Cancer mortality and some socio economic correlates in Rosario, Argentina.

Abstract:

:The age-standardized mortality rates by sex for cancer of all sites and some specific sites were calculated in the 22 areas of Rosario (Argentina). The rates by area were correlated with education, occupation, housing quality and population density, applying Kendall's tau. Cervical cancer rates showed the strongest correlations, which were positive with illiteracy, unqualified occupations and poor housing. These variables presented positive correlations with stomach cancer also, which were more significant in males than in females. Colon and breast cancer rates had positive correlations with the highest levels of education, occupational status, housing conditions and population density.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Poletto L,Morini JC

doi

10.1016/0304-3835(90)90159-u

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

201-5

issue

3

eissn

0304-3835

issn

1872-7980

pii

0304-3835(90)90159-U

journal_volume

49

pub_type

杂志文章
  • CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma.

    abstract::The chemokine CXCL12 (SDF-1) and its receptor, CXCR4, have been implicated in organ-specific metastases of several malignancies. Head and neck squamous cell carcinoma (HNSCC) predominantly metastasizes to lymph nodes, and recent evidence has shown that CXCL12 stimulates HNSCC migration. We explored the potential role ...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2004.04.035

    authors: Samara GJ,Lawrence DM,Chiarelli CJ,Valentino MD,Lyubsky S,Zucker S,Vaday GG

    更新日期:2004-10-28 00:00:00

  • Modification of photocarcinogenesis by two immunosuppressive agents.

    abstract::The carcinogenic effect of ultraviolet radiation (UVR) on the skin of hairless (hr) mice was modified by two immunosuppressive agents, rabbit anti-mouse lymphocytic serum (ALS), and 6-mercaptopurine (6MP). Daily exposure of mice to UVR resulted in multiple tumor production. Carcinogenesis was measured in terms of affe...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3835(75)97305-x

    authors: Nathanson RB,Forbes PD,Urbach F

    更新日期:1976-05-01 00:00:00

  • Rotenone, an anticarcinogen, inhibits cellular proliferation but not peroxisome proliferation in mouse liver.

    abstract::In previous National Toxicology Program (NTP) studies, rotenone reduced the background incidence of hepatocellular carcinoma in male B6C3F1 mice. In the present studies, rotenone reduced the basal hepatic labeling index of male B6C3F1 mice in a dose-dependent fashion and inhibited hepatocellular proliferation, but not...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(95)03869-x

    authors: Cunningham ML,Soliman MS,Badr MZ,Matthews HB

    更新日期:1995-08-16 00:00:00

  • Telomerase as tumor marker.

    abstract::Telomerase, a critical enzyme responsible for continuous cell growth, is repressed in most somatic cells except proliferating progenitor cells and activated lymphocytes, and activated in approximately 85% of human cancer tissues. Telomerase activity is a useful cancer-cell detecting marker in some types of cancers in ...

    journal_title:Cancer letters

    pub_type: 杂志文章,评审

    doi:10.1016/s0304-3835(02)00709-7

    authors: Hiyama E,Hiyama K

    更新日期:2003-05-15 00:00:00

  • Metformin displays anti-myeloma activity and synergistic effect with dexamethasone in in vitro and in vivo xenograft models.

    abstract::Epidemiologic studies and meta-analyses have suggested that patients with type 2 diabetes mellitus (T2DM) have a higher incidence of malignancies, including myeloma. Metformin is a widely prescribed antidiabetic drug. Recently, researchers have shown that metformin has direct anticancer activity against many tumor cel...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2014.09.050

    authors: Zi FM,He JS,Li Y,Wu C,Yang L,Yang Y,Wang LJ,He DH,Zhao Y,Wu WJ,Zheng GF,Han XY,Huang H,Yi Q,Cai Z

    更新日期:2015-01-28 00:00:00

  • Calpain 6 supports tumorigenesis by inhibiting apoptosis and facilitating angiogenesis.

    abstract::Since calpain 6 is overexpressed in uterine cervical cancer tissue compared to normal tissue, we sought to define the role of calpain 6 during tumorigenesis. We overexpressed calpain 6 or inhibited calpain 6 in human cervical cancer cells (HeLa cells) and human umbilical vein endothelial cells (HUVECs), and measured c...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2008.06.020

    authors: Rho SB,Byun HJ,Park SY,Chun T

    更新日期:2008-11-28 00:00:00

  • Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis.

    abstract::To determine if the carcinogenic potential of peroxisome proliferators is dependent upon their ability to induce cell proliferation, we have investigated the extent of cell proliferation in the livers of rats fed ciprofibrate, a peroxisome proliferator. Male rats were maintained on a diet containing ciprofibrate (0.02...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(89)90172-9

    authors: Yeldandi AV,Milano M,Subbarao V,Reddy JK,Rao MS

    更新日期:1989-09-15 00:00:00

  • TACC3 promotes epithelial-mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways.

    abstract::Transforming acidic coiled-coil protein 3 (TACC3) is a member of the TACC family, essential for mitotic spindle dynamics and centrosome integrity during mitosis. Mounting evidence suggests that deregulation of TACC3 is associated with various types of human cancer. However, the molecular mechanisms by which TACC3 cont...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2013.01.013

    authors: Ha GH,Park JS,Breuer EK

    更新日期:2013-05-10 00:00:00

  • Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma.

    abstract::EGFR polymorphisms have not been thoroughly evaluated for association with head and neck squamous cell carcinoma (HNSCC) risk. We genotyped 578 HNSCC patients and 588 cancer-free controls for 60 EGFR single nucleotide polymorphisms (SNPs) and tested associations with HNSCC risk. EGFR intronic SNPs rs12535536, rs207511...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2014.12.008

    authors: Fung C,Zhou P,Joyce S,Trent K,Yuan JM,Grandis JR,Weissfeld JL,Romkes M,Weeks DE,Egloff AM

    更新日期:2015-02-28 00:00:00

  • Dysfunction of natural killer cells in patients with transitional cell carcinoma.

    abstract::Previous studies had established that transforming growth factor-beta1 (TGF-beta1) is highly expressed in bladder tumor, facilitating progression and spreading of the cancerous cells. Here, we report that both the number and the cytotoxic function of natural killer (NK) cells are decreased in patients with superficial...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2009.09.019

    authors: Lin CT,Yu MT,Li C,Ho YC,Shen CH,Liu DW,Chang DC,Wu SF

    更新日期:2010-05-01 00:00:00

  • MicroRNA-135b acts as a tumor promoter by targeting the hypoxia-inducible factor pathway in genetically defined mouse model of head and neck squamous cell carcinoma.

    abstract::Here in, we investigated the mechanism underlying overexpression of miR-135b in the human head and neck squamous cell carcinoma (HNSCC) cell lines and in the HNSCC mouse model. Exogenous expression of miR-135b in these cell lines increased cell proliferation, migration, and colony formation. Gene silencing analysis re...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2013.01.003

    authors: Zhang L,Sun ZJ,Bian Y,Kulkarni AB

    更新日期:2013-05-01 00:00:00

  • Histone deacetylase inhibitors that target tubulin.

    abstract::Epigenetics is defined as heritable changes in gene expression that occur without changes in DNA sequence. Major mechanisms of epigenetics are post-translational histone modifications such as reversible acetylation. Histone deacetylases (HDACs) maintain the acetylation level of histones but also act on non-histone sub...

    journal_title:Cancer letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.canlet.2009.01.040

    authors: Schemies J,Sippl W,Jung M

    更新日期:2009-08-08 00:00:00

  • Comparative metabolism and macromolecular binding of benzo[a]pyrene in explant cultures of human bladder, skin, bronchus and esophagus from eight individuals.

    abstract::Benzo[a]pyrene (B[a]P) metabolism and macromolecular binding have been studied in explants from 4 tissues, bladder, skin, bronchus and esophagus from 8 donors sampled within 4 h after death. Explants were incubated with [3H]benzo[a]pyrene for 24 h, then the metabolites extracted and analyzed by high-pressure liquid ch...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(83)90112-x

    authors: Selkirk JK,Nikbakht A,Stoner GD

    更新日期:1983-02-01 00:00:00

  • Emerging next-generation sequencing-based discoveries for targeted osteosarcoma therapy.

    abstract::Osteosarcoma (OS) is the most common primary bone malignancy and is frequently lethal via metastasis to the lung. While surgical techniques and adjuvant chemotherapies have emerged to combat this deadly cancer, the 5-year survival rate has plateaued over the past four decades. Therapeutic progress has been notably poo...

    journal_title:Cancer letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.canlet.2020.01.020

    authors: Zhao J,Dean DC,Hornicek FJ,Yu X,Duan Z

    更新日期:2020-04-01 00:00:00

  • Alanine metabolism in rats bearing the Yoshida AH-130 ascites hepatoma.

    abstract::Rats bearing the Yoshida AH-130 ascites hepatoma, a cachectic rat tumour, showed signs of important muscle wasting with reduced muscle weights. This phenomenon was associated with a decreased rate of in vivo alanine oxidation as measured by the production of 14CO2 from [U-14C]alanine intragastrically administered. It ...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(94)90212-7

    authors: García-Martínez C,López-Soriano FJ,Argilés JM

    更新日期:1994-12-09 00:00:00

  • Induction of cytogenetic adaptive response of mouse bone marrow cells to radiation by therapeutic doses of bleomycin sulfate and actinomycin D as assayed by the micronucleus test.

    abstract::An in vivo micronucleus assay using bone marrow cells of Syrian albino male mice for identifying the possibility of induction of adaptive response to various doses of radiation following treatment with chemotherapeutics is described. Single doses of bleomycin sulfate (BLM-S) at 300 micrograms/kg and actinomycin-D (ACT...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(94)90043-4

    authors: Mozdarani H,Saberi AH

    更新日期:1994-04-01 00:00:00

  • Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets.

    abstract::Cucurbitacin B (CuB), has recently emerged as a potent anticancer agent; however, its efficacy in non-small-cell lung cancer (NSCLC) and the mechanism(s) initiating its biological effects remain largely unclear. In this study, CuB potently suppressed the growth of four NSCLC cells (H1299, A549, HCC-827 and H661) in vi...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2013.01.008

    authors: Kausar H,Munagala R,Bansal SS,Aqil F,Vadhanam MV,Gupta RC

    更新日期:2013-05-10 00:00:00

  • LYRM2 directly regulates complex I activity to support tumor growth in colorectal cancer by oxidative phosphorylation.

    abstract::Oxidative phosphorylation (OXPHOS) in cancer has attracted a considerable attention in the past decades, and accumulated evidence has suggested that it plays an important role in tumor proliferation, metastasis and drug resistance. However, the mechanisms involved in these effects are still ambiguous to date. In this ...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2019.04.021

    authors: Huang Q,Chen Z,Cheng P,Jiang Z,Wang Z,Huang Y,Yang C,Pan J,Qiu F,Huang J

    更新日期:2019-07-28 00:00:00

  • Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration.

    abstract::Telomerase activity (TA) and telomerase reverse transcriptase (rTERT) were investigated in Sprague-Dawley rats, killed at 6 and 12 h, and 1, 2, 3, 7, and 14 days after 90% pancreatectomy (px), by TRAPeze enzyme-linked immunosorbent assay telomerase detection and reverse transcriptase-polymerase chain reaction. TA incr...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3835(02)00320-8

    authors: Oh BK,Seong JK,Lee JE,Chae KJ,Roh KJ,Park C,Park YN

    更新日期:2002-12-01 00:00:00

  • A selective cyclin-dependent kinase 4, 6 dual inhibitor, Ribociclib (LEE011) inhibits cell proliferation and induces apoptosis in aggressive thyroid cancer.

    abstract::The RB-E2F1 pathway is an important mechanism of cell-cycle control, and deregulation of this pathway is one of the key factors contributing to tumorigenesis. Cyclin-dependent kinases (CDKs) and Cyclin D have been known to increase in aggressive thyroid cancer. However, there has been no study to investigate effects o...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2017.12.037

    authors: Lee HJ,Lee WK,Kang CW,Ku CR,Cho YH,Lee EJ

    更新日期:2018-03-28 00:00:00

  • Phorbol ester activation of epidermal protein kinase C from tumor promotion sensitive and resistant mouse strains.

    abstract::Calcium-stimulated, phospholipid dependent protein kinase C activity was found in cytosolic extracts of the epidermis of SENCAR, C57BL/6 and Ha/ICR mice. The enzymes were partially purified by DEAE-cellulose chromatography. There were no significant differences between the 3 strains in basal protein kinase C activity....

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(85)90161-2

    authors: Garte SJ,Edinger F,Mufson RA

    更新日期:1985-11-01 00:00:00

  • Potent antitumor activity of zoledronic acid-induced Vγ9Vδ2 T cells against primary effusion lymphoma.

    abstract::Primary effusion lymphoma (PEL) is a subtype of aggressive and resistant non-Hodgkin lymphoma that occurs predominantly in patients with advanced AIDS. In this study, we examined the antitumor activity of zoledronic acid (Zol)-induced Vγ9Vδ2 T cells against PEL cells in vitro and in vivo. Vγ9Vδ2 T cells recognized end...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2012.12.021

    authors: Goto H,Matsuda K,Srikoon P,Kariya R,Hattori S,Taura M,Katano H,Okada S

    更新日期:2013-05-01 00:00:00

  • SDHC-related deficiency of SDH complex activity promotes growth and metastasis of hepatocellular carcinoma via ROS/NFκB signaling.

    abstract::Succinate dehydrogenase is a heterotetrameric complex comprising four nuclear-encoded subunits, catalyzes the oxidation of succinate to fumarate in the tricarboxylic acid cycle. A subset of cancers have been found to be associated with mutations in the four SDH genes. However, the functional roles of the SDH complex i...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2019.07.001

    authors: Li J,Liang N,Long X,Zhao J,Yang J,Du X,Yang T,Yuan P,Huang X,Zhang J,He X,Xing J

    更新日期:2019-10-01 00:00:00

  • Src inhibitor dasatinib inhibits growth of breast cancer cells by modulating EGFR signaling.

    abstract::EGF-receptor family members (EGFRs) as well as c-Src are over expressed in approximately 70% of breast cancer, and in most of the tumors c-Src is co-over expressed with at least one of the EGFRs, suggesting that they may interact functionally and play a role in the development and progression of the malignancy. We hyp...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2009.03.035

    authors: Nautiyal J,Majumder P,Patel BB,Lee FY,Majumdar AP

    更新日期:2009-10-08 00:00:00

  • Effects of eicosanoid metabolism inhibitors on growth of a human gastric tumour cell line (HGT).

    abstract::HGT cells are a human gastric cell line derived from a tumour of the stomach. We have investigated the effects of lipoxygenase and cyclooxygenase metabolism inhibitors on HGT cell proliferation, on fatty acid composition of HGT cells and on the incorporation and distribution of arachidonic acid (AA) in HGT lipids. The...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/0304-3835(93)90189-g

    authors: Denizot Y,Najid A,Rigaud M

    更新日期:1993-09-15 00:00:00

  • Intraperitoneal injection of adenovirus expressing antisense K-ras RNA suppresses peritoneal dissemination of hamster syngeneic pancreatic cancer without systemic toxicity.

    abstract::We examined the antitumor effect and safety of the adenovirus-mediated expression of antisense K-ras RNA in two peritoneal dissemination models of pancreatic cancer. First, we found that the infection of an adenovirus vector expressing antisense human K-ras RNA (AxCA-AS) induced significant apoptosis in vitro in human...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2004.08.015

    authors: Miura Y,Ohnami S,Yoshida K,Ohashi M,Nakano M,Ohnami S,Fukuhara M,Yanagi K,Matsushita A,Uchida E,Asaka M,Yoshida T,Aoki K

    更新日期:2005-01-31 00:00:00

  • Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing.

    abstract::Expression of the MUC2 gene is controlled by the methylation of CpG sites in the promoter region, but the detailed methylation status of this region has yet to be reported. We have mapped the complete methylation status of the MUC2 promoter from position -1989 to position +288 upstream, a region that contains 59 CpG s...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2004.11.058

    authors: Hamada T,Goto M,Tsutsumida H,Nomoto M,Higashi M,Sugai T,Nakamura S,Yonezawa S

    更新日期:2005-09-28 00:00:00

  • Competitive uptake of porphyrin and LDL via the LDL receptor in glioma cell lines: flow cytometric analysis.

    abstract::We examined the simultaneous uptake of porphyrin and (LDL) by four established cell lines of glioma and normal fibroblasts using flow cytometry (FCM). The results indicated porphyrin and LDL showed competitive conjugation with the LDL receptor. These results support the theory of the porphyrin uptake via the LDL recep...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3835(00)00717-5

    authors: Shibata Y,Matsumura A,Yoshida F,Yamamoto T,Nakai K,Nose T,Sakata I,Nakajima S

    更新日期:2001-05-10 00:00:00

  • NFYB-induced high expression of E2F1 contributes to oxaliplatin resistance in colorectal cancer via the enhancement of CHK1 signaling.

    abstract::As a third-generation platinum drug, oxaliplatin has been widely applied in colorectal cancer (CRC); however, acquired resistance to oxaliplatin has become a major obstacle. In the present study, we found that the nuclear transcription factor Y subunit beta (NFYB) and E2F transcription factor 1 (E2F1) expression level...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2017.11.040

    authors: Fang Z,Gong C,Yu S,Zhou W,Hassan W,Li H,Wang X,Hu Y,Gu K,Chen X,Hong B,Bao Y,Chen X,Zhang X,Liu H

    更新日期:2018-02-28 00:00:00

  • Inhibition of NMU-induced mammary tumorigenesis by dietary soy.

    abstract::We previously demonstrated that female Sprague-Dawley rats fed AIN-93G diets containing soy protein isolate (SPI+) had lower DMBA-induced mammary tumor incidence than those fed diets containing casein (CAS), due partly to altered Phase I metabolism with soy. Here, we evaluated the tumor protective effects of these sam...

    journal_title:Cancer letters

    pub_type: 杂志文章

    doi:10.1016/j.canlet.2004.11.009

    authors: Simmen RC,Eason RR,Till SR,Chatman L Jr,Velarde MC,Geng Y,Korourian S,Badger TM

    更新日期:2005-06-16 00:00:00