Protective effect of dexpanthenol on ischemia-reperfusion-induced renal injury in rats.

abstract：BACKGROUND/AIMS:The role of COX-2 for renal function during renal development, for physiology and pathophysiology of renal diseases and the side effects of available COX-2 inhibitors, has gained increasing interest. We aimed therefore to review the respective role of renal COX-2. METHODS:Review of relevant recent publ...

journal_title：Kidney & blood pressure research

authors： Krämer BK,Kammerl MC,Kömhoff M

更新日期：2004-01-01 00:00:00

abstract：:Pravastatin is a potent inhibitor of HMG-CoA reductase and is effective in lowering serum lipid levels. Recent studies have shown that pravastatin also reduces the oxidative modification of low-density lipoprotein (LDL). To determine whether pravastatin has a direct effect on glomerular mesangial cells, we have measur...

journal_title：Kidney & blood pressure research

authors： Chen HC,Guh JY,Shin SJ,Tomino Y,Lai YH

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Fatty acid-bearing albumin [FA(+) albumin] exerts more deleterious effects in tubular cells than albumin alone. We investigated the effect of FA(+) albumin on the vascular cell adhesion molecule-1 (VCAM-1) expression and elucidated the underlying signaling pathways. We further examined the effect of L-carnit...

journal_title：Kidney & blood pressure research

authors： Baek JE,Yang WS,Chang JW,Kim SB,Park SK,Park JS,Lee SK

更新日期：2010-01-01 00:00:00

abstract：:The German Collaborative Glomerulonephritis Therapy Study, which celebrated its 10th anniversary in 1996, has collected data on more than 1,000 patients with biopsy-proven glomerulonephritis. 929 patients could be evaluated and 500 were treated according to at least one of various protocols developed for a randomized ...

journal_title：Kidney & blood pressure research

authors： Risler T,Braun N,Bach D,Fünfstück R,Grabensee B,Grupp C,Haufe C,Heering P,Keller F,Krämer B,Müller GA,Schollmeyer P,Stein G,Zäuner I

更新日期：1996-01-01 00:00:00

abstract：:To clarify whether the ovaries have a potential to attenuate the aggravating effect of testosterone (T) on glomerular injury, we investigated the effect of T in female rats with or without ovaries, using Adriamycin (ADR)-induced nephropathy in female Sprague-Dawley rats. Group 1 consisted of female control rats, group...

journal_title：Kidney & blood pressure research

authors： Sakemi T,Ohtsuka N,Tomiyoshi Y,Morito F

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:Lowering dialysate temperature to increase intradialytic hemodynamic stability may interfere with the ultrafiltration-dependent intradialytic autonomic cardiovascular regulation. The present study aimed to investigate hemodynamic and autonomic responses depending on dialysate temperature and the presenc...

journal_title：Kidney & blood pressure research

authors： Zitt E,Neyer U,Meusburger E,Tiefenthaler M,Kotanko P,Mayer G,Rosenkranz AR

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Additional validation study was warranted to confirm the clinical significance of C score, which was recently added to the Oxford classification for immunoglobulin A nephropathy (IgAN). METHODS:We performed a multicenter retrospective cohort study in four hospitals in Korea. Patients who had biopsied g...

journal_title：Kidney & blood pressure research

authors： Park S,Baek CH,Park SK,Kang HG,Hyun HS,Park E,Han SH,Ryu DR,Kim DK,Oh KH,Joo KW,Kim YS,Moon KC,Chin HJ,Lee H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:IgA nephropathy is associated with aberrant O-glycosylation of IgA1, which is recognized by autoantibodies leading to the formation of circulating immune complexes. Some of them, after deposition into kidney mesangium, trigger glomerular injury. In patients with active disease nonresponding to angiotens...

journal_title：Kidney & blood pressure research

authors： Kosztyu P,Hill M,Jemelkova J,Czernekova L,Kafkova LR,Hruby M,Matousovic K,Vondrak K,Zadrazil J,Sterzl I,Mestecky J,Raska M

更新日期：2018-01-01 00:00:00

abstract：:The nonmetabolizable glucose analogue [(3)H]-2-deoxy-D-glucose ((3)H-2DG) was used to study glucose transport in cultured rat podocytes. Intracellular accumulation of (3)H-2DG was linear up to 20 min and was inhibited by cytochalasin B (80% inhibition) and by phlorizin (20% inhibition). Pretreatment with insulin stimu...

journal_title：Kidney & blood pressure research

authors： Lewko B,Bryl E,Witkowski JM,Latawiec E,Gołos M,Endlich N,Hähnel B,Koksch C,Angielski S,Kriz W,Stepinski J

更新日期：2005-01-01 00:00:00

abstract：:Angiotensin-(1-7), (Ang-(1-7)), a metabolite of Ang II and /or Ang I, was infused into the renal artery (i.r.a) of anesthetized dogs in order to demonstrate its possible direct renal action. The dose administered, 15 Ig/kg BW/min in isotonic saline (0.072 ml/kg BW/min) throughout the experiment, did not influence the ...

journal_title：Kidney & blood pressure research

authors： Heller J,Kramer HJ,Malý J,Cervenka L,Horácek V

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:OSR1 (oxidative-stress-responsive kinase 1) participates in the regulation of renal tubular ion transport, cell volume and blood pressure. Whether OSR1 contributes to the regulation of organic solute transport remained; however, elusive. The present study thus explored the OSR1 sensitivity of the peptid...

journal_title：Kidney & blood pressure research

authors： Warsi J,Elvira B,Bissinger R,Shumilina E,Hosseinzadeh Z,Lang F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Endothelial-to-mesenchymal transition (EndMT) of glomerular endothelial cells (GEnCs) can induce albuminuria in diabetic nephropathy. Melatonin attenuates diabetic nephropathy, but its role and mechanism in EndMT of GEnCs in diabetic nephropathy remain unknown. METHODS:The effect of melatonin on EndMT ...

journal_title：Kidney & blood pressure research

authors： Liu F,Zhang S,Xu R,Gao S,Yin J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:We previously showed that urine and serum Angiopoietin-2 (Ang-2) levels increased significantly with the degree of albuminuria in diabetes patients, but the reasons remain unclear. Consequently we aimed to determine whether there was an association between Ang-2, inflammatory cytokines (TNF-α and IL-18)...

journal_title：Kidney & blood pressure research

authors： He FF,Li HQ,Huang QX,Wang QY,Jiang HJ,Chen S,Su H,Zhang C,Wang YM

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:In uremic patients coronary surgery and the entire perioperative management is demanding. METHODS:We analyzed retrospectively data from all patients requiring chronic hemodialysis who under went coronary artery bypass grafting (CABG) between January 1 2001 and December 31 2004 at the Deutsches Herzzentrum B...

journal_title：Kidney & blood pressure research

authors： Krabatsch T,Yeter R,Hetzer R

更新日期：2005-01-01 00:00:00

abstract：:Although primary cilia are increasingly recognized to play sensory roles in several cellular systems, their role in vascular smooth muscle cells (VSMCs) has not been defined. We examined in situ position/orientation of primary cilia and ciliary proteins in VSMCs and tested the hypothesis that primary cilia of VSMCs ex...

journal_title：Kidney & blood pressure research

authors： Lu CJ,Du H,Wu J,Jansen DA,Jordan KL,Xu N,Sieck GC,Qian Q

更新日期：2008-01-01 00:00:00

abstract：AIMS:The aim of this study was to screen several novel genes associated with renal cell carcinoma (RCC), and analyze the gene functions and signal pathways which were critical to RCCs with DNA microarray. METHODS:The gene expression profile of GSE781 was downloaded from Gene Expression Omnibus database, including 9 RC...

journal_title：Kidney & blood pressure research

authors： Li W,Zhu W,Che J,Sun W,Liu M,Peng B,Zheng J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Metabolic acidosis may be diagnosed as chronic (cMA) if it persists for at least 5 days, although an exact definition has not been provided by any guidelines yet. The most common cause is CKD; numerous less-known diseases can also account for cMA. SUMMARY:In recent years, CKD-associated cMA has been propose...

journal_title：Kidney & blood pressure research

authors： Patschan D,Patschan S,Ritter O

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:The kidney plays a critical role in the control of blood pressure and its elevation in salt-induced hypertension. Mitochondrial dysfunction, especially in energy metabolism, has been associated with hypertension. Here, we aimed to investigate mitochondrial function and metabolic features in renal mitoch...

journal_title：Kidney & blood pressure research

authors： Wang Z,Sun Q,Sun N,Liang M,Tian Z

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIM:Calcifications of large arteries are frequent in chronic kidney disease (CKD) and may contribute to the high cardiovascular risk in this population. The aim of this study was to examine whether abdominal aortic calcification volume (AACV) was a predictor of the rate of decline in glomerular filtration ra...

journal_title：Kidney & blood pressure research

authors： Jansson H,Saeed A,Svensson MK,Finnved K,Hellström M,Guron G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Though the association between microalbuminuria (MA) and inflammatory markers has been studied, the possible gender differences in these associations have not yet been analyzed. Our study aims to analyze the role of gender in the associations of MA and inflammatory markers. METHODS:1,060 hypertensive patien...

journal_title：Kidney & blood pressure research

authors： Shantha GP,Kumar AA,Bharadhi MK,Arthur P

更新日期：2009-01-01 00:00:00

abstract：:Recently, Chlamydia pneumoniae is the microorganism frequently implicated in the infection-based inflammatory atherogenous hypothesis. Although in vitro experimental data and initial sero-epidemiologic, pathology-based studies and antibiotic trials supported this interesting hypothesis, later data are conflicting. Som...

journal_title：Kidney & blood pressure research

authors： Tsirpanlis G

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:To date, there is no imaging technique to assess tubular function in vivo. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) measures tissue oxygenation based on the transverse relaxation rate (R2*). The present study investigates whether BOLD MRI can assess tubular function using a tub...

journal_title：Kidney & blood pressure research

authors： Bauer F,Wald J,Bauer FJ,Dahlkamp LM,Seibert FS,Pagonas N,Gedat E,Babel N,Zidek W,von Bodman C,Noldus J,Liermann D,Westhoff TH

更新日期：2017-01-01 00:00:00

abstract：:Progressive renal disease poses an increasing problem for the medical community. Though the causes of end-stage renal failure are multiple, the histologic pictures of chronic renal disease are remarkably similar being characterized by interstitial infiltration, fibrosis, tubular atrophy and dilatation. This similarity...

journal_title：Kidney & blood pressure research

authors： Strutz F,Müller GA

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND AIM:Cinacalcet effectively reduces calcium in patients with persistent hyperparathyroidism (HPT) after kidney transplantation. We aimed to assess the association of cinacalcet with a decrease in renal function based on a meta-analysis of observational studies in kidney transplant patients with persistent...

journal_title：Kidney & blood pressure research

authors： Henschkowski J,Bischoff-Ferrari HA,Wüthrich RP,Serra AL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Post-transplant hypertension is highly prevalent in renal transplant recipients and is a risk factor for graft loss, cardiovascular disease and death. Glucocorticoid is used to prevent rejection, but simultaneously increases the risk of post-transplant hypertension. The glucocorticoid-induced transcript...

journal_title：Kidney & blood pressure research

authors： Hamada AM,Yamamoto I,Nakada Y,Kobayashi A,Koike Y,Miki J,Yamada H,Tanno Y,Ohkido I,Tsuboi N,Yamamoto H,Urashima M,Yokoo T

更新日期：2017-01-01 00:00:00

abstract：AIMS AND METHODS:Our aim was to evaluate the antihypertensive efficacy and tolerability of angiotensin II type 1 (AT1) receptor antagonists. Valsartan or candesartan cilexetil was administered to 11 dialysis patients with elevated blood pressure. The patients (6 male, 5 female; mean age +/- SD 61+/-11 years) were on re...

journal_title：Kidney & blood pressure research

authors： Tepel M,van der Giet M,Zidek W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:Aortic arch calcification (AoAC) is frequently detected in maintenance hemodialysis (MHD) patients and is associated with cardiovascular and all-cause mortality. We investigated the factors associated with AoAC and analyzed the relationship between the factors including bone-derived biomarkers and AoAC....

journal_title：Kidney & blood pressure research

authors： Nitta K,Hanafusa N,Okazaki M,Komatsu M,Kawaguchi H,Tsuchiya K

更新日期：2018-01-01 00:00:00

abstract：:Since reports of the first data on cytokines in renal diseases about 10 years ago, the field has seen an explosive growth over the last decade. It is now realized that cytokines can be synthesized by many different types of cells, including glomerular cells, upon adequate stimulation and exert a wide range of actions ...

journal_title：Kidney & blood pressure research

authors： Ostendorf T,Burg M,Floege J

更新日期：1996-01-01 00:00:00

abstract：:In the pathogenesis of anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitis, T cell contribution is indicated by T cell-dependent ANCA production combined with the presence of T cells in inflammatory infiltrates. However, the exact pathogenic role of T cells in ANCA-associated vasculitis remains to be det...

journal_title：Kidney & blood pressure research

authors： Sanders JS,Stegeman CA,Kallenberg CG

更新日期：2003-01-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the influence of cycle exercise during hemodialysis (HD) on patients' physical proficiency, muscle strength, quality of life and selected laboratory parameters. PATIENTS AND METHODS:In a group of 29 (15 female, 14 male) HD patients (age 64.2 ± 13.1 years), 3 months of c...

journal_title：Kidney & blood pressure research

authors： Gołębiowski T,Kusztal M,Weyde W,Dziubek W,Woźniewski M,Madziarska K,Krajewska M,Letachowicz K,Strempska B,Klinger M

更新日期：2012-01-01 00:00:00