Abstract:
UNLABELLED:The retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. RESULTS:During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn't lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.
journal_name
Hamostaseologiejournal_title
Hamostaseologieauthors
Kocher S,Asmelash G,Makki V,Müller S,Krekeler S,Alesci S,Miesbach Wsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
S39-42eissn
0720-9355issn
2567-5761pii
12410S39journal_volume
32 Suppl 1pub_type
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