Abstract:
:The analysis of deep sequencing data allows for a genome-wide overview of all the small RNA molecules (the 'sRNome') that are present in a single organism. In the present paper, we review the processing of CRISPR (clustered regularly interspaced short palindromic repeats) RNA, C/D box sRNA (small non-coding RNA) and tRNA in Nanoarchaeum equitans. The minimal and fragmented genome of this tiny archaeon permits a sequencing depth that enables the identification of processing intermediates in the study of RNA processing pathways. These intermediates include circular C/D box sRNA molecules and tRNA half precursors.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Richter H,Mohr S,Randau Ldoi
10.1042/BST20120276subject
Has Abstractpub_date
2013-02-01 00:00:00pages
411-5issue
1eissn
0300-5127issn
1470-8752pii
BST20120276journal_volume
41pub_type
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