Abstract:
:Verbal irony conveys various emotional messages, from criticism to humor, that differ from the meaning of the actual words. To understand irony, we need conceptual knowledge of irony in addition to an understanding of context. We investigated the neural mechanism of irony comprehension, focusing on two overlooked issues: conceptual knowledge and emotional response. We studied 35 healthy subjects who underwent functional MRI. During the scan, the subject examined first-person-view stories describing verbal interactions, some of which included irony directed toward the subject. After MRI, the subject viewed the stories again and rated the degree of irony, humor, and negative emotion evoked by the statements. We identified several key findings about irony comprehension: (1) the right anterior superior temporal gyrus may be responsible for representing social conceptual knowledge of irony, (2) activation in the medial prefrontal cortex and the right anterior inferior temporal gyrus might underlie the understanding of context, (3) modulation of activity in the right amygdala, hippocampus, and parahippocampal gyrus is associated with the degree of irony perceived, and (4) modulation of activity in the right dorsolateral prefrontal cortex varies with the degree of humor perceived. Our results clarified the differential contributions of the neural loci of irony comprehension, enriching our understanding of pragmatic language communication from a social behavior point of view.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Akimoto Y,Sugiura M,Yomogida Y,Miyauchi CM,Miyazawa S,Kawashima Rdoi
10.1002/hbm.22242subject
Has Abstractpub_date
2014-04-01 00:00:00pages
1167-78issue
4eissn
1065-9471issn
1097-0193journal_volume
35pub_type
杂志文章abstract::Transcranial magnetic stimulation (TMS) during positron emission tomography (PET) is a novel technique for in vivo measurements of connectivity and excitability of the human cerebral cortex. Here we describe tools that allow investigators to position the stimulating coil over a target region and to verify the actual p...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:
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abstract::Mind wandering (MW) has become a prominent topic of neuroscientific investigation due to the importance of understanding attentional processes in our day-to-day experiences. Emerging evidence suggests a critical role for three large-scale brain networks in MW: the default network (DN), the central executive network (C...
journal_title:Human brain mapping
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abstract:OBJECTIVES:Memory impairment is one of the most prominent cognitive deficits in temporal lobe epilepsy (TLE). The overall goal of this study was to explore the contribution of cortical and hippocampal (subfield) damage to impairment of auditory immediate recall (AIMrecall), auditory delayed recall (ADMrecall), and audi...
journal_title:Human brain mapping
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doi:10.1002/hbm.21226
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journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
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更新日期:2017-04-01 00:00:00
abstract::We describe a method for the statistical parametric mapping of low resolution electromagnetic tomography (LORETA) using high-density electroencephalography (EEG) and individual magnetic resonance images (MRI) to investigate the characteristics of the mismatch negativity (MMN) generators in schizophrenia. LORETA, using...
journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23366
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20636
更新日期:2009-05-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22249
更新日期:2014-04-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23473
更新日期:2017-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23458
更新日期:2017-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20388
更新日期:2008-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24679
更新日期:2019-09-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25273
更新日期:2020-11-24 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22178
更新日期:2014-01-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24536
更新日期:2019-06-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24026
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:To analyze functional connectivity (FC) of the visual cortex using resting-state functional MRI in human primary open-angle glaucoma (POAG) patients. MATERIALS AND METHODS:Twenty-two patients with known POAG and 22 age-matched controls were included in this IRB-approved study. Subjects were evaluated by 3 T MR...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22079
更新日期:2013-10-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22002
更新日期:2013-07-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21396
更新日期:2012-11-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23904
更新日期:2018-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.24314
更新日期:2018-12-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.23059
更新日期:2016-02-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22560
更新日期:2014-11-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20747
更新日期:2009-10-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
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journal_title:Human brain mapping
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