Abstract:
:Obesity has become a national epidemic and a disease of global magnitude. The numbers of patients with obesity have grown exponentially in the last 10 years to the degree that the Centers for Disease Control and Prevention reports that one third of the US population is obese. The prevalence of diabetes has grown by more than 50% in that same time period. Unfortunately, the traditional therapies of diets, exercise, behavioral modification and medications have had little effect, especially in the severely obese. The introduction of bariatric surgery has changed the natural history of the super obese. Operative approaches now provide the most effective treatment of obesity but carry with them possible risks. Only 1% of patients who are estimated to benefit from bariatric surgery have undergone a procedure. The burgeoning field of endoluminal therapy has now allowed us to consider even more minimally invasive procedures to reach a larger patient population. This article will review the most recent advances in innovative technologies to treat the growing numbers of obese patients.
journal_name
Minerva Endocrinoljournal_title
Minerva endocrinologicaauthors
Bermudez DM,Pories WJsubject
Has Abstractpub_date
2013-06-01 00:00:00pages
165-72issue
2eissn
0391-1977issn
1827-1634pii
R07Y2013N02A0165journal_volume
38pub_type
杂志文章,评审abstract::Primary hyperparathyroidism is a not uncommon disease in the elderly. A prevalence of 3% for women and 1% for men is reported in subjects aged 65 years and over. Routine serum calcium determination and parathyroid hormone radioimmuno-assay allow to make an early diagnosis in still asymptomatic subjects. In the elderly...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Hyperhomocysteinemia is a well-established risk factor for cardiovascular disease. Various factors, both modifiable and non-modifiable, interact with the homocysteine metabolism and determine the plasma homocysteine concentrations. These include genetic abnormalities, age, sex and various nutritional and hormonal dete...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract::A 49 year-old woman with anaplastic thyroid carcinoma came, for the first time, to our clinic with an enlarged supraclavicular lymph node. Ten years earlier she received a diagnosis of benign nodular goiter and has been followed up with ultrasonography, which never demonstrated any enlargement of her thyroid nodule an...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Multiple endocrine neoplasia type 1 (MEN1; formerly known as Wermer syndrome) is a rare disorder characterized by the combined occurrence of two or more tumors involving parathyroid, pancreatic islets and anterior pituitary glands; some other tumors have also been described. In most cases it is inherited in an autosom...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-03-01 00:00:00
abstract::Hyponatremia is common in neurosurgical patients and is associated with significant morbidity and mortality. Despite significant research efforts to date, we still lack a complete understanding of the pathophysiological mechanisms underlying hyponatremia in this patient setting. The purpose of this narrative review is...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-01 00:00:00
abstract::Bariatric surgery has been found to be very useful in treating established type-2 diabetes in obese persons, as well as in borderline diabetics, besides giving a good weight loss. Various modifications of the primary bariatric procedures have been introduced, with differ advantages and better efficacy. Good incretin r...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-12-01 00:00:00
abstract::Notwithstanding recent neuroendocrinological and neuroradiological findings, about 40% of carriers of pituitary adenoma still reach clinical observation and, consequently, the surgeon, in the stage of suffering from extrasellar extension to a varying degree, especially when the volumetric growth of the lesion is not a...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract:: ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.18.02852-3
更新日期:2019-03-01 00:00:00
abstract:AIM:Patients with differentiated thyroid carcinoma (DTC) are closely monitored during the first decade after diagnosis. At intervals of 1-2 years withdrawal of suppressive doses of T(4) is recommended in order to check thyroglobulin (Tg) levels under increased TSH. T(4) therapy is usually withdrawn for 5 weeks (during ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::New-onset diabetes after transplantation (NODAT) or posttransplant diabetes mellitus is a frequent metabolic complication of organ transplantation. Diabetes incidence rates among transplant recipients are higher than in the general population. The estimated rates are 9-18% after kidney, 20-33% after liver, 26-40% afte...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-09-01 00:00:00
abstract::Recent trials have reported sodium-glucose co-transporter 2 (SGLT2) inhibitors to decrease cardiac morbidity and hospitalization in diabetic patients. They have a remarkable ability to modify the cardio-renal axis and have a safer metabolic profile among the existing pharmacotherapy in diabetes. There are multiple pro...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03221-6
更新日期:2020-12-17 00:00:00
abstract::Very-low-calorie ketogenic diet (VLCKD) is a promising lifestyle intervention for the management of overweight and obesity. It is characterized by a restriction of both calories and carbohydrates, while assuring the adequate proteins, fats and micronutrients intake. Significant results in terms of excess body weight l...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03356-8
更新日期:2020-11-19 00:00:00
abstract::Many hormones and some neuropeptides and neurotransmitters play a key role in regulating numerous lymphoid cell functions. In particular, somatostatin (ss), substance P (sp) and vasoactive intestinal polypeptide (vip) appear to be involved in numerous regulating mechanisms of cell activities in the immune system under...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2001-09-01 00:00:00
abstract::Bone mineral content (CMO, mg/cm2) was measured at the distal radius by dual photon absorptiometry (DPA, I125, Am241) in 1.161 women (w), aged 20-87 years. Women were subdivided into different groups according to the presence and duration of menopause. For gross evaluation of spinal osteoporosis (OP), the results of s...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::The coexistence of Graves' disease and insulin-dependent diabetes mellitus is well known among autoimmune polyglandular syndromes and sustained by common underlying immune pathogenic factors. Hyperthyroidism itself may lead to impaired glucose tolerance in subjects with intact beta-cell function through various not we...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract:AIM:The efficacy of low and high fixed dose radioactive iodine (RAI) therapy in patients with toxic nodular goiter was investigated. METHODS:Ninety-three patients (25 males, 68 females) were included into the study (32 patients with toxic adenoma, 61 patients with toxic multinodular goiter). Patients were treated with...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00
abstract::The desire to reproduce is a base human instinct. However, for many individuals, the chances of being able to have a genetic child are compromised by a number of factors. For some, therapies aimed at treating serious medical illness, such as cancer; result in a deleterious impact on the function of eggs and sperm in t...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.17.02666-9
更新日期:2018-03-01 00:00:00
abstract::We treated with PEI 81 patients carriers of autonomous thyroid nodule, 65 toxic and 16 non toxic, all with undetectable serum TSH and suppressed extranodular tissue on scintigraphy. The treatment schedule was: 1-2 sessions per week, 1-8 ml per session, 3-13 sessions in total, In relation to the size and the therapeuti...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::For decades gross-total resection was the preferred treatment option in childhood-onset craniopharyngioma, assuming that radical strategies at the time of initial diagnosis and treatment would result in cure. Recent reports on long-term prognosis, novel treatment approaches, and molecular genetics provide new insights...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,meta分析,评审
doi:10.23736/S0391-1977.17.02615-3
更新日期:2017-12-01 00:00:00
abstract::Surgical intervention for breast cancer has continually evolved. The current review reports on updates from the pivotal trials, examines areas of controversy, and explores possible future directions. ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with well-established metabolic abnormalities. In the present study, untargeted metabolomics technology was applied to analyze the serum and follicular fluid samples from women with polycystic ovary syndrome and healthy controls using 1H nuclea...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03199-5
更新日期:2020-10-26 00:00:00
abstract::Growth hormone-releasing hormone (GHRH) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development. Decreased GHRH secretion and/or action leads to impairment of this process and somatotrope hypoplasia in both humans and experimental animals. Excessive GHRH...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract::Cushing's syndrome is a serious endocrine condition for which no treatment has been proven fully satisfactory at least for its pituitary dependent form (Cushing's disease). Indeed, despite some advances in pharmacology (cyproheptadine, bromocriptine, lisuride) and in surgical and radiation procedures at pituitary leve...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::We investigated the beta-pancreatic function in response to a standard oral glucose tolerance test (OGTT) and a tolbutamide test in a group of GH-deficient adult subjects and in a group of control subjects. Fasting plasma glucose levels were normal in all subjects; the insulin levels, basal (0.19 +/- 0.02 vs 0.99 +/- ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::In health, growth hormone (GH) is secreted in a circadian rhythm with superimposed pulsatility. Temporal fluctuations of hormone concentrations are essential for physiological action, and loss of diurnal rhythm is important in the development of disease. GH feedback occurs through the hypothalamus and involves neurope...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2003-03-01 00:00:00
abstract::A 54-year-old woman presented with an expansive mass in the anterior cervical region (front of the neck) with abscess. Laboratory tests and thyroid profile proved normal. Surgical exploration revealed a hydatid cyst in the left lobe of the thyroid gland with parasitic metastasis of the left lateral cervical lymph node...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the developed world and its pathogenesis is complex and multifactorial. It is considered the hepatic manifestation of the metabolic syndrome and is the leading cause of hepatic cirrhosis. This review aims to present current knowledge on the ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.16.02583-9
更新日期:2017-06-01 00:00:00
abstract::The major issue currently being faced in the management of prostate cancer is the inability to distinguish between indolent prostate tumors that will not present clinically from more aggressive and metastatic prostate cancers that will impact on men's lives. Only a small proportion of prostate cancers can be accounted...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-06-01 00:00:00
abstract::Loss of estrogens or androgens causes bone loss by increasing the rate of bone remodeling, and also causes an imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts. Conversely, treatment with androgens, as well as estrogens, maintains cancellous...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract::Subclinical hypothyroidism - i.e., a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels - affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviews the clinical challenges regarding, on the one hand, the si...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03176-4
更新日期:2020-08-03 00:00:00