Small animal positron emission tomography imaging and in vivo studies of atherosclerosis.

Abstract:

:Atherosclerosis is a growing health challenge globally, and despite our knowledge of the disease has increased over the last couple of decades, many unanswered questions remain. As molecular imaging can be used to visualize, characterize and measure biological processes at the molecular and cellular levels in living systems, this technology represents an opportunity to investigate some of these questions in vivo. In addition, molecular imaging may be translated into clinical use and eventually pave the way for more personalized treatment regimes in patients. Here, we review the current knowledge obtained from in vivo positron emission tomography studies of atherosclerosis performed in small animals.

authors

Hag AM,Ripa RS,Pedersen SF,Bodholdt RP,Kjaer A

doi

10.1111/cpf.12017

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

173-85

issue

3

eissn

1475-0961

issn

1475-097X

journal_volume

33

pub_type

杂志文章,评审
  • Disturbed glucose metabolism is associated with left ventricular dysfunction using tissue Doppler imaging in patients with myocardial infarction.

    abstract:AIMS:To investigate the association between glucose abnormalities and left ventricular (LV) function assessed by tissue Doppler imaging (TDI) in patients with previous history of myocardial infarction and without known diabetes mellitus. PATIENTS AND METHODS:In a cross-sectional study, 123 patients, aged 31-80 years, ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2007.00717.x

    authors: Henareh L,Lind B,Brodin LA,Agewall S

    更新日期:2007-01-01 00:00:00

  • Hemodynamic response to resistance exercise with and without blood flow restriction in healthy subjects.

    abstract:PURPOSE:To compare the hemodynamic response during resistance exercise at high intensity (HI), low intensity (LI) and low intensity with blood flow restriction (LI-BFR) in healthy subjects. METHODS:Twelve men performed three sets of unilateral knee extension exercises at LI-BFR and LI (15 repetitions; 20% of 1RM) and ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/cpf.12218

    authors: Poton R,Polito MD

    更新日期:2016-05-01 00:00:00

  • Telemetry-derived heart rate variability responses to a physical stressor.

    abstract::Analysis of heart rate variability (HRV) responses to an orthostatic challenge can be used to investigate autonomic control of heart rate, an index of cardiovascular function. HRV is typically assessed using the electrocardiogram (ECG), which can be impractical for use with large population-based studies. PURPOSE:To ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12320

    authors: Montaño A,Brown F,Credeur DP,Williams MA,Stoner L

    更新日期:2017-07-01 00:00:00

  • Does postexercise modelled capillary blood flow accurately reflect cardiovascular effects by different exercise intensities?

    abstract::Blood flow (BF) in exercising muscles is an important factor for exercise capacity. Recently, a non-invasive method to estimate capillary BF (Qcap ) was introduced. Using this method, the Fick principle is re-arranged by using relative differences in deoxygenated haemoglobin (ΔHHb) as a surrogate for arteriovenous O2 ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12434

    authors: Stöcker F,Von Oldershausen C,Paternoster FK,Schulz T,Oberhoffer R

    更新日期:2018-05-01 00:00:00

  • Relationship between plasma volume and essential blood constituents in patients with heart failure and preserved ejection fraction.

    abstract:INTRODUCTION:Notwithstanding recent progress on molecular mechanisms underlying heart failure with preserved ejection fraction (HFpEF), multiple pathophysiological aspects of this condition including the basis of anaemia and other haematological disorders remain unresolved. In this study, we sought to determine the rel...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12614

    authors: Diaz-Canestro C,Haider T,Lundby C,Montero D

    更新日期:2020-03-01 00:00:00

  • Effects of different periods of hypoxic training on glucose metabolism and insulin sensitivity.

    abstract::This study examined the effects of different periods of hypoxic training on glucose metabolism. Sedentary subjects underwent hypoxic training (FiO2 = 15.0%) for either 2 weeks (2-week group; n = 11) or 4 weeks (4-week group; n = 10). The 2-week group conducted training sessions on 6 days week(-1) for 2 weeks, whereas ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/cpf.12133

    authors: Morishima T,Hasegawa Y,Sasaki H,Kurihara T,Hamaoka T,Goto K

    更新日期:2015-03-01 00:00:00

  • The effects of unilateral transcutaneous electrical nerve stimulation of the median nerve on bilateral somatosensory thresholds.

    abstract::Transcutaneous electrical nerve stimulation (TENS) is used to relieve acute and chronic pain. TENS electrodes are applied at the site of pain or in segments related to the pain, although there is limited research to support either approach. This study investigated the effects of unilateral TENS on mechanical and therm...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2006.00689.x

    authors: Dean J,Bowsher D,Johnson MI

    更新日期:2006-09-01 00:00:00

  • Appendicular lean mass and site-specific muscle loss in the extremities correlate with dynamic strength.

    abstract:BACKGROUND:Previous studies have reported the non-homogenous loss of muscle mass (site-specific muscle loss) with ageing, but this relationship to the loss of strength is not totally understood. PURPOSE:To investigate the relationship between maximal dynamic strength and site-specific muscle mass of the thigh and uppe...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12292

    authors: Thiebaud RS,Loenneke JP,Abe T,Fahs CA,Rossow LM,Kim D,Beck TW,Bemben DA,Larson RD,Bemben MG

    更新日期:2017-05-01 00:00:00

  • Vascular ultrasound for monitoring of inflammatory activity in Takayasu arteritis.

    abstract:BACKGROUND:Takayasu arteritis (TA) is a rare large-vessel arteritis that primarily affects the aorta and its major branches. The aim of this study was to describe the value of high frequency ultrasound for monitoring of inflammatory activity. METHODS:Twenty-five patients, range 11-71 years, diagnosed with TA were inve...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12601

    authors: Svensson C,Eriksson P,Zachrisson H

    更新日期:2020-01-01 00:00:00

  • Contractile properties of knee-extensors in one single family with nemaline myopathy: central and peripheral aspects of muscle activation.

    abstract::Patients with nemaline myopathy, a muscle disorder primarily affecting the thin filaments, suffer from weakness which is poorly understood. As disturbed excitation-contraction coupling has been suggested as a possible mechanism, the present study was designed to investigate whether the contractile properties of the kn...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2007.00740.x

    authors: Gerrits K,Pauw-Gommans I,van Engelen B,de Haan A

    更新日期:2007-07-01 00:00:00

  • An assessment of pulmonary function testing and ventilatory kinematics by optoelectronic plethysmography.

    abstract::New advances in computer processing and imaging have allowed the development of innovative techniques to assess lung function. A promising methodology is optoelectronic plethysmography (OEP). OEP evaluates ventilatory kinematics through the use of infrared imaging. Markers are placed, and images read on the chest, bac...

    journal_title:Clinical physiology and functional imaging

    pub_type: 历史文章,杂志文章,评审

    doi:10.1111/j.1475-097X.2011.01028.x

    authors: Layton AM,Garber CE,Basner RC,Bartels MN

    更新日期:2011-09-01 00:00:00

  • Echocardiography in Fabry disease: diagnostic value of endocardial border binary appearance.

    abstract:BACKGROUND AND AIM:It has been reported that the endocardium in Fabry disease has a binary appearance on transthoracic echocardiography. It has been suggested that this sign could be used with good accuracy to differentiate Fabry disease from hypertrophic cardiomyopathy and even as a first filter to screen for suspecte...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2008.00851.x

    authors: Koskenvuo JW,Engblom E,Kantola IM,Hartiala JJ,Saraste A,Kiviniemi TO,Mononen I,Saraste M

    更新日期:2009-05-01 00:00:00

  • Fixed ratio or lower limit of normal for the FEV1 /VC ratio: relation to symptoms and extended lung function tests.

    abstract::There is no general agreement on the spirometric definition of chronic obstructive pulmonary disease (COPD). The global initiative for obstructive lung disease recommends a fixed ratio between forced expiratory volume in one-second (FEV1 ) and forced vital capacity (FVC) of <0·7 (FR) for the diagnosis of COPD. Europea...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12294

    authors: Wollmer P,Frantz S,Engström G,Dencker M,Löfdahl CG,Nihlén U

    更新日期:2017-05-01 00:00:00

  • Effect of exercise intensity on oxygen consumption kinetics in non-exercising muscle during exercise.

    abstract::This study examined the effect of exercise intensity on the kinetics of muscle oxygen consumption in non-exercising forearm flexor muscles (VO(2mf)) during exercise. Seven healthy male subjects performed cycling exercise for 60 min at 30% of maximal oxygen consumption (%VO(2max)) and 30 min at 50% VO(2max) on separate...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1475-097X.2011.01073.x

    authors: Nagasawa T

    更新日期:2012-05-01 00:00:00

  • Seven-site versus three-site method of body composition using BodyMetrix ultrasound compared to dual-energy X-ray absorptiometry.

    abstract::Obesity is a steadily growing epidemic affecting all segments of the population including college-aged students. The weight gain that is evidenced amid the transitional stage of college years increases the risks associated with cardiovascular and metabolic diseases. The BodyMetrix® BX-2000 (ULTRA) using a seven-site m...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12307

    authors: Baranauskas MN,Johnson KE,Juvancic-Heltzel JA,Kappler RM,Richardson L,Jamieson S,Otterstetter R

    更新日期:2017-05-01 00:00:00

  • The association between muscle EMG and perfusion in knee extensor muscles.

    abstract::The relationships between electromyographic (EMG) activity and force as well as muscle blood flow and work have been well established. However, the association between muscle blood flow and EMG activity remains unsolved. Thus, to test the hypothesis that muscle EMG activity relates to muscle perfusion in different com...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2006.00656.x

    authors: Laaksonen MS,Kyröläinen H,Kalliokoski KK,Nuutila P,Knuuti J

    更新日期:2006-03-01 00:00:00

  • Gender variability in electromyographic activity, in vivo behaviour of the human gastrocnemius and mechanical capacity during the take-off phase of a countermovement jump.

    abstract:PURPOSE:The purpose of this study was to analyse gender differences in neuromuscular behaviour of the gastrocnemius and vastus lateralis during the take-off phase of a countermovement jump (CMJ), using direct measures (ground reaction forces, muscle activity and dynamic ultrasound). METHODS:Sixty-four young adults (ag...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12369

    authors: Rubio-Arias JÁ,Ramos-Campo DJ,Peña Amaro J,Esteban P,Mendizábal S,Jiménez JF

    更新日期:2017-11-01 00:00:00

  • Neurovascular responses to sequential deep inspirations assessed via laser-Doppler perfusion changes in dorsal finger skin.

    abstract::A vasomotor reflex triggered by a rapid and deep inspiration causes arteriolar vasoconstriction and a transient decrease in skin blood flow in most people. This is the inspiratory gasp vascular response (IGVR). The most common site of its measurement has been on the palmar or plantar aspect of the digits and little is...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1046/j.1475-097x.2002.00404.x

    authors: Mayrovitz HN,Groseclose EE

    更新日期:2002-01-01 00:00:00

  • Impact of gender on echocardiographic characteristics in heart transplant recipients.

    abstract:AIMS:Assessment following heart transplantation (HTx) is routinely performed using transthoracic echocardiography. Differences in long-term mortality following HTx related to donor-recipient matching have been reported, but effects of gender on cardiac size and function are not well studied. The aims of this study were...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12565

    authors: Ingvarsson A,Werther-Evaldsson A,Smith GJ,Waktare J,Nilsson J,Stagmo M,Roijer A,Rådegran G,Meurling C

    更新日期:2019-07-01 00:00:00

  • Comparison between magnetic resonance imaging and B-mode ultrasound in detecting and estimating the extent of human carotid atherosclerosis.

    abstract:BACKGROUND:In MRI studies of carotid plaques, ultrasound is used to find plaques, which are later imaged using MRI. The performance in plaque detection has not been compared between the modalities. The aim of the current study was to compare the performance of MRI and ultrasound in detecting carotid artery plaques and ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12415

    authors: Hjelmgren O,Schmidt C,Johansson L,Bergström GML

    更新日期:2018-03-01 00:00:00

  • Clinical applications of diffusion-weighted magnetic resonance imaging in diagnosis of renal lesions - a systematic review.

    abstract::Diffusion-weighted magnetic resonance imaging (DW-MRI) is an established technique to detect the changes of the diffusion of water in biological tissues and reflect the pathophysiological process on the molecular level. It is a promising non-invasive imaging modality in detection of microstructural and functional chan...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,评审

    doi:10.1111/cpf.12313

    authors: Ye J,Kumar BS,Li XB,Li HM,Zhou YW,Liu LQ

    更新日期:2017-09-01 00:00:00

  • Effects of a Ginkgo biloba extract on forearm haemodynamics in healthy volunteers.

    abstract::The aim was to validate possible vasodilating effects of a Ginkgo biloba extract with a secondary aim of finding a pharmacodynamic signal relating to the active component of these extracts. We studied the effect of G. biloba extract on forearm haemodynamics in 16 healthy subjects (nine females, seven males) with a med...

    journal_title:Clinical physiology and functional imaging

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1475-097x.2002.00445.x

    authors: Mehlsen J,Drabaek H,Wiinberg N,Winther K

    更新日期:2002-11-01 00:00:00

  • Use of temperature alterations to characterize vascular reactivity.

    abstract::Monitoring alterations in fingertip temperature during ischaemia and the subsequent hyperaemia provides a novel way of studying microvascular reactivity. The relations between parameters characterizing blood perfusion and the thermal response of fingertips were studied using experimental and theoretical approaches. Du...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2010.00981.x

    authors: Ley O,Dhindsa M,Sommerlad SM,Barnes JN,Devan AE,Naghavi M,Tanaka H

    更新日期:2011-01-01 00:00:00

  • Intramuscular water movement during and after isometric muscle contraction: evaluation at different exercise intensities.

    abstract::We aimed at evaluating the effect of isometric muscle contraction on intramuscular water movement at different exercise intensities. Seven men performed 1-min isometric ankle dorsiflexion (20% and 50% maximal voluntary contractions [MVCs]) with a non-magnetic custom-made dynamometer, inside a magnetic resonance (MR) d...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12239

    authors: Yanagisawa O,Kurihara T

    更新日期:2016-09-01 00:00:00

  • Differences between smooth pursuit and optokinetic eye movements using limited lifetime dot stimulation: a functional magnetic resonance imaging study.

    abstract::In this study, we examined possible differences in brain activation between smooth pursuit and optokinetic reflexive (OKR) eye movements using functional magnetic resonance imaging (fMRI). Eighteen healthy subjects performed two different eye movement paradigms. In the first paradigm, smooth pursuit eye movements were...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2009.00858.x

    authors: Schraa-Tam CK,van der Lugt A,Smits M,Frens MA,van Broekhoven PC,van der Geest JN

    更新日期:2009-07-01 00:00:00

  • Haemostatic and inflammatory responses to blood flow-restricted exercise in patients with ischaemic heart disease: a pilot study.

    abstract::Low-intensity resistance exercise can effectively induce muscle hypertrophy and increases in strength when combined with moderate blood flow restriction (BFR). As this type of exercise does not require lifting heavy weights, it might be a feasible method of cardiac rehabilitation, in which resistance exercise has been...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1475-097X.2012.01158.x

    authors: Madarame H,Kurano M,Fukumura K,Fukuda T,Nakajima T

    更新日期:2013-01-01 00:00:00

  • Three-dimensional echocardiography to identify right ventricular dilatation in patients with corrected Fallot anomaly or pulmonary stenosis.

    abstract:BACKGROUND:3-Dimensional Echocardiography allows measuring volumes and parameters of myocardial deformation (strain). Myocardial strain has been suggested to be superior to conventional echo parameters in the assessment of right ventricular (RV) function. Myocardial strain can be assessed by cardiac magnetic resonance ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/cpf.12665

    authors: Trzebiatowska-Krzynska A,Swahn E,Wallby L,Nielsen NE,Carlhäll CJ,Engvall J

    更新日期:2021-01-01 00:00:00

  • Long-term changes in dynamic cerebral autoregulation: a 10 years follow up study.

    abstract::This study takes a novel approach to describing time-related changes in dynamic cerebral autoregulation (dCA). It is well-recognized that dCA exhibits both intra- and inter- subject variability, and this study seeks to characterize the extent to which intra-subject variability occurs after a significant period of time...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2009.00880.x

    authors: Brodie FG,Panerai RB,Foster S,Evans DH,Robinson TG

    更新日期:2009-09-01 00:00:00

  • Validity and interobserver agreement of lower extremity local tissue water measurements in healthy women using tissue dielectric constant.

    abstract:BACKGROUND:Tissue dielectric constant (TDC) measurement may become an important tool in the clinical evaluation of chronic lower extremity swelling in women; however, several factors are known to influence TDC measurements, and comparative data on healthy lower extremities are few. METHODS:Thirty-four healthy women vo...

    journal_title:Clinical physiology and functional imaging

    pub_type: 杂志文章

    doi:10.1111/j.1475-097X.2012.01129.x

    authors: Jensen MR,Birkballe S,Nørregaard S,Karlsmark T

    更新日期:2012-07-01 00:00:00

  • Arterial concentration of 99mTc-sestamibi at rest, during peak exercise and after dipyridamole infusion.

    abstract::Tracers for myocardial perfusion imaging during stress should not only have high cardiac uptake but they should also have a fast blood clearance to prevent myocardial tracer uptake after the ischaemic stimulus. The present study characterize the early phase of the arterial (99m)Tc-sestamibi (MIBI) time-activity curve ...

    journal_title:Clinical physiology and functional imaging

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1475-097X.2004.00570.x

    authors: Sand NP,Juelsgaard P,Rasmussen K,Flø C,Thuesen L,Bagger JP,Nielsen TT,Rehling M

    更新日期:2004-11-01 00:00:00