Abstract：
:Rapid eye movement (REM) sleep behavior disorder (RBD) occurring prior to age 50 is termed early-onset RBD. Early-onset RBD comprises a substantial minority of cases, and demonstrates the differences in demographics, comorbidities, and clinical considerations from previously described typical RBD with onset >50years. The world literature on RBD is reviewed with specific focus on features that distinguish early-onset RBD, including more gender parity, increased proportion of idiopathic cases, increased proportion of cases associated with narcolepsy, parasomnia overlap disorder, antidepressants, and possibly autoimmune disorders, and clinical presentation.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Ju YEdoi
10.1016/j.sleep.2012.09.026subject
Has Abstractpub_date
2013-08-01 00:00:00pages
768-74issue
8eissn
1389-9457issn
1878-5506pii
S1389-9457(12)00392-9journal_volume
14pub_type
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