Two new metabolites from a soil fungus Curvularia affinis strain HS-FG-196.

Abstract:

:Two new metabolites, pyrenocine J (1) and pyrenochaetic acid D (2), together with two known metabolites, pyrenocine A (3) and pyrenochaetic acid A (4), were isolated from a soil fungus, Curvularia affinis strain HS-FG-196. Their structures were established by extensive spectroscopic analysis. Compound 1 showed cytotoxic activity against the human hepatic cancer cell line HepG2 with an IC(50) value of 28.5 μg/ml.

journal_name

J Asian Nat Prod Res

authors

Zhang H,Mao LL,Qian PT,Shan WG,Wang JD,Bai H

doi

10.1080/10286020.2012.713351

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

1078-83

issue

11

eissn

1028-6020

issn

1477-2213

journal_volume

14

pub_type

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