Abstract：
:The activities of vanadium oxide (V2O3), vanadyl sulfate (VOSO4) and ammonium metavanadate (NH4VO3) in inducing sister chromatid exchange (SCE) and chromosomal aberrations (CAb) were assayed in Chinese hamster ovary cells. The toxic concentrations (TC50) for these compounds were found to be 25, 23 and 16 micrograms elemental vanadium/ml, respectively. At does 1/50-1/4 TC50, vanadium compounds were able to induce significant increases (P less than 0.01) in the SCE frequency with or without the addition of rat hepatic S9 mix. These compounds also induced CAb in the cells at doses closely equivalent to the TC50.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Owusu-Yaw J,Cohen MD,Fernando SY,Wei CIdoi
10.1016/0378-4274(90)90026-isubject
Has Abstractpub_date
1990-02-01 00:00:00pages
327-36issue
2-3eissn
0378-4274issn
1879-3169pii
0378-4274(90)90026-Ijournal_volume
50pub_type
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journal_title：Toxicology letters
pub_type： 杂志文章
doi：10.1016/j.toxlet.2013.01.004
更新日期：2013-04-12 00:00:00
