Abstract:
OBJECTIVE:The aim of this study was to evaluate the bilirubin albumin (B/A) ratio in comparison with total serum bilirubin (TSB) for predicting acute bilirubin-induced neurologic dysfunction (BIND). METHODS:Fifty two term and near term neonates requiring phototherapy and exchange transfusion for severe hyperbilirubinemia in Children's Medical Center, Tehran, Iran, during September 2007 to September 2008, were evaluated. Serum albumin and bilirubin were measured at admission. All neonates were evaluated for acute BIND based on clinical findings. FINDINGS:Acute BIND developed in 5 (3.8%) neonates. B/A ratio in patients with BIND was significantly higher than in patients without BIND (P<0.001). Receiver operation characteristics (ROC) analysis identified a TSB cut off value of 25 mg/dL [area under the curve (AUC) 0.945] with a sensitivity of 100% and specificity of 85%. Also, according to the ROC curve, B/A ratio cut off value for predicting acute BIND was 8 (bil mg/al g) (AUC 0.957) with sensitivity of 100% and specificity of 94%. CONCLUSION:Based on our results, we suggest using B/A ratio in conjunction with TSB. This can improve the specificity and prevent unnecessary invasive therapy such as exchange transfusion in icteric neonates.
journal_name
Iran J Pediatrjournal_title
Iranian journal of pediatricsauthors
Ardakani SB,Dana VG,Ziaee V,Ashtiani MT,Djavid GE,Alijani Msubject
Has Abstractpub_date
2011-03-01 00:00:00pages
28-32issue
1eissn
2008-2142issn
2008-2150journal_volume
21pub_type
杂志文章abstract:BACKGROUND:Acute lymphoblastic leukemia (ALL) is the most common malignancy diagnosed in children. Extramedullary leukemia including hepatosplenomegaly, lymphadenopathy, and mediastinal mass are the clinical presentations of T-cell ALL. Pericardial effusion and atrial mass are rare presentations of pediatric leukemia. ...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:Cyanotic congenital heart diseases (CCHDs) are a series of cardiac anomalies that have long been recognized as a potential cause of nephropathy. There have been few reports on renal impairment in patients with CCHD before and after corrective cardiac surgery. The aim of this study was to evaluate the prevalen...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Classic Pelizaeus-Merzbacher disease is a rare x-linked disorder of proteolipid protein expression first described clinically in 1885. This disease is characterized by abnormal eye movements, very slow motor development and involuntary movements. The causative gene is PLP1. CASE PRESENTATION:A 1-year-old bo...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:Shiga toxin-producing E. coli (STEC) is a pathogenic E. coli that may cause hemolytic uremic syndrome (HUS) after diarrheal disease through Shiga toxins. Management of the patients with STEC infection is different from that of other diarrheal diseases due to increase in frequency of HUS after antibiotic admin...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:This study aims at providing local reference values for blood pressure by height and determining distribution pattern of systolic and diastolic blood pressure in 6.5-11.5 elementary school children for the first time in Shiraz (Southern Iran). METHODS:Height, systolic blood pressure (SBP) and diastolic blood...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate clinical characteristics of ureteroceles particularly for diagnostic and treatment challenges. METHODS:Data about patients treated for ureterocele in the two hospital clinics during 1996- 2009 are retrospectively evaluated. FINDINGS:There were 12 girls and 7 boys. Sympto...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To analyze the clinical and radiological features of paragonimiasis in children and raise the awareness of this disease. METHODS:A total of 58 paragonimiasis patients were reviewed. They were 42 boys and 16 girls aged 2.0 to 15.3 years. FINDINGS:Among these patients, 20 were diagnosed in the recent 5 years,...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:Epilepsy is a most common serious neurological disorder and is one of the world's most prevalent non-communicable diseases. The aim of this study was to determine the prevalence and risk factors of epilepsy in 0-17 year old children in Trabzon, Turkey. METHODS:A cross-sectional epidemiological investigation ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:Injection of botulinum toxin into the anal sphincter is a novel and safe new treatment of chronic idiopathic constipation and anal fissure in children. The purpose of this study was to determine the utility of intra sphincteric injection of botox in the treatment of children with refractory constipation. MET...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:The objective of this randomized controlled trial was to compare the treatment failure of suspected early onset neonatal sepsis with either 3-day or 5-day course of empirical antibiotic therapy. METHODS:Infants with birth weight over 1500 g and/or gestational age over 34 weeks within 7 days postnatal age wit...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To investigate T-cell immunoglobulin domain and mucin domain-containing molecule-3 (Tim-3) and its ligand galectin-9 mRNA expression in peripheral blood mononuclear cells (PBMCs) from Henoch-Schoenlein Purpura (HSP) patients. METHODS:Quantitative real-time reverse transcription-polymerase chain reaction (PCR...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Burning fat and carbohydrates to provide energy in biological systems causes the formation of free oxygen species. OBJECTIVES:This study aimed to evaluate the oxidative status of serum and breast milk of mothers giving birth prematurely and at full-term. MATERIALS AND METHODS:The study comprised 50 mothers...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.2363
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Human pandemic influenza H(1)N(1) virus as the cause of febrile respiratory infection ranging from self-limited to severe illness has spread globally during 2009. Signs and symptoms of upper and lower respiratory tract involvement, fever, sore throat, rhinitis, myalgia, malaise, headache, chills and fatigue a...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Intracranial arteriovenous malformation rarely causes pulmonary hypertension and congestive heart failure in the newborn. Its diagnosis is challenging because cardiomegaly may suggest an intra-cardiac structural lesion. CASE PRESENTATION:We present two newborns, one 2-day-old male and the other 11-day-old f...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Congenital midline cervical cleft (CMCC) is a rare developmental anomaly of the anterior neck, mostly found in Caucasian females. Most authors consider it within the spectrum of branchial arch developmental abnormalities. There have been about 100 reported cases in the literature. However, there is no agreem...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Atrial septal defect (ASD) is a common congenital heart disease. OBJECTIVES:The aim of this study was to assess the clinical course of ASD, as well as its frequency of spontaneous closure and regression of diameter. METHODS:In a study conducted from 2000 to 2011, 192 consecutive patients with an isolated A...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.4649
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Healthcare-associated bloodstream infections (HCA-BSI) are a major cause of morbidity and mortality in neonatal intensive care units (NICUs). OBJECTIVES:We aimed to determine the causative organisms and risk factors of HCA-BSIs in NICUs. METHODS:This study was performed between January 2011 and December 20...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.5213
更新日期:2016-07-27 00:00:00
abstract:OBJECTIVE:Late-onset sepsis is responsible for high morbidity and mortality in newborn infants in the world and in particular in developing countries. In this study, we evaluated whether clinical characteristics, laboratory parameters and measurements of serum interleukin-8 (IL-8) are able to discriminate between late ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Scrotal exploration is considered the procedure of choice for acute scrotum. OBJECTIVES:We evaluated the importance of early diagnosis and testicular salvage on the therapeutic outcomes of patients with pediatric testicular torsion (TT) and testicular appendage torsion (TAT) in our geographic area. PATIENT...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.248
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the Persian version of the wechsler intelligence scale for children - fourth edition (WISC-IV) and cognitive assessment system (CAS) tests, to determine the correlation between their scales and to evaluate the probable concurrent validity of these tests in patients with le...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:The most common reason of respiratory distress in the newborn is transient tachypnea of the newborn (TTN). There are some reports saying that TTN is associated with increased frequencies of wheezing attacks. OBJECTIVES:The aims of this study were to determine the risk factors associated with TTN and to dete...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.2295
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Infantile Onset Pompe Disease (IOPD) is a rare autosomal recessive neuromuscular disorder. It is associated with cardiomegaly, hypotonia, paresis, and death in the first year of life. Since 2006, following the use of Alglucosidase alfa as Enzyme Replacement Therapy (ERT), the patients' survival is improved t...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:10.5812/ijp.4473
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Neonatal mortality is a major health problem in sub-Saharan Africa and the risk factors are not well established. The objective of this study was to determine the risk factors for neonatal mortality at the Yaounde Gynaeco-Obstetric and Pediatric Hospital. METHODS:We conducted a retrospective and analytic cas...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::Low back pain (LBP) is common among children and adolescents. In younger children particularly those under 3, LBP should be considered as an alarming sign for more serious underlying pathologies. However, similar to adults, non specific low back pain is the most common type of LBP among children and adolescents. In th...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the normative data and psychometric properties of the parent and teacher rating form of the child behavior checklist (CBCL) in an Iranian community sample. METHODS:A sample of 6-12 year old students was randomly selected from ten elementary schools in Tehran, Iran...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:Beta thalassemia major is a prevalent hereditary disease in Mediterranean region especially Iran. Early blood transfusion is necessary for most of the patients and frequent transfusion can cause various medical problems for the patients. The aim of this study was to find major causes of hospital admission in ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:CONTEXT:Neonatal mortality rate is declining globally. The aim of the present study is to identify relevant indicators for assessing newborn care in hospitals by a systematic review. EVIDENCE ACQUISITION:A search on electronic data base and manual searches of personal files for studies on quality indicators of newborn...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.5812/ijp.3706
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was the evaluation of patients treated with a diagnosis of gastroschisis and to establish the factors which affected the morbidity and mortality. METHODS:Twenty-nine patients, managed for gastroschisis during 2000-2010 were reviewed retrospectively. Patients were analysed in respect to g...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Diphallus is a rare anomaly and accompanying anomalies vary from bifid scrotum, bladder exstrophy, imperforate anus and colo-rectal anomaly such as duplication, and other associated anomalies. CASE PRESENTATION:A 2-day old infant is reported with imperforate anus and complete duplication of recto-sigmoid co...
journal_title:Iranian journal of pediatrics
pub_type:
doi:
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:Urinary tract infection (UTI) is one of the most common causes of febrile pediatric diseases. Also, vesicoureteral reflux (VUR) is a significant risk factor for UTI. Voiding cystourethrography (VCUG) is the method of choice for evaluation of VUR. This study was done to predict VUR by DMSA scan (technetium 99 ...
journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00