Abstract:
:Porcine endogenous retroviruses (PERV) are widely distributed in the genomes of pigs. PERV-A and PERV-B are present in all pigs. They infect human cells in vitro and therefore represent a risk for xenotransplantation when pig cells, tissues or organs are used. PERV-C infects only pig cells and is not present in the genomes of all pigs. However, PERV-A/C recombinants infecting human cells and characterized by high replication titers were found in pigs. To select PERV-C-free animals that cannot generate such recombinants, PCR-based assays were developed (Kaulitz et al., J Virol Methods, 175:60, 2011). When screening for PERV-C in German wild boars (Sus scrofa scrofa), applying these methods, a new variant of PERV-C was identified. Whereas in all 125 wild boar only the new variant of PERV-C was found, different variants were present in some landrace pigs, and most importantly, some pigs were totally free of PERV-C.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Kaulitz D,Mihica D,Adlhoch C,Semaan M,Denner Jdoi
10.1007/s00705-012-1490-9subject
Has Abstractpub_date
2013-02-01 00:00:00pages
341-8issue
2eissn
0304-8608issn
1432-8798journal_volume
158pub_type
杂志文章abstract::Changes in the NP gene of H5N1 highly pathogenic avian influenza (HPAI) viruses have previously been shown to affect viral replication, alter host gene expression levels and affect mean death times in infected chickens. Five amino acids at positions 22, 184, 400, 406, and 423 were different between the two recombinant...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0399-4
更新日期:2009-01-01 00:00:00
abstract::Avian influenza viruses of H3N8, H11N4, H7N7, H8N4, and H5N3 infected mink by contact. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309274
更新日期:1983-01-01 00:00:00
abstract::Cell cultures inoculated with caprine respiratory syncytial virus (RSV) were studied with light, fluorescent, and electron microscopy to determine the morphogenesis and structure of the virus. Small syncytia were seen after 36 hours in culture. After 48 hours in culture, syncytia were large and numerous and pleomorphi...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314543
更新日期:1980-01-01 00:00:00
abstract::In order to investigate the genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) strains currently circulating in the Republic of Ireland (ROI), the ORF5 gene from 17 field strains originating from four vaccinating commercial herds was sequenced and phylogenetically analysed. High genetic v...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04710-7
更新日期:2020-09-01 00:00:00
abstract::The nonstructural rotavirus protein NSP1 binds specifically to viral mRNAs and to interferon regulatory factor 3 (IRF3), inducing IRF3 degradation through a proteasome-dependent pathway. By using a vaccinia virus expression system in mammalian cells, we found that the yield of NSP1 was 8- and 13-fold lower than the vi...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0850-8
更新日期:2007-02-01 00:00:00
abstract::To understand the mode of persistent infection of Seoul virus in rodents, we examined the distribution of the virus genome and antibody production in infected rats. When 1-day-old rats were inoculated with the KI-83-262 strain, the S segment of viral genome was detected in sera, clots, lungs and kidneys from 3 to 184 ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718634
更新日期:1996-01-01 00:00:00
abstract::An assay to characterize plasma human immunodeficiency virus 1 (HIV-1) sequences for patients with low viral loads was developed by combining the selective binding of anti-CD44 MicroBeads with a nested RT-PCR targeting the env C2V4 region. Sequences were obtained from 10 of 20 HIV+ patients who had viral loads below 4...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0659-3
更新日期:2010-06-01 00:00:00
abstract::A novel potyvirus was discovered in Angelica lucida L. (wild celery) and A. genuflexa Nutt. (kneeling Angelica) (family Apiaceae) in the Matanuska- Susitna Valley, Alaska. The experimental plant host range of the virus included species in three families: Chenopodiaceae (Chenopodium amaranticolor Coste et Reyn and Chen...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-1003-4
更新日期:2007-01-01 00:00:00
abstract::A total of 289 cloacal swabs from pigeons from 29 different breeders in Germany were collected. In addition, samples from pigeons exhibited at shows were collected. The detailed health status of the pigeon flocks was recorded. Samples were analysed for the presence of the recently discovered pigeon rotavirus and pigeo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04834-w
更新日期:2021-01-01 00:00:00
abstract::For selecting the neutralizing monoclonal antibodies (N-MAbs) directed to VP4 of rotavirus strain K8, which has unique VP4 neutralization epitopes, we prepared several reassortant viruses by mixed infection of two different strains K8 (serotype 1) and P (serotype 3) in vitro: three reassortant clones having VP4 of K8 ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316751
更新日期:1991-01-01 00:00:00
abstract::Modern adjuvants should induce strong and balanced immune responses, and it is often desirable to induce specific types of immunity. As an example, efficient Th1-immunity-inducing adjuvants are highly in demand. Such adjuvants promote good cell-mediated immunity against subunit vaccines that have low immunogenicity th...
journal_title:Archives of virology
pub_type: 杂志文章,评审
doi:10.1007/s00705-010-0863-1
更新日期:2011-02-01 00:00:00
abstract::DNA of TT virus (TTV), a novel human circovirus, was tested for in 116 mother-infant pairs who had participated in the adult T-cell leukemia prevention program (APP) in Nagasaki, Japan, and refrained from breast-feeding. By polymerase chain reaction with Okamoto's seminested primers, 36 of the 115 (31%) mothers were p...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050044
更新日期:2000-01-01 00:00:00
abstract::Two and a half hours after infection with a high dose of different strains of HSV-1 which induce rounding of cells, breakdown of actin containing microfilaments can be observed. At the periphery of the cell, actin containing knob-like protuberances were visible. Later on, actin seems to be located exclusively on the s...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314285
更新日期:1986-01-01 00:00:00
abstract::Twenty-eight Belgian field isolates of bovine herpesvirus 4 (BHV-4) coming from a variety of clinical diseases have been studied by restriction analysis and Southern blot hybridization. The unique central part of the genome was very well conserved among strains; only one variation in a restriction site was detected in...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01319227
更新日期:1991-01-01 00:00:00
abstract::The effects of human alpha-, beta-, or gamma-interferon (IFN) on the replication and production of human T-lymphotrophic virus type-I (HTLV-I) were investigated in a human T-cell line, MT-2. Virus transmission and production estimated by syncytium formation and HTLV-I-associated reverse transcriptase (RT) activity wer...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310623
更新日期:1990-01-01 00:00:00
abstract::The 3'-terminal nucleotides of the genome segments of influenza C/Taylor/47. C/Bavaria/79 and C/Johannesburg/1/66 were identified by two RNA sequencing techniques. These comprised 11 nucleotides (3' UCGUCUUCGUC) which were found to be conserved among the genome segments of each virus. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310664
更新日期:1984-01-01 00:00:00
abstract::Mouse embryo fibroblasts and mouse adrenal tumor cells support the replication of encephalomyocarditis (EMC) virus, whereas rat glial and rat hepatoma cells are non-permissive. These differences in susceptibility were not due to the lack of virus attachment to rat cells. The findings that rat cells could be transfecte...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310884
更新日期:1986-01-01 00:00:00
abstract::Transgenic plants represent an inexpensive alternative to classical fermentation systems for production of recombinant subunit vaccines. Transgenic potato plants were created that express the N-terminal domain of the glycoprotein S (N-gS) from Transmissible gastroenteritis coronavirus (TGEV), containing the major anti...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050070087
更新日期:2000-01-01 00:00:00
abstract::The viral DNAs induced by the unclassified animal virus, chicken anaemia agent (CAA), during replication in MDCC-MSB 1 cells have been investigated. Analyses after S1 nuclease, restriction endonuclease and denaturation treatments indicated that infected cell extracts contained genome-size, single-stranded DNA (M(r) 2....
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309811
更新日期:1992-01-01 00:00:00
abstract::The stability of regions containing tandemly reiterated sequences in the S component of the herpes simplex virus type 1 (HSV-1) genome was determined, by comparing restriction fragments of the regions among sets of HSV-1 isolates derived from a single source. The 6 reiterations examined were grouped into three. Reiter...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313958
更新日期:1989-01-01 00:00:00
abstract::Cell-mediated immune response was studied in experimental herpetic infection in mice. Our data suggest that herpes simplex virus induced immunosuppression in mice. This depression was documented by the unresponsiveness of the lymphocytes to PHA stimulation in vitro and by the enhanced susceptibility of adult mice to C...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF02175597
更新日期:1975-01-01 00:00:00
abstract::A wheat-infecting furovirus found in Tompkins County, New York, U.S.A. was identified as a strain of Soil-borne wheat mosaic virus (SBWMV) by means of sequence analyses of portions of its RNA 1 and 2. The nucleotide sequences of several of its genes differed by c. 9 to 12% from those of the corresponding genome region...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050200011
更新日期:2002-03-01 00:00:00
abstract::Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for th...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1731-6
更新日期:2014-03-01 00:00:00
abstract::The effect of temperature on the response of tomato (Lycopersicon esculentum Mill. cv. Rutgers) to infections with the necrogenic cucumber mosaic virus (CMV) satellite D-CARNA 5 was investigated with each of four CMV strains D, 1, Y and S functioning as helper virus. At 24 degrees C lethal necrosis was observed in all...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309724
更新日期:1995-01-01 00:00:00
abstract::The revised International Code of Virus Classification and Nomenclature [7] followed by the Seventh Report of the International Committee on Taxonomy of Viruses (ICTV) [9] have generated a lot of criticism [2,4-6]. The main causes of criticism are (i) use of monomials instead of non-latinized binomials, as has been pr...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050200051
更新日期:2002-11-01 00:00:00
abstract::Type I interferon (IFN) exerts strong antiviral activity, particularly against human immunodeficiency virus (HIV), and although several viral proteins have been shown to deregulate IFN induction, little is known about the induction of type I IFNs by HIV RNAs. In the present study, we used the stable isotope labeling w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2372-8
更新日期:2015-05-01 00:00:00
abstract::A large sheep flock screened over a two-year period showed active spreading of Schmallenberg virus (SBV) during the summers of 2011 and 2012. Transplacental infections were observed during the two associated lambing periods (the winters of 2012 and 2013). Analysis of small (S) segment sequences of 38 SBV-positive samp...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2787-x
更新日期:2016-05-01 00:00:00
abstract::To date, most members of the Siphoviridae family of bacteriophages remain unclassified, including the 46 staphylococcal phages for which the complete genome sequences have been deposited in public databases. Comparative nucleotide and protein sequence analysis, in addition to available data on phage morphology, allowe...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1833-1
更新日期:2014-02-01 00:00:00
abstract::We detected a novel bovine hepacivirus N (HNV) subtype, IME_BovHep_01, in the serum of cattle in Tengchong, Yunnan, China, by high-throughput sequencing. The complete genome of IME_BovHep_01, was sequenced using an Illumina MiSeq sequencer and found to be 8850 nt in length, encoding one hypothetical protein. BLASTn an...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04611-9
更新日期:2020-06-01 00:00:00
abstract::The amount of viroid RNA required for sequence analysis can be reduced by five to six orders of magnitude when a modified "polymerase chain reaction" (PCR) is used for the amplification of the reversely transcribed, overlapping viroid cDNAs. By applying this procedure it is possible to establish the molecular structur...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313962
更新日期:1989-01-01 00:00:00