Abstract：
:Noroviruses belong to a genus of genetically diverse viruses within the family Caliciviridae and cause acute gastroenteritis in humans and animals. They are subdivided into genogroups, each of which further segregates into genotypes. Until recently, a new genotype was based on a defined pairwise distance cutoff of complete VP1 sequences, but with the increasing number of available norovirus sequences, this cutoff is no longer accurate, and sequences in the public database have been misclassified. In this paper, we demonstrate that the pairwise distance cutoff method can no longer be used and outline a phylogenetic approach to classify noroviruses. Furthermore, we propose a dual nomenclature using both ORF1 and VP1 sequences, as recombination is common and recognizing recombinant viruses may be relevant. With the continuing emergence of new norovirus lineages, we propose to coordinate nomenclature of new norovirus genotypes through an international norovirus working group.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Kroneman A,Vega E,Vennema H,Vinjé J,White PA,Hansman G,Green K,Martella V,Katayama K,Koopmans Mdoi
10.1007/s00705-013-1708-5subject
Has Abstractpub_date
2013-10-01 00:00:00pages
2059-68issue
10eissn
0304-8608issn
1432-8798journal_volume
158pub_type
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