CXCR4 positive and angiogenic monocytes in myocardial infarction.

abstract：:Patterns of VIIIR:AG in the plasma and its fractions, cryoprecipitate and cryosupernatant, from various types of von Willebrand's disease (vWd) were observed by SDS 1.5% polyacrylamide gel electrophoresis - cross immunoelectrophoresis (SDS PAGE - CIE). VIIIR:AG in normal cryoprecipitate showed several precipitin peaks...

journal_title：Thrombosis and haemostasis

authors： Mikami S,Takahashi Y,Nishino M,Okubo Y,Fukui H

更新日期：1981-06-30 00:00:00

abstract：:Despite years of research and efforts to translate stroke research to clinical therapy, ischaemic stroke remains a major cause of death, disability, and diminished quality of life. Primary and secondary preventive measures combined with improved quality of care have made significant progress. However, no novel drug fo...

journal_title：Thrombosis and haemostasis

authors： Mosnier LO,Zlokovic BV,Griffin JH

更新日期：2014-11-01 00:00:00

abstract：:An assay for the quantification of pentosan polysulphate (PPS) in plasma is described. As PPS has been shown to potentiate thrombin inhibition by the second heparin cofactor (HC II), the principle of this assay was to measure the formation of covalent complexes between HC II and the thrombin generated in plasma after ...

journal_title：Thrombosis and haemostasis

authors： Dol F,Sié P,Dupouy D,Boneu B

更新日期：1986-12-15 00:00:00

abstract：:Plasma samples from 35 patients with colorectal cancer, 16 patients with pancreatic cancer and 46 patients with various cancers in the terminal stage were analysed for soluble plasma thrombomodulin with an ELISA method. At time of diagnosis and before primary treatment, the patients with colorectal cancer had normal p...

journal_title：Thrombosis and haemostasis

authors： Lindahl AK,Boffa MC,Abildgaard U

更新日期：1993-02-01 00:00:00

abstract：:Atrial fibrillation (AF) is a common complication of coronary artery bypass grafting (CABG). We sought to determine the diagnostic validity of plasma biomarkers of i) inflammation (marked by interleukin-6 [IL-6] and high-sensitivity C-reactive protein [hs-CRP]), ii) extracellular matrix remodelling (matrix metalloprot...

journal_title：Thrombosis and haemostasis

authors： Kaireviciute D,Blann AD,Balakrishnan B,Lane DA,Patel JV,Uzdavinys G,Norkunas G,Kalinauskas G,Sirvydis V,Aidietis A,Lip GY

更新日期：2010-07-01 00:00:00

abstract：:We measured and compared the levels of plasma soluble (s) P-selectin, sCD40L, platelet-derived microparticles (PDMP), monocyte-derived microparticles (MDMP), and anti-oxidized LDL antibody, to obtain a better understanding of their potential contribution to vascular complications in acute coronary syndrome (ACS). The ...

journal_title：Thrombosis and haemostasis

authors： Matsumoto N,Nomura S,Kamihata H,Kimura Y,Iwasaka T

更新日期：2004-01-01 00:00:00

abstract：:Recently we prepared sulfated, low-molecular-weight lignins (LMWLs) to mimic the biological activities of heparin and heparan sulfate. Chemo-enzymatically prepared sulfated LMWLs represent a library of diverse non-sugar, aromatic molecules with structures radically different from the heparins, and have been found to p...

journal_title：Thrombosis and haemostasis

authors： Henry BL,Abdel Aziz M,Zhou Q,Desai UR

更新日期：2010-03-01 00:00:00

abstract：:Vasopressin infusions in normal volunteers that produce concentrations in plasma comparable to those seen during stress, cause an increase in plasma factor VIII and shortening of the euglobulin clot lysis time (ECLT). We have investigated the relationship between endogenous vasopressin (aVP) release and haemostatic fu...

journal_title：Thrombosis and haemostasis

authors： Grant PJ,Tate GM,Davies JA,Williams NS,Prentice CR

更新日期：1986-02-28 00:00:00

abstract：:The calcium electrode is a convenient, inexpensive, and non-traumatic method for measuring changes in the extracellular calcium which accompanies a platelet release reaction. With this instrument, the temporal pattern of release by platelets in a buffered-saline medium following thrombin stimulation was observed as fo...

journal_title：Thrombosis and haemostasis

authors： Robblee LS,Kornstein LB,Shepro D

更新日期：1977-06-30 00:00:00

abstract：:Deep-vein thrombosis (DVT) is a common condition that often leads to pulmonary thromboembolism (VTE) and death. The role of prostaglandin-endoperoxide synthase (PTGS)2 in arterial thrombosis has been well established, whereas its impact in venous thrombosis remains unclear. Here, we showed that PTGS2 deletion predispo...

journal_title：Thrombosis and haemostasis

authors： Amadio P,Tarantino E,Sandrini L,Tremoli E,Barbieri SS

更新日期：2017-07-26 00:00:00

abstract：:Filtration through asbestos filter (Seitz) of human plasma modified the prothrombin molecule as previously shown. Factor II could no longer be activated by physiological activators (Ca++ + phospholipid + V and Xa) but reacted readily with staphylocoagulase. The separation and purification of the modified prothrombin a...

journal_title：Thrombosis and haemostasis

authors： Izuchi Y,Boffa MC,Soulier JP

更新日期：1979-02-15 00:00:00

abstract：:Cell accumulation is a prerequisite for adipose tissue inflammation. The leukocyte integrin Mac-1 (CD11b/CD18, αMβ2) is a classic adhesion receptor critically regulating inflammatory cell recruitment. Here, we tested the hypothesis that a genetic deficiency and a therapeutic modulation of Mac-1 regulate adipose tissue...

journal_title：Thrombosis and haemostasis

authors： Wolf D,Bukosza N,Engel D,Poggi M,Jehle F,Anto Michel N,Chen YC,Colberg C,Hoppe N,Dufner B,Boon L,Blankenbach H,Hilgendorf I,von Zur Muhlen C,Reinöhl J,Sommer B,Marchini T,Febbraio MA,Weber C,Bode C,Peter K,Lutge

更新日期：2017-01-26 00:00:00

abstract：:Tissue factor (TF) markedly enhances the ability of factor VIIa (FVIIa) to cleave both macromolecular and small peptidyl substrates. Using soluble mutant TF (sTF) to investigate TF-enhanced FVIIa amidolytic activity in solution, we screened thirty-four commercially available peptidyl-p-nitroanilide substrates and foun...

journal_title：Thrombosis and haemostasis

authors： Neuenschwander PF,Branam DE,Morrissey JH

更新日期：1993-12-20 00:00:00

abstract：:East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y12 receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral anticoagulants are commonly used in current daily practice, the unique risk-benefit ...

journal_title：Thrombosis and haemostasis

authors： Kim HK,Tantry US,Smith SC Jr,Jeong MH,Park SJ,Kim MH,Lim DS,Shin ES,Park DW,Huo Y,Chen SL,Bo Z,Goto S,Kimura T,Yasuda S,Chen WJ,Chan M,Aradi D,Geisler T,Gorog DA,Sibbing D,Lip GYH,Angiolillo DJ,Gurbel PA,J

更新日期：2020-11-10 00:00:00

abstract：:Erythropoietin has shown to be effective in the correction of the hemostatic defect present in uremic patients. We have investigated the possible effect of recombinant human erythropoietin (rHuEPO) on the signaling processes occurring in platelets. Platelet suspensions were obtained from hemodialyzed patients before a...

journal_title：Thrombosis and haemostasis

authors： Diaz-Ricart M,Etebanell E,Cases A,López-Pedret J,Castillo R,Ordinas A,Escolar G

更新日期：1999-10-01 00:00:00

abstract：:The core protein components of the plasminogen activator (PA) system are two plasminogen activators, two plasminogen activator inhibitors and a urokinase type plasminogen activator-specific cell surface receptor. Various types of biological regulation are exerted through the interplay of these components mutually and ...

journal_title：Thrombosis and haemostasis

authors： Nagamine Y,Medcalf RL,Muñoz-Cánoves P

更新日期：2005-04-01 00:00:00

abstract：:Peripheral vascular disease (PVD) is an indicator of diffuse atherosclerosis and is associated with a greatly increased incidence of coronary heart and cerebrovascular disease. Although several studies have assessed whether in vivo platelet activation takes place in patients with PVD, no data are available comparing d...

journal_title：Thrombosis and haemostasis

authors： Gresele P,Catalano M,Giammarresi C,Volpato R,Termini R,Ciabattoni G,Nenci GG,Davì G

更新日期：1997-12-01 00:00:00

abstract：:The novel fast inhibitor to tissue plasminogen activator in plasma has been determined in 20 healthy non-pregnant women, 48 apparently healthy pregnant women and 136 women with risk pregnancies (preeclampsia, suspected fetal growth retardation, thrombosis or previous history of thrombosis, diabetes and others). In hea...

journal_title：Thrombosis and haemostasis

authors： Wiman B,Csemiczky G,Marsk L,Robbe H

更新日期：1984-10-31 00:00:00

abstract：:Expression of isolated beta integrin cytoplasmic domains in cultured endothelial cells was reported to induce cell detachment and death. To test whether cell death was the cause or the consequence of cell detachment, we expressed isolated integrin beta1 cytoplasmic and transmembrane domains (CH1) in cultured human umb...

journal_title：Thrombosis and haemostasis

authors： Hasmim M,Vassalli G,Alghisi GC,Bamat J,Ponsonnet L,Bieler G,Bonnard C,Paroz C,Oguey D,Rüegg C

更新日期：2005-11-01 00:00:00

abstract：:A synthetic hirudin55-65 C-terminal fragment analog was evaluated for anticoagulant activity and in models of experimental thrombosis in mice and rats. Intravenous injection caused dose-related inhibition of thrombin and anticoagulation in rat blood samples, protection from thromboembolism in mice and inhibition of st...

journal_title：Thrombosis and haemostasis

authors： Broersma RJ,Kutcher LW,Heminger EF,Krstenansky JL,Marshall FN

更新日期：1991-04-08 00:00:00

abstract：:Antiphospholipid antibodies are a risk factor for venous and arterial thrombosis and may contribute to the development of atherosclerosis.The aim of this study was to investigate whether antibodies to human beta2-glycoprotein 1 (beta2GP1), as a model of antiphospholipid antibodies, modify the phenotype of atherosclero...

journal_title：Thrombosis and haemostasis

authors： Dunoyer-Geindre S,Kwak BR,Pelli G,Roth I,Satta N,Fish RJ,Reber G,Mach F,Kruithof EK,de Moerloose P

更新日期：2007-01-01 00:00:00

abstract：:Amniotic fluid inhibited the fibrinolytic, amidolytic and esterolytic activity of urokinase. Kinetic studies with AGLMe demonstrated non-competitive inhibition. A major part of the inhibitory activity could be separated from alpha 1-antitrypsin by ion-exchange chromatography on DEAE-Sephadex A-50. Plasminogen activato...

journal_title：Thrombosis and haemostasis

authors： Walker JE,Campbell DM,Ogston D

更新日期：1980-08-29 00:00:00

abstract：:The origin and evolution of venom toxins is a mystery that has evoked much interest. We have recently shown that pseutarin C, a prothrombin activator from Pseudonaja textilis venom, is structurally and functionally similar to mammalian coagulation factor Xa-factor Va complex. Its catalytic subunit is homologous to fac...

journal_title：Thrombosis and haemostasis

authors： Minh Le TN,Reza MA,Swarup S,Kini RM

更新日期：2005-03-01 00:00:00

abstract：:We report on three unrelated individuals with the same uncommon type of dysfibrinogenemia, originating from Bergamo, Essen and Perugia. None of them showed bleeding symptoms while the Bergamo patient and members of her family presented with a thrombotic tendency. The presence of a defective fibrinogen was suggested by...

journal_title：Thrombosis and haemostasis

authors： Reber P,Furlan M,Henschen A,Kaudewitz H,Barbui T,Hilgard P,Nenci GG,Berrettini M,Beck EA

更新日期：1986-12-15 00:00:00

abstract：:Sixty nine patients were treated with local intra-arterial urokinase (37,500 U/CTA. hr-1) for recent severe ischemia of lower limbs: 27 (40%) ultimately required amputation. The difference of amputation rate between the groups with and without thrombolysis was not significant (33% v. 42%). A biological study in 6 pati...

journal_title：Thrombosis and haemostasis

authors： Fiessinger JN,Aiach M,Capron L,Devanlay M,Vayssairat M,Juillet Y

更新日期：1981-06-30 00:00:00

abstract：:We have identified two novel minor deletions (case 1; -TA or -AT at nucleotide 9831-3 in exon 5 and case 2; -A at nucleotide 7640-1 in exon 4), one novel nonsense mutation (case 3; TAT to TAA at nucleotide 7491 in exon 4), and one recurrent nonsense mutation (case 4; CGA to TGA at nucleotide 5381 in exon 3A) in Japane...

journal_title：Thrombosis and haemostasis

authors： Nakahara Y,Tsuji H,Nakagawa K,Masuda H,Kitamura H,Nishimura H,Kasahara T,Sugano T,Sawada S,Nakagawa M

更新日期：1997-04-01 00:00:00

abstract：:A pulmonary embolism model in hamsters was used for the quantitative evaluation of the thrombolytic and pharmacokinetic properties of variants of tissue-type plasminogen activator (t-PA). A 25 microliters 125I-fibrin labeled human plasma clot was made in vitro and injected into the jugular vein of heparinized hamsters...

journal_title：Thrombosis and haemostasis

authors： Collen D,Lijnen HR,Vanlinthout I,Kieckens L,Nelles L,Stassen JM

更新日期：1991-02-12 00:00:00

abstract：:Clot retraction is an essential step during primary haemostasis, thereby promoting thrombus stability and wound healing. Integrin αIIbβ3 plays a critical role in clot retraction, by inducing acto-myosin interactions that allow platelet cytoskeleton reorganisation. However, the signalling pathways that lead to clot ret...

journal_title：Thrombosis and haemostasis

authors： Egot M,Kauskot A,Lasne D,Gaussem P,Bachelot-Loza C

更新日期：2013-12-01 00:00:00

abstract：:The release of microvesicles ('platelet microparticles', PMPs) by activated platelets has been shown to be an integral part of the thrombotic process. PMPs are believed to mediate many biological processes as they possess various platelet membrane proteins and bioactive lipids. Of note, there is a growing body of evid...

journal_title：Thrombosis and haemostasis

authors： Tan KT,Lip GY

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Preliminary evidence suggests that use of antipsychotic drugs is associated with an increased risk of venous thromboembolism. OBJECTIVE:To evaluate the relationship between antipsychotic or antidepressant drug use and venous thromboembolism among adults aged 65 years and older. DESIGN:Retrospective cohort ...

journal_title：Thrombosis and haemostasis

authors： Ray JG,Mamdani MM,Yeo EL

更新日期：2002-08-01 00:00:00