbiota unbalance...

journal_title：BMC microbiology

authors： Candela M,Consolandi C,Severgnini M,Biagi E,Castiglioni B,Vitali B,De Bellis G,Brigidi P

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:The 19 kDa lipoprotein of Mycobacterium tuberculosis (MTB) is an important target of the innate immune response. To investigate the effect of post-translation modification of this protein on innate recognition in the context of the whole bacillus, we derived a recombinant M. tuberculosis H37Rv that lacked th...

journal_title：BMC microbiology

authors： Wilkinson KA,Newton SM,Stewart GR,Martineau AR,Patel J,Sullivan SM,Herrmann JL,Neyrolles O,Young DB,Wilkinson RJ

更新日期：2009-05-14 00:00:00

abstract：BACKGROUND:The opportunistic pathogen, Pseudomonas aeruginosa is well known for its environmental and metabolic versatility, yet many of the functions of its gene-products remain to be fully elucidated. This study's objective was to illuminate the potential functions of under-described gene-products during the medicall...

journal_title：BMC microbiology

authors： Wright BW,Kamath KS,Krisp C,Molloy MP

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The influence of the membrane-bound AAA+ protease FtsH on membrane and cytoplasmic proteins of Corynebacterium glutamicum was investigated in this study. For the analysis of the membrane fraction, anion exchange chromatography was combined with SDS-PAGE, while the cytoplasmic protein fraction was studied by ...

journal_title：BMC microbiology

authors： Lüdke A,Krämer R,Burkovski A,Schluesener D,Poetsch A

更新日期：2007-01-25 00:00:00

abstract：BACKGROUND:Most of the studies evaluating the secular trends of blood isolates come from tertiary hospitals in urban areas. We sought to study the trends of the antimicrobial resistance of blood isolates in patients from a rural population hospitalized in a tertiary hospital in a small city in Greece. METHODS:We retro...

journal_title：BMC microbiology

authors： Falagas ME,Bakossi A,Pappas VD,Holevas PV,Bouras A,Stamata E

更新日期：2006-05-02 00:00:00

abstract：BACKGROUND:Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation. In this study, we used a high-throughput pyrosequencing approach to sequence the transcriptome of S. meliloti, and search for new bacterial genes missed in the previous ...

journal_title：BMC microbiology

authors： Mao C,Evans C,Jensen RV,Sobral BW

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:The increase in resistance to antibiotics among disease-causing bacteria necessitates the development of alternative antimicrobial approaches such as the use of light-activated antimicrobial agents (LAAAs). Light of an appropriate wavelength activates the LAAA to produce cytotoxic species which can then caus...

journal_title：BMC microbiology

authors： Omar GS,Wilson M,Nair SP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Xanthophyllomyces dendrorhous is a basidiomycetous yeast that synthesizes astaxanthin, a carotenoid with great biotechnological impact. The ergosterol and carotenoid synthetic pathways derive from the mevalonate pathway and involve cytochrome P450 enzymes. Among these enzymes, the CYP51 family, which is invo...

journal_title：BMC microbiology

authors： Leiva K,Werner N,Sepúlveda D,Barahona S,Baeza M,Cifuentes V,Alcaíno J

更新日期：2015-04-25 00:00:00

abstract：BACKGROUND:Francisella tularensis is a fastidious, Gram-negative coccobacillus and is the causative agent of tularemia. To assess viability yet overcome lengthy incubation periods, a culture-based PCR method was used to detect early growth of the lowest possible number of F. tularensis cells. This method utilized a pre...

journal_title：BMC microbiology

authors： Buse HY,Morris BJ,Rice EW

更新日期：2020-03-25 00:00:00

abstract：BACKGROUND:Probiotics have been reported to reduce total cholesterol levels in vitro, but more evidence is needed to determine the clinical relevance of this activity. Chinese traditional fermented pickles are a good source of lactic acid bacteria. Therefore, pickle samples were collected for screening lactic acid bact...

journal_title：BMC microbiology

authors： Zheng ZY,Cao FW,Wang WJ,Yu J,Chen C,Chen B,Liu JX,Firrman J,Renye J,Ren DX

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Epidemiology of celiac disease (CD) is increasing. CD mainly presents in early childhood with small intestinal villous atrophy and signs of malabsorption. Compared to healthy individuals, CD patients seemed to be characterized by higher numbers of Gram-negative bacteria and lower numbers Gram-positive bacter...

journal_title：BMC microbiology

authors： Di Cagno R,De Angelis M,De Pasquale I,Ndagijimana M,Vernocchi P,Ricciuti P,Gagliardi F,Laghi L,Crecchio C,Guerzoni ME,Gobbetti M,Francavilla R

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:Bacteriocins are antimicrobial proteins and peptides ribosomally synthesized by some bacteria which can effect both intraspecies and interspecies killing. RESULTS:Moraxella catarrhalis strain E22 containing plasmid pLQ510 was shown to inhibit the growth of M. catarrhalis strain O35E. Two genes (mcbA and mcb...

journal_title：BMC microbiology

authors： Attia AS,Sedillo JL,Hoopman TC,Liu W,Liu L,Brautigam CA,Hansen EJ

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:Biofilm formation by Candida albicans has shown to be highly variable and is directly associated with pathogenicity and poor clinical outcomes in patients at risk. The aim of this study was to test the hypotheses that the extracellular DNA release by C. albicans is strain dependent and is associated with bio...

journal_title：BMC microbiology

authors： Rajendran R,Sherry L,Lappin DF,Nile CJ,Smith K,Williams C,Munro CA,Ramage G

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:During the last two decades research on animal filarial parasites, especially Onchocerca ochengi, infecting cattle in savanna areas of Africa revealed that O. ochengi as an animal model has biological features that are similar to those of O. volvulus, the aetiological agent of human onchocerciasis. There is,...

journal_title：BMC microbiology

authors： Ngwasiri NN,Brattig NW,Ndjonka D,Liebau E,Paguem A,Leusder D,Kingsley MT,Eisenbarth A,Renz A,Daniel AM

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Non-structural protein 1 (NS1) is a multifunctional protein and a crucial regulatory factor in the replication and pathogenesis of avian influenza virus (AIV). Studies have shown that NS1 can interact with a variety of host proteins to modulate the viral life cycle. We previously generated a monoclonal antib...

journal_title：BMC microbiology

authors： Ma Y,Sun J,Gu L,Bao H,Zhao Y,Shi L,Yao W,Tian G,Wang X,Chen H

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:DING proteins constitute a conserved and broadly distributed set of proteins found in bacteria, fungi, plants and animals (including humans). Characterization of DING proteins from animal and plant tissues indicated ligand-binding ability suggesting a role for DING proteins in cell signaling and biomineraliz...

journal_title：BMC microbiology

authors： Zhang XX,Scott K,Meffin R,Rainey PB

更新日期：2007-12-18 00:00:00

abstract：BACKGROUND:A common assumption of microorganisms is that laboratory stocks will remain genetically and phenotypically constant over time, and across laboratories. It is becoming increasingly clear, however, that mutations can ruin strain integrity and drive the divergence or "domestication" of stocks. Since its discove...

journal_title：BMC microbiology

authors： Carroll SM,Xue KS,Marx CJ

更新日期：2014-01-02 00:00:00

abstract：BACKGROUND:Compared with many protists, Giardia lamblia has a simple life cycle alternating between cyst and trophozoite. Most research on the molecular biology of Giardia parasites has focused on trophozoites and the processes of excystation and encystation, whereas cysts have attracted less interest. The striking mor...

journal_title：BMC microbiology

authors： Faghiri Z,Widmer G

更新日期：2011-05-04 00:00:00

abstract：BACKGROUND:Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is generally employed for the rapid identification of fungal isolates. However, the results are based on s...

journal_title：BMC microbiology

authors： Nakamura S,Sato H,Tanaka R,Kusuya Y,Takahashi H,Yaguchi T

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:The ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. Mycobacterium fortuitum is a bacteria that contains genes involved in the detoxification of the oxygen reactive species such as those produced by the host during t...

journal_title：BMC microbiology

authors： Núñez MC,Menéndez MC,Rebollo MJ,García MJ

更新日期：2008-06-19 00:00:00

abstract：BACKGROUND:Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood. We sought to determine the effect of environmental variability on growth in vitro and to assess variability between strains. We evaluated the effect of temperat...

journal_title：BMC microbiology

authors： Tóthpál A,Desobry K,Joshi SS,Wyllie AL,Weinberger DM

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:The emergence of antibiotic resistant pathogenic bacteria has reduced our ability to combat infectious diseases. At the same time the numbers of new antibiotics reaching the market have decreased. This situation has created an urgent need to discover novel antibiotic scaffolds. Recently, the application of p...

journal_title：BMC microbiology

authors： Hoerr V,Duggan GE,Zbytnuik L,Poon KK,Große C,Neugebauer U,Methling K,Löffler B,Vogel HJ

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:It has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting protocols. The purpose of this study was to assess the effects of different daily fasting hours on shaping the gut microbiota in mice. Healthy C57BL/6 J ...

journal_title：BMC microbiology

authors： Li L,Su Y,Li F,Wang Y,Ma Z,Li Z,Su J

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:The kinetoplast DNA (kDNA) of trypanosomatids consists of an unusual arrangement of circular molecules catenated into a single network. The diameter of the isolated kDNA network is similar to that of the entire cell. However, within the kinetoplast matrix, the kDNA is highly condensed. Studies in Crithidia f...

journal_title：BMC microbiology

authors： Cavalcanti DP,Shimada MK,Probst CM,Souto-Padrón TC,de Souza W,Goldenberg S,Fragoso SP,Motta MC

更新日期：2009-06-04 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is produced as part of the host immune response to bacterial infections, including urinary tract infections. The enzyme flavohemoglobin, coded by the hmp gene, is involved in protecting bacterial cells from the toxic effects of NO and represents a potentially interesting target for developm...

journal_title：BMC microbiology

authors： Bang CS,Kinnunen A,Karlsson M,Önnberg A,Söderquist B,Persson K

更新日期：2014-03-14 00:00:00

abstract：BACKGROUND:Acetic acid has been used to clean and disinfect surfaces in the household for many decades. The antimicrobial efficacy of cleaning procedures can be considered particularly important for young, old, pregnant, immunocompromised people, but may also concern other groups, particularly with regards to the COVID...

journal_title：BMC microbiology

authors： Zinn MK,Bockmühl D

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Changes in aboveground plant species diversity as well as variations of environmental conditions such as exposure of ecosystems to elevated concentrations of atmospheric carbon dioxide may lead to changes in metabolic activity, composition and diversity of belowground microbial communities, both bacterial an...

journal_title：BMC microbiology

authors： Grüter D,Schmid B,Brandl H

更新日期：2006-07-27 00:00:00