Abstract:
OBJECTIVE:To assess the value of serum mesothelin concentration for diagnosis of ovarian cancer and for monitoring the therapeutic effect of surgical treatment. MATERIALS AND METHODS:The study consisted of 42 patients with ovarian cancer undergoing surgery, 48 with benign ovarian tumors, and 49 healthy controls. Blood was drawn pre-operatively and one month post-operatively to test serum mesothelin levels. RESULTS:Mesothelin values were higher in the ovarian cancer group compared to controls and higher preoperatively vs post-operatively in the ovarian cancer group. For the diagnosis of ovarian cancer, the positive predictive value of serum mesothelin was 80.5%, the negative predictive value was 81.6%, sensitivity was 78.6%, and specificity was 83.3%. CONCLUSION:Serum mesothelin is increased in ovarian cancer, has high-specificity, and can be used in the pre-operative diagnostic evaluation for ovarian cancer.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Qiao N,Li Hsubject
Has Abstractpub_date
2013-01-01 00:00:00pages
163-5issue
2eissn
0392-2936issn
2709-0086journal_volume
34pub_type
杂志文章abstract::A case of primary retroperitoneal mucinous cystadenoma in a 67-year-old woman is reported, associated with a microinvasive vulvar carcinoma. The cystic tumor measured about 30x20x10 cm and the ovaries appeared normal. The histogenesis of this rare tumor is uncertain: most Authors suggest that it develops through mucin...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::We are currently faced with a progressive delay in the age at which women conceive for the first time. This raises the possibility of the appearance of gynecologic disorders that may affect fertility, including neoplasms of the ovary. Fertility-sparing surgery is defined as the preservation of ovarian tissue in one or...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:Three cases of pelvic actinomycosis initially diagnosed as pelvic malignancy and treated surgically are reported. CASES:The first case was a 38-year-old multiparous woman who was referred to our clinic because of bilateral ovarian solid masses. With the impression of ovarian carcinoma, a laparotomy was perfo...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Small cell neuroendocrine carcinoma of the breast is a rare tumor with fewer than 30 cases reported in the literature. The reported age of incidence of mammary small cell carcinoma is similar to that of breast carcinoma of the usual types. CASE:The clinicopathologic findings of a primary mammary small cell ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract::Several data indicate that the activation of oncogenes and growth factors as well as inactivation of the tumor suppressor genes are implicated in the development of human neoplasms, including sarcomas. In the present study we described a case of the extremely rare, but highly malignant neoplasm of the female genital t...
journal_title:European journal of gynaecological oncology
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doi:
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To compare physician and nurse practitioner accuracy in recognizing cervical dysplasia during colposcopy. MATERIALS AND METHODS:A retrospective review was performed of cervical excisional biopsies from 2007 to 2009 performed by gynecologists and nurse practitioners in the same patient population. Cervical cone...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Endometrial stromal sarcoma (ESS) is a rare malignancy of the uterus. Most cases are incidentally diagnosed on histological examination of hysterectomy specimens. Evidence on the management is accrued mainly from retrospective studies. This study aims to review the clinical experience of a district hospital in ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract::In order to determine the clinical significance of numerical aberrations on chromosome 17 in uterine cervical and endometrial neoplasias, we investigated 140 cell specimens obtained from the uterine cervix and endometrium using the fluorescence in situ hybridization (FISH) method. These specimens consisted of ten norm...
journal_title:European journal of gynaecological oncology
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doi:
更新日期:2000-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::Endodermal sinus tumor (EST) of the ovary is a germ cell tumor that is now recognized more frequently than in the past. Since problems concerning natural history, prognosis and therapy of these neoplasms are not entirely resolved, it should be underlined the need to report new cases. The authors describe four cases of...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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doi:
更新日期:2002-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
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doi:
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Surgical staging in early endometrial cancer is not universally done and lymphadenectomy in early-stage disease is controversial. Aim of the present study was to evaluate surgical staging in patients with endometrioid histology, FIGO Stage IA endometrial cancer. MATERIALS AND METHODS:Eighty-seven patients with...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
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doi:
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