Alterations in gene expression in Caenorhabditis elegans associated with organophosphate pesticide intoxication and recovery.

abstract：BACKGROUND:Engineered nanomaterials may release nanosized residues, by degradation, throughout their life cycle. These residues may be a threat for living organisms. They may be ingested by humans through food and water. Although the toxicity of pristine CeO2 nanoparticles (NPs) has been documented, there is a lack of ...

journal_title：BMC genomics

authors： Fisichella M,Berenguer F,Steinmetz G,Auffan M,Rose J,Prat O

更新日期：2014-08-21 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are short noncoding RNAs (approximately 22 nucleotides in length) that play important roles in colorectal cancer (CRC) progression through silencing gene expression. Numerous dysregulated miRNAs simultaneously participate in the process of colon cancer development. However, the detailed me...

journal_title：BMC genomics

authors： Chen WS,Chen TW,Yang TH,Hu LY,Pan HW,Leung CM,Li SC,Ho MR,Shu CW,Liu PF,Yu SY,Tu YT,Lin WC,Wu TT,Tsai KW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Genes, RNAs, and proteins play important roles during germline development. However, the functions of non-coding RNAs (ncRNAs) on germline development remain unclear in avian species. Recent high-throughput techniques have identified several classes of ncRNAs, including micro RNAs (miRNAs), small-interfering...

journal_title：BMC genomics

authors： Rengaraj D,Lee SI,Park TS,Lee HJ,Kim YM,Sohn YA,Jung M,Noh SJ,Jung H,Han JY

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:Gibel carp is an important aquaculture species in China, and a herpesvirus, called as Carassius auratus herpesvirus (CaHV), has hampered the aquaculture development. Diverse gynogenetic clones of gibel carp have been identified or created, and some of them have been used as aquaculture varieties, but their r...

journal_title：BMC genomics

authors： Gao FX,Wang Y,Zhang QY,Mou CY,Li Z,Deng YS,Zhou L,Gui JF

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:Mitochondrial genomes of flowering plants (angiosperms) are highly dynamic in genome structure. The mitogenome of the earliest angiosperm Amborella is remarkable in carrying rampant foreign DNAs, in contrast to Liriodendron, the other only known early angiosperm mitogenome that is described as 'fossilized'. ...

journal_title：BMC genomics

authors： Dong S,Zhao C,Chen F,Liu Y,Zhang S,Wu H,Zhang L,Liu Y

更新日期：2018-08-14 00:00:00

abstract：BACKGROUND:As is true for many other antibiotic-resistant Gram-negative pathogens, members of the Burkholderia cepacia complex (BCC) are currently being assessed for their susceptibility to phage therapy as an antimicrobial treatment. The objective of this study was to perform genomic and limited functional characteriz...

journal_title：BMC genomics

authors： Lynch KH,Abdu AH,Schobert M,Dennis JJ

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:In a previous genome-wide analysis of FXR binding to hepatic chromatin, we noticed that an extra nuclear receptor (NR) half-site was co-enriched close to the FXR binding IR-1 elements and we provided limited support that the monomeric LRH-1 receptor that binds to NR half-sites might function together with FX...

journal_title：BMC genomics

authors： Chong HK,Biesinger J,Seo YK,Xie X,Osborne TF

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Simple Sequence Repeats (SSRs) are widely used in population genetic studies but their classical development is costly and time-consuming. The ever-increasing available DNA datasets generated by high-throughput techniques offer an inexpensive alternative for SSRs discovery. Expressed Sequence Tags (ESTs) hav...

journal_title：BMC genomics

authors： Lopez L,Barreiro R,Fischer M,Koch MA

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:The floral transition plays a vital role in the life of ornamental plants. Despite progress in model plants, the molecular mechanisms of flowering regulation remain unknown in perennial plants. Rosa chinensis 'Old Blush' is a unique plant that can flower continuously year-round. In this study, gene expressio...

journal_title：BMC genomics

authors： Guo X,Yu C,Luo L,Wan H,Zhen N,Xu T,Tan J,Pan H,Zhang Q

更新日期：2017-02-23 00:00:00

abstract：BACKGROUND:A better understanding of the genetic architecture underlying complex traits (e.g., the distribution of causal variants and their effects) may aid in the genomic prediction. Here, we hypothesized that the genomic variants of complex traits might be enriched in a subset of genomic regions defined by genes gro...

journal_title：BMC genomics

authors： Fang L,Sahana G,Ma P,Su G,Yu Y,Zhang S,Lund MS,Sørensen P

更新日期：2017-08-10 00:00:00

abstract：BACKGROUND:Boar taint is observed in a high proportion of uncastrated male pigs and is characterized by an unpleasant odor/flavor in cooked meat, primarily caused by elevated levels of androstenone and skatole. Androstenone is a steroid produced in the testis in parallel with biosynthesis of other sex steroids like tes...

journal_title：BMC genomics

authors： Grindflek E,Lien S,Hamland H,Hansen MH,Kent M,van Son M,Meuwissen TH

更新日期：2011-07-13 00:00:00

abstract：BACKGROUND:Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome research. Although many quality metrics have been proposed and sof...

journal_title：BMC genomics

authors： Yavas G,Hong H,Xiao W

更新日期：2019-09-11 00:00:00

abstract：BACKGROUND:The ubiquitin-conjugating enzyme HR6B is required for spermatogenesis in mouse. Loss of HR6B results in aberrant histone modification patterns on the trancriptionally silenced X and Y chromosomes (XY body) and on centromeric chromatin in meiotic prophase. We studied the relationship between these chromatin m...

journal_title：BMC genomics

authors： Mulugeta Achame E,Wassenaar E,Hoogerbrugge JW,Sleddens-Linkels E,Ooms M,Sun ZW,van IJcken WF,Grootegoed JA,Baarends WM

更新日期：2010-06-10 00:00:00

abstract：BACKGROUND:The Pacific oyster Crassostrea gigas is an important fishery resource that is sensitive to temperature fluctuations. Thus, it has evolved a protection mechanism against heat stress by increasing the expression of the gene coding for heat shock protein (HSP) 70 under elevated temperatures. In other animals, h...

journal_title：BMC genomics

authors： Liu Y,Li L,Huang B,Wang W,Zhang G

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:Ashbya gossypii is a filamentous Saccharomycete used for the industrial production of riboflavin that has been recently explored as a host system for recombinant protein production. To gain insight into the protein secretory pathway of this biotechnologically relevant fungus, we undertook genome-wide analyse...

journal_title：BMC genomics

authors： Aguiar TQ,Ribeiro O,Arvas M,Wiebe MG,Penttilä M,Domingues L

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:The response of the trout, O. mykiss, head kidney to bacterial lipopolysaccharide (LPS) or active and attenuated infectious hematopoietic necrosis virus (IHNV and attINHV respectively) intraperitoneal challenge, 24 and 72 hours post-injection, was investigated using a salmonid-specific cDNA microarray. RESU...

journal_title：BMC genomics

authors： MacKenzie S,Balasch JC,Novoa B,Ribas L,Roher N,Krasnov A,Figueras A

更新日期：2008-03-26 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenases (ADHs) in plants are encoded by a multigene family. ADHs participate in growth, development, and adaptation in many plant species, but the evolution and function of the ADH gene family in sugarcane is still unclear. RESULTS:In the present study, 151 ADH genes from 17 species including...

journal_title：BMC genomics

authors： Su W,Ren Y,Wang D,Su Y,Feng J,Zhang C,Tang H,Xu L,Muhammad K,Que Y

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and defines a relatively uniform category, although only some patients suffer very late relapse. TEL/AM...

journal_title：BMC genomics

authors： Gandemer V,Rio AG,de Tayrac M,Sibut V,Mottier S,Ly Sunnaram B,Henry C,Monnier A,Berthou C,Le Gall E,Le Treut A,Schmitt C,Le Gall JY,Mosser J,Galibert MD

更新日期：2007-10-23 00:00:00

abstract：BACKGROUND:Williams syndrome transcription factor (WSTF) is a multifaceted protein that is involved in several nuclear processes, including replication, transcription, and the DNA damage response. WSTF participates in a chromatin-remodeling complex with the ISWI ATPase, SNF2H, and is thought to contribute to the mainte...

journal_title：BMC genomics

authors： Culver-Cochran AE,Chadwick BP

更新日期：2013-10-29 00:00:00

abstract：BACKGROUND:Whole mitogenomes or short fragments (i.e., 300-700 bp of the cox1 gene) are the markers of choice for revealing within- and among-species genealogies. Protocols for sequencing and assembling mitogenomes include 'primer walking' or 'long PCR' followed by Sanger sequencing or Illumina short-read low-coverage ...

journal_title：BMC genomics

authors： Baeza JA

更新日期：2020-12-09 00:00:00

abstract：BACKGROUND:Urechis unicinctus, an echiuran worm inhabiting the U-shaped burrows in the coastal mud flats, is an important commercial and ecological invertebrate in Northeast Asian countries, which has potential applications in the study of animal evolution, coastal sediment improvement and marine drug development. Furt...

journal_title：BMC genomics

authors： Liu X,Zhang L,Zhang Z,Ma X,Liu J

更新日期：2015-10-21 00:00:00

abstract：BACKGROUND:The laying hen model of spontaneous epithelial ovarian cancer (EOC) is unique in that it is the only model that enables observations of early events in disease progression and is therefore also uniquely suited for chemoprevention trials. Previous studies on the effect of dietary flaxseed in laying hens have ...

journal_title：BMC genomics

authors： Hales KH,Speckman SC,Kurrey NK,Hales DB

更新日期：2014-08-24 00:00:00

abstract：BACKGROUND:Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities. Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel superfamily. Here we report the c...

journal_title：BMC genomics

authors： Falardeau JL,Kennedy JC,Acierno JS Jr,Sun M,Stahl S,Goldin E,Slaugenhaupt SA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Fusion genes are known to be drivers of many common cancers, so they are potential markers for diagnosis, prognosis or therapy response. The advent of paired-end RNA sequencing enhances our ability to discover fusion genes. While there are available methods, routine analyses of large number of samples are st...

journal_title：BMC genomics

authors： Vu TN,Deng W,Trac QT,Calza S,Hwang W,Pawitan Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Pectins are plant cell wall polysaccharides that can be acetylated on C2 and/or C3 of galacturonic acid residues. The degree of acetylation of pectin can be modulated by pectin acetylesterase (EC 3.1.1.6, PAE). The function and structure of plant PAEs remain poorly understood and the role of the fine-tuning ...

journal_title：BMC genomics

authors： Philippe F,Pelloux J,Rayon C

更新日期：2017-06-08 00:00:00

abstract：BACKGROUND:By assaying hundreds of thousands of single nucleotide polymorphisms, genome wide association studies (GWAS) allow for a powerful, unbiased review of the entire genome to localize common genetic variants that influence health and disease. Although it is widely recognized that some correction for multiple tes...

journal_title：BMC genomics

authors： Duggal P,Gillanders EM,Holmes TN,Bailey-Wilson JE

更新日期：2008-10-31 00:00:00

abstract：BACKGROUND:The σ(54) subunit controls a unique class of promoters in bacteria. Such promoters, without exception, require enhancer binding proteins (EBPs) for transcription initiation. Desulfovibrio vulgaris Hildenborough, a model bacterium for sulfate reduction studies, has a high number of EBPs, more than most sequen...

journal_title：BMC genomics

authors： Kazakov AE,Rajeev L,Chen A,Luning EG,Dubchak I,Mukhopadhyay A,Novichkov PS

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Pantoea ananatis is found in a wide range of natural environments, including water, soil, as part of the epi- and endophytic flora of various plant hosts, and in the insect gut. Some strains have proven effective as biological control agents and plant-growth promoters, while other strains have been implicate...

journal_title：BMC genomics

authors： De Maayer P,Chan WY,Rubagotti E,Venter SN,Toth IK,Birch PR,Coutinho TA

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:Decapods are an order of crustaceans which includes shrimps, crabs, lobsters and crayfish. They occur worldwide and are of great scientific interest as well as being of ecological and economic importance in fisheries and aquaculture. However, our knowledge of their biology mainly comes from the group which i...

journal_title：BMC genomics

authors： Nong W,Chai ZYH,Jiang X,Qin J,Ma KY,Chan KM,Chan TF,Chow BKC,Kwan HS,Wong CKC,Qiu JW,Hui JHL,Chu KH

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa is an opportunistic pathogen with a high incidence of hospital infections that represents a threat to immune compromised patients. Genomic studies have shown that, in contrast to other pathogenic bacteria, clinical and environmental isolates do not show particular genomic differences. ...

journal_title：BMC genomics

authors： Grosso-Becerra MV,Santos-Medellín C,González-Valdez A,Méndez JL,Delgado G,Morales-Espinosa R,Servín-González L,Alcaraz LD,Soberón-Chávez G

更新日期：2014-04-28 00:00:00