当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > Induction of liver GST transcriptions by tert-butylhydroquinone reduced microcystin-LR accumulation in Nile tilapia (Oreochromis niloticus).

Induction of liver GST transcriptions by tert-butylhydroquinone reduced microcystin-LR accumulation in Nile tilapia (Oreochromis niloticus).

Abstract：

:The cyanobacterial toxin, MC-LR, is predominantly presented during toxic cyanobacterial blooms and is consumed by phytoplanktivorous fish and zooplanktivorous fish directly. Detoxification of MC-LR in liver was believed to begin with conjugate formation with GSH, catalyzed by GSTs. MC-LR GSH conjugates display increased solubility and are subjected to accelerated biliary excretion. In this study, we showed that the mRNA transcriptions of GSTA, GPX and UCP2 were increased within 8h following MC-LR exposure in isolated hepatocytes of Nile tilapia, confirming the roles of phase II enzymes, especially GSTs, in MC-LR detoxification in tilapia. The widely used food-additive, synthetic antioxidant, tert-butylhydroquinone (tBHQ) has been shown to induce phase II enzymes including GSTs, via the antioxidant responsive elements (ARE) locate in the regulatory regions of these genes. Our results also showed that the transcription of various GSTs, including GSTA, GSTR2 and GSTT were significantly induced by tBHQ in Nile tilapia. In consistence, fish fed on tBHQ-containing diet (0.01 percent tBHQ) showed significantly reduced MC-LR accumulation in liver tissues 48 h after an oral administration of a single dose of 250 μg MC-LR/kg body weight (bwt). The findings in this research suggested that tBHQ could reduce MC-LR accumulations in liver, likely through the induction of phase II metabolizing enzymes such as GSTs. Subacute effects of tBHQ and its potential applications in fishery need to be further investigated.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

He S,Liang XF,Sun J,Shen D

doi

10.1016/j.ecoenv.2012.12.021

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

128-35

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(12)00482-4

journal_volume

90

pub_type

杂志文章

相关文献

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY文献大全
  • Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid.

    abstract：:The ecotoxicity of the nonsteroidal anti-inflammatory drugs (NSAIDs) diclofenac, ibuprofen, naproxen, and acetylsalicylic acid (ASA) has been evaluated using acute Daphnia and algal tests. Toxicities were relatively low, with half-maximal effective concentration (EC50) values obtained using Daphnia in the range from 6...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/S0147-6513(03)00141-6

    authors： Cleuvers M

    更新日期：2004-11-01 00:00:00

  • The H295R system for evaluation of endocrine-disrupting effects.

    abstract：:The present studies were undertaken to evaluate the utility of the H295R system as an in vitro assay to assess the potential of chemicals to modulate steroidogenesis. The effects of four model chemicals on the expression of ten steroidogenic genes and on the production of three steroid hormones were examined. Exposure...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2006.06.012

    authors： Gracia T,Hilscherova K,Jones PD,Newsted JL,Zhang X,Hecker M,Higley EB,Sanderson JT,Yu RM,Wu RS,Giesy JP

    更新日期：2006-11-01 00:00:00

  • Microarray analysis of di-n-butyl phthalate and 17α ethinyl-oestradiol responses in three-spined stickleback testes reveals novel candidate genes for endocrine disruption.

    abstract：:Phthalate esters are plasticizers frequently found in wastewater effluents. Previous studies on phthalates have reported anti-androgenic activity in mammals, causing concerns of their potential effects on the reproduction of aquatic organisms. Another group of environmental endocrine disrupters, steroidal estrogens, a...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.09.039

    authors： Prokkola JM,Katsiadaki I,Sebire M,Elphinstone-Davis J,Pausio S,Nikinmaa M,Leder EH

    更新日期：2016-02-01 00:00:00

  • Genomic DNA methylation signatures in different tissues after ambient air particulate matter exposure.

    abstract：:DNA methylation (5-mc) is one of the several epigenetic markers, and is generally associated with the inhibition of gene expression. Both hyper and hypo DNA methylation are associated with the diseases. Exposure to fine particles with a diameter of 2.5 μm or less (PM2.5) is a pervasive risk factor for cardiopulmonary ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.04.049

    authors： Li Z,Li N,Guo C,Li X,Qian Y,Wu J,Yang Y,Wei Y

    更新日期：2019-09-15 00:00:00

  • Influence of pathogenic fungi on the life history and predation rate of mites attacking a psyllid pest.

    abstract：:The two biological control agents, predatory mite Amblydromalus limonicus Garman & McGregor (Acari: Phytoseiidae) and entomopathogenic fungi (EPF) Beauveria bassiana (Balsamo) Vuillemin (Hypocreales: Cordycipitaceae), have the potential to independently suppress the invasive tomato potato psyllid (TPP), Bactericera co...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.109585

    authors： Liu JF,Zhang ZQ,Beggs JR,Wei XY

    更新日期：2019-11-15 00:00:00

  • Ammonium tolerance and toxicity of Actinoscirpus grossus--a candidate species for use in tropical constructed wetland systems.

    abstract：:Actinoscirpus grossus, a native species in tropical wetlands of South-East Asia, North Australia and the Pacific islands, has been reported to perform well in experimental scale constructed wetland (CW) systems. However, little is known about how high NH4(+) concentrations prevailing in wastewater affect growth and pe...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.05.032

    authors： Piwpuan N,Jampeetong A,Brix H

    更新日期：2014-09-01 00:00:00

  • Environmental status of (micro)plastics contamination in Portugal.

    abstract：:Plastics and microplastics are ubiquitous contaminants in aquatic ecosystems. This critical review is the first attempt at analyzing sources, concentration, impacts and solutions of (micro)plastic litter in Portugal based on all currently available literature. We found that, besides sea-based sources (e.g. shipping, f...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章,评审

    doi：10.1016/j.ecoenv.2020.110753

    authors： Prata JC,da Costa JP,Lopes I,Duarte AC,Rocha-Santos T

    更新日期：2020-09-01 00:00:00

  • Improved grain yield and lowered arsenic accumulation in rice plants by inoculation with arsenite-oxidizing Achromobacter xylosoxidans GD03.

    abstract：:Arsenite is the predominant arsenic species in flooded paddy soil, and arsenite bioaccumulation in rice grains has been identified as a major problem in many Asian countries. Lowering arsenite level in rice plants and grain via accelerating arsenite oxidation is a potential strategy to help populations, who depended o...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111229

    authors： Wang K,Li Y,Wu Y,Qiu Z,Ding Z,Wang X,Chen W,Wang R,Fu F,Rensing C,Yang G

    更新日期：2020-12-15 00:00:00

  • Larval development ratio test with the calanoid copepod Acartia tonsa as a new bioassay to assess marine sediment quality.

    abstract：:The copepod Acartia tonsa was used as a model species to assess marine sediment quality. Acute and chronic bioassays, such as larval development ratio (LDR) and different end-points were evaluated. As a pelagic species, A. tonsa is mainly exposed to water-soluble toxicants and bioassays are commonly performed in seawa...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.10.062

    authors： Buttino I,Vitiello V,Macchia S,Scuderi A,Pellegrini D

    更新日期：2018-03-01 00:00:00

  • Copper induces hepatocyte autophagy via the mammalian targets of the rapamycin signaling pathway in mice.

    abstract：:Although copper is among the indispensable trace elements in animal physiological processes, it exerts toxicity upon over-exposure. The present study aimed to investigate hepatocyte autophagy induced by CuSO4 and its potential mechanism. A total of 240 ICR mice (four-week-old, 120 males and 120 females) were randomly ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111656

    authors： Liu H,Deng H,Cui H,Jian Z,Guo H,Fang J,Zuo Z,Deng J,Li Y,Wang X,Zhao L

    更新日期：2021-01-15 00:00:00

  • In vitro and in silico AHR assays for assessing the risk of heavy oil-derived polycyclic aromatic hydrocarbons in fish.

    abstract：:In the aftermath of the Great East Japan Earthquake of March 11, 2011, marine fish in Kesennuma Bay, Japan, have been contaminated with heavy oil containing polycyclic aromatic hydrocarbons (PAHs). To estimate the risk of six PAHs (benzo[α]pyrene, dibenzothiophene, phenanthrene, 2,3,5-trimethylnaphthalene, acenaphthen...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.06.008

    authors： Bak SM,Nakata H,Koh DH,Yoo J,Iwata H,Kim EY

    更新日期：2019-10-15 00:00:00

  • Genotoxic effects and serum abnormalities in residents of regions proximal to e-waste disposal facilities in Jinghai, China.

    abstract：:Electronic waste (e-waste) disposal is a growing problem in China, and its effects on human health are a concern. To determine the concentrations of pollutants in peripheral blood and genetic aberrations near an e-waste disposal area in Jinghai, China, blood samples were collected from 30 (age: 41±11.01 years) and 28 ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.03.034

    authors： Li K,Liu S,Yang Q,Zhao Y,Zuo J,Li R,Jing Y,He X,Qiu X,Li G,Zhu T

    更新日期：2014-07-01 00:00:00

  • Copper-induced changes in tissue enzyme activity in a freshwater mussel.

    abstract：:Changes in enzyme activity levels are of great diagnostic value. Lysosomal membrane is often the target of injury by xenobiotics, resulting in destabilization. Variations in the activity of acid phosphatase (ACP) a marker enzyme, in gills and hepatopancreas of the freshwater mussel Lamellidens corrianus (Lea) exposed ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2005.01.003

    authors： Rajalakshmi S,Mohandas A

    更新日期：2005-09-01 00:00:00

  • Acute toxicity of multi-walled carbon nanotubes, sodium pentachlorophenate, and their complex on earthworm Eisenia fetida.

    abstract：:Laboratory experiments were undertaken to relate biomarker responses to the toxicities of multi-walled carbon nanotubes (MWCNTs) and sodium pentachlorophenate (PCP-Na), both individually and combined. The acute toxicities of MWCNTs and PCP-Na on earthworm Eisenia fetida were studied through different exposure methods ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2014.01.041

    authors： Zhang L,Hu C,Wang W,Ji F,Cui Y,Li M

    更新日期：2014-05-01 00:00:00

  • Impact of wastewater treatment plant discharge on enzyme activity in freshwater sediments.

    abstract：:The biological self-purification processes are a central point for the ecological states of rivers. The degradation efficiency of pollutants is mainly due to the microflora and can be detected with enzyme-activity tests. Extracellular-enzyme activity of freshwater sediments was measured, in a microcosm, versus differe...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1998.1656

    authors： Montuelle B,Volat B

    更新日期：1998-05-01 00:00:00

  • Carbofuran promotes biochemical changes in carp exposed to rice field and laboratory conditions.

    abstract：:Effects of carbofuran commercial formulation on oxidative stress parameters were studied in carps (Cyprinus carpio) exposed to 50µg/L for 7 and 30 days under rice field and laboratory conditions. Thiobarbituric acid reactive substance (TBARS) levels were increased in the brain of fish after 7 and 30 days under rice fi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2013.12.012

    authors： Clasen B,Leitemperger J,Murussi C,Pretto A,Menezes C,Dalabona F,Marchezan E,Adaime MB,Zanella R,Loro VL

    更新日期：2014-03-01 00:00:00

  • Effects of NiO inhalation on alveolar macrophages and the humoral immune systems of rats.

    abstract：:To study the effects of inhaled NiO particles on alveolar macrophages and the humoral immune system, male Wistar rats were continuously exposed to NiO aerosols for 4 weeks and 4 months, respectively. Fractions of alveolar macrophages, granulocytes, and lymphocytes in lung lavages, number of polynucleated macrophages, ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(84)90011-3

    authors： Spiegelberg T,Kördel W,Hochrainer D

    更新日期：1984-12-01 00:00:00

  • Effects of CO2 restriction on growth of Nitzschia closterium: Evidence from stable isotopes and fatty acids.

    abstract：:Algae blooms frequently occur in the coastal areas of China, and pose numbers of adverse effects to marine environment. Nitzschia closterium is one of the algal species associated with algae blooms and was selected as the target algae of this work. This study was the first attempt to investigate the effect of carbon s...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.03.110

    authors： Lou Y,Liu Y,Wang H,Li N,Liu Q,Liu Y,Zhao X

    更新日期：2019-08-15 00:00:00

  • Ecotoxicity of arsenic contamination toward the soil enchytraeid Enchytraeus crypticus at different biological levels: Laboratory studies.

    abstract：:The ecotoxicity of arsenic (As) contamination toward small soil fauna living in soil pore water such as soil enchytraeids has rarely been studied but is important in the assessment of soil pollution. Here, the endpoints of As ecotoxicity to Enchytraeus crypticus were studied at three biological levels, i.e., individua...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111218

    authors： Li S,Jia M,Li Z,Ke X,Wu L,Christie P

    更新日期：2021-01-01 00:00:00

  • A comparative study on pesticide formulations for application in running waters.

    abstract：:Release rates into water of monolinuron, desmetryne, and carbofuran from three different types of formulations have been studied to control aquatic weeds in running waters. The migration of active ingredients (AI) from conventional wettable powder formulations was complete within 1 day, while the migration from ethyle...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(85)90066-1

    authors： Bahadir M,Pfister G

    更新日期：1985-10-01 00:00:00

  • Using 2003-2014 U.S. NHANES data to determine the associations between per- and polyfluoroalkyl substances and cholesterol: Trend and implications.

    abstract：:Exposure to per- and polyfluoroalkyl substances (PFASs) is a major concern due to their widespread occurrence and adverse health outcomes. The possible binding of PFASs to peroxisome proliferator-activated receptors (PPARs) and nuclear receptors raises concerns that PFASs may impact cholesterol levels in human. In thi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.02.061

    authors： Dong Z,Wang H,Yu YY,Li YB,Naidu R,Liu Y

    更新日期：2019-05-30 00:00:00

  • Impacts of Pantoea agglomerans strain and cation-modified clay minerals on the adsorption and biodegradation of phenanthrene.

    abstract：:Interactions between microorganisms and minerals have the potential contribution to remove polycyclic aromatic hydrocarbons (PAHs) in model systems. In this study, phenanthrene (PHE) was used as a probe molecule to explore the potential adsorption and biotransformation processes in the presence of microorganisms and v...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.05.091

    authors： Tao K,Zhao S,Gao P,Wang L,Jia H

    更新日期：2018-10-01 00:00:00

  • Oxidative stress, neurotoxicity, and metallothionein (MT) gene expression in juvenile rock fish Sebastes schlegelii under the different levels of dietary chromium (Cr(6+)) exposure.

    abstract：:Juvenile Sebastes schlegelii were exposed for 4 weeks with the different levels of dietary chromium (Cr(6+)) concentration (0, 30, 60, 120 and 200mg/kg). The superoxide dismutase (SOD) activity, glutathione S-transferase (GST) activity, and glutathione (GSH) level of liver and gill were evaluated after 4 weeks exposur...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.12.001

    authors： Kim JH,Kang JC

    更新日期：2016-03-01 00:00:00

  • Potential risk assessment in stream sediments, soils and waters after remediation in an abandoned W>Sn mine (NE Portugal).

    abstract：:The mining complex of Murçós belongs to the Terras de Cavaleiros Geopark, located in Trás-os-Montes region, northeast Portugal. A stockwork of NW-SE-trending W>Sn quartz veins intruded Silurian metamorphic rocks and a Variscan biotite granite. The mineralized veins contain mainly quartz, cassiterite, wolframite, schee...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.06.045

    authors： Antunes IM,Gomes ME,Neiva AM,Carvalho PC,Santos AC

    更新日期：2016-11-01 00:00:00

  • Fluoride contamination in groundwater sources in Southwestern Nigeria: Assessment using multivariate statistical approach and human health risk.

    abstract：:The present study investigated the ionic and fluoride concentrations in tap water and its associated health risk to local dwellers of Ogun State (Abeokuta south), Nigeria. 63 samples were collected from twenty-one different locations. Results obtained revealed the mean concentration of fluoride (F-) as 1.23 mg/L. Othe...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.03.022

    authors： Emenike CP,Tenebe IT,Jarvis P

    更新日期：2018-07-30 00:00:00

  • Plant growth promotion and alleviation of salinity stress in Capsicum annuum L. by Bacillus isolated from saline soil in Xinjiang.

    abstract：:To maintain the growth and development of pepper in saline condition, candidates of plant growth promoting rhizobacteria (PGPR) were isolated, and detected to plant growth promoting (PGP) potential under salt stress was investigated. Thirteen bacterial strains with 1-aminocyclopropane-1-carboxylate (ACC) deaminase act...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.08.070

    authors： Wang W,Wu Z,He Y,Huang Y,Li X,Ye BC

    更新日期：2018-11-30 00:00:00

  • Short-term exposure to sublethal tebuconazole induces physiological impairment in male zebrafish (Danio rerio).

    abstract：:The aim of the present study was to assess the physiological response of male zebrafish Danio rerio to the fungicide tebuconazole and recovery in fungicide-free water. Acute toxicity tests were carried out and the median lethal concentration (LC(50)) from 24 to 96 h was calculated. The fish were exposed to a sublethal...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2009.09.020

    authors： Sancho E,Villarroel MJ,Fernández C,Andreu E,Ferrando MD

    更新日期：2010-03-01 00:00:00

  • Immunotoxicity of nickel: Pathological and toxicological effects.

    abstract：:Nickel (Ni) is a widely distributed metal in the environment and an important pollutant because of its many industrial applications. With increasing incidences of Ni contamination, Ni toxicity has become a global public health concern and recent evidence suggests that Ni adversely affects the immune system. Hence, thi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章,评审

    doi：10.1016/j.ecoenv.2020.111006

    authors： Guo H,Liu H,Jian Z,Cui H,Fang J,Zuo Z,Deng J,Li Y,Wang X,Zhao L,He R,Tang H

    更新日期：2020-10-15 00:00:00

  • Heavy metals in human urine, foods and drinking water from an e-waste dismantling area: Identification of exposure sources and metal-induced health risk.

    abstract：:Electronic waste or e-waste dismantling activities are known to release metals. However, the human exposure pathways of metals, and their association with oxidative stress in e-waste dismantling areas (EDAs) remain unclear. In this study, our results revealed elevated geometric mean concentrations in vegetables (Cd 0....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.10.039

    authors： Zhang T,Ruan J,Zhang B,Lu S,Gao C,Huang L,Bai X,Xie L,Gui M,Qiu RL

    更新日期：2019-03-01 00:00:00

  • Bioassay-derived androgenic and estrogenic activity in municipal sewage in Australia and New Zealand.

    abstract：:Raw sewage and sewage at various stages of treatment were sampled from 15 municipal sewage treatment plants in south Queensland (Australia) and Canterbury (New Zealand). Estrogenic and androgenic activities were determined with sheep estrogen receptor and rainbow trout androgen receptor binding assays, respectively. S...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2005.07.020

    authors： Leusch FD,Chapman HF,van den Heuvel MR,Tan BL,Gooneratne SR,Tremblay LA

    更新日期：2006-11-01 00:00:00