当前位置： SCI文献检索 > ATHEROSCLEROSIS期刊下所有文献 > Endogenous sex hormones impact the progression of subclinical atherosclerosis in women during the menopausal transition.

Endogenous sex hormones impact the progression of subclinical atherosclerosis in women during the menopausal transition.

Abstract：

OBJECTIVE:To determine whether endogenous sex hormones (estradiol (E2), testosterone (T), sex hormone binding globulin (SHBG), and follicle stimulating hormone (FSH)) are longitudinally associated with progression of atherosclerosis among women at midlife. METHODS:249 Pre- or early peri-menopausal women (42-57 years) from the Study of Women's Health Across the Nation (SWAN) were followed for up to 9 years (median = 3.7 years) and had up to 5 repeated measures of common carotid intima-media thickness (IMT) and adventitial diameter (AD). Linear mixed models were used for statistical analysis. Final models included age at baseline, time since baseline, cycle day of blood draw, race, income, SBP, BMI, insulin resistance index, lipids, C-reactive protein and co-morbidity. RESULTS:In final models for IMT, each one log unit decrease in SHBG was associated with a 0.005 mm/year increase in IMT progression (P = 0.003). E2, T, and FSH were not associated with level or progression of IMT. For AD, each one log unit decrease in E2 was associated with a 0.012 mm/year increase in AD progression (P = 0.04) and each one log unit increase in FSH was associated with a 0.016 mm/year increase in AD progression (P = 0.003). T and SHBG were not associated with progression or level of AD. CONCLUSIONS:Independent of SBP, BMI, lipids and other covariates, lower E2 and SHBG, and higher FSH were associated with increased subclinical atherosclerosis progression in women at midlife.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

El Khoudary SR,Wildman RP,Matthews K,Thurston RC,Bromberger JT,Sutton-Tyrrell K

doi

10.1016/j.atherosclerosis.2012.07.025

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

180-6

issue

1

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(12)00497-2

journal_volume

225

pub_type

杂志文章

相关文献

ATHEROSCLEROSIS文献大全
  • The effect of population density on the development of experimental atherosclerosis in female mice.

    abstract：:The effect of cage population density on plasma lipids and the development of atherosclerosis was examined in female C57BL/6 mice. Mice were housed at a density of one, two or five animals per cage and fed an atherogenic diet for 28 weeks. Subsequently, the animals were bled, sacrificed, the hearts removed and the ext...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(94)05502-a

    authors： Lin AH,Castle CK,Melchior GW,Marotti KR

    更新日期：1995-05-01 00:00:00

  • Sugar sweetened beverages consumption and risk of coronary heart disease: a meta-analysis of prospective studies.

    abstract：OBJECTIVE:To summarize the evidence with respect to sugar sweetened beverages (SSBs) consumption and risk of coronary heart disease (CHD) and to recommend field standards for future analysis on this topic. METHODS:We searched for articles published up to February 2013 through PubMed, EMbase, and Cochrane Library Datab...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.atherosclerosis.2014.01.037

    authors： Huang C,Huang J,Tian Y,Yang X,Gu D

    更新日期：2014-05-01 00:00:00

  • Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells.

    abstract：OBJECTIVE:Endothelial lipase (EL) is a new member of triacylglycerol lipase family that has been shown to decrease high-density lipoprotein (HDL) cholesterol levels leading to increased risk of atherosclerosis. Its expression is increased during inflammation and by inflammatory cytokines. Sulforaphane (SFN) is a natura...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.07.015

    authors： Kivelä AM,Mäkinen PI,Jyrkkänen HK,Mella-Aho E,Xia Y,Kansanen E,Leinonen H,Verma IM,Ylä-Herttuala S,Levonen AL

    更新日期：2010-11-01 00:00:00

  • Efficacy and safety of ciprofibrate in hyperlipoproteinaemias.

    abstract：:Ciprofibrate is an effective treatment for three main types of atherogenic hyperlipoproteinaemia: type IIa hypercholesterolaemia, type IIb combined hyperlipidaemia, and type IV hypertriglyceridaemia. In type IIa hypercholesterolaemia, administration of 100 mg/day of ciprofibrate, to approximately 3000 patients, decrea...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/0021-9150(96)05861-3

    authors： Turpin G,Bruckert E

    更新日期：1996-07-01 00:00:00

  • Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia.

    abstract：BACKGROUND AND AIMS:Although familial hypercholesterolemia (FH) can be effectively managed using cholesterol-lowering medication, patients often fall short of complete treatment adherence. Identifying the psychological factors associated with self-regulation of FH medication is important to inform interventions to maxi...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.atherosclerosis.2018.06.010

    authors： Hagger MS,Hardcastle SJ,Hu M,Kwok S,Lin J,Nawawi HM,Pang J,Santos RD,Soran H,Su TC,Tomlinson B,Watts GF

    更新日期：2018-10-01 00:00:00

  • The clinical importance of serum γ-glutamyltransferase level as an early predictor of obesity development in Korean men.

    abstract：BACKGROUND AND OBJECTIVE:Serum γ-glutamyl transferase (GGT) levels are known to be positively associated with obesity. We aimed at verifying an association between baseline GGT levels and the development of obesity in Korean men. PATIENTS AND METHODS:This prospective cohort study was performed on 18,510 initially non-...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.01.029

    authors： Suh YJ,Park SK,Choi JM,Ryoo JH

    更新日期：2013-04-01 00:00:00

  • Crocus sativus L. aqueous extract reduces atherogenesis, increases atherosclerotic plaque stability and improves glucose control in diabetic atherosclerotic animals.

    abstract：BACKGROUND AND AIMS:We aimed to evaluate a possible atheroprotective effect of saffron aqueous extract (SFE), and its potential anti-inflammatory mechanisms, in apoE knockout (ApoE-/-) mice. METHODS:Fifty male, ApoE-/- mice, fed a high-fat diet (HFD) for 12 weeks, were randomized into 5 groups: (1) baseline group, eut...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.10.032

    authors： Christodoulou E,Kadoglou NPE,Stasinopoulou M,Konstandi OA,Kenoutis C,Kakazanis ZI,Rizakou A,Kostomitsopoulos N,Valsami G

    更新日期：2018-01-01 00:00:00

  • Ultrasonography of achilles tendons in primary hypercholesterolemia. Comparison with computed tomography.

    abstract：:Tendon xanthoma are a hallmark of familial hypercholesterolemia and are among its earliest clinical manifestations. Achilles tendon size, advanced to a generally accepted marker, is virtually specific for the disease and easily accessible for measurement. Hypercholesterolemic patients with coronary heart disease have ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(88)90242-0

    authors： Steinmetz A,Schmitt W,Schuler P,Kleinsorge F,Schneider J,Kaffarnik H

    更新日期：1988-12-01 00:00:00

  • Arterial endothelial function and wall thickness in familial hypercholesterolemia and familial combined hyperlipidemia and the effect of statins. A systematic review and meta-analysis.

    abstract：BACKGROUND:To evaluate the impact of familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH) on arterial properties and the effects of statins. METHODS:We meta-analyzed 51 studies providing data for 4,057 FH patients and 732 FCH patients with random-effects models, meta-regression analysis and pu...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.atherosclerosis.2010.10.008

    authors： Masoura C,Pitsavos C,Aznaouridis K,Skoumas I,Vlachopoulos C,Stefanadis C

    更新日期：2011-01-01 00:00:00

  • A novel antioxidant 3,7-dihydroxy-isoflav-3-ene (DHIF) inhibits neointimal hyperplasia after vessel injury attenuating reactive oxygen species and nuclear factor-kappaB signaling.

    abstract：:Reactive oxygen species (ROS) contribute to neointimal smooth muscle proliferation by yet to be defined mechanisms. We examined the effects of a novel isoflavone 3,7-dihydroxy-isoflav-3-ene (DHIF) on development of neointimal lesions in relation to ROS elevations and cell signaling in injured arteries. Carotid arterie...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.09.005

    authors： Kanellakis P,Pomilio G,Walker C,Husband A,Huang JL,Nestel P,Agrotis A,Bobik A

    更新日期：2009-05-01 00:00:00

  • Plasma MR-proANP levels are associated with carotid intima-media thickness in the general community: the KORA F4 study.

    abstract：OBJECTIVE:Subjects with metabolic syndrome (MetS) and individuals with type 2 diabetes are at high risk for vascular complications. Hormones acting on vascular endothelium may be involved in the atherogenic process associated with metabolic disorders. The objective of this study was to determine the correlation of pro-...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.07.047

    authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Thiery J,Rathmann W,Seissler J

    更新日期：2013-10-01 00:00:00

  • Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient mice.

    abstract：:Inflammatory cytokines, including tumor necrosis factor-alpha (TNF-alpha) have been implicated in atherogenesis. However, the precise role of TNF-alpha in atherogenesis is still unclear. To examine the effect of TNF-alpha on atherogenesis, we generated compound-deficient mice in apolipoprotein E (apoE) and TNF-alpha (...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2004.11.016

    authors： Ohta H,Wada H,Niwa T,Kirii H,Iwamoto N,Fujii H,Saito K,Sekikawa K,Seishima M

    更新日期：2005-05-01 00:00:00

  • Inhibition of human neutrophil reactive oxygen species production and p67phox translocation by cigarette smoke extract.

    abstract：:The association between cigarette smoking and atherogenesis is well established. Inflammatory cells may participate in atherogenesis via activation of the NADPH oxidase and the subsequent production of reactive oxygen species (ROS), which exacerbates endothelial injury. However, little is known about the ability of ci...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2004.11.011

    authors： Dunn JS,Freed BM,Gustafson DL,Stringer KA

    更新日期：2005-04-01 00:00:00

  • Assessment of coronary plaque characteristics by optical coherence tomography in patients with diabetes mellitus complicated with unstable angina pectoris.

    abstract：BACKGROUND:Diabetic patients are characterised by poorer prognosis and more cardiovascular complications compared with non-diabetic patients, which may be due to metabolic abnormalities and atherosclerotic plaque characteristics. METHODS:Patients with unstable angina pectoris were enrolled in the study and divided int...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.09.019

    authors： Feng T,Yundai C,Lian C,Zhijun S,Changfu L,Jun G,Hongbin L

    更新日期：2010-12-01 00:00:00

  • Cultured bovine aortic endothelial cells show increased histamine metabolism when exposed to oscillatory shear stress.

    abstract：:Oscillatory shear stress applied to the lining of blood vessels causes endothelial cell injury, one of the essential postulated prerequisites to the development of atherosclerosis. The purpose of this investigation was to study effects of shear stress on bovine aortic endothelial cells (BAEC), in vitro, for varying le...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(87)90054-2

    authors： Skarlatos SI,Hollis TM

    更新日期：1987-03-01 00:00:00

  • Prognostic value of coronary artery disease-reporting and data system (CAD-RADS) score for cardiovascular events in ischemic stroke.

    abstract：BACKGROUND AND AIMS:The coronary artery disease-reporting and data system (CAD-RADS) was recently developed to standardize CAD classifications and incorporate clinical management. We aimed to investigate the prognostic value and additional risk stratification benefits of CAD-RADS compared to coronary artery calcium sco...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2019.05.022

    authors： Nam K,Hur J,Han K,Im DJ,Suh YJ,Hong YJ,Lee HJ,Kim YJ,Choi BW

    更新日期：2019-08-01 00:00:00

  • Hematoporphyrin binding to cultured aortic smooth muscle cells from spontaneously atherosclerotic turkey.

    abstract：:Porphyrins are known to be accumulated in vivo by tumors and atherosclerotic plaques. We studied the interaction of cultured aortic smooth muscle cells (SMC) from spontaneously atherosclerotic Broad Breasted White Turkeys (BBWT) with free hematoporphyrin (Hp) and low density lipoprotein (LDL)-Hp complexes. A significa...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(88)90086-x

    authors： Scannapieco G,Pagnan A,Pauletto P,Mattiello A,Biffanti S,Jori G,Dal Palù C

    更新日期：1988-08-01 00:00:00

  • Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia.

    abstract：BACKGROUND:Astaxanthin has been reported to improve dyslipidemia and metabolic syndrome in animals, but such effects in humans are not well known. METHODS:Placebo-controlled astaxanthin administration at doses of 0, 6, 12, 18 mg/day for 12 weeks was randomly allocated to 61 non-obese subjects with fasting serum trigly...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.atherosclerosis.2009.10.012

    authors： Yoshida H,Yanai H,Ito K,Tomono Y,Koikeda T,Tsukahara H,Tada N

    更新日期：2010-04-01 00:00:00

  • A novel cardiovascular death prediction model for Chinese individuals: A prospective cohort study of 381,963 study participants.

    abstract：BACKGROUND AND AIMS:We aimed at developing a novel risk prediction model for death from cardiovascular disease (CVD) for Chinese individuals, based upon a large cohort from Taiwan. METHODS:This Chinese cohort came from Taiwan, with 381,963 individuals free from CVD, recruited from a private health surveillance program...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.07.016

    authors： Hu WS,Lee JH,Tsai MK,Wen CP

    更新日期：2017-09-01 00:00:00

  • Influence of sialic acid content of low-density lipoprotein particles on endothelium-dependent vasorelaxation in rabbit aorta.

    abstract：:Low-density lipoprotein (LDL) concentration in plasma is an important predictor for atherosclerosis, and desialylated LDL has been proposed to be particularly atherogenic. Atherosclerosis is also associated with vascular endothelial dysfunction. We therefore wished to test the hypothesis that removal of sialic acid re...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00479-2

    authors： Stratton PD,Lumb PJ,Paganga G,Crook MA,Ferro A

    更新日期：2001-02-01 00:00:00

  • Expression and regulation of 12/15-lipoxygenases in human primary macrophages.

    abstract：OBJECTIVES:Atherosclerosis is a chronic disease characterized by two main features, lipid retention and inflammation. The 12/15-lipoxygenases play a two-faced role in atherosclerosis with pro-inflammatory effects through oxidation of LDL and anti-inflammatory effects through lipid mediator synthesis. In cells involved ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2012.07.022

    authors： Wuest SJ,Crucet M,Gemperle C,Loretz C,Hersberger M

    更新日期：2012-11-01 00:00:00

  • Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK.

    abstract：:Endothelial cell lipotoxicity mediated by accumulation of free fatty acids is an early event in the pathogenesis of atherosclerosis. The energy-sensor AMP-activated protein kinase (AMPK) is a key regulator of endothelial cell lipid metabolism. To test the hypothesis that bradykinin (BK) regulates AMPK and fatty acid o...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.12.003

    authors： Mount PF,Lane N,Venkatesan S,Steinberg GR,Fraser SA,Kemp BE,Power DA

    更新日期：2008-09-01 00:00:00

  • The dyslipoproteinemias of diabetes.

    abstract：:Atherosclerosis is the most frequent complication of diabetes. There are many potentially atherogenic factors in diabetes that may underlie this problem. Of these, one is the group of dyslipoproteinemias. In diabetes there are both qualitative and quantitative changes in the plasma lipoproteins. Based on pathophysiolo...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/0021-9150(94)05373-q

    authors： Steiner G

    更新日期：1994-10-01 00:00:00

  • The use of polymorphic DNA and protein markers for the third complement component for determining linkage of familial hypercholesterolaemia.

    abstract：:We have used DNA and protein polymorphisms for the third complement component (C3) to assess the potential of DNA markers in the diagnosis and study of familial hypercholesterolaemia (FH), and to confirm the reported linkage between FH and C3. The inheritance of FH and the C3 gene has been studied in 10 families by co...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(84)90056-x

    authors： Humphries SE,Donald JA,McFadden JJ,Shull S,Williamson R,Jowett NI,Galton DJ,Julsrud JO,Berg K,Heiberg A

    更新日期：1984-09-01 00:00:00

  • Low-grade albuminuria is associated with peripheral artery disease in Chinese diabetic patients.

    abstract：BACKGROUND:Increasing studies have suggested that albuminuria might be an important risk factor for peripheral artery disease (PAD). However, studies focusing on the association between low-grade albuminuria and PAD are limited. It would be of great interest to elucidate the association between low-grade albuminuria an...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.11.046

    authors： Xu B,Dai M,Li M,Sun K,Zhang J,Wang T,Sun J,Chen Y,Xu M,Lu J,Bi Y

    更新日期：2014-02-01 00:00:00

  • Association of pericoronary fat volume with atherosclerotic plaque burden in the underlying coronary artery: a segment analysis.

    abstract：OBJECTIVE:We aimed to determine, whether the amount of local pericoronary fat volume is associated with the presence of plaque burden in the underlying coronary artery segment. METHODS:We assessed 311 coronary segments from ECG-gated contrast-enhanced dual-source computed tomography for presence of plaque as well as s...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.02.013

    authors： Mahabadi AA,Reinsch N,Lehmann N,Altenbernd J,Kälsch H,Seibel RM,Erbel R,Möhlenkamp S

    更新日期：2010-07-01 00:00:00

  • Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: a twin study.

    abstract：OBJECTIVE:Atherosclerosis is an inflammatory process resulting from the interaction between genetic and environmental factors. Leukotrienes are inflammatory mediators generated from arachidonic acid, and genetic polymorphisms involved in leukotriene metabolism are implicated in atherosclerosis. The objectives of this s...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2012.10.048

    authors： Zhao J,Goldberg J,Vaccarino V

    更新日期：2013-01-01 00:00:00

  • A sensitive RNase protection assay for the quantitation of the mRNAs for the LDL receptor and HMG-CoA reductase in human total RNA. Effects of treatments on cells in culture designed to up- and down-regulate expression of the LDL receptor.

    abstract：:Regulation of expression of the genes for the low density lipoprotein receptor (LDLR) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) is of central importance in the control of cholesterol metabolism and thus in influencing the concentration of low density lipoprotein in the plasma. This can be studied by i...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(91)90246-y

    authors： Le Cras TD,Gherardi E,Bowyer DE

    更新日期：1991-09-01 00:00:00

  • Inhibition of intimal thickening of the carotid artery of rabbits and of outgrowth of explants of aorta by probucol.

    abstract：:The effect of administration of probucol in preventing intimal thickening of rabbit carotid artery after balloon catheter injury and the mechanism of action of the drug were studied. Groups of 6 male New Zealand-White rabbits were given normal diet (Group I), high cholesterol diet (Group II) or high cholesterol diet p...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(92)90127-3

    authors： Shinomiya M,Shirai K,Saito Y,Yoshida S

    更新日期：1992-12-01 00:00:00

  • Platelet factors and the human vascular wall. Part 2. Such factors are not required for endothelial cell proliferation and migration.

    abstract：:The effects of platelet factors on human umbilical venous endothelial cell DNA-synthesis at various serum concentrations were studied. While [3H]thymidine uptake of these cells was almost linearly related to the concentration of serum in the culture medium, no significant differences were found at any serum level betw...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(78)90168-5

    authors： Thorgeirsson G,Robertson AL Jr

    更新日期：1978-10-01 00:00:00