Anal and perianal squamous carcinomas and high-grade intraepithelial lesions exclusively associated with "low-risk" HPV genotypes 6 and 11.

abstract：:Interval breast cancer (IC) has a more aggressive phenotype and higher mortality than screen-detected cancer (SDC). In this case-case study, we investigated whether the size of longitudinal fluctuations in mammographic percent density (PD fluctuation) was associated with the ratio of IC versus SDC among screened women...

journal_title：International journal of cancer

authors： Strand F,Humphreys K,Eriksson M,Li J,Andersson TM,Törnberg S,Azavedo E,Shepherd J,Hall P,Czene K

更新日期：2017-01-01 00:00:00

abstract：:Survival for breast cancer (BC) is lower in eastern than northern/central Europe, and in older than younger women. We analysed how comorbidities at diagnosis affected whether selected standard treatments (STs) were given, across Europe and over time, also assessing consequences for survival/relapse. We analysed 7581 s...

journal_title：International journal of cancer

authors： Minicozzi P,Van Eycken L,Molinie F,Innos K,Guevara M,Marcos-Gragera R,Castro C,Rapiti E,Katalinic A,Torrella A,Žagar T,Bielska-Lasota M,Giorgi Rossi P,Larrañaga N,Bastos J,Sánchez MJ,Sant M,European HR Working Group on

更新日期：2019-05-01 00:00:00

abstract：:Altered microRNA (miRNA) expression has been found to promote carcinogenesis, but little is known about the role of miRNAs in esophageal cancer. In this study, we selected 10 miRNAs and analyzed their expression in 10 esophageal cancer cell lines and 158 tissue specimens using Northern blotting and in situ hybridizati...

journal_title：International journal of cancer

authors： Hu Y,Correa AM,Hoque A,Guan B,Ye F,Huang J,Swisher SG,Wu TT,Ajani JA,Xu XC

更新日期：2011-01-01 00:00:00

abstract：:The effects on breast cancer mortality seen after 16 years of biennial screening of younger women are assessed in this prospective cohort study. Since 1975 some 13,500 women, aged 35-49 in 1975, were invited to participate in the Nijmegen screening programme comprising a mammographic examination every 2 years. By the ...

journal_title：International journal of cancer

authors： Peer PG,Werre JM,Mravunac M,Hendriks JH,Holland R,Verbeek AL

更新日期：1995-03-16 00:00:00

abstract：:Rapid growth of residual tumor after partial hepatectomy has been observed during the period of liver regeneration in children with malignant embryonal hepatoblastoma. The aim of this study was to elucidate the role of hepatocyte growth-factor-scatter factor (HGF-SF) in this phenomenon. Markedly increased serum levels...

journal_title：International journal of cancer

authors： von Schweinitz D,Faundez A,Teichmann B,Birnbaum T,Koch A,Hecker H,Glüer S,Fuchs J,Pietsch T

更新日期：2000-01-15 00:00:00

abstract：:Osteosarcoma incidence rates in the United States peak in adolescence and in the elderly. The international patterns of osteosarcoma incidence in children have been described, whereas those for young, middle age or elderly adults have not. Using the Cancer Incidence in Five Continents, International Agency for Cancer ...

journal_title：International journal of cancer

authors： Mirabello L,Troisi RJ,Savage SA

更新日期：2009-07-01 00:00:00

abstract：:Exfoliated nasopharyngeal (NP) cells from 62 normal Cantonese Chinese having IgA/VCA antibodies for more than a year and from 39 similar persons without IgA/VCA antibodies, were tested for the presence of EBV/DNA sequences by spot followed by blot hybridization tests, using the cloned internal repeat of B95-8 viral DN...

journal_title：International journal of cancer

authors： Desgranges C,Pi GH,Bornkamm GW,Legrand C,Zeng Y,de-Thé G

更新日期：1983-11-15 00:00:00

abstract：:Metastatic tumor formation via vessel route begins with cancer cell extravasation from vessel lumen, migration into the connective tissue surrounding vessels, and invasion into target organ parenchyma. Epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) have been recognized to play an i...

journal_title：International journal of cancer

authors： Aokage K,Ishii G,Ohtaki Y,Yamaguchi Y,Hishida T,Yoshida J,Nishimura M,Nagai K,Ochiai A

更新日期：2011-04-01 00:00:00

abstract：:Signal transducer and activator of transcription 5b (STAT5b) is likely the relevant STAT5 isoform with respect to the process of malignant progression in gliomas. STAT5b is a latent cytoplasmic protein involved in cell signaling through the modulation of growth factors, apoptosis, and angiogenesis. Previous in vitro s...

journal_title：International journal of cancer

authors： Gressot LV,Doucette TA,Yang Y,Fuller GN,Heimberger AB,Bögler O,Rao A,Latha K,Rao G

更新日期：2015-05-01 00:00:00

abstract：:While platelet-derived growth factor, PDGF, is not regularly expressed in mesenchymal tissues, PDGF B mRNA is often found in tumors derived from these tissues. PDGF B protein is also present, but the protein levels in individual tumors do not appear to correlate well with those of the mRNA. PDGF B is homologous to the...

journal_title：International journal of cancer

authors： Heller S,Scheibenpflug L,Westermark B,Nistér M

更新日期：2000-01-15 00:00:00

abstract：:The matrix metalloproteinase (MMP) family of proteins mediates various cellular pathways, including apoptosis and angiogenesis. Polymorphisms of MMP genes are associated with increased esophageal adenocarcinoma (EAC) risk. Gastroesophageal reflux disease (GERD) is an established EAC risk factor. We examined whether MM...

journal_title：International journal of cancer

authors： Cheung WY,Zhai R,Bradbury P,Hopkins J,Kulke MH,Heist RS,Asomaning K,Ma C,Xu W,Wang Z,Hooshmand S,Su L,Christiani DC,Liu G

更新日期：2012-12-01 00:00:00

abstract：:In previous studies we showed that human sarcoma and melanoma cell lines synthesize and secrete into culture medium a glycoprotein, migrating in urea sodium dodecyl sulfate-polyacrylamide gel electrophoresis at Mr 140,000. It is not detected in cultures of the corresponding normal cells. Conditioned medium of the mela...

journal_title：International journal of cancer

authors： Bízik J,Vaheri A,Saksela O,Kalkkinen N,Meri S,Grófóva M

更新日期：1986-01-15 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta) inhibits epithelial cell proliferation. Inactivation of the TGF-beta signaling pathway is thought to play a role in tumorigenesis. Our purpose was to clarify the correlation between TGF-beta receptors or TGF-beta 1 expression and the clinicopathologic characteristics of patie...

journal_title：International journal of cancer

authors： Fukai Y,Fukuchi M,Masuda N,Osawa H,Kato H,Nakajima T,Kuwano H

更新日期：2003-03-20 00:00:00

abstract：:Nanoparticle-based phototherapies, such as photothermal therapy (PTT) and photodynamic therapy (PDT), exhibit strong efficacy, minimal invasion and negligible side effects in tumor treatment. These phototherapies have received considerable attention and been extensively studied in recent years. In addition to directly...

journal_title：International journal of cancer

authors： Hou X,Tao Y,Pang Y,Li X,Jiang G,Liu Y

更新日期：2018-12-15 00:00:00

abstract：:We obtained Thy-I-positive cells directly from growing methylcholanthrene-induced (MCA-1510) sarcomas using fluorescence-activated cell sorting, then cultured these lymphocytes in medium containing Interleukin-2 and tested their activity in vivo against various MCA-sarcoma lines with the Winn assay. We found that cult...

journal_title：International journal of cancer

authors： Mulé JJ,Forstrom JW,George E,Hellström I,Hellström KE

更新日期：1981-11-15 00:00:00

abstract：:There is strong evidence of a protection of high consumption of plant foods against squamous cell carcinoma of the oesophagus, but the respective role of fruits and vegetables is not well elucidated. In the time period 1996-2003, a case-control study designed in order to address this question was conducted in Uruguay....

journal_title：International journal of cancer

authors： De Stefani E,Boffetta P,Deneo-Pellegrini H,Ronco AL,Correa P,Mendilaharsu M

更新日期：2005-08-10 00:00:00

abstract：:In order to examine the role of cell surface laminin in tumor metastasis we have utilized four well-characterized murine fibrosarcoma cell lines. Two of these lines were highly metastatic when injected into syngeneic mice while the remaining two lines were significantly less metastatic. Using indirect immunofluorescen...

journal_title：International journal of cancer

authors： Malinoff HL,McCoy JP Jr,Varani J,Wicha MS

更新日期：1984-05-15 00:00:00

abstract：:The hypothesis has been advanced that deformation-induced lethal mechanical trauma, resulting in surface-membrane rupture, is inflicted on circulating cancer cells trapped in the microcirculation, and that this rapid cell-killing mechanism is a potentially important rate regulator for hematogenous metastasis. We descr...

journal_title：International journal of cancer

authors： Weiss L,Nannmark U,Johansson BR,Bagge U

更新日期：1992-01-02 00:00:00

abstract：:A significant proportion of screen-detected men with prostate cancer is likely to be overtreated, especially in older age groups. We aim to find which groups of screen-detected older men (65+) benefit the most from Immediate Radical Treatment or Active Surveillance (AS) for prostate cancer, depending on age, screening...

journal_title：International journal of cancer

authors： de Carvalho TM,Heijnsdijk EA,de Koning HJ

更新日期：2016-05-15 00:00:00

abstract：:A population-based case-control study was conducted to examine the effect of ingestion of vitamin C, carotenoids and retinol on risk of pharyngeal cancer. Data were available from 166 cases of pharyngeal cancer or their next-of-kin, and from 547 controls similar in age and sex to the cases. Odds ratios (ORs) relating ...

journal_title：International journal of cancer

authors： Rossing MA,Vaughan TL,McKnight B

更新日期：1989-10-15 00:00:00

abstract：:By transmission and scanning electron microscopic studies of MC-29 virus-infected CEC cultures, C-type virus particles were detected in the medium of infected cultures, in infected cells and in intracellular vacuoles. Virus budding was also observed. In the scanning electron microscope (SEM) so-called blebs appeared o...

journal_title：International journal of cancer

authors： Podmaniczky E,Szende B,Lapis K,Ferenc G

更新日期：1976-10-15 00:00:00

abstract：:IL-10 mRNA expression and protein production in established melanoma cell lines and freshly cultured primary and metastatic melanoma cells was examined. The in situ distribution of IL-10 in native melanoma tissue was also investigated by immunohistochemistry in primary tumors, metastases, benign melanocytic nevi and n...

journal_title：International journal of cancer

authors： Dummer W,Bastian BC,Ernst N,Schänzle C,Schwaaf A,Bröcker EB

更新日期：1996-05-29 00:00:00

abstract：:We present a pilot study that aims to examine the possibility to easily and noninvasively detect and discriminate females with ovarian cancer (OC) from females that have no tumor(s) and from females that have benign genital tract neoplasia, using exhaled breath samples. The study is based on clinical samples and data ...

journal_title：International journal of cancer

authors： Amal H,Shi DY,Ionescu R,Zhang W,Hua QL,Pan YY,Tao L,Liu H,Haick H

更新日期：2015-03-15 00:00:00

abstract：:Morphologic and metabolic studies have been carried out on Friend leukemia cell (FLC) tumors (grown in DBA/2 mice) or fibrosarcomas (grown in C3H/HeN or C3H/HeJ mice) shortly after peritumoral injection of recombinant mouse tumor necrosis factor (TNF) alpha. Marked vascular congestion and focal extravasation of erythr...

journal_title：International journal of cancer

authors： Proietti E,Belardelli F,Carpinelli G,Di Vito M,Woodrow D,Moss J,Sestili P,Fiers W,Gresser I,Podo F

更新日期：1988-10-15 00:00:00

abstract：:This report describes maternal and perinatal risk factors for Wilms' tumor analyzed in a case-control study nested in a nationwide cohort in Sweden. The Swedish National Cancer Registry ascertained 110 cases from among successive birth cohorts from 1973 through 1984, identified by the Swedish Medical Birth Registry, t...

journal_title：International journal of cancer

authors： Lindblad P,Zack M,Adami HO,Ericson A

更新日期：1992-04-22 00:00:00

abstract：:The hedgehog (Hh) signaling pathway is essential for the development of tissues and organs. Hyperactive Hh signaling has been implicated in many gastric cancers, including esophageal cancer. However, the interaction between the Hh pathway and other potential signaling pathways in primary esophageal tumorigenesis has n...

journal_title：International journal of cancer

authors： Wei L,Xu Z

更新日期：2011-07-15 00:00:00

abstract：:PDT has been reported to induce cancer cell expression of cytokines, such as IL-6 and TNF-alpha, but it has been unclear whether cytokine expression by cancer cells is directly related to the antitumor effect of PDT. We treated Lewis lung carcinoma (LLC) cells with a new photosensitizer, mono-L-aspartyl chlorin e6 (NP...

journal_title：International journal of cancer

authors： Usuda J,Okunaka T,Furukawa K,Tsuchida T,Kuroiwa Y,Ohe Y,Saijo N,Nishio K,Konaka C,Kato H

更新日期：2001-08-15 00:00:00

abstract：:3-Nitrobenzanthrone (3-NBA) is an environmental pollutant and suspected human carcinogen found in emissions from diesel and gasoline engines and on the surface of ambient air particulate matter; human exposure to 3-NBA is likely to occur primarily via the respiratory tract. In our study female Sprague Dawley rats were...

journal_title：International journal of cancer

authors： Bieler CA,Cornelius MG,Klein R,Arlt VM,Wiessler M,Phillips DH,Schmeiser HH

更新日期：2005-10-10 00:00:00

abstract：:We have examined, in proliferating neoplastic cells, the effect on DNA of EGTA (a chelator of Ca2+) and W7 (an inhibitor of calmodulin). The treatment results in release of single-stranded DNA fragments (2-10 kb) from pre-labelled HMW DNA. When DNA from synchronized neoplastic cells in S phase is examined, almost all ...

journal_title：International journal of cancer

authors： Lönn U,Lönn S

更新日期：1986-06-15 00:00:00

abstract：:HER2 is an erbB/HER type 1 tyrosine kinase receptor that is frequently over-expressed in malignant epithelial tumours. Herceptin, a humanised mouse monoclonal antibody to HER2, is proven therapeutically in the management of metastatic breast cancer, significantly prolonging survival when combined with cytotoxic chemot...

journal_title：International journal of cancer

authors： Cox G,Vyberg M,Melgaard B,Askaa J,Oster A,O'Byrne KJ

更新日期：2001-05-15 00:00:00