Abstract:
INTRODUCTION:Phentolamine mesylate has been reported to be an effective local anesthetic reversal agent for soft tissue but has not been studied regarding reversal of pulpal anesthesia. The authors conducted a prospective randomized, single-blind study comparing the reversal of pulpal and soft tissue anesthesia when phentolamine was administered at 30 minutes versus 60 minutes after the administration of an inferior alveolar nerve (IAN) block. METHODS:Ninety adult subjects received 2 sets of injections consisting of an IAN block followed by an injection of phentolamine at 30 minutes and a sham injection at 60 minutes or a sham injection given at 30 minutes and a phentolamine injection given at 60 minutes in 2 separate appointments. The authors used an electric pulp tester to test the first and second molars, premolars, and incisors for pulpal anesthesia in 4-minute cycles for 120 minutes. Lip and tongue soft tissue anesthesia was also monitored. RESULTS:Phentolamine significantly (P < .05) reduced duration of both pulpal and soft tissue anesthesia when administered at either 30 or 60 minutes after an IAN block. CONCLUSIONS:Phentolamine would be beneficial for patients who would like to experience a faster return to normal soft tissue function and sensation after the administration of local anesthesia. However, because pulpal anesthesia is also reversed fairly rapidly, phentolamine should be administered at the end of the dental appointment.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Elmore S,Nusstein J,Drum M,Reader A,Beck M,Fowler Sdoi
10.1016/j.joen.2012.12.024subject
Has Abstractpub_date
2013-04-01 00:00:00pages
429-34issue
4eissn
0099-2399issn
1878-3554pii
S0099-2399(13)00013-7journal_volume
39pub_type
杂志文章,随机对照试验abstract::The current external inflammatory root resorption treatment protocol, which uses calcium hydroxide dressing, usually comprises multiple and long-term applications. In addition to the need for multiple appointments for calcium hydroxide replacement, the long-term maintenance of this compound in the root canal weakens d...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2015.03.019
更新日期:2015-09-01 00:00:00
abstract::The antimicrobial effect of RC-Prep and its components--10% urea peroxide, 15% EDTA, and glycol--were evaluated individually, in vitro, within dentinal tubules. Standardized bovine incisor root specimens that had been infected with either Staphylococcus aureus or Streptococcus peltzer were incubated with each agent fo...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/S0099-2399(99)80296-9
更新日期:1999-12-01 00:00:00
abstract:INTRODUCTION:The aims of this study were to examine the immunolocalization of protein phosphatase 1 (PP1) in developing mouse pulp tissue and to explore the role of PP1 in odontoblastic differentiation and in vitro angiogenesis in human dental pulp cells (HDPCs). METHODS:Immunolocalization of PP1 was assessed in devel...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2016.10.013
更新日期:2017-03-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of different irrigating solutions on smear layer removal and dentinal tubule opening on root canal surfaces after post space preparation and to study whether additional ultrasonic irrigation has any effect on smear layer removal. Forty-eight anterior teeth were trea...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2009.01.006
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:Revascularization treatment is rapidly becoming an accepted treatment alternative for the management of endodontic pathology in immature permanent teeth with necrotic dental pulps. However, the success and timing of clinical resolution of symptoms, and radiographic outcomes of interest, such as continued h...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2014.08.023
更新日期:2014-12-01 00:00:00
abstract::A degree of uncertainty exists about the use of cotton pellets in the pulp chamber after canal obturation. The purpose of this study was to poll practicing endodontists and generalists regarding their preference. Forty-six endodontists and an equal number of general dentists were polled in a mail survey regarding thei...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1097/00004770-200209000-00007
更新日期:2002-09-01 00:00:00
abstract::The dislocation resistance of root fillings created with MetaSEAL, a self-adhesive 4-META-containing methacrylate resin-based sealer, was evaluated. Forty-six incisors were cleaned and shaped using NaOCl and EDTA as irrigants. They were filled with gutta-percha/MetaSEAL or gutta-percha/AH Plus sealer using either a si...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2008.03.028
更新日期:2008-07-01 00:00:00
abstract::Immune and nervous systems play key roles in periapical pathosis; however, their spatial associations, which may be a prerequisite for paracrine interactions in the progression of periapical lesions, remain to be examined. In this study we examined the distribution and frequency of spatial associations between major h...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2006.08.014
更新日期:2007-02-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to verify the expression of the calcium-sensing receptor (CaSR) and its role in mineral trioxide aggregate (MTA)-induced odontoblastic differentiation and mineralization in human dental pulp cells (hDPCs). METHODS:The expression of CaSR in human dental pulp tissue and hDPCs w...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2019.03.019
更新日期:2019-07-01 00:00:00
abstract:INTRODUCTION:The purpose of this systematic review was to compare the clinical and radiographic outcomes of nonsurgical retreatment with those of endodontic surgery to determine which modality offers more favorable outcomes. METHODS:The study began with targeted electronic searches of MEDLINE, PubMed, and Cochrane dat...
journal_title:Journal of endodontics
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.joen.2009.04.023
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:Teeth undergoing initial endodontic therapy have a very high survival rate. Some teeth that continue to show signs of pathosis after the initial therapy will require nonsurgical (orthograde) retreatment. Outcome assessment of endodontic retreatment is crucial for appropriate case selection and treatment pl...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2010.02.009
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:Buffered local anesthetics have not been studied for incision and drainage procedures in dentistry. The purpose of this prospective, randomized, double-blind study was to compare the pain of infiltration and pain of an incision and drainage procedure by using a buffered versus a nonbuffered 2% lidocaine wi...
journal_title:Journal of endodontics
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.joen.2013.07.008
更新日期:2013-11-01 00:00:00
abstract::The purpose of this study was to evaluate the durability of insulated probes designed to be used with the Endocater Apex Locator when put through multiple cleaning and autoclaving cycles. The manufacturer has reported that the plastic coating on the probes is reliable with normal use and sterilizable up to a maximum o...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/S0099-2399(06)81502-5
更新日期:1993-08-01 00:00:00
abstract:INTRODUCTION:The aim was to assess the association of inducible costimulator (ICOS) and ICOS ligand with bone destruction in apical periodontitis (AP). METHODS:Specimens from patients presenting with AP were obtained during apicoectomy and subjected to histopathologic analysis and molecular assessment of ICOS/ICOS lig...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2019.03.018
更新日期:2019-07-01 00:00:00
abstract::In the past, measurement of microleakage has been based on measurement of dye or radioactive isotope penetration. A method has been developed to allow electronic monitoring of microflow in the same specimen over a period of time. This method was used to compare previously reported retrograde materials with an amalgam/...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/S0099-2399(06)80072-5
更新日期:1994-11-01 00:00:00
abstract::The aim of this study was to investigate the cytotoxic and nitric oxide (NO)-inducing effects of bismuth oxide (Bi(2)O(3))-containing Portland cement (BPC) on human dental pulp cells. We also assessed whether heme oxygenase-1 (HO-1) is involved in BPC-induced cytotoxicity in dental pulp cells. Cytotoxicity and NO prod...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2007.07.012
更新日期:2007-11-01 00:00:00
abstract::Mineral trioxide aggregate (MTA) is being advocated for vital pulp therapy. In the case of direct pulp capping, hemorrhage control is an important step on success, but little is known about the effect of MTA on pulpal bleeding. In addition, there has been a lack of information on the effect of MTA on smooth muscle con...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2007.03.007
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to compare the efficacy of conventional syringe, ultrasonic, EndoVac (Discus Dental, Culver City, CA), and Self-Adjusting File (SAF) (Re-Dent-Nova, Ra'nana, Israel) irrigation systems in removing calcium hydroxide (Ca[OH]2) from simulated root canal irregularities. METHODS:The ro...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2013.10.019
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Warm vertically compacted gutta-percha obturation techniques use root canal sealers that are heated during the obturation. This study aims at investigating the suitability of selected sealers with warm gutta-percha obturation techniques. METHODS:The composition of an experimental sealer (Septodont; Saint ...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2014.06.007
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:A ferrule on anterior endodontic-treated teeth has been evaluated using clinical trials, in vitro tests, and finite element analysis (FEA). The patient-specific FEA with a nonuniform ferrule and nonlinear contact biting load associated with clinical validation can be used to predict failure. METHODS:A pat...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2017.04.024
更新日期:2017-09-01 00:00:00
abstract::Microbial control--fundamental to healing of apical periodontitis--is central to endodontic practice. The effectiveness of antibacterial measures is generally monitored (in clinical research studies) by microbiological root canal sampling (MRS), which is often used as a predictor for healing. This article addresses th...
journal_title:Journal of endodontics
pub_type: 杂志文章,评审
doi:10.1016/j.joen.2006.11.006
更新日期:2007-03-01 00:00:00
abstract:INTRODUCTION:More information regarding the ability of single files to maintain the original canal position is required before adopting a single-file approach to cleaning and shaping. This study compares apical transportation in curved root canals when instrumenting with a single WaveOne (WO) file (Dentsply Tulsa Denta...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2013.09.021
更新日期:2014-05-01 00:00:00
abstract::Ten extracted human maxillary first molars were selected with a variety of root curvatures. The distofacial roots were resected and the mesiofacial canals were instrumented to a size #25 K file. Three techniques were used to introduce Ca(OH)2 paste into the instrumented canals. These techniques were evaluated for thei...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/s0099-2399(06)81220-3
更新日期:1992-08-01 00:00:00
abstract::Patients with odontogenic cutaneous sinus tracts usually seek treatment from a physician instead of a dentist and the etiology is frequently misdiagnosed. This case report describes a patient who sought treatment from a dentist because of a history of a previous cutaneous swelling on the ipsilateral side of his cheek....
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/s0099-2399(06)80959-3
更新日期:1992-06-01 00:00:00
abstract:INTRODUCTION:Experimental studies show that dental pulp cells respond unfavorably to contact with resin composite restorative material. Hypothetically, in a random population, the frequency of apical periodontitis should be higher for teeth restored with resin composite than with amalgam. Therefore, the aim was to comp...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2014.05.002
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:This clinical study was conducted to compare the levels of endotoxins (lipopolysaccharides [LPSs]) found in primary and secondary endodontic infections with apical periodontitis by correlating LPS contents with clinical/radiographic findings. In addition, the presence of target gram-negative anaerobic bact...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2012.04.021
更新日期:2012-08-01 00:00:00
abstract::Mineral Trioxide Aggregate (MTA) has been shown in a number of experiments to be a potential root-end filling material. The purpose of this study was to examine the periradicular tissue response of monkeys to MTA and amalgam as root-end fillings. The pulps were removed from all the maxillary incisors of three monkeys....
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/S0099-2399(97)80051-9
更新日期:1997-04-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to compare the accuracy of the Root ZX II Apex Locator (RZX), the Elements Apex Locator (ELE), and the Precision Apex Locator (PAL). METHODS:Forty single-rooted extracted teeth were decoronated and the root canals coronally flared. Actual canal lengths were determined by inse...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2009.09.016
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to evaluate and compare, clinically and radiographically, the effects of platelet-rich fibrin (PRF) and mineral trioxide aggregate (MTA) as pulpotomy agents in permanent teeth with incomplete root development. METHODS:A total number of 70 children requiring pulpotomy in 70 pe...
journal_title:Journal of endodontics
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.joen.2014.01.009
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:An ideal root canal sealer creates a bacteria-resistant seal and exhibits antimicrobial activity, biocompatibility, and osteoconductivity. The aim of this study was to assess the effects of 3 root canal sealers on cell viability, inflammatory response, and osteogenic potential in MC3T3-E1 cells. METHODS:A...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2018.09.006
更新日期:2019-01-01 00:00:00