Abstract:
:Twenty publications from twelve prospective cohorts have evaluated associations between flavonoid intakes and incidence or mortality from cardiovascular disease (CVD) among adults in Europe and the United States. The most common outcome was coronary heart disease mortality, and four of eight cohort studies reported significant inverse associations for at least one flavonoid class (multivariate adjusted p(trend) < 0.05). Three of seven cohorts reported that greater flavonoid intake was associated with lower risk of incident stroke. Comparisons among the studies were difficult because of variability in the flavonoid classes included, demographic characteristics of the populations, outcomes assessed, and length of follow-up. The most commonly examined flavonoid classes were flavonols and flavones combined (11 studies). Only one study examined all seven flavonoid classes. The flavonol and flavone classes were most strongly associated with lower coronary heart disease mortality. Evidence for protection from other flavonoid classes and CVD outcomes was more limited. The hypothesis that flavonoid intakes are associated with lower CVD incidence and mortality requires further study.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Peterson JJ,Dwyer JT,Jacques PF,McCullough MLdoi
10.1111/j.1753-4887.2012.00508.xsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
491-508issue
9eissn
0029-6643issn
1753-4887journal_volume
70pub_type
杂志文章,评审abstract::There is much (renewed) interest about the effects of salicylates on food intolerance, attention-deficit disorders, and cardiovascular disease. Current evidence for the efficacy of salicylate-elimination diets in the treatment of attention-deficit disorders and hyperactivity is weak, and further investigation is requi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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更新日期:1993-05-01 00:00:00
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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journal_title:Nutrition reviews
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pub_type: 历史文章,杂志文章
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更新日期:2009-02-01 00:00:00
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journal_title:Nutrition reviews
pub_type: 历史文章,杂志文章
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更新日期:2012-07-01 00:00:00
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