The costs of disorders of the brain in Switzerland: an update from the European Brain Council Study for 2010.

Abstract:

BACKGROUND:In 2005, findings of the first "cost of disorders of the brain in Europe" study of the European Brain Council (EBC) showed that these costs cause a substantial economic burden to the Swiss society. In 2010 an improved update with a broader range of disorders has been analysed. This report shows the new findings for Switzerland and discusses changes. METHODS:Data are derived from the EBC 2010 census study that estimates 12-month prevalence of 12 groups of disorders of the brain and calculates costs (direct health-care costs, direct non-medical costs and indirect costs) by combining top-down and bottom up cost approaches using existing data. RESULTS:The most frequent disorder was headache (2.3 million). Anxiety disorders were found in 1 million persons and sleep disorders in 700,000 persons. Annual costs for all assessed disorders total to 14.5 billion Euro corresponding to about 1,900 EUR per inhabitant per year. Mood, psychotic disorders and dementias (appr. 2 billion EUR each) were most costly. Costs per person were highest for neurological/neurosurgery-relevant disorders, e.g. neuromuscular disorders, brain tumour and multiple sclerosis (38,000 to 24,000 EUR). CONCLUSION:The estimates of the EBC 2010 study for Switzerland provide a basis for health care planning. Increase in size and costs compared to 2005 are mostly due to the inclusion of new disorders (e.g., sleep disorders), or the re-definition of others (e.g., headache) and to an increase in younger cohorts. We suggest coordinated research and preventive measures coordinated between governmental bodies, private health-care and pharmaceutical companies.

journal_name

Swiss Med Wkly

journal_title

Swiss medical weekly

authors

Maercker A,Perkonigg A,Preisig M,Schaller K,Weller M,Cost of Disorders of the Brain in Europe Study Group.

doi

10.4414/smw.2013.13751

subject

Has Abstract

pub_date

2013-01-07 00:00:00

pages

w13751

eissn

1424-7860

issn

1424-3997

pii

smw-13751

journal_volume

143

pub_type

杂志文章
  • Ex utero intrapartum treatment (EXIT), a resuscitation option for intra-thoracic foetal pathologies.

    abstract::The ex utero intrapartum treatment (EXIT) procedure is designed to guarantee sufficient oxygenation for a foetus at risk of airway obstruction. This is achieved by improving lung ventilation, usually by establishing an airway during caesarean delivery whilst preserving the foetal-placental circulation temporarily. Ind...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2007/19/smw-11526

    authors: Kern C,Ange M,Morales,Peiry B,Pfister RE

    更新日期:2007-05-19 00:00:00

  • Anticoagulant treatment: the end of the old agents?

    abstract::New oral anticoagulants used as single target inhibitors of coagulation enzymes have been developed and tested in extensive trial programmes. Results of most of these trials showed non-inferior and/or superior efficacy and safety compared to standard treatment with LMWH or VKA. These results led to registration of the...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2012.13684

    authors: Graf L,Tsakiris DA

    更新日期:2012-10-01 00:00:00

  • Cost of attempted suicide: a retrospective study of extent and associated factors.

    abstract:QUESTIONS UNDER STUDY:Suicidal behaviour is a major source of burden of disease. While most studies focus on cost associated with completed suicides, data on costs of, non-lethal, suicide attempts are lacking. The aim of this study was to assess direct annual cost of suicide attempts in Basel in 2003 from a health serv...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,多中心研究

    doi:10.4414/smw.2012.13648

    authors: Czernin S,Vogel M,Flückiger M,Muheim F,Bourgnon JC,Reichelt M,Eichhorn M,Riecher-Rössler A,Stoppe G

    更新日期:2012-07-23 00:00:00

  • Termination of pregnancy in a border region between Switzerland and Italy (2008-2015).

    abstract::In Switzerland, voluntary termination of pregnancy (VTP) can be performed in all public and private hospitals with an obstetrics/gynaecology department. For various reasons, many Italian women use the Swiss healthcare system, in particular in Canton Ticino, a border region adjacent to Italy in the southern part of Swi...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2018.14636

    authors: Reinholz D,Casati S,Beretta O,Merlani G

    更新日期:2018-07-09 00:00:00

  • Changes in olfactory function with several pregnancies?

    abstract:OBJECTIVE:To investigate whether olfactory performance decreases as a function of the number of pregnancies, previous research having indicated that olfactory function decreases in the course of pregnancy. METHODS:In a prospective study three groups of women were investigated (total n = 93), women who have given birth...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/31/smw-12200

    authors: Wohlgemuth C,Beinder E,Ochsenbein-Kölble N,Hummel T

    更新日期:2008-08-09 00:00:00

  • Patients' understanding of blood tests and attitudes to HIV screening in the emergency department of a Swiss teaching hospital: a cross-sectional observational study.

    abstract:BACKGROUND:In Switzerland, patients may undergo "blood tests" without being informed what these are screening for. Inadequate doctor-patient communication may result in patient misunderstanding. We examined what patients in the emergency department (ED) believed they had been screened for and explored their attitudes t...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2015.14206

    authors: Favre-Bulle T,Baudat D,Darling KE,Mamin R,Peters S,Cavassini M,Hugli O

    更新日期:2015-12-04 00:00:00

  • Prognostic impact of plasma lipids in patients with lower respiratory tract infections - an observational study.

    abstract:PRINCIPLES:A decrease in plasma lipids occurs during severe sepsis and has prognostic implications in critical illness. Whether lipids have prognostic implications or could help to differentiate community-acquired pneumonia from other lower respiratory tract infections remains unknown. METHODS:We analysed data from pa...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12494

    authors: Gruber M,Christ-Crain M,Stolz D,Keller U,Müller C,Bingisser R,Tamm M,Mueller B,Schuetz P

    更新日期:2009-03-21 00:00:00

  • Genetic testing for glucokinase mutations in clinically selected patients with MODY: a worthwhile investment.

    abstract::The differential diagnosis for children with diabetes includes a group of monogenic diabetic disorders known as maturity-onset diabetes of the young (MODY). So far, six underlying gene defects have been identified. The most common subtypes are caused by mutations in the genes encoding the transcription factor HNF-1a (...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2005/23/smw-11030

    authors: Schnyder S,Mullis PE,Ellard S,Hattersley AT,Flück CE

    更新日期:2005-06-11 00:00:00

  • Posterior positional plagiocephaly treated with cranial remodeling orthosis.

    abstract:PRINCIPLES:Since the recommendation that infants sleep in the supine position, there has been an increase in cases of posterior positional plagiocephaly. Even though this condition is a purely cosmetic problem, if it is severe it may affect the child psychologically. Positioning may help in mild or moderate cases, but ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2007/25/smw-11702

    authors: de Ribaupierre S,Vernet O,Rilliet B,Cavin B,Kalina D,Leyvraz P-

    更新日期:2007-06-30 00:00:00

  • Effort-reward and work-life imbalance, general stress and burnout among employees of a large public hospital in Switzerland.

    abstract:INTRODUCTION:Effort-reward imbalance (ERI) and work-life imbalance (WLI) are recognised risk factors for work stress and burnout but have not been investigated conjointly so far and compared with each other in this regard. The present cross-sectional study provides initial evidence by studying associations of ERI and W...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2012.13577

    authors: Hämmig O,Brauchli R,Bauer GF

    更新日期:2012-05-31 00:00:00

  • Teamwork and clinician burnout in Swiss intensive care: the predictive role of workload, and demographic and unit characteristics.

    abstract:AIM:The levels of teamwork and clinician burnout in healthcare differ depending on demographic and unit characteristics. However, the impact of these characteristics varies between clinical settings. In addition, the impact of objectively measured workload in such settings is largely unknown. The aim of this study was ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2019.20033

    authors: Welp A,Rothen HU,Massarotto P,Manser T

    更新日期:2019-03-24 00:00:00

  • Insulin sensitivity in type 2 diabetes is closely associated with LDL particle size.

    abstract:PRINCIPLES:Small dense LDLs have been found to be associated with type 2 diabetes (T2DM). This association has been observed in the context of decreased HDL cholesterol and increased triglycerides. METHODS:In the present study the relationship between LDL particle size and insulin sensitivity was assessed in 46 patien...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/19/smw-12124

    authors: Krayenbuehl PA,Wiesli P,Schmid C,Lehmann R,Spinas GA,Berneis K

    更新日期:2008-05-03 00:00:00

  • Deficiencies in paediatric research applications delaying ethics committee approval.

    abstract:BACKGROUND:A clinical research application must be submitted for approval by a competent ethics committee (EC) before a study can be executed. There is very limited information on how such submissions could be optimised, especially regarding research in children and adolescents, which requires particular caution and ag...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20267

    authors: Bergstraesser E,Nadal D,Özgü H,Kleist P

    更新日期:2020-06-19 00:00:00

  • Heart failure clinic in a community hospital improves outcome in heart failure patients.

    abstract:PRINCIPLES:Heart failure is associated with a grim prognosis. Disease management programmes can improve prognosis in heart failure patients but the applicability to the general population remains limited. We aimed to compare the outcome, pharmacological therapy, and quality of life in unselected heart failure patients ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2006/17/smw-11274

    authors: Lainscak M,Keber I

    更新日期:2006-04-29 00:00:00

  • Congenital tuberculosis in a premature infant.

    abstract::Congenital tuberculosis was first suspected in a premature infant with patent ductus arteriosus (PDA), progressive respiratory distress and septic shock, when an enlarged mediastinal lymph node was noted intraoperatively at the time of PDA ligature. Culture revealed Mycobacterium tuberculosis. The asymptomatic mother ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2002/41/smw-10101

    authors: Stähelin-Massik J,Carrel T,Duppenthaler A,Zeilinger G,Gnehm HE

    更新日期:2002-11-23 00:00:00

  • Reactive hypoglycaemia due to late dumping syndrome: successful treatment with acarbose.

    abstract::Reactive hypoglycaemia is a rare disease which occurs postprandially in everyday life involving blood glucose levels below 2.5 to 2.8 mmol/l. We report on a 66-year-old patient who developed symptomatic reactive hypoglycaemia due to late dumping syndrome 10 years after oesophagectomy with cervical anastomosis. A 75 g ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2001/05/smw-09667

    authors: Imhof A,Schneemann M,Schaffner A,Brändle M

    更新日期:2001-02-10 00:00:00

  • Disseminated M. avium complex infection in the Swiss HIV Cohort Study: declining incidence, improved prognosis and discontinuation of maintenance therapy.

    abstract:BACKGROUND:Introduction of potent antiretroviral combination therapy (ART) has reduced overall morbidity and mortality amongst HIV-infected adults. Some prophylactic regimes against opportunistic infections can be discontinued in patients under successful ART. QUESTIONS UNDER STUDY:(1) The influence of the availabilit...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,多中心研究

    doi:2001/31/smw-09728

    authors: Rossi M,Flepp M,Telenti A,Schiffer V,Egloff N,Bucher H,Vernazza P,Bernasconi E,Weber R,Rickenbach M,Furrer H,Swiss HIV Cohort Study.

    更新日期:2001-08-11 00:00:00

  • Aortic distensibility alterations in adults with m.3243A>G MELAS gene mutation.

    abstract:PRINCIPLES:MELAS, or mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes is a new distinctive clinical entity. The current study was designed to assess ascending aortic elasticity in adult patients with MELAS syndrome and in gene carriers, and to compare the results with age- and gender-mat...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:smw-12390

    authors: Nemes A,Geleijnse ML,Sluiter W,Vydt TC,Soliman OI,van Dalen BM,Vletter WB,ten Cate FJ,Smeets HJ,de Coo RF

    更新日期:2009-02-21 00:00:00

  • Strengths and weaknesses of chest compression training: a preliminary retrospective study.

    abstract:BACKGROUND:High quality chest compression is one of the key factors in successful resuscitation. A high standard of training is therefore decisive. We aimed to investigate the strengths and weaknesses of teaching chest compression in a study designed to highlight where targeted improvements in the quality of our chest ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2011.13221

    authors: Osterwalder JJ,Braun D

    更新日期:2011-07-01 00:00:00

  • Physical activity behaviour in patients with metabolic syndrome.

    abstract:STUDY/PRINCIPLES:Physical activity improves the clinical course of the metabolic syndrome and its risk factors. The aim of this study was to investigate the physical activity behaviour in patients with metabolic syndrome in regard to the recommendation of the Federal Offices of Public Health (BAG) and Sports (BASPO): "...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2012.13691

    authors: Murer M,Schmied C,Battegay E,Keller DI

    更新日期:2012-10-25 00:00:00

  • "Real world" experience in Cardiac Resynchronization Therapy at a Swiss Tertiary Care Center.

    abstract:BACKGROUND:Based on a reduction in morbidity and mortality, cardiac resynchronisation therapy (CRT) has evolved as a standard therapy for patients with advanced heart failure. OBJECTIVE:To provide insight into patient demographics, safety, echocardiographic remodelling and long-term follow-up of patients treated with ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2017.14425

    authors: Winnik S,Elsener C,Seifert B,Starck C,Straub A,Saguner AM,Breitenstein A,Krasniqi N,Wilhelm MJ,Haegeli L,Duru F,Benussi S,Maisano F,Lüscher TF,Holzmeister J,Huerlimann D,Ruschitzka F,Steffel J

    更新日期:2017-04-18 00:00:00

  • Bosentan for patients with steroid-resistant pulmonary sarcoidosis: a randomised controlled trial.

    abstract:BACKGROUND:Sarcoidosis is a disorder of unknown aetiology. Most patients have steroid-responsive disease, but side effects and steroid resistance may necessitate alternative treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis. OBJECTIVES:We studied the efficacy...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,随机对照试验

    doi:10.4414/smw.2018.14677

    authors: Hostettler K,Baty F,Kleiner R,Junker L,Tamm M,Brutsche M

    更新日期:2018-10-28 00:00:00

  • Social, cultural and experiential patterning of attitudes and behaviour towards assisted suicide in Switzerland: evidence from a national population-based study.

    abstract::Switzerland has the longest history of the legal practice of non-physician assisted suicide of any country. Assisted suicide is not very tightly regulated in Switzerland, and almost all assisted suicides are supported by a right-to-die organisation. Our study investigates older adults’ attitudes and behaviour to...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2020.20275

    authors: Vilpert S,Bolliger E,Borrat-Besson C,Borasio GD,Maurer J

    更新日期:2020-07-01 00:00:00

  • The role of rituximab in the treatment of ANCA-associated vasculitides (AAV).

    abstract::The antineutrophil cytoplasmic antibody (ANCA) associated vasculitides (AAV) are a group of primary vasculitides that affect predominantly small- to medium-sized blood vessels. AAV include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). D...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2015.14103

    authors: Daikeler T,Kistler AD,Martin PY,Vogt B,Huynh-Do U

    更新日期:2015-02-06 00:00:00

  • The impact of clinical trial units on the value of clinical research in Switzerland.

    abstract::A prominent 2014 series by The Lancet on "Increasing value, reducing waste in biomedical research" provided recommendations on how to optimise precious resources, including in clinical research. Despite being ideally placed to lead the movement in patient-oriented clinical research, academia struggles to take correspo...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2018.14615

    authors: von Niederhäusern B,Magnin A,Pauli-Magnus C

    更新日期:2018-04-26 00:00:00

  • Is the Eichenholtz classification still valid for the diabetic Charcot foot?

    abstract::In his 1966 monograph "Charcot joints", Sidney N. Eichenholtz (1909-2000) described "three well defined stages … in the course and development of a Charcot joint", based on plain X-rays of 68 patients. Since then, medical imaging has advanced very much: computed tomography and magnetic resonance imaging (MRI) scans ex...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:10.4414/smw.2014.13948

    authors: Chantelau EA,Grützner G

    更新日期:2014-04-24 00:00:00

  • Work-life conflicts and health among Swiss physicians--in comparison with other university graduates and with the general Swiss working population.

    abstract:QUESTION UNDER STUDY:The present study aimed to compare the prevalence of work-life conflicts and the health status of physicians, with a representative sample of university graduates as well as with a representative sample of the general Swiss working population. Furthermore, it aimed to analyse whether work-life conf...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2010.13063

    authors: Knecht M,Bauer GF,Klaghofer R,Buddeberg-Fischer B,Stamm M,Hämmig O

    更新日期:2010-07-11 00:00:00

  • Molecular determinants for amyloid fibril formation: lessons from lung surfactant protein C.

    abstract::Amyloid fibrils are polymers composed of proteins in beta-sheet conformation, which are found in at least 20 diseases for which no cure is available. These diseases include Alzheimer's disease and spongiform encephalopathies, in which the amyloid beta-peptide and the prion protein (PrP), respectively, form amyloid. Al...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章,评审

    doi:2003/19/smw-09987

    authors: Johansson J

    更新日期:2003-05-17 00:00:00

  • Additional malignancies in patients with neuroendocrine tumours: analysis of the SwissNET registry.

    abstract:PRINCIPLES:Neuroendocrine neoplasms (NENs) are believed to be associated with an increased risk for additional malignancies (AMs). We aimed to (1) assess the occurrence of AM in NEN patients (2) investigate the characteristics and temporal relationship of NEN patients with and without AM. METHODS:The SwissNET registry...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:10.4414/smw.2016.14362

    authors: Kollár A,Blank A,Perren A,Bütikofer L,Stettler C,Christ E

    更新日期:2016-11-12 00:00:00

  • Bronchodilator response in residual volume in irreversible airway obstruction.

    abstract:BACKGROUND:Although airway obstruction, as defined by improvement of forced expiratory volume in one second (FEV1) and/or forced vital capacity (FVC), is irreversible in patients with COPD, they clearly seem to benefit from treatment with inhaled bronchodilators. AIMS:To assess the response pattern of residual volume ...

    journal_title:Swiss medical weekly

    pub_type: 杂志文章

    doi:2008/17/smw-11992

    authors: Balestra AM,Bingisser RB,Chhajed PN,Tamm M,Leuppi JD

    更新日期:2008-05-03 00:00:00