Abstract:
OBJECTIVE:There are some reports in which a condition of zinc deficiency and its associated outcomes with a change in concentration of serum copper among the thalassemic patients has been highlighted. The aim of this prospective study was to determine the serum zinc and copper levels in children with beta-thalassemia major. METHODS:In this cross sectional study all children under 12 years affected by beta thalassemia major (40 patients) were evaluated for serum zinc and copper levels in Qazvin thalassemia center (Qazvin, Iran) in 2007. Serum measurements for zinc and copper were performed by atomic absorption spectrophotometer. FINDINGS:The mean concentrations of serum zinc and copper levels were 67.35±20.38 and 152.42±24.17 µg/dl respectively. Twenty-six (65%) of thalassemic patients had zinc concentration under 70 µg/dl (hypozincemia). None of the thalassemic children had copper deficiency. No significant correlation between serum zinc level with age, weight, height, body mass index, duration of blood transfusion, desferrioxamine dose and ferritin level was observed in thalassemic patients (P=0.3). CONCLUSION:This study revealed that hypozincemia is common in thalassemic patients, but in contrast, there is no copper deficiency. Further evaluation in this regard is recommended.
journal_name
Iran J Pediatrjournal_title
Iranian journal of pediatricsauthors
Mahyar A,Ayazi P,Pahlevan AA,Mojabi H,Sehhat MR,Javadi Asubject
Has Abstractpub_date
2010-09-01 00:00:00pages
297-302issue
3eissn
2008-2142issn
2008-2150journal_volume
20pub_type
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journal_title:Iranian journal of pediatrics
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journal_title:Iranian journal of pediatrics
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journal_title:Iranian journal of pediatrics
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journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
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journal_title:Iranian journal of pediatrics
pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:
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