Abstract:
:Atherosclerosis is a growing health challenge globally, and despite our knowledge of the disease has increased over the last couple of decades, many unanswered questions remain. As molecular imaging can be used to visualize, characterize and measure biological processes at the molecular and cellular levels in living systems, this technology represents an opportunity to investigate some of these questions in vivo. In addition, molecular imaging may be translated into clinical use and eventually pave the way for more personalized treatment regimes in patients. Here, we review the current knowledge obtained from in vivo positron emission tomography studies of atherosclerosis performed in small animals.
journal_name
Clin Physiol Funct Imagingjournal_title
Clinical physiology and functional imagingauthors
Hag AM,Ripa RS,Pedersen SF,Bodholdt RP,Kjaer Adoi
10.1111/cpf.12017subject
Has Abstractpub_date
2013-05-01 00:00:00pages
173-85issue
3eissn
1475-0961issn
1475-097Xjournal_volume
33pub_type
杂志文章,评审abstract:AIMS:To investigate the association between glucose abnormalities and left ventricular (LV) function assessed by tissue Doppler imaging (TDI) in patients with previous history of myocardial infarction and without known diabetes mellitus. PATIENTS AND METHODS:In a cross-sectional study, 123 patients, aged 31-80 years, ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2007.00717.x
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To compare the hemodynamic response during resistance exercise at high intensity (HI), low intensity (LI) and low intensity with blood flow restriction (LI-BFR) in healthy subjects. METHODS:Twelve men performed three sets of unilateral knee extension exercises at LI-BFR and LI (15 repetitions; 20% of 1RM) and ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,随机对照试验
doi:10.1111/cpf.12218
更新日期:2016-05-01 00:00:00
abstract::Analysis of heart rate variability (HRV) responses to an orthostatic challenge can be used to investigate autonomic control of heart rate, an index of cardiovascular function. HRV is typically assessed using the electrocardiogram (ECG), which can be impractical for use with large population-based studies. PURPOSE:To ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12320
更新日期:2017-07-01 00:00:00
abstract::Blood flow (BF) in exercising muscles is an important factor for exercise capacity. Recently, a non-invasive method to estimate capillary BF (Qcap ) was introduced. Using this method, the Fick principle is re-arranged by using relative differences in deoxygenated haemoglobin (ΔHHb) as a surrogate for arteriovenous O2 ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12434
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION:Notwithstanding recent progress on molecular mechanisms underlying heart failure with preserved ejection fraction (HFpEF), multiple pathophysiological aspects of this condition including the basis of anaemia and other haematological disorders remain unresolved. In this study, we sought to determine the rel...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12614
更新日期:2020-03-01 00:00:00
abstract::This study examined the effects of different periods of hypoxic training on glucose metabolism. Sedentary subjects underwent hypoxic training (FiO2 = 15.0%) for either 2 weeks (2-week group; n = 11) or 4 weeks (4-week group; n = 10). The 2-week group conducted training sessions on 6 days week(-1) for 2 weeks, whereas ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,随机对照试验
doi:10.1111/cpf.12133
更新日期:2015-03-01 00:00:00
abstract::Transcutaneous electrical nerve stimulation (TENS) is used to relieve acute and chronic pain. TENS electrodes are applied at the site of pain or in segments related to the pain, although there is limited research to support either approach. This study investigated the effects of unilateral TENS on mechanical and therm...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2006.00689.x
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Previous studies have reported the non-homogenous loss of muscle mass (site-specific muscle loss) with ageing, but this relationship to the loss of strength is not totally understood. PURPOSE:To investigate the relationship between maximal dynamic strength and site-specific muscle mass of the thigh and uppe...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12292
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Takayasu arteritis (TA) is a rare large-vessel arteritis that primarily affects the aorta and its major branches. The aim of this study was to describe the value of high frequency ultrasound for monitoring of inflammatory activity. METHODS:Twenty-five patients, range 11-71 years, diagnosed with TA were inve...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12601
更新日期:2020-01-01 00:00:00
abstract::Patients with nemaline myopathy, a muscle disorder primarily affecting the thin filaments, suffer from weakness which is poorly understood. As disturbed excitation-contraction coupling has been suggested as a possible mechanism, the present study was designed to investigate whether the contractile properties of the kn...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2007.00740.x
更新日期:2007-07-01 00:00:00
abstract::New advances in computer processing and imaging have allowed the development of innovative techniques to assess lung function. A promising methodology is optoelectronic plethysmography (OEP). OEP evaluates ventilatory kinematics through the use of infrared imaging. Markers are placed, and images read on the chest, bac...
journal_title:Clinical physiology and functional imaging
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1475-097X.2011.01028.x
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND AND AIM:It has been reported that the endocardium in Fabry disease has a binary appearance on transthoracic echocardiography. It has been suggested that this sign could be used with good accuracy to differentiate Fabry disease from hypertrophic cardiomyopathy and even as a first filter to screen for suspecte...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2008.00851.x
更新日期:2009-05-01 00:00:00
abstract::There is no general agreement on the spirometric definition of chronic obstructive pulmonary disease (COPD). The global initiative for obstructive lung disease recommends a fixed ratio between forced expiratory volume in one-second (FEV1 ) and forced vital capacity (FVC) of <0·7 (FR) for the diagnosis of COPD. Europea...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12294
更新日期:2017-05-01 00:00:00
abstract::This study examined the effect of exercise intensity on the kinetics of muscle oxygen consumption in non-exercising forearm flexor muscles (VO(2mf)) during exercise. Seven healthy male subjects performed cycling exercise for 60 min at 30% of maximal oxygen consumption (%VO(2max)) and 30 min at 50% VO(2max) on separate...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1475-097X.2011.01073.x
更新日期:2012-05-01 00:00:00
abstract::Obesity is a steadily growing epidemic affecting all segments of the population including college-aged students. The weight gain that is evidenced amid the transitional stage of college years increases the risks associated with cardiovascular and metabolic diseases. The BodyMetrix® BX-2000 (ULTRA) using a seven-site m...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12307
更新日期:2017-05-01 00:00:00
abstract::The relationships between electromyographic (EMG) activity and force as well as muscle blood flow and work have been well established. However, the association between muscle blood flow and EMG activity remains unsolved. Thus, to test the hypothesis that muscle EMG activity relates to muscle perfusion in different com...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2006.00656.x
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:The purpose of this study was to analyse gender differences in neuromuscular behaviour of the gastrocnemius and vastus lateralis during the take-off phase of a countermovement jump (CMJ), using direct measures (ground reaction forces, muscle activity and dynamic ultrasound). METHODS:Sixty-four young adults (ag...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12369
更新日期:2017-11-01 00:00:00
abstract::A vasomotor reflex triggered by a rapid and deep inspiration causes arteriolar vasoconstriction and a transient decrease in skin blood flow in most people. This is the inspiratory gasp vascular response (IGVR). The most common site of its measurement has been on the palmar or plantar aspect of the digits and little is...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1046/j.1475-097x.2002.00404.x
更新日期:2002-01-01 00:00:00
abstract:AIMS:Assessment following heart transplantation (HTx) is routinely performed using transthoracic echocardiography. Differences in long-term mortality following HTx related to donor-recipient matching have been reported, but effects of gender on cardiac size and function are not well studied. The aims of this study were...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12565
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:In MRI studies of carotid plaques, ultrasound is used to find plaques, which are later imaged using MRI. The performance in plaque detection has not been compared between the modalities. The aim of the current study was to compare the performance of MRI and ultrasound in detecting carotid artery plaques and ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12415
更新日期:2018-03-01 00:00:00
abstract::Diffusion-weighted magnetic resonance imaging (DW-MRI) is an established technique to detect the changes of the diffusion of water in biological tissues and reflect the pathophysiological process on the molecular level. It is a promising non-invasive imaging modality in detection of microstructural and functional chan...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,评审
doi:10.1111/cpf.12313
更新日期:2017-09-01 00:00:00
abstract::The aim was to validate possible vasodilating effects of a Ginkgo biloba extract with a secondary aim of finding a pharmacodynamic signal relating to the active component of these extracts. We studied the effect of G. biloba extract on forearm haemodynamics in 16 healthy subjects (nine females, seven males) with a med...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1475-097x.2002.00445.x
更新日期:2002-11-01 00:00:00
abstract::Monitoring alterations in fingertip temperature during ischaemia and the subsequent hyperaemia provides a novel way of studying microvascular reactivity. The relations between parameters characterizing blood perfusion and the thermal response of fingertips were studied using experimental and theoretical approaches. Du...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2010.00981.x
更新日期:2011-01-01 00:00:00
abstract::We aimed at evaluating the effect of isometric muscle contraction on intramuscular water movement at different exercise intensities. Seven men performed 1-min isometric ankle dorsiflexion (20% and 50% maximal voluntary contractions [MVCs]) with a non-magnetic custom-made dynamometer, inside a magnetic resonance (MR) d...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12239
更新日期:2016-09-01 00:00:00
abstract::In this study, we examined possible differences in brain activation between smooth pursuit and optokinetic reflexive (OKR) eye movements using functional magnetic resonance imaging (fMRI). Eighteen healthy subjects performed two different eye movement paradigms. In the first paradigm, smooth pursuit eye movements were...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2009.00858.x
更新日期:2009-07-01 00:00:00
abstract::Low-intensity resistance exercise can effectively induce muscle hypertrophy and increases in strength when combined with moderate blood flow restriction (BFR). As this type of exercise does not require lifting heavy weights, it might be a feasible method of cardiac rehabilitation, in which resistance exercise has been...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1475-097X.2012.01158.x
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:3-Dimensional Echocardiography allows measuring volumes and parameters of myocardial deformation (strain). Myocardial strain has been suggested to be superior to conventional echo parameters in the assessment of right ventricular (RV) function. Myocardial strain can be assessed by cardiac magnetic resonance ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12665
更新日期:2021-01-01 00:00:00
abstract::This study takes a novel approach to describing time-related changes in dynamic cerebral autoregulation (dCA). It is well-recognized that dCA exhibits both intra- and inter- subject variability, and this study seeks to characterize the extent to which intra-subject variability occurs after a significant period of time...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2009.00880.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Tissue dielectric constant (TDC) measurement may become an important tool in the clinical evaluation of chronic lower extremity swelling in women; however, several factors are known to influence TDC measurements, and comparative data on healthy lower extremities are few. METHODS:Thirty-four healthy women vo...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2012.01129.x
更新日期:2012-07-01 00:00:00
abstract::Tracers for myocardial perfusion imaging during stress should not only have high cardiac uptake but they should also have a fast blood clearance to prevent myocardial tracer uptake after the ischaemic stimulus. The present study characterize the early phase of the arterial (99m)Tc-sestamibi (MIBI) time-activity curve ...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章
doi:10.1111/j.1475-097X.2004.00570.x
更新日期:2004-11-01 00:00:00