Abstract:
OBJECTIVE:Beta thalassemia major is a prevalent hereditary disease in Mediterranean region especially Iran. Early blood transfusion is necessary for most of the patients and frequent transfusion can cause various medical problems for the patients. The aim of this study was to find major causes of hospital admission in beta thalassemia major patients to reach the accurate preventive and therapeutic plans for these patients. METHODS:Four hundred twenty six patients were admitted to the Nemazee Hospital (the main University referral Hospital Center affiliated to Shiraz University of Medical Sciences in Fars Province, southern Iran) during 3 years period (January 2007 to January 2010). A questionnaire was filled containing age, gender, hemoglobin level, frequency of blood transfusions, deferoxamine injection, cause of hospital admission and hospital course. FINDINGS:The mean age of patients was 11.28 years. The mean serum ferritin level was 1820±749 µg/lit. Two hundred fifty five (59.75%) patients were male and 171 (40.25%) patients were female. The top five most prevalent causes of hospital admission were splenectomy (21.8%), infections (19.9%), congestive heart failure (19.0%), diabetes mellitus (13.4%), and Liver biopsy (11.5%). (P=0.0002) CONCLUSION:Results of this study revealed that infections and complications due to iron overload are major causes of hospital admission in beta thalassemia major patients.
journal_name
Iran J Pediatrjournal_title
Iranian journal of pediatricsauthors
Karimi M,Emadmarvasti V,Hoseini J,Shoja Lsubject
Has Abstractpub_date
2011-12-01 00:00:00pages
509-13issue
4eissn
2008-2142issn
2008-2150journal_volume
21pub_type
杂志文章abstract:BACKGROUND:Classic Pelizaeus-Merzbacher disease is a rare x-linked disorder of proteolipid protein expression first described clinically in 1885. This disease is characterized by abnormal eye movements, very slow motor development and involuntary movements. The causative gene is PLP1. CASE PRESENTATION:A 1-year-old bo...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:The surveillance of acute flaccid paralysis (AFP) is a key strategy for monitoring the progress of poliomyelitis eradication and is a sensitive measure for detecting potential cases of poliomyelitis and poliovirus infection. This study was conducted to describe the characteristics of patients reported with AF...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Metals such as copper (Cu), zinc (Zn), iron (Fe) are essential for human beings. Chronic metabolic disturbances may result from an excess or deficiency of these metals. Ca and Mg are also nutrient elements and play an important role in biological systems. Thus, it is very important to check regularly trace el...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia. ...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To determine the risk factors associated with lower respiratory tract infections (LRTI) related hospitalizations in preterm infants receiving palivizumab throughout the high season for respiratory syncytial virus (RSV) infection. METHODS:Premature infants who were commenced on palivizumab prophylaxis during ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Growth charts are widely used to assess children's growth status and can provide a trajectory of growth during early important months of life. Racial differences necessitate using local growth charts. This study aimed to provide standardized growth curves of body mass index (BMI) for children living in northe...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Congenital midline cervical cleft (CMCC) is a rare developmental anomaly of the anterior neck, mostly found in Caucasian females. Most authors consider it within the spectrum of branchial arch developmental abnormalities. There have been about 100 reported cases in the literature. However, there is no agreem...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Intracranial arteriovenous malformation rarely causes pulmonary hypertension and congestive heart failure in the newborn. Its diagnosis is challenging because cardiomegaly may suggest an intra-cardiac structural lesion. CASE PRESENTATION:We present two newborns, one 2-day-old male and the other 11-day-old f...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:Paucity of interlobular bile ducts (PIBD), defined as absence or marked decrease in the number of interlobular bile ducts, is one of the causes of neonatal cholestasis. Treatment includes treating the intractable pruritus caused by persistent cholestasis. PIBD can be part of a familial syndrome of cholestasis...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To identify and compare risk factors for recurrent respiratory infections in preschool children between resident and floating population in Yiwu, China. METHODS:Investigations was conducted in resident and floating population in Yiwu city, Zhejiang province. A structured questionnaire was used to collect inf...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Healthcare-associated bloodstream infections (HCA-BSI) are a major cause of morbidity and mortality in neonatal intensive care units (NICUs). OBJECTIVES:We aimed to determine the causative organisms and risk factors of HCA-BSIs in NICUs. METHODS:This study was performed between January 2011 and December 20...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.5213
更新日期:2016-07-27 00:00:00
abstract:BACKGROUND:Hepatitis A virus (HAV) infection constitutes an important health problem in developing countries. It is usually a benign self-limiting disease, but may present with atypical clinical findings. CASE PRESENTATION:A twelve-year-old male with ascites, pleural effusion, and acalculous cholecystitis during the c...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Nijmegen Breakage Syndrome(NBS) is a rare autosomal recessive disorder with specific clinical features, characteristic chromosomal breakage and combined imunodeficiency. Patients with this condition also associate growth retardation with microcephaly, predisposition to malignancy and specific skin manifestat...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Infantile Onset Pompe Disease (IOPD) is a rare autosomal recessive neuromuscular disorder. It is associated with cardiomegaly, hypotonia, paresis, and death in the first year of life. Since 2006, following the use of Alglucosidase alfa as Enzyme Replacement Therapy (ERT), the patients' survival is improved t...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.4473
更新日期:2016-02-01 00:00:00
abstract::Congenital adrenal hyperplasia (CAH) is characterized by impaired biosynthesis of cortisol. 21-hydroxylase deficiency is the most common cause of CAH affecting 1 in 10000-15000 live births over the world. The frequency of the disorder is very high in Iran due to frequent consanguineous marriages. Although biochemical ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Although there are several echocardiographic criteria, there is not yet a general consensus about the diagnosis of left ventricular noncompaction. The current criteria are mostly based on the areas with maximal noncompaction in the heart. The echocardiographer may miss this maximal point leading to a misdiagn...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:Most neonatal encephalopathic disorders appear to be caused by perinatal events. Persistent myocardial ischemia leads to cellular necrosis and release of troponin from cardiac muscles. Fetal distress during labor may be detected by monitoring the fetal heart rate. However little is known about the relationshi...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVES:Henoch-Schonlein Purpura (HSP) is the most widespread systemic vasculitis during childhood. Gastrointestinal tract retention and gastrointestinal bleeding are among its major complications. Neutrophil-Lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are indicators related to inflammatory diseases. ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.8191
更新日期:2016-10-10 00:00:00
abstract::GENETIC DISORDERS ARE TRADITIONALLY CATEGORIZED INTO THREE MAIN GROUPS: single-gene, chromosomal, and multifactorial disorders. Single gene or Mendelian disorders result from errors in DNA sequence of a gene and include autosomal dominant (AD), autosomal recessive (AR), X-linked recessive (XR), X-linked dominant and Y...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Diphallus is a rare anomaly and accompanying anomalies vary from bifid scrotum, bladder exstrophy, imperforate anus and colo-rectal anomaly such as duplication, and other associated anomalies. CASE PRESENTATION:A 2-day old infant is reported with imperforate anus and complete duplication of recto-sigmoid co...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:Due to recent scientific progress in assisted reproductive techniques (ART), infertile couples can now become fertile. Thus, a number of infants in our country are the results of these costly interventions. This study has been undertaken to evaluate the physical growth process of different methods of ART infa...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Burning fat and carbohydrates to provide energy in biological systems causes the formation of free oxygen species. OBJECTIVES:This study aimed to evaluate the oxidative status of serum and breast milk of mothers giving birth prematurely and at full-term. MATERIALS AND METHODS:The study comprised 50 mothers...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.2363
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The most common reason of respiratory distress in the newborn is transient tachypnea of the newborn (TTN). There are some reports saying that TTN is associated with increased frequencies of wheezing attacks. OBJECTIVES:The aims of this study were to determine the risk factors associated with TTN and to dete...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.2295
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate clinical characteristics of ureteroceles particularly for diagnostic and treatment challenges. METHODS:Data about patients treated for ureterocele in the two hospital clinics during 1996- 2009 are retrospectively evaluated. FINDINGS:There were 12 girls and 7 boys. Sympto...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:Neonatal mortality is a major health problem in sub-Saharan Africa and the risk factors are not well established. The objective of this study was to determine the risk factors for neonatal mortality at the Yaounde Gynaeco-Obstetric and Pediatric Hospital. METHODS:We conducted a retrospective and analytic cas...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION:Truncus arteriosus with intact ventricular septum is a rare and unique variant of persistent truncus arteriosus (PTA) which usually presents with central cyanosis and congestive heart failure in neonate and early infancy. Associated cardiac and non-cardiac anomalies may affect morbidity and mortality of th...
journal_title:Iranian journal of pediatrics
pub_type:
doi:10.5812/ijp.2081
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was the evaluation of patients treated with a diagnosis of gastroschisis and to establish the factors which affected the morbidity and mortality. METHODS:Twenty-nine patients, managed for gastroschisis during 2000-2010 were reviewed retrospectively. Patients were analysed in respect to g...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:Cyanotic congenital heart diseases (CCHDs) are a series of cardiac anomalies that have long been recognized as a potential cause of nephropathy. There have been few reports on renal impairment in patients with CCHD before and after corrective cardiac surgery. The aim of this study was to evaluate the prevalen...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:B-type natriuretic peptide (BNP) levels are elevated in children with congenital heart disease involving a left-to-right shunt (LRS) and are also raised in dilated cardiomyopathy (DCM). As far as we know, there are few reports in the literature comparing the change of the NT-proBNP in LRS and DCM especially ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.4485
更新日期:2016-05-15 00:00:00
abstract:BACKGROUND:Allgrove syndrome is a rare autosomal recessive condition characterized by adrenal insufficiency, achalasia, alacrima and occasionally autonomic disturbances. Mutations in the AAAS gene, on chromosome 12q13 have been implicated as a cause of this disorder. CASE(S) PRESENTATION:We present various manifestati...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2010-03-01 00:00:00