Is there an association between fetal viral infection and fetal malformation? I. Detection of specific IgM antibodies in the serum of malformed fetuses.

Abstract:

:Determinations of IgG and IgM antibodies specific for cytomegalovirus (CMV), herpes simplex virus (HSV1), herpes simplex virus (HSV2), varicella-zoster virus (VZV), rubella, echo, Coxsackie and morbilli viruses were performed in 20 sera from malformed fetuses. Demonstration of a fetal infection by increased fetal serum IgM permits linkage to a detected fetal malformation. In parallel, 14 maternal sera and 17 amniotic fluid samples were examined. Laser nephelometry (a quantitative method) was used for the determination of IgM and IgG class immunoglobulins. None of the fetal sera were found to contain IgM class antibodies specific for the viral antigens studies. While IgM CMV-specific antibodies were present in one maternal serum, the specific IgM was absent in the fetus. The absence of specific IgM antibodies appears to warrant the conclusion that the malformed fetuses were uninfected by any of the above viruses. IgM antibodies were detected in two fetal sera by quantitative methods. The IgM antibodies present in two fetuses probably were generated in response to some other introduced antigen.

journal_name

J Perinat Med

authors

Rakocević S,Presećki V,Jurković D,Kurjak A

doi

10.1515/jpme.1990.18.2.101

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

101-9

issue

2

eissn

0300-5577

issn

1619-3997

journal_volume

18

pub_type

杂志文章
  • Myocardial infarction in early pregnancy.

    abstract::Acute myocardial infarction (AMI) during pregnancy is usually transmural and occurs in late pregnancy with a peak incidence during the peripartum or postpartum periods. We report a pregnancy-related AMI, which occurring as early as the first trimester, was treated conservatively with antithrombotic and anti-ischemic d...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2004.127

    authors: Stefanovic V,Ulander VM,Graner M,Kupari M,Kaaja R

    更新日期:2004-01-01 00:00:00

  • The effect of bilateral pelvic neurectomy on cervical ripening in pregnant rats.

    abstract:AIMS:To determine the effect of bilateral pelvic neurectomy (BPN) on cervical ripening in pregnant rats by measuring cervical extensibility and changes in collagen cross-linkages. METHODS:Timed-pregnant rats were randomly laparotomized on days 9 or 10 of gestation and the pelvic nerves were exposed and either bilatera...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2009.043

    authors: Mackay LB,Shi L,Maul H,Maner WL,Garfield RE

    更新日期:2009-01-01 00:00:00

  • Pregnancy outcomes after thyroid cancer.

    abstract::Background Thyroid cancer is one of the most common cancers in women of reproductive age. Our purpose was to evaluate the association between thyroid cancer and maternal and neonatal outcomes of pregnancy. Methods We conducted a retrospective cohort study using the Healthcare Cost and Utilization Project, Nationwide I...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2019-0039

    authors: Spiegel E,Spence AR,Czuzoj-Shulman N,Abenhaim HA

    更新日期:2019-09-25 00:00:00

  • Historical notes on immaturity. Part 1: measures of viability.

    abstract::The interest in the limit of viability originated from various sources, including legal requirements, the rejection of mechnical life support, competition for resources, concerns about handicaps, and proximity to the fetus with its limited rights. Gestational age was determined from menstrual history by Hippocratic wr...

    journal_title:Journal of perinatal medicine

    pub_type: 历史文章,杂志文章

    doi:10.1515/jpm.2011.056

    authors: Obladen M

    更新日期:2011-09-01 00:00:00

  • The management of labor in women with more than one uterine scar: is a repeat cesarean section really the only "safe" option?

    abstract::A prospective trial to investigate feasibility of vaginal delivery after more than one cesarean section, and the safety of vaginal delivery for mother and neonate. Twenty-six pregnant women with a history of two or more cesarean sections were admitted to the delivery room and accepted trial of labor under internal fet...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1994.22.1.13

    authors: Granovsky-Grisaru S,Shaya M,Diamant YZ

    更新日期:1994-01-01 00:00:00

  • Neonatal outcome in women treated for the antiphospholipid syndrome during pregnancy.

    abstract::The aim of this study was to determine the neonatal outcome in women with well-characterized antiphospholipid syndrome treated during pregnancy with low-dose aspirin. We compared 38 babies born after 36 pregnancies of 33 women diagnosed as having antiphospholipid syndrome with a group of 38 control infants matched for...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1997.25.2.192

    authors: Botet F,Romera G,Montagut P,Figueras J,Carmona F,Balasch J

    更新日期:1997-01-01 00:00:00

  • The value of ultrasonographic examination of the uterine cervix in predicting post-term pregnancy.

    abstract:OBJECT:To assess whether transvaginal ultrasound is helpful in predicting the post-term onset of labor (> or = 1 weeks). SETTING:Antenatal clinic of a University hospital and referral center. SUBJECT AND MEHODS: One hundred and twenty singleton uncomplicated pregnancies in primiparous women were enrolled at 37 weeks o...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2001.045

    authors: Vimercati A,Greco P,Lopalco P,Loizzi V,Scioscia M,Mei L,Rossi AC,Selvaggi L

    更新日期:2001-01-01 00:00:00

  • Birth-weight centiles and the risk of serious adverse neonatal outcomes at term.

    abstract:BACKGROUND:Birth-weight is an important determinant of perinatal outcome with low birth-weight being a particular risk factor for adverse consequences. AIM:To investigate the impact of neonatal sex, mode of birth and gestational age at birth according to birth-weight centile on serious adverse neonatal outcomes in sin...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2017-0176

    authors: Yu J,Flatley C,Greer RM,Kumar S

    更新日期:2018-11-27 00:00:00

  • Effects of coronavirus 19 pandemic on maternal anxiety during pregnancy: a prospectic observational study.

    abstract::Objectives Coronavirus (COVID-19) is a new respiratory disease that is spreading widely throughout the world. The aim of this study was to evaluate the psychological impact of COVID-19 pandemic on pregnant women in Italy. Methods We considered 200 pregnancies attending our antenatal clinic. A questionnaire was sent to...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2020-0182

    authors: Mappa I,Distefano FA,Rizzo G

    更新日期:2020-07-28 00:00:00

  • A rare presentation of Pompe disease with massive hypertrophic cardiomyopathy at birth.

    abstract::We report a term infant with Pompe disease presenting in the immediate newborn period. The infant was born at 40 weeks' gestation, weighing 3600 g to a 32 year-old black female. Infant presented at delivery with massive hypertrophic cardiomyopathy and pulmonary hypertension. Diagnosis was confirmed by low alpha-glucos...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2002.081

    authors: Noori S,Acherman R,Siassi B,Luna C,Ebrahimi M,Pavlova Z,Ramanathan R

    更新日期:2002-01-01 00:00:00

  • Alternatives to the antenatal glucocorticoid treatment for the prevention of respiratory distress syndrome.

    abstract::Various substances and methods are used as alternatives to corticoids for stimulating antenatal pulmonary maturation. This study discusses thyroid hormones, intralipid, ambroxol, carnitine, theophylline (aminophylline) and betasympathomimetic agents. ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1987.15.5.453

    authors: Dudenhausen JW

    更新日期:1987-01-01 00:00:00

  • Organization of neonatal care services and its importance.

    abstract::Universally 4 million newborns die and another 4 million are stillborn every year. 98% of these neonatal deaths take place in the developing countries. Looking at the state of the world's newborns one can see that neonatal mortality rate is about 4-5 per 1000 in the developed countries and nearly 10 fold this in the d...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2003.060

    authors: Atasay B,Arsan S

    更新日期:2003-01-01 00:00:00

  • Endocervical immune mediator production following successful rescue or ultrasound indicated cerclage placement.

    abstract:OBJECTIVE:Placement of a cervical cerclage at mid-trimester in women at risk for preterm labor is a common procedure with apparent benefits for some women. However, the changes that occur in the cervix following this procedure remain incompletely identified. METHODS:We evaluated the endocervical concentrations of medi...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2011.132

    authors: Kanninen TT,Herway C,Skupski DW,Eglinton GS,Witkin SS

    更新日期:2011-11-25 00:00:00

  • Does labor start too late?

    abstract::To determine the optimal time of delivery, in terms of lowest risk of peripartum complications, the relative incidences of the parameters. Abnormal cardiotocogram (CTG), operative vaginal delivery, Apgar < 7 at 1 and 5 min, artery cord blood pH < 7.20, blood loss > 500 ml, epidural anesthesia, and Cesarean section, we...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1996.24.6.661

    authors: Unger C,Zimmermann R,Huch A,Huch R

    更新日期:1996-01-01 00:00:00

  • Assessing the utility of the Healthy Start Screen to predict an elevated Edinburgh Postnatal Depression Scale score.

    abstract::Objective To examine the utility of the Healthy Start Screen (HSS), which is an assessment of health, environment, and behavioral risk factors offered to all pregnant women in the state of Florida, in identifying women at risk for developing postpartum depression (PPD). Methods The sample for this Institutional Review...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2019-0472

    authors: Padilla MM,Roussos-Ross D,Goodin AJ

    更新日期:2020-06-25 00:00:00

  • MRI during pregnancy.

    abstract::The use of ultrasonography (USG) during pregnancy provides a tremendous amount of valuable information about fetal and maternal well-being. However, in some cases the image quality may be poor due to maternal fat tissue, fetal position, or some other reason. Magnetic resonance imaging (MRI) can provide clear images fr...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2003.070

    authors: Kawabata I,Takahashi Y,Iwagaki S,Tamaya T

    更新日期:2003-01-01 00:00:00

  • The role of ultrasonography in recognizing the cause of fetal cerebral ventriculomegaly.

    abstract::Dilatation of the fetal cerebral ventricles (ventriculomegaly) is a generic sonographic sign common to several pathological entities carrying different prognoses. The main causes of fetal ventriculomegaly are aqueductal stenosis, Chiari II malformation, Dandy-Walker complex and agenesis of the corpus callosum. Ventric...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2004.002

    authors: D'Addario V

    更新日期:2004-01-01 00:00:00

  • Prematurity and maternal bronchial hyperresponsiveness.

    abstract::Bronchial reactivity was compared among mothers of neonates with unexplained premature delivery and mothers of preterm neonates with known etiology of prematurity as well as mothers who delivered their children at term. Bronchial reactivity was measured by unspecific bronchial provocation testing with histamine. A sig...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1989.17.2.151

    authors: Riedel F,Achenbach U,Rieger CH

    更新日期:1989-01-01 00:00:00

  • MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.

    abstract:AIM:The present study attempts to understand the role of methylenetetrahydrofolate reductase C677T (MTHFR C677T) in recurrent pregnancy losses in North Indian women because of hyperhomocysteinemia in light of serum folate and vitamin B₁₂. METHODS:One hundred and seven women with three or more consecutive unexplained r...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2012-0252

    authors: Puri M,Kaur L,Walia GK,Mukhopadhhyay R,Sachdeva MP,Trivedi SS,Ghosh PK,Saraswathy KN

    更新日期:2013-09-01 00:00:00

  • Predicting neonatal respiratory morbidity by lamellar body count and gestational age.

    abstract:AIMS:To develop a predictive model for assessing the risk of developing neonatal respiratory morbidity using lamellar body counts (LBCs) and gestational age (GA) to provide a more patient-specific assessment. METHODS:Retrospective cohort study of patients' ≥32 weeks' gestation who received amniocentesis with LBC analy...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2014-0310

    authors: Beamon C,Carlson L,Rambally B,Berchuck S,Gearhart M,Hammett-Stabler C,Strauss R

    更新日期:2016-08-01 00:00:00

  • Limit of viability in Japan: ethical consideration.

    abstract::Viability means "the quality or state of being able to live, grow and develop." Limit of viability has been changed along with the advancement of perinatal and neonatal medicine. The viability limit defined in the Japanese Motherhood Protection Act was amended from 24 to 22 completed weeks of gestation in 1991 based o...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2009.112

    authors: Nishida H,Sakuma I

    更新日期:2009-01-01 00:00:00

  • Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study.

    abstract:OBJECTIVE:To compare the incidence of twin births and their birth weight characteristics in mothers aged > or = 40 years with those of mothers aged 35-39 years. METHODS:We used a population-based cohort of Israeli twins delivered between 1993-98 to compare birth weight characteristics of 510 and 2102 twin pairs delive...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2001.016

    authors: Blickstein I,Goldman RD,Mazkereth R

    更新日期:2001-01-01 00:00:00

  • The use of culture-independent tools to characterize bacteria in endo-tracheal aspirates from pre-term infants at risk of bronchopulmonary dysplasia.

    abstract::Although premature infants are increasingly surviving the neonatal period, up to one-third develop bronchopulmonary dysplasia (BPD). Despite evidence that bacterial colonization of the neonatal respiratory tract by certain bacteria may be a risk factor in BPD development, little is known about the role these bacteria ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.026

    authors: Stressmann FA,Connett GJ,Goss K,Kollamparambil TG,Patel N,Payne MS,Puddy V,Legg J,Bruce KD,Rogers GB

    更新日期:2010-05-01 00:00:00

  • Evaluation of the fetal state by automatic analysis of the heart rate. 2. Deceleration areas and umbilical artery blood pH.

    abstract::Fetal heart rate (FHR) deceleration areas were studied to obtain by objective measurement of the FHR, their prognostic value of the new-born state. 1. There is a reasonably good correlation between FHR deceleration areas and UApH (Tab. II). Such a correlation was found by SHELLEY and TIPTON [6] for the whole decelerat...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1976.4.2.118

    authors: Tournaire M,Sturbois G,Ripoche A,Le Houezec R,Breart G,Chavinie J,Sureau C

    更新日期:1976-01-01 00:00:00

  • Plasma angiotensin II and blood pressure changes during dietary sodium manipulation.

    abstract::The renin-angiotensin system and dietary sodium have been repeatedly implicated in the pathogenesis of pregnancy induced hypertension (PIH). Mechanisms responsible for increased vascular responsiveness to angiotensin II (A-II) observed in PIH are not completely understood. Plasma A-II levels and blood pressure are fun...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1984.12.4.167

    authors: Lee MI,Sokol RJ,Todd H

    更新日期:1984-01-01 00:00:00

  • Computerized cardiotocography parameters in pregnant women affected by pregestational diabetes mellitus.

    abstract:AIM:To evaluate whether computerized CTG (cCTG) is a reliable method of predicting neonatal outcome in pregnancies complicated by pregestational diabetes at term. PATIENTS AND METHODS:We considered 27 pregnant women affected by pregestational diabetes and 46 normal pregnancies as controls that fulfilled the following ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2004.141

    authors: Ruozi-Berretta A,Piazze JJ,Cosmi E,Cerekja A,Kashami A,Anceschi MM

    更新日期:2004-01-01 00:00:00

  • Meconium peritonitis secondary to torsion of fallopian tube cyst and transient central diabetes insipidus in a preterm infant.

    abstract::Meconium peritonitis is a sterile chemical peritonitis caused by peritoneal seeding of meconium from an antenatal gastrointestinal perforation. We report a 32-week preterm female neonate who developed meconium peritonitis due to bowel perforation, secondary to a twisted left fallopian tube mass, which was excised and ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2005.014

    authors: Manikoth P,Vaishnav A,Zachariah N,Sajwani MJ,Nair AK,Pai MG

    更新日期:2005-01-01 00:00:00

  • A considerable asymptomatic proportion and thromboembolism risk of pregnant women with COVID-19 infection in Wuhan, China.

    abstract:Objectives:The coronavirus disease 2019 (COVID-19) had become a worldwide pandemic, however, information is limited on the asymptomatic proportion and thromboembolism risk of pregnant women with infection. Methods:All 32 pregnant women with COVID-19 who were admitted to the hospital in Wuhan during the outbreak from J...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2020-0409

    authors: Wang Y,Liang X,Wang H,Li L,Xiong G,Mi L

    更新日期:2020-11-23 00:00:00

  • Growth attainment in German children born preterm, and cardiovascular risk factors in adolescence. Analysis of the population representative KiGGS data.

    abstract:AIM:To compare the growth attainment of preterm children and their cardiovascular risk factors at adolescence with the values measured in term children in Germany. METHODS:About 17,641 children aged 0 to <18 years were studied between 2003 and 2006 in the population representative German KiGGS survey ("German Health I...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2016-0294

    authors: Bergmann RL,Bergmann KE,Richter R,Schlaud M,Henrich W,Weichert A

    更新日期:2017-07-26 00:00:00

  • The efficacy of first-trimester PAPP-A and free beta hCG levels for predicting adverse pregnancy outcome.

    abstract:OBJECTIVE:To determine whether first-trimester measurements of maternal serum PAPP-A and free beta hCG levels were associated with adverse pregnancy outcomes. STUDY DESIGN:First trimester maternal serum free beta hCG and PAPP-A were measured in 490 singleton pregnancies. Pregnancies were followed by the fetal-maternal...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2006.026

    authors: Kavak ZN,Basgul A,Elter K,Uygur M,Gokaslan H

    更新日期:2006-01-01 00:00:00