Abstract:
:An extensive investigation was carried out to describe the kinetics of cell growth, substrate consumption, and product formation in the batch fermentation using starch as substrate. Evaluation of intrinsic kinetic parameters was carried out using a best-fit unstructured model. A nonlinear regression technique was applied for computational purpose. The Andrew's model showed a comparatively better R2 value among all tested models. The values of specific growth rate (micronmax), saturation constant (KS), inhibition constant (KI), and YX/S were found to be 0.109 h-1, 11.1 g/l, 0.012 g/l, and 1.003, respectively. The Leudeking- Piret model was used to study the product formation kinetics and the process was found to be growth-associated. The growth-associated constant (alpha) for protease production was sensitive to substrate concentration. Its value was fairly constant up to a substrate concentration of 30.8 g/l, and then decreased.
journal_name
J Microbiol Biotechnoljournal_title
Journal of microbiology and biotechnologyauthors
Bhunia B,Basak B,Bhattacharya P,Dey Adoi
10.4014/jmb.1206.06015subject
Has Abstractpub_date
2012-12-01 00:00:00pages
1758-66issue
12eissn
1017-7825issn
1738-8872pii
JMB022-12-21journal_volume
22pub_type
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