Two-layer architecture using atom transfer radical polymerization for enhanced sensing and detection in complex media.

abstract：:The positive interaction of materials with tissues is an important step in regenerative medicine strategies. Hydrogels that are obtained from polysaccharides and proteins are expected to mimic the natural cartilage environment and thus provide an optimum milleu for tissue growth and regeneration. In this work, novel h...

journal_title：Biomacromolecules

authors： Silva SS,Motta A,Rodrigues MT,Pinheiro AF,Gomes ME,Mano JF,Reis RL,Migliaresi C

更新日期：2008-10-01 00:00:00

abstract：:Feasibility of using amphiphilic block copolymers composed of polylactide (PLA) and poly(ethylene oxide) (PEO) blocks for biomimetic surface modification of polylactide-based biomaterials for tissue engineering was investigated. PEO-b-PLA copolymers were deposited on the PLA surface from a solution in PEO-selective so...

journal_title：Biomacromolecules

authors： Tresohlavá E,Popelka S,Machová L,Rypácek F

更新日期：2010-01-11 00:00:00

abstract：:This work reports on the effect of CO2 at subcritical conditions and the gaseous state on the telechelic poly(epsilon-caprolactone) polymers. The tested polymers are semi-crystalline in nature and thus the effect of functional groups and their overall contribution to foaming and formation of microstructures with open-...

journal_title：Biomacromolecules

authors： Nawaby AV,Farah AA,Liao X,Pietro WJ,Day M

更新日期：2005-09-01 00:00:00

abstract：:The purpose of this study is to investigate the combined effects of oxygen plasma treatments and silver nanoparticles (Ag) on PLGA in order to modulate the surface antimicrobial properties through tunable bacteria adhesion mechanisms. PLGA nanocomposite films, produced by solvent casting with 1 wt % and 7 wt % of Ag n...

journal_title：Biomacromolecules

authors： Fortunati E,Mattioli S,Visai L,Imbriani M,Fierro JL,Kenny JM,Armentano I

更新日期：2013-03-11 00:00:00

abstract：:Effects of molecular weight (Lc) and field strength (E) on conformation of polymer chains and their density are investigated at the surface and bulk of a driven chain system in three dimensions with a Monte Carlo simulation. As the polymer chains deposit on the surface, a linear density gradient develops in low field....

journal_title：Biomacromolecules

authors： Foo GM,Pandey RB

更新日期：2000-10-01 00:00:00

abstract：:Biopolymers bearing hydrophobic side-chains, such as hydrophobically modified chitosan (hmC), can connect liposomes into a gel network via hydrophobic interactions. In this paper, we show that such liposome gels possess an attractive combination of properties for certain drug delivery applications. Their shear-thinnin...

journal_title：Biomacromolecules

authors： Lee JH,Oh H,Baxa U,Raghavan SR,Blumenthal R

更新日期：2012-10-08 00:00:00

abstract：:Gelatin microspheres are well-known for their capacity to release growth factors in a controlled manner, but gelatin microspheres do not calcify in the absence of so-called bioactive substances that induce deposition of calcium phosphate (CaP) bone mineral. This study has investigated if CaP nanocrystals can be incorp...

journal_title：Biomacromolecules

authors： Leeuwenburgh SC,Jo J,Wang H,Yamamoto M,Jansen JA,Tabata Y

更新日期：2010-10-11 00:00:00

abstract：:Biobased poly(γ-butyrolactone) (PγBL) as a fully biodegradable and bioabsorbable biomaterial has shown superior properties compared to those of other aliphatic polyesters. It is of great importance to prepare amphiphilic block copolymer containing PγBL block to make ordered nano-objects for biomedical applications suc...

journal_title：Biomacromolecules

authors： Shen Y,Zhang J,Zhao Z,Zhao N,Liu F,Li Z

更新日期：2019-01-14 00:00:00

abstract：:The stability of internally cross-linked casein micelles against disruption by urea (which disrupts hydrogen bonds and hydrophobic interactions) and trisodium citrate (which sequesters micellar calcium phosphate) was investigated. Addition of urea (0-6 mol L-1) and/or citrate (0-50 mmol L-1) progressively reduced the ...

journal_title：Biomacromolecules

authors： Huppertz T,Smiddy MA,de Kruif CG

更新日期：2007-04-01 00:00:00

abstract：:Multiblock copolymers (MBCs) are fascinating in the field of biology-polymer chemistry interfaces. Synthesizing libraries of MBCs with tailor-made functionality is challenging as it involves multiple steps. Herein, a simple synthesis, analogous to polyurethane/Michael addition reactions, has been introduced to obtain ...

journal_title：Biomacromolecules

authors： Nutan B,Kumar A,Jewrajka SK

更新日期：2020-12-14 00:00:00

abstract：:Five poly(betaine) brushes were prepared, and their resistance to blood plasma fouling was studied. Two carboxybetaines monomers were copolymerized with 2-hydroxyethyl methacrylate (HEMA) to prepare novel hydrogels. By increasing the content of the zwitterionic comonomer, a 4-fold increase in the water content could b...

journal_title：Biomacromolecules

authors： Kostina NY,Rodriguez-Emmenegger C,Houska M,Brynda E,Michálek J

更新日期：2012-12-10 00:00:00

abstract：:l-Proline is the only, out of 20 essential, amino acid that contains a cyclized substituted α-amino group (is formally an imino acid), which restricts its conformational shape. The synthesis of well-defined homo- and copolymers of l-proline has been plagued either by the low purity of the monomer or the inability of m...

journal_title：Biomacromolecules

authors： Gkikas M,Iatrou H,Thomaidis NS,Alexandridis P,Hadjichristidis N

更新日期：2011-06-13 00:00:00

abstract：:A comprehensive understanding of the mechanism by which type I collagen (Col) interacts with hydroxyapatite nanoparticles (Hap NPs) in aqueous solutions is a pivotal step for guiding the design of biologically relevant nanocomposites with controlled hierarchical structure. In this paper we use a variety of Hap NPs dif...

journal_title：Biomacromolecules

authors： Colaço E,Brouri D,Aissaoui N,Cornette P,Dupres V,Domingos RF,Lambert JF,Maisonhaute E,Kirat KE,Landoulsi J

更新日期：2019-12-09 00:00:00

abstract：:Deep eutectic solvents promoted the stabilization of the collapsed state of elastin-like recombinamers - and the subsequent formation of aggregates - upon the loss of the structural water molecules involved in hydrophobic hydration. Cryo-etch scanning electron microscopy allowed the observation of these aggregates i...

journal_title：Biomacromolecules

authors： Nardecchia S,Gutiérrez MC,Ferrer ML,Alonso M,López IM,Rodríguez-Cabello JC,del Monte F

更新日期：2012-07-09 00:00:00

abstract：:Herein we present a unique method of using dynamic cross-links, which are dynamic covalent bonding and ionic interaction, for the construction of injectable double-network (DN) hydrogels, with the objective of cell delivery for cartilage repair. Glycol chitosan and dibenzaldhyde capped poly(ethylene oxide) formed the ...

journal_title：Biomacromolecules

authors： Yan Y,Li M,Yang D,Wang Q,Liang F,Qu X,Qiu D,Yang Z

更新日期：2017-07-10 00:00:00

abstract：:This study is devoted to developing amphiphilic block polymers based on phenylborate ester, which can self-assemble to form nanoparticles, as a glucose-sensitive drug carrier. Poly(ethylene glycol)-block-poly[(2-phenylboronic esters-1,3-dioxane-5-ethyl) methylacrylate] (MPEG5000-block-PBDEMA) was fabricated with MPEG5...

journal_title：Biomacromolecules

authors： Yao Y,Zhao L,Yang J,Yang J

更新日期：2012-06-11 00:00:00

abstract：:Functionally designed elastomeric nanofiber fabrics made of the equimolar copolyester, poly(L-lactide-co-epsilon-caprolactone) (PLCL), with type I collagen or the tri-n-butylamine salt of heparin (heparin-TBA) were co-electrospun using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as a solvent. The co-electrospun fabrics (...

journal_title：Biomacromolecules

authors： Kwon IK,Matsuda T

更新日期：2005-07-01 00:00:00

abstract：:The aim of this paper is to define optimal conditions for the extraction of chitin from shrimp shells. The kinetics of both demineralization and deproteinization with, in the latter case, the role of temperature are studied. The characterization of the residual calcium and protein contents, the molecular weights, and ...

journal_title：Biomacromolecules

authors： Percot A,Viton C,Domard A

更新日期：2003-01-01 00:00:00

abstract：:The single and triple helical organization of protein chains strongly influences the mechanical properties of gelatin-based materials. A chemical method for obtaining different degrees of helical organization in gelatin is covalent functionalization, while a physical method for achieving the same goal is the variation...

journal_title：Biomacromolecules

authors： Zaupa A,Neffe AT,Pierce BF,Nöchel U,Lendlein A

更新日期：2011-01-10 00:00:00

abstract：:Biodegradable aliphatic polyesters such as poly(lactide) and poly(ε-caprolactone), largely used in tissue engineering applications, lack suitable functional groups and biological cues to enable interactions with cells. Because of the ubiquity of thiol groups in the biological environment and the pliability of thiol ch...

journal_title：Biomacromolecules

authors： Fuoco T,Finne-Wistrand A,Pappalardo D

更新日期：2016-04-11 00:00:00

abstract：:The aggregation phenomena in aqueous solutions of hydrophobically modified (HM) chitosan, containing 4 mol % of n-dodecyl side chains, were studied by viscometry and fluorescence spectroscopy with pyrene as a probe. The results are compared with those for unmodified chitosan. Surprisingly, fluorescence data reveal the...

journal_title：Biomacromolecules

authors： Philippova OE,Volkov EV,Sitnikova NL,Khokhlov AR,Desbrieres J,Rinaudo M

更新日期：2001-07-01 00:00:00

abstract：:This paper describes the synthesis and cytotoxicity of poly(anhydride esters) that are composed of several salicylate derivatives, including halogenated salicylates, aminosalicylates, salicylsalicylic acid, and thiolsalicylic acid. The incorporation of these nonsteroidal antiinflammatory drugs (NSAIDs) into a biodegra...

journal_title：Biomacromolecules

authors： Schmeltzer RC,Schmalenberg KE,Uhrich KE

更新日期：2005-01-01 00:00:00

abstract：:Electrospinning for the formation of nanoscale diameter fibers has been explored for high-performance filters and biomaterial scaffolds for vascular grafts or wound dressings. Fibers with nanoscale diameters provide benefits due to high surface area. In the present study we explore electrospinning for protein-based bi...

journal_title：Biomacromolecules

authors： Jin HJ,Fridrikh SV,Rutledge GC,Kaplan DL

更新日期：2002-11-01 00:00:00

abstract：:Biological composites are typically based on an adhesive matrix that interlocks rigid reinforcing elements in fiber composite or brick-and-mortar assemblies. In nature, the adhesive matrix is often made up of proteins, which are also interesting model systems, as they are unique among polymers in that we know how to e...

journal_title：Biomacromolecules

authors： Malho JM,Ouellet-Plamondon C,Rüggeberg M,Laaksonen P,Ikkala O,Burgert I,Linder MB

更新日期：2015-01-12 00:00:00

abstract：:The shear rheology of a microcrystalline cellulose dissolved in a 9% NaOH aqueous solution was studied in the steady and oscillatory modes. The cellulose-(9% NaOH-H(2)O) mixtures show not to be true solutions. In the dilute regime, with cellulose concentration below 1%, the rheological behavior is typical of the one o...

journal_title：Biomacromolecules

authors： Roy C,Budtova T,Navard P

更新日期：2003-03-01 00:00:00

abstract：:The need for thermosets from renewable resources is continuously increasing to find eco-friendly alternatives to petroleum-derived materials. Products obtained from biomass have shown to play an important role in this challenge. Here, we present the structural characterization of new biobased thermosets made of humins...

journal_title：Biomacromolecules

authors： Cantarutti C,Dinu R,Mija A

更新日期：2020-02-10 00:00:00

abstract：:High molecular weight trimethylene carbonate (TMC) and epsilon-caprolactone (CL) (co)polymers were synthesized. Melt pressed (co)polymer films were cross-linked by gamma irradiation (25 kGy or 50 kGy) in vacuum, yielding gel fractions of up to 70%. The effects of copolymer composition and irradiation dose on the cytot...

journal_title：Biomacromolecules

authors： Bat E,Plantinga JA,Harmsen MC,van Luyn MJ,Zhang Z,Grijpma DW,Feijen J

更新日期：2008-11-01 00:00:00

abstract：:Reductively degradable biopolymers have emerged as a unique class of smart biomedical materials. Here, a functional coupling agent, cystamine diisocyanate (CDI), was designed to offer a facile access to reductively degradable biopolymers via polycondensation with various diols. CDI was readily obtained with a decent y...

journal_title：Biomacromolecules

authors： Wang X,Zhang J,Cheng R,Meng F,Deng C,Zhong Z

更新日期：2016-03-14 00:00:00

abstract：:Although doxorubicin (Dox) has been widely used in the treatment of different types of cancer, its insufficient cellular uptake and intracellular release is still a limitation. Herein, we report an easy process for the preparation of redox-sensitive nanogels that were shown to be highly efficient in the intracellular ...

journal_title：Biomacromolecules

authors： Maciel D,Figueira P,Xiao S,Hu D,Shi X,Rodrigues J,Tomás H,Li Y

更新日期：2013-09-09 00:00:00

abstract：:Spiders spin their silk from an aqueous solution to a solid fiber in ambient conditions. However, to date, the assembly mechanism in the spider silk gland has not been satisfactorily explained. In this paper, we use molecular dynamics simulations to model Nephila clavipes MaSp1 dragline silk formation under shear flow...

journal_title：Biomacromolecules

authors： Giesa T,Perry CC,Buehler MJ

更新日期：2016-02-08 00:00:00