The PNarec method for detection of ancient recombinations through phylogenetic network analysis.

Abstract:

:Recombinations are known to disrupt bifurcating tree structure of gene genealogies. Although recently occurred recombinations are easily detectable by using conventional methods, recombinations may have occurred at any time. We devised a new method for detecting ancient recombinations through phylogenetic network analysis, and detected five ancient recombinations in gibbon ABO blood group genes [Kitano et al., 2009. Mol. Phylogenet. Evol., 51, 465-471]. We present applications of this method, now named as "PNarec", to various virus sequences as well as HLA genes.

journal_name

Mol Phylogenet Evol

authors

Saitou N,Kitano T

doi

10.1016/j.ympev.2012.09.015

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

507-14

issue

2

eissn

1055-7903

issn

1095-9513

pii

S1055-7903(12)00372-7

journal_volume

66

pub_type

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