Cloning of arctic lamprey Lethenteron camtschaticum cd9 with roles in the immune response.

Abstract:

:In this study, the cd9 gene, a member of the tetraspanin superfamily and involved in various cellular processes, was cloned from Lethenteron camtschaticum. Both real-time PCR and immunohistochemical assays showed broad distribution of cd9 in various L. camtschaticum tissues. In addition, expression levels of Cd9 mRNA were up-regulated in the liver and heart after stimulation by lipopolysaccharide. Flow cytometric analyses demonstrated that cd9 was detected on the leukocytes and that the expression level was higher on granulocytes than on lymphocytes, which implied that cd9 was mainly involved in innate immunity.

journal_name

J Fish Biol

journal_title

Journal of fish biology

authors

Wu F,Su P,Chen L,Li M,Liu X,Li Q

doi

10.1111/j.1095-8649.2012.03299.x

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

1147-57

issue

4

eissn

0022-1112

issn

1095-8649

journal_volume

81

pub_type

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