Abstract:
:Bronchiolitis is an inflammatory and potentially fibrosing condition affecting mainly the intralobular conducting and transitional small airways. Secondary bronchiolitis participates in disease process of the airways and/or the surrounding lobular structures in the setting of several already defined clinical entities, mostly of known etiology, and occurs commonly. Primary or idiopathic bronchiolitis dominates and characterizes distinct clinical entities, all of unknown etiology, and occurs rarely. Secondary bronchiolitis regards infections, hypersensitivity disorders, the whole spectrum of smoking-related disorders, toxic fumes and gas inhalation, chronic aspiration, particle inhalation, drug-induced bronchiolar toxicities, sarcoidosis and neoplasms. Idiopathic or primary bronchiolitis defines clinicopathologic entities sufficiently different to be designated as separate disease entities and include cryptogenic constrictive bronchiolitis, diffuse panbronchiolitis, diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, neuroendocrine hyperplasia in infants, bronchiolitis obliterans syndrome in lung and allogeneic hematopoietic cell transplantation, connective tissue disorders, inflammatory bowel disease and bronchiolitis obliterans organizing pneumonia. Most of the above are pathological descriptions used as clinical diagnosis. Acute bronchiolitis, though potentially life threatening, usually regresses. Any etiology chronic bronchiolitis contributes to morbidity and/or mortality if it persists and/or progresses to diffuse airway narrowing and distortion or complete obliteration. Bronchiolitis in specific settings leads to bronchiolectasis, resulting in bronchiectasis.
journal_name
Expert Rev Respir Medjournal_title
Expert review of respiratory medicineauthors
Papiris SA,Malagari K,Manali ED,Kolilekas L,Triantafillidou C,Baou K,Rontogianni D,Bouros D,Kagouridis Kdoi
10.1586/ers.13.21subject
Has Abstractpub_date
2013-06-01 00:00:00pages
289-306issue
3eissn
1747-6348issn
1747-6356journal_volume
7pub_type
杂志文章,评审abstract::Introduction: There is an unmet clinical need for improved diagnostic tests for active tuberculosis (TB) to provide high sensitivity for all cases, accelerate time to diagnosis and ensure timely and appropriate treatment. Whilst the measurement of M.tb-specific immune responses is widely used for detecting infection i...
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更新日期:2019-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1586/17476348.2015.1000867
更新日期:2015-04-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2010-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2011-08-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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