Th1- and Th2-like subsets of innate lymphoid cells.

Abstract:

:Innate lymphoid cells (ILCs) constitute a family of effectors in innate immunity and regulators of tissue remodeling that have a cytokine and transcription factor expression pattern that parallels that of the T-helper (Th) cell family. Here, we discuss how ILCs can be categorized and summarize the current knowledge of Th1- and Th2-like ILCs with regard to the molecular mechanisms of development, effector functions, and their interplay with other cell types.

journal_name

Immunol Rev

journal_title

Immunological reviews

authors

Bernink J,Mjösberg J,Spits H

doi

10.1111/imr.12034

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

133-8

issue

1

eissn

0105-2896

issn

1600-065X

journal_volume

252

pub_type

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