Hyperintense HCC on hepatobiliary phase images of gadoxetic acid-enhanced MRI: correlation with clinical and pathological features.

Abstract:

PURPOSE:To retrospectively determine whether the hyperintense hepatocellular carcinomas (HCCs) seen on the hepatobiliary phase of gadoxetic acid-enhanced MR imaging (EOB-MRI) might have different histologic characteristics from usual hypointense HCCs. MATERIALS AND METHODS:Two hundred three surgically proven HCCs from 192 patients who underwent preoperative EOB-MRI were analyzed. The demographic and histologic characteristics of hyperintense HCCs were compared with usual hypointense HCCs by using the t-test or Fisher's exact test. RESULTS:By visual assessment, 18 (8.8%) tumors were classified as hyperintense HCCs. Patients with hyperintense HCC were significantly (p<0.05) older (60.1 vs. 55.2 years) than those with hypointense HCCs. Hyperintense HCCs showed significantly lower rate of microvascular invasion (27.8% vs. 53.5%) and significantly higher rate of peliosis (61.1% vs. 30.8%). Hyperintense HCCs were more frequently expanding type, and none showed infiltrative type or scirrhous histologic pattern. CONCLUSIONS:Hyperintense HCCs seem to have clinical and histologic features that might be related with more favorable outcomes.

journal_name

Eur J Radiol

authors

Kim JY,Kim MJ,Kim KA,Jeong HT,Park YN

doi

10.1016/j.ejrad.2012.07.021

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

3877-82

issue

12

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(12)00390-7

journal_volume

81

pub_type

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