Steroid regulation of menstrual bleeding and endometrial repair.

abstract：:The vascular endothelium has been identified as an important component in diabetes-associated complications, which include many cardiovascular disorders such as atherosclerosis, hypertension and peripheral neuropathy. Additionally, insulin's actions on the endothelium are now seen as a major factor in the metabolic ef...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kolka CM,Bergman RN

更新日期：2013-03-01 00:00:00

abstract：:Myo-inositol (Myo-Ins) plays an important role in thyroid function and autoimmunity. Myo-Ins is the precursor for the synthesis of phosphoinositides, which takes part in the phosphatidylinositol (PtdIns) signal transduction pathway, and plays a decisive role in several cellular processes. In the thyroid cells, PtdIns ...

journal_title：Reviews in endocrine & metabolic disorders

authors： Fallahi P,Ferrari SM,Elia G,Ragusa F,Paparo SR,Caruso C,Guglielmi G,Antonelli A

更新日期：2018-12-01 00:00:00

abstract：:The term "HCV syndrome" encompasses several organ- and systemic pathophysiological states, which often recognize autoimmunity or neoplastic evolution in their pathophysiology, as well as chronic HCV infection as trigger. The clinical features of HCV patients are heterogenous, and may include endocrine or metabolic dis...

journal_title：Reviews in endocrine & metabolic disorders

authors： Colaci M,Malatino L,Antonelli A,Fallahi P,Giuggioli D,Ferri C

更新日期：2018-12-01 00:00:00

abstract：:The prevalence of convenience-driven delivery via Caesarian-section (C-section) has been steadily increasing in Western as well as in developing societies. Today, significantly more deliveries occur via surgical means than medical necessity mandates. Despite tremendous advances in surgical techniques and pre- and post...

journal_title：Reviews in endocrine & metabolic disorders

authors： Seli E,Horvath TL

更新日期：2013-12-01 00:00:00

abstract：:Impulsivity and compulsivity are multidimensional constructs that are increasingly considered determinants of obesity. Studies using functional magnetic resonance imaging (fMRI) have provided insight on how differences in brain response during tasks exploring facets of impulsivity and compulsivity relate to the ingest...

journal_title：Reviews in endocrine & metabolic disorders

authors： Steward T,Miranda-Olivos R,Soriano-Mas C,Fernández-Aranda F

更新日期：2019-09-01 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular disease (CVD). One theory to explain this relationship proposes that OSA can induce systemic inflammation, thereby inducing CVD. This theory is based on the premise that obesity is a pro-inflammatory state, and that physiological derange...

journal_title：Reviews in endocrine & metabolic disorders

authors： Unnikrishnan D,Jun J,Polotsky V

更新日期：2015-03-01 00:00:00

abstract：:Weight gain at the outset of prolactinomas in many women is well documented. Yet, this symptom is absent from the clinical descriptions of the disease in textbooks and reviews. This omission is almost certainly due to the absence of a physiological explanation for the phenomenon, as prolactin is not a recognized fat p...

journal_title：Reviews in endocrine & metabolic disorders

authors： Sobrinho LG,Horseman ND

更新日期：2019-06-01 00:00:00

abstract：:Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of tumors, mainly localized in the gastrointestinal system. What characterizes NENs is the expression of hormone receptors on the tumor cell surface, making them accessible for diagnostic and therapeutic approaches (theranostics) using radiolabelled peptid...

journal_title：Reviews in endocrine & metabolic disorders

authors： Refardt J,Hofland J,Kwadwo A,Nicolas GP,Rottenburger C,Fani M,Wild D,Christ E

更新日期：2020-06-03 00:00:00

abstract：:The ATP-sensitive potassium (K(ATP)) channel is composed of two subunits SUR1 and Kir6.2. The channel is key for glucose stimulated insulin release from the pancreatic beta cell. Activating mutations have been identified in the genes encoding these subunits, ABCC8 and KCNJ11, and account for approximately 40% of perma...

journal_title：Reviews in endocrine & metabolic disorders

authors： Edghill EL,Flanagan SE,Ellard S

更新日期：2010-09-01 00:00:00

abstract：:With the dramatically increasing prevalence of obesity and type 2 diabetes mellitus (T2DM) worldwide, there is an urgent need for new strategies to combat the growing epidemic of these metabolic diseases. Diet is an essential factor affecting the development of and risk for obesity and T2DM and it can either help or h...

journal_title：Reviews in endocrine & metabolic disorders

authors： Guo H,Ling W

更新日期：2015-03-01 00:00:00

abstract：:Pituitary tumors are among the most common neoplasms in man; they account for approximately 15% of all primary intracranial lesions (Jagannathan et al., Neurosurg Focus, 19:E4, 2005). Although almost never malignant and rarely clinically expressed, pituitary tumors may cause significant morbidity in affected patients....

journal_title：Reviews in endocrine & metabolic disorders

authors： Horvath A,Stratakis CA

更新日期：2008-03-01 00:00:00

abstract：:The last decade has been characterized by an intense research on the composition of the gut microbiome and the links with human health. While previous work was focused on the effects of prebiotics and probiotics, nowadays several laboratories are describing the gut microbiome and its metabolic functions. Gut microbiom...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kappel BA,Federici M

更新日期：2019-12-01 00:00:00

abstract：:Glucokinase is a key enzyme involved in regulating insulin secretion from the pancreatic ß-cell. The unique role of glucokinase in human glucose physiology is illustrated by the fact that genetic mutations in glucokinase can either cause hyperglycaemia or hypoglycaemia. Heterozygous inactivating mutations in glucokina...

journal_title：Reviews in endocrine & metabolic disorders

authors： Hussain K

更新日期：2010-09-01 00:00:00

abstract：:It is widely acknowledged that compliance and persistence with oral osteoporosis medications, particularly with bisphosphonates, is poor. Several excellent reviews have been written on compliance and persistence with osteoporosis medications and have discussed improvements seen with extended dosing intervals. This rev...

journal_title：Reviews in endocrine & metabolic disorders

authors： Silverman S,Gold DT

更新日期：2010-12-01 00:00:00

abstract：:Intrauterine growth retardation (IUGR) has been linked to later development of type 2 diabetes in adulthood. Human studies indicate that individuals who were growth retarded at birth have impaired insulin secretion and insulin resistance. Multiple animal models of IUGR demonstrate impaired beta-cell function and devel...

journal_title：Reviews in endocrine & metabolic disorders

authors： Simmons RA

更新日期：2007-06-01 00:00:00

abstract：:Lifestyle changes such as dietary habits, sedentary life and consumption of energy-dense foods that have occurred over the years has led to an epidemic of abdominal obesity, which in turn resulted in dramatic increase in the prevalence of metabolic syndrome (MetS). Different expert panels have provided various definit...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kumar PA,Chitra PS,Reddy GB

更新日期：2013-09-01 00:00:00

abstract：:T3 suppression of TSH subunit gene transcription is an important step in maintaining thyroid hormone homeostasis, and recent investigations have increased our understanding of this process. Thyrotrope-specific proteins play a critical role in TSH subunit gene expression, and influence T3-mediated regulatory mechanisms...

journal_title：Reviews in endocrine & metabolic disorders

authors： Shupnik MA

更新日期：2000-01-01 00:00:00

abstract：:The skeletal muscle is one of the major target organs of insulin and plays an essential role in insulin-induced glucose uptake. Some evidence indicates that insulin delivery to skeletal muscle interstitium through the endothelial cells is the rate-limiting step in insulin-stimulated glucose uptake. Researchers have al...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kubota T,Kubota N,Kadowaki T

更新日期：2013-06-01 00:00:00

abstract：:In the last 10 years, several studies have shown that the pancreas of patients with type 1 diabetes (T1D), and even of subjects at risk for T1D, was smaller than the pancreas from healthy subjects. This arose the question of the relationships between the endocrine and exocrine parts of the pancreas in T1D pathogenesis...

journal_title：Reviews in endocrine & metabolic disorders

authors： Alexandre-Heymann L,Mallone R,Boitard C,Scharfmann R,Larger E

更新日期：2019-06-01 00:00:00

abstract：:Abdominal obesity and elevated blood pressure commonly occur in the same patient and are key components of the metabolic syndrome. However, the association between obesity and increased blood pressure is variable. We review mechanisms linking cardiovascular and metabolic disease in such patients including altered syst...

journal_title：Reviews in endocrine & metabolic disorders

authors： Jordan J,Birkenfeld AL

更新日期：2016-03-01 00:00:00

abstract：:Deleterious mutations in two breast and ovarian cancer susceptibility genes, BRCA1 and BRCA2 have been identified in breast and ovarian cancer families. Women with a BRCA1 or BRCA2 mutation are candidates for additional risk reduction measures such as intensive screening, prophylactic surgery or chemoprevention. Addit...

journal_title：Reviews in endocrine & metabolic disorders

authors： Bradbury AR,Olopade OI

更新日期：2007-09-01 00:00:00

abstract：:Diabetes mellitus is a chronic, progressive, incompletely understood metabolic disorder whose prevalence has been increasing steadily worldwide. Even though little attention has been paid to lung disorders in the context of diabetes, its prevalence has recently been challenged by newer studies of disease development. ...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kolahian S,Leiss V,Nürnberg B

更新日期：2019-09-01 00:00:00

abstract：:Diabetes is a group of metabolic disorders characterized by persistent hyperglycemia and has become a major public health concern. Autoimmune type 1 diabetes (T1D) and insulin resistant type 2 diabetes (T2D) are the two main types. A combination of genetic and environmental factors contributes to the development of th...

journal_title：Reviews in endocrine & metabolic disorders

authors： Tai N,Wong FS,Wen L

更新日期：2015-03-01 00:00:00

abstract：:Celiac disease is a chronic enteropathy caused by permanent intolerance to gluten and similar proteins found in wheat, barley and rye. The intestinal mucosa of susceptible individuals is crossed by undigested gluten, which leads to a marked inflammatory response. The clinical features may vary from overt intestinal sy...

journal_title：Reviews in endocrine & metabolic disorders

authors： Mora S

更新日期：2008-06-01 00:00:00

abstract：:An emerging branch of research is examining the linkage between Vitamin D and nonskeletal disorders, including endocrine diseases. In this regard, a still little studied aspect concerns the involvement of vitamin D in adrenal gland disorders. Adrenal gland disorders, which might be theoretically affected by vitamin D ...

journal_title：Reviews in endocrine & metabolic disorders

authors： Tirabassi G,Salvio G,Altieri B,Ronchi CL,Della Casa S,Pontecorvi A,Balercia G

更新日期：2017-09-01 00:00:00

abstract：:Adiponectin is among the most studied adipokines, the collection of molecules secreted from adipose tissue. It is also one of the most architecturally complex adipokines with its various oligomeric states that include trimers, hexamers, nonamers (9mers), dodecamers (12mers), and octadecamers (18mers). The importance o...

journal_title：Reviews in endocrine & metabolic disorders

authors： Tsao TS

更新日期：2014-06-01 00:00:00

abstract：:Methionine and folate are the key components of one carbon metabolism, providing the methyl groups for numerous methyl transferase reactions via the ubiquitous methyl donor, s-adenosyl methionine. Methionine metabolism is responsive to nutrient intake, is regulated by several hormones and requires a number of vitamins...

journal_title：Reviews in endocrine & metabolic disorders

authors： Kalhan SC,Marczewski SE

更新日期：2012-06-01 00:00:00

abstract：:Despite their critical role in susceptibility to metabolic diseases such as obesity and type 2 diabetes, mechanisms regulating energy balance are extremely complex and far from being fully understood. Both central and peripheral feedback circuits are involved and, despite it was traditionally thought that the energy b...

journal_title：Reviews in endocrine & metabolic disorders

authors： Vettor R,Di Vincenzo A,Maffei P,Rossato M

更新日期：2020-09-01 00:00:00

abstract：:Vitamin D is a key hormone involved in the regulation of calcium/phosphorous balance and recently it has been implicated in the pathogenesis of sub-inflammation, insulin resistance and obesity. The two main forms of vitamin D are cholecalciferol (Vitamin D3) and ergocalciferol (Vitamin D2): the active form (1,25-dihyd...

journal_title：Reviews in endocrine & metabolic disorders

authors： Garbossa SG,Folli F

更新日期：2017-06-01 00:00:00

abstract：:Incretin hormones are intestinally derived peptides that are known to augment glucose-stimulated insulin secretion and suppress glucagon levels. Incretin mimetics are attractive adjunctive therapy for type 2 diabetes due to its efficacy on reducing hyperglycemia with a minimal risk of hypoglycemia. In contrast to most...

journal_title：Reviews in endocrine & metabolic disorders

authors： Tong J,Sandoval DA

更新日期：2011-09-01 00:00:00