Forskolin induced increase in spontaneous activity of auditory brainstem neurons is comparable to acoustic stimulus evoked responses.

abstract：:Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60-70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce oxidative stress, and prevent diabetes and non-alcoholic fatty liver disease. However, it is unclear whether Spirulina maxima 70% ethanol extra...

journal_title：Neuroscience letters

authors： Koh EJ,Kim KJ,Choi J,Kang DH,Lee BY

更新日期：2018-04-23 00:00:00

abstract：:Recently, we reported that voluntary resistance wheel running with a resistance of 30% of body weight (RWR), which produces shorter distances but higher work levels, enhances spatial memory associated with hippocampal brain-derived neurotrophic factor (BDNF) signaling compared to wheel running without a load (WR) [17]...

journal_title：Neuroscience letters

authors： Lee MC,Inoue K,Okamoto M,Liu YF,Matsui T,Yook JS,Soya H

更新日期：2013-03-14 00:00:00

abstract：:The neuronal number and nucleolar volume of the magnocellular population of the basal nucleus of Meynert in 6 patients with progressive supranuclear palsy (PSP) - one associated with Alzheimer's disease - were compared with those of 5 controls. In the 5 typical PSP cases, an age-dependent neuronal loss was demonstrate...

journal_title：Neuroscience letters

authors： Tagliavini F,Pilleri G,Bouras C,Constantinidis J

更新日期：1984-01-27 00:00:00

abstract：:The putative anti-addiction alkaloid ibogaine and its principal metabolite 12-hydroxyibogamine appear to act at the (+)-5 methyl-10,11,dihydro-5H- dibenzo[a,d]cycloheten-5-10-imine maleate (MK-801) binding site in the N-methyl-D-aspartate (NMDA)-receptor cation channel. This conclusion is based on findings that both c...

journal_title：Neuroscience letters

authors： Mash DC,Staley JK,Pablo JP,Holohean AM,Hackman JC,Davidoff RA

更新日期：1995-06-02 00:00:00

abstract：:To light illumination retinal amacrine cells respond with graded depolarization accompanied by a spike discharge. It has been assumed that the graded depolarization is produced solely by the excitatory synaptic inputs from bipolar cells. Here we demonstrate that a tetrodotoxin (TTX)-sensitive persistent current also c...

journal_title：Neuroscience letters

authors： Watanabe S,Satoh H,Koizumi A,Takayanagi T,Kaneko A

更新日期：2000-01-07 00:00:00

abstract：:Bilateral injections of the GABA(A) agonist muscimol into the lateral parabrachial nucleus (LPBN) disrupt satiety and induce strong ingestion of water and 0.3M NaCl in fluid-replete rats by mechanisms not completely clear. In the present study, we investigated the effects of the blockade of central muscarinic choliner...

journal_title：Neuroscience letters

authors： Asnar DS,Roncari CF,De Luca LA Jr,de Paula PM,Colombari DS,Menani JV

更新日期：2013-02-08 00:00:00

abstract：:We present results of homozygosity mapping in two siblings affected with early onset Parkinson's disease (EOPD) and mutation screening of ATP13A2 in these and other Iranian EOPD patients. Genome-wide SNP homozygosity analysis revealed linkage to a locus that included ATP13A2, and sequencing of the gene revealed a nove...

journal_title：Neuroscience letters

authors： Malakouti-Nejad M,Shahidi GA,Rohani M,Shojaee SM,Hashemi M,Klotzle B,Fan JB,Elahi E

更新日期：2014-08-08 00:00:00

abstract：:The distribution of premotor neurons projecting to motor nuclei of both the VIIth (VII) and XIIth (XII) nerves was examined in the pontomedullary reticular formation (RF) of the rat by using retrograde double labeling. After injection of two different tracers in the VII and the XII, most of the double labeled neurons ...

journal_title：Neuroscience letters

authors： Dauvergne C,Pinganaud G,Buisseret P,Buisseret-Delmas C,Zerari-Mailly F

更新日期：2001-09-28 00:00:00

abstract：:Many gene expression studies have examined postmortem brain tissues of patients with schizophrenia. However, only a few expression studies of the genes identified in genome-wide association study (GWAS) have been published to date. We measured the expression levels of the genes identified in GWAS (ZNF804A, OPCML, RPGR...

journal_title：Neuroscience letters

authors： Umeda-Yano S,Hashimoto R,Yamamori H,Weickert CS,Yasuda Y,Ohi K,Fujimoto M,Ito A,Takeda M

更新日期：2014-05-07 00:00:00

abstract：:Apoptosis is thought to play a role in neuronal pathology in schizophrenia. Recently, the GSN gene was reported to have anti-apoptotic properties. In a genome-wide expression analysis on schizophrenia, GSN was also found to be significantly down-regulated in schizophrenia. All the hints suggest that GSN is a novel can...

journal_title：Neuroscience letters

authors： Xi ZR,Qin W,Yang YF,He G,Gao SH,Ren MS,Peng YW,Zhang Z,He L

更新日期：2004-12-06 00:00:00

abstract：:Afferent fibers ending in nerve-end neuromas generate spontaneous impulse discharge which has been implicated as a cause of paraesthesias and pain following peripheral nerve injury in man. We now show in rats that the anticonvulsant drug phenytoin (PT), applied systemically or topically onto desheathed neuromas, suppr...

journal_title：Neuroscience letters

authors： Yaari Y,Devor M

更新日期：1985-07-04 00:00:00

abstract：:Miyoshi myopathy (MM) is an autosomal recessive distal muscular dystrophy caused by mutations in the dysferlin gene (DYSF), a 150-kb gene on chromosome 2p13 that contains 55 coding exons. Many patients with MM harbour mutations in the DYSF gene, and most of these mutations are inherited from the patients' parents. Rec...

journal_title：Neuroscience letters

authors： Hu YY,Lian YJ,Xu HL,Zheng YK,Li CF,Zhang JW,Yan SP

更新日期：2018-01-18 00:00:00

abstract：:Hippocampal choline acetyltransferase was reduced by 89% in rats two weeks after electrolytic lesion of the septum. The hippocampal concentrations of somatostatin (SOM)-14, SOM-28 and high-molecular-weight SOM were unaltered, suggesting that the activity of hippocampal SOM neurones is not influenced by cholinergic aff...

journal_title：Neuroscience letters

authors： Pierotti AR,Simpson J

更新日期：1986-01-30 00:00:00

abstract：:The phenotype of neurotrophin-3 (NT-3) null mutant mice is characterized by sensory ataxia and early postnatal death. Previous analysis revealed a severe depletion of peripheral sensory, sympathetic and parasympathetic neurons. Most of the deficits are established early during embryonic development. Whereas absence of...

journal_title：Neuroscience letters

authors： Barski JJ,Helbig C,Meyer M

更新日期：2011-09-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is a nosological entity proposed as an intermediate state between normal aging and dementia. MCI seems to represent an early stage of Alzheimer's disease (AD) and there is a great interest in the relationship between MCI and the progression to AD. Some studies have demonstrated an accum...

journal_title：Neuroscience letters

authors： Padurariu M,Ciobica A,Hritcu L,Stoica B,Bild W,Stefanescu C

更新日期：2010-01-18 00:00:00

abstract：:The aim of the present study was to determine if pre-exposure to high doses of cocaine can subsequently alter the rewarding effects of this drug. Adult male mice received a pretreatment of physiological saline, or 12.5 or 25 mg/kg of cocaine (one injection a day for five days). After an interval of six days without in...

journal_title：Neuroscience letters

authors： Manzanedo C,García-Pardo MP,Rodríguez-Arias M,Miñarro J,Aguilar MA

更新日期：2012-05-10 00:00:00

abstract：:The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The proces...

journal_title：Neuroscience letters

authors： Nishibori M,Ohtsuka A,Kawabata M,Nakaya N,Murakami T,Saeki K

更新日期：1995-11-17 00:00:00

abstract：:The excitotoxic cell death and the release of gamma-amino-butyric acid (GABA) evoked by excitatory amino acids (EAAs) were comparatively examined in rat cortical sister cultures grown in serum-free (N2) and serum-supplemented (SSM) media. Cell death was induced by 24 h exposure to 1 mM N-methyl-D-aspartate (NMDA), alp...

journal_title：Neuroscience letters

authors： Erdö SL,Cai N,Lakics V

更新日期：1993-04-02 00:00:00

abstract：:CREATE (Consider, Read, Elucidate hypotheses, Analyze and interpret data, Think of the next Experiment) is a pedagogical approach for teaching and learning science through the rigorous analysis of primary scientific literature. This mini-review focuses on the tools, assignments, and in-class activities by which this s...

journal_title：Neuroscience letters

authors： Pugh-Bernard A,Kenyon KL

更新日期：2021-01-18 00:00:00

abstract：:Monotherapy with antibodies to tumor necrosis factor-alpha (TNF) or interleukin-1 receptor 1 (IL-1R1) reduces hyperalgesia in an animal model of painful neuropathy. Here we investigated whether combined therapy with epineurial anti-TNF and anti-IL-1R1 antibodies produces a further advantage. C57BL/6 mice with a chroni...

journal_title：Neuroscience letters

authors： Schäfers M,Brinkhoff J,Neukirchen S,Marziniak M,Sommer C

更新日期：2001-09-14 00:00:00

abstract：:Although a linear correlation between oscillatory activities in the right and left motor cortices during movements has been shown in monkeys, there has been a debate whether scalp-recorded EEG coherence in human reflects a similar association. By applying partial coherence analysis, we demonstrated that interhemispher...

journal_title：Neuroscience letters

authors： Mima T,Matsuoka T,Hallett M

更新日期：2000-06-23 00:00:00

abstract：:Effects of conceptual fusion on episodic associative retrieval were examined. Subjects attempted to fuse sequentially displayed (800 ms offset) word pairs; pairs subjects were unable to fuse were instead considered associated by juxtaposition. Next, dense-array event-related potentials (ERPs) were recorded while the p...

journal_title：Neuroscience letters

authors： Kounios J,Bachman P,Casasanto D,Grossman M,Smith RW,Yang W

更新日期：2003-07-24 00:00:00

abstract：:The deposition of amyloid beta protein (Abeta), a proteolytic cleavage product of amyloid precursor protein (APP), is an invariable pathological feature of the Alzheimer's disease brain, while APP gene is widely expressed in all neuronal and non-neuronal tissues with the highest levels of expression in the brain, and ...

journal_title：Neuroscience letters

authors： Tsuzuki K,Fukatsu R,Yamaguchi H,Tateno M,Imai K,Fujii N,Yamauchi T

更新日期：2000-03-10 00:00:00

abstract：:A paired-pulse stimulus protocol was used to measure angular bundle to dentate gyrus paired-pulse inhibition in rats before and after the occurrence of 36 or 72 seizures elicited from the contralateral CA3 region. The seizures showed progressive lengthening. There was a moderate increase in paired-pulse depression 1 h...

journal_title：Neuroscience letters

authors： Stringer JL,Lothman EW

更新日期：1989-10-23 00:00:00

abstract：:Localizations of thalamic relay neurons of vibrissae, common fur of the muzzle and head, as well as those projecting to the cortical vibrissal field in mice with vibrissae coagulated at birth, have been studied by retrograde transport of peroxydase. The tracer was injected in the corresponding cortical areas. In coagu...

journal_title：Neuroscience letters

authors： Verney C,Farkas-Bargeton E,Verley R

更新日期：1982-10-23 00:00:00

abstract：:The function of Merkel cells in mechanotransduction has remained controversial Single unit recordings were made from Merkel cell receptors (sinus hair type I, St I) and another slowly adapting mechanoreceptor (sinus hair type II, St II) in isolated rat sinus hairs by applying controlled mechanical displacements to the...

journal_title：Neuroscience letters

authors： Senok SS,Halata Z,Baumann KI

更新日期：1996-08-23 00:00:00

abstract：:In the adult, the dickkopf family member Dickkopf-like1 (Dkkl1) has been described as a testicular protein involved in the regulation of spermatocyte apoptosis. However, microarray studies additionally suggested that Dkkl1 regulation is involved in various tumors including high grade gliomas. Since investigations of D...

journal_title：Neuroscience letters

authors： Sibbe M,Jarowyj J

更新日期：2013-02-22 00:00:00

abstract：:Quantitative receptor autoradiography was used to study dopamine (DA) receptors in dorsal striatum and its projection regions in brains from individuals dying with Huntington's disease (HD) and controls. Heterogeneous loss of both D1 and D2 receptors was present in the striatum of early and late stage HD brains. The d...

journal_title：Neuroscience letters

authors： Richfield EK,O'Brien CF,Eskin T,Shoulson I

更新日期：1991-10-28 00:00:00

abstract：:In the present study we aimed at evaluating the prevalence and the associated clinical, neuropsychological and behavioral features of extrapyramidal symptoms in Frontotemporal Dementia (FTD) patients. Seventy-five patients fulfilling clinical criteria of FTD were consecutively enrolled. Each patient underwent clinical...

journal_title：Neuroscience letters

authors： Padovani A,Agosti C,Premi E,Bellelli G,Borroni B

更新日期：2007-07-05 00:00:00

abstract：:Noise-induced hearing loss (NIHL) has been thought to primarily involve damage to the sensory hair cells of the cochlea via mechanical and metabolic mechanisms. This study examined the effects of baicalin, baicalein, and Scutellaria baicalensis (SB) extract against NIHL in a mouse model. Mice received oral treatment w...

journal_title：Neuroscience letters

authors： Kang TH,Hong BN,Park C,Kim SY,Park R

更新日期：2010-01-29 00:00:00