Abstract:
OBJECTIVE:This study aimed to investigate the effect of SagaPro, a product derived from Angelica archangelica leaf, on nocturia. MATERIAL AND METHODS:Sixty-nine male patients 45 years or older with at least two nocturnal voids were randomized to receive SagaPro or placebo in a double-blind design for 8 weeks. Voiding diaries were assessed before and after the treatment. RESULTS:The results indicate that SagaPro is safe. The actual number of nocturnal voids (ANV), nocturnal polyuria index (NPi) and nocturnal bladder capacity index (NBC index) decreased in the test population, but there was no significant difference between the treatment groups. Subsequent subgroup analysis showed that SagaPro significantly reduced the NBC index and nocturnal voids per sleeping hour in comparison to the placebo in participants with baseline NBC index above 1.3. When participants with sleep disorders were excluded from this group, ANV was also significantly reduced for the SagaPro group in comparison to the placebo group. CONCLUSION:SagaPro, made from an extract of the medicinal herb Angelica archangelica, is safe. This study did not show that SagaPro improved nocturia overall compared to placebo. Subgroup analysis suggested a beneficial effect in individuals with decreased nocturnal bladder capacity, which warrants further study.
journal_name
Scand J Uroljournal_title
Scandinavian journal of urologyauthors
Sigurdsson S,Geirsson G,Gudmundsdottir H,Egilsdottir PB,Gudbjarnason Sdoi
10.3109/00365599.2012.695390subject
Has Abstractpub_date
2013-02-01 00:00:00pages
26-32issue
1eissn
2168-1805issn
2168-1813journal_volume
47pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To investigate whether health-related quality of life (HRQoL) depends on psychosocial factors, rather than on factors related to the cancer treatment, this study explored the associations between HRQoL, personality, choice of coping and clinical parameters in surgically treated renal cell carcinoma (RCC) pati...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2014.990051
更新日期:2015-01-01 00:00:00
abstract::Objective: To translate and cross-culturally adapt the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) into Danish and assess the reliability of the translated version. Methods: The NIH-CPSI was translated into Danish by a formalized translation procedure. Study participants suffering from C...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2019.1591501
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to establish 15-year postprostatectomy prostate cancer-specific mortality (PCSM), explore the time to prostate-specific antigen (PSA) relapse and identify clinically available prognostic factors. MATERIAL AND METHODS:From 1987 to 2004, 309 men (median age 62 years, range 40-74 yea...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2013.817483
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Bladder pain syndrome/interstitial cystitis (BPS/IC) includes a heterogeneous collection of underlying pathological conditions. Compared to the classic IC with a Hunner lesion, now denominated ESSIC type 3C, the non-Hunner type of BPS/IC appears different in a number of respects. In a previous study, measurin...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/00365599.2012.699100
更新日期:2013-02-01 00:00:00
abstract::Prostate-sparing techniques have been advocated to improved functional outcomes after radical cystoprostatectomy (RCP) for invasive bladder cancer, but this may endanger the oncological outcome. This review addresses the current status of risk factors of prostate cancer (PCa) recurrence in patients with incidental PCa...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,评审
doi:10.3109/00365599.2012.723045
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the diagnostic accuracy of UBC® Rapid - a urine-based marker for bladder cancer - in patients with bladder cancer and controls, and to compare the test results across risk groups. MATERIALS AND METHODS:This prospective phase II study was conducted at four Swedish hospit...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1080/21681805.2017.1313309
更新日期:2017-08-01 00:00:00
abstract::Objectives: A prospective observational trial to develop and gather validity evidence using Messick's framework for a simulator-based test in TURB. Methods: Forty-nine doctors were recruited from urology departments (Herlev/Gentofte University Hospital, Rigshospitalet Copenhagen University Hospital and Zealand Univers...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2019.1663921
更新日期:2019-10-01 00:00:00
abstract::Robot-assisted radical cystectomy (RARC) with intracorporeal orthotopic neobladder (ONB) can be recognized to be the supreme discipline in urological pelvic surgery. The utilization of RARC with intracorporeal urinary diversion (ICUD) has increased during the last 15 years. This increase is primarily noted for ICUD wi...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,评审
doi:10.1080/21681805.2019.1598486
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the sleep quality and the association between sleep quality and quality of life in people with ileal conduit. MATERIALS AND METHODS:A descriptive and cross-sectional design was adopted. The study sample comprised 111 people with ileal conduit operated on in urology clin...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2016.1236834
更新日期:2016-12-01 00:00:00
abstract::Radical prostatectomy remains the gold-standard surgical treatment for clinically localized prostate cancer. Contrast imaging of the upper urinary tract is not part of the routine work-up of the patient before radical prostatectomy. This may lead to rare, albeit serious complications when anatomical anomalies are pres...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/00365599.2012.729222
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:To evaluate whether the presence of prostate atrophy (P.A.) in negative prostate biopsy is associated with prostate cancer (P.C.a) grade at surgical pathology among men who are ultimately diagnosed with P.C.a and undergo radical prostatectomy (R.P.). METHODS:A retrospective analysis was performed of 136 m...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2018.1551244
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:Urolithiasis is a common urological problem, and its incidence has been increasing worldwide, including in Japan. Relationships between stone etiology and rise in ambient temperature have been reported, but it remains unclear how age and gender affect these relationships. MATERIALS AND METHODS:A retrospectiv...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2016.1273969
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to report a therapeutic approach comprising a combination of debulking single-tract percutaneous nephrolithotomy (PCNL) and subsequent retrograde intrarenal surgery (RIRS) for treatment of staghorn stones in patients with solitary kidney. MATERIALS AND METHODS:A retrospective review...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2013.852621
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the severity and bother of lower urinary tract symptoms (LUTS) and evaluate the burden of each symptom in a male population. MATERIALS AND METHODS:Postal questionnaires were sent to 7470 men aged 30-80 years. The Danish Prostatic Symptom Score (DAN-PSS-1) was used to de...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2018.1505944
更新日期:2018-08-01 00:00:00
abstract::Purpose: It remains unclear whether patients with prostate cancer suspicion and negative magnetic resonance imaging (M.R.I.) can safely obviate biopsy. The purpose of this study was to assess the clinical negative predictive value (N.P.V.) of M.R.I. in excluding prostate cancer. The secondary end-point was to compare ...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2018.1551243
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyse the prevalence of osteoporosis and risk factors of osteoporotic fractures before androgen deprivation in Danish men. Treatment and prognosis of prostate cancer necessitate management of long-term consequences of androgen deprivation therapy (ADT), including accelerated bon...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2014.884160
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine employment outcomes after radiotherapy (RT) for prostate cancer (PCa). MATERIALS AND METHODS:The Danish DREAM database contains information about social benefits paid to Danish citizens. Data are recorded prospectively every week. From the database, it is possible to as...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2015.1119190
更新日期:2016-06-01 00:00:00
abstract::Objective: To analyze which factors in the history of a posterior urethral valve (PUV) patient relate to lower urinary tract symptoms (LUTS) in adulthood. This study also aimed to evaluate whether the patients have developed signs of a myogenic failure of detrusor. Materials and methods: LUTS were evaluated with a DAN...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2019.1596155
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to present early outcome data for patients treated for penile cancer with organ-sparing reconstructive surgery at two referral centres in Sweden. MATERIAL AND METHODS:Oncological, cosmetic and functional outcome and complications were analysed retrospectively during the period 2011-...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,多中心研究
doi:10.3109/21681805.2014.955822
更新日期:2015-04-01 00:00:00
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journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2015.1021832
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:This study evaluated the impact of hospital volume on local recurrence and distant metastasis in a population-based series of radical cystectomy patients in Sweden. MATERIAL AND METHODS:All patients who underwent cystectomy for bladder cancer in 1997-2002 in Sweden and were reported to the National Bladder C...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2013.787118
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to assess the prevalence of positive surgical margins (PSM) and urinary incontinence (UI) in relation to surgeons' annual radical prostatectomy (RP) volume. MATERIAL AND METHODS:This national study prospectively assessed 521 preoperatively continent patients with prostate cancer (PCa), sched...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,多中心研究
doi:10.3109/00365599.2012.707684
更新日期:2013-04-01 00:00:00
abstract:AIM:Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. MATERIAL AND METHODS:According to the Cancer Registry of Norway, 1,108 patients were diagnosed with T1 BC between 2008-2012. Information on surgical and m...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2020.1803401
更新日期:2020-08-12 00:00:00
abstract:OBJECTIVE:Patients with limited metastatic and locally advanced bladder cancer have a poor prognosis, and no definite treatment recommendations exist. However, long-term survival is possible for selected patients if surgery is combined with multiple courses of chemotherapy (i.e. induction chemotherapy). Patients with t...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2017.1321579
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:Positive surgical margins (PSMs) in men undergoing radical prostatectomy (RP) for prostate cancer are associated with an increased risk of biochemical recurrence. This study evaluated the long-term (>10 year) impact of PSMs on biochemical recurrence after RP in adjuvant treatment-naïve pT2-pT4 N0 men and dete...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2013.813067
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess stone-free rates following extracorporeal shockwave lithotripsy (ESWL) of pure calcium oxalate (CaOx) stones in the proximal ureter. MATERIAL AND METHODS:The investigators retrospectively examined 53 patients with 5-10 mm pure CaOx stones in the proximal ureter from the me...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/00365599.2012.711771
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:Nocturia may be characterized by indices derived from the frequency-volume chart (FVC). The objective of this study was to determine how these parameters relate to the severity of nocturia in men with and without lower urinary tract symptoms (LUTS). MATERIALS AND METHODS:A retrospective analysis of FVCs was ...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2014.973901
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:Reports from cancer registries often lack clinically relevant information, which would be useful in estimating the prognosis of individual patients with urothelial carcinoma of the urinary bladder (UCB). This article presents estimates of crude probabilities of death due to UCB and the expected loss of lifeti...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.1080/21681805.2016.1271354
更新日期:2017-02-01 00:00:00
abstract::Objective Finasteride 5 mg is a drug used to treat prostate hyperplasia. Little is known about its pattern of usage. This cross-national analysis of individual-level data from Denmark, Finland, Norway and Sweden was undertaken to appraise its usage and describe cross-national differences. Materials and methods Individ...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章
doi:10.3109/21681805.2015.1136676
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and safety of continuous saline bladder irrigation (CSBI) to a single immediate instillation of chemotherapy after transurethral resection of bladder tumor (TURBT) in patients with high grade primary non-muscle invasive bladder cancer (HG-NMIBC). MATERIALS AND METHODS:This study retro...
journal_title:Scandinavian journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1080/21681805.2018.1548502
更新日期:2018-01-01 00:00:00