Pericardial effusion and atrial thrombosis: a rare complication of childhood leukemia.

Abstract:

BACKGROUND:Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia. CASE PRESENTATION:We report a 15-year-old girl with T-cell ALL, who presented initially with pericardial effusion and cardiac tamponade and subsequently developed right atrial mass. The mediastinal and right atrial masses were excised by surgical procedure as a treatment strategy for prevention of arrhythmia and sudden death. CONCLUSION:T-cell ALL can present with pericardial and mediastinal involvement as an initial manifestation. Pericardiocenthesis and systemic anticancer chemotherapy without local chemotherapy should be considered in these cases.

journal_name

Iran J Pediatr

authors

Zareifar S,Cheriki S,Namdari M,Farahmandfar M,Jannati A

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

117-20

issue

1

eissn

2008-2142

issn

2008-2150

journal_volume

22

pub_type

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