Blood pressure variability, cardiovascular risk, and risk for renal disease progression.

abstract：:Salt-sensitive hypertension is closely related with natriuretic capacity of the kidney. Besides several genome-wide research reported candidate gene or gene polymorphism responsible for salt-sensitive hypertension, recently, several new factors for acquired salt-sensitive hypertension are reported. Among them, we have...

journal_title：Current hypertension reports

authors： Shimosawa T,Mu S,Shibata S,Fujita T

更新日期：2012-10-01 00:00:00

abstract：:Obstructive sleep apnea is a common disorder that is often unrecognized and underappreciated. Emerging evidence suggests that there is a causal link between obstructive sleep apnea and hypertension. This relationship appears to be independent of other comorbidities that have been previously linked to hypertension, suc...

journal_title：Current hypertension reports

authors： Phillips BG,Somers VK

更新日期：2003-10-01 00:00:00

abstract：:This review is focused on the interplay between two major factors affecting the vascular tree in diabetes, insulin resistance, and hyperglycemia. The implications for vascular function, structure, and the interaction between vascular cells and other tissues by which they are affected under these conditions are reviewe...

journal_title：Current hypertension reports

authors： Stern N,Marcus Y

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the most recent literature on current strategies for the treatment of hypertension associated with pediatric obesity. RECENT FINDINGS:Over the last three decades, childhood and adolescent overweight and obesity prevalence in the USA has continued to rise. Unsurprisingly but rather disturbin...

journal_title：Current hypertension reports

authors： Binka E,Brady TM

更新日期：2019-02-12 00:00:00

abstract：:Vascular changes associated with elevated blood pressure may precede the clinical diagnosis of hypertension. Even after the diagnosis is made, associated coronary heart disease and renal disease continue to progress, despite adequate blood pressure control. Early treatment of blood pressure may reduce the incidence of...

journal_title：Current hypertension reports

authors： Nesbitt SD,Julius S

更新日期：2000-08-01 00:00:00

abstract：:Albuminuria is an early marker for diabetic nephropathy in patients with diabetes, and has a clear place in patient care. It also predicts cardiovascular events and mortality in diabetic patients and in the general population, and is slowly becoming accepted in population screening for cardiovascular disease and chron...

journal_title：Current hypertension reports

authors： Bakker SJ,Gansevoort RT,de Zeeuw D

更新日期：2009-04-01 00:00:00

abstract：:Young hypertensive adults demonstrate decreased performance on neurocognitive testing compared with that of normotensive controls. There is emerging, preliminary evidence that children with hypertension also manifest cognitive differences when compared to normotensive controls. These preliminary studies consist mostly...

journal_title：Current hypertension reports

authors： Lande MB,Kupferman JC

更新日期：2015-01-01 00:00:00

abstract：:The incidence and prevalence of obesity and the metabolic syndrome have risen markedly in the past decade, representing a serious cardiovascular health hazard with significant morbidity and mortality. The etiology of the metabolic syndrome and its various pathogenic mechanisms are incompletely defined and under intens...

journal_title：Current hypertension reports

authors： Patel SB,Reams GP,Spear RM,Freeman RH,Villarreal D

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mechanisms facilitating progression of hypertension via cross stimulation of the renin-angiotensin system (RAS) and inflammation have been proposed. Accordingly, we review and update evidence for regulation of RAS components by pro-inflammatory factors. RECENT FINDINGS:Angiotensin II (Ang II), which ...

journal_title：Current hypertension reports

authors： Satou R,Penrose H,Navar LG

更新日期：2018-10-05 00:00:00

abstract：:Heart failure has emerged as one of the most important diseases of the past century. The understanding and treatment of heart failure has evolved significantly over the years. As we move further into the era of device therapy, attention has turned to the idea of sympathetic nervous system modulation through renal dene...

journal_title：Current hypertension reports

authors： Fong MW,Shavelle D,Weaver FA,Nadim MK

更新日期：2015-03-01 00:00:00

abstract：:Diabetes and hypertension are common coexistent conditions, the combination of which results in an increased risk for cardiovascular and renal disease. Clinical trials have convincingly demonstrated the benefit of tight blood pressure control among patients with diabetes in reducing these risks. Furthermore, the choic...

journal_title：Current hypertension reports

authors： Borzecki AM,Berlowitz DR

更新日期：2005-12-01 00:00:00

abstract：:The World Health Organization's annual report World Health Statistics 2012 was recently published. In addition to annually published indicators of health, this year's report contains a highlighted new section on non-communicable diseases and their impact on world health. The section gives particular attention to hyper...

journal_title：Current hypertension reports

authors： Owen J,Reisin E

更新日期：2012-12-01 00:00:00

abstract：:It is widely accepted that the pathophysiology of hypertension involves autonomic nervous system dysfunction, as well as a multitude of immune responses. However, the close interplay of these systems in the development and establishment of high blood pressure and its associated pathophysiology remains elusive and is t...

journal_title：Current hypertension reports

authors： Santisteban MM,Zubcevic J,Baekey DM,Raizada MK

更新日期：2013-08-01 00:00:00

abstract：:Current national guidelines recommend aggressive lowering of blood pressure (< 130/80 mm Hg) in patients with chronic kidney disease (CKD). In this paper, we summarize recent clinical trial data evaluating the effect of lower blood pressure goals on renal outcomes. The epidemiologic data relating blood pressure to pro...

journal_title：Current hypertension reports

authors： Rahman M,El-Meanawy A,Romanello J

更新日期：2005-10-01 00:00:00

abstract：:The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a watershed. Data demonstrate clearly that lowering blood pressure is the most important aspect of hypertension man...

journal_title：Current hypertension reports

authors： Wang JG,Staessen JA,Heagerty AM

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The intrarenal renin-angiotensin-aldosterone system (RAS) is an independent paracrine hormonal system with an increasingly prominent role in hypertension and renal disease. Two enzyme components of this system are angiotensin-converting enzyme (ACE) and more recently discovered ACE2. The purpose of th...

journal_title：Current hypertension reports

authors： Culver S,Li C,Siragy HM

更新日期：2017-09-19 00:00:00

abstract：:Obesity is recognized as a major health problem throughout the world. Excess weight is a major cause of increased blood pressure in most patients with essential hypertension and greatly increases the risk for diabetes, cardiovascular diseases, and end-stage renal disease. Although the mechanisms by which obesity raise...

journal_title：Current hypertension reports

authors： da Silva AA,do Carmo J,Dubinion J,Hall JE

更新日期：2009-06-01 00:00:00

abstract：:Hypertension is an important public health problem, and increasingly children are being diagnosed with primary hypertension. As the list of secondary causes of hypertension is extensive, pediatric practitioners increasingly need to decide on investigations needed for evaluating children presenting with high blood pres...

journal_title：Current hypertension reports

authors： Kapur G,Baracco R

更新日期：2013-10-01 00:00:00

abstract：:The renin-angiotensin system (RAS) plays an important role in the initiation and progression of tissue injuries in the cardiovascular and nervous systems. The detrimental actions of the AT1 receptor (AT1R) in hypertension and vascular injury, myocardial infarction and brain ischemia are well established. In the past t...

journal_title：Current hypertension reports

authors： Namsolleck P,Recarti C,Foulquier S,Steckelings UM,Unger T

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This is a review of available data on the effects of blood pressure and statins on cognition. RECENT FINDINGS:Recent randomized clinical trials have shown that intensive control of systolic blood pressure in older adults prevented the development of mild cognitive impairment (MCI) and the combined ef...

journal_title：Current hypertension reports

authors： Yang M,Williamson J

更新日期：2019-07-26 00:00:00

abstract：:Obstructive sleep apnea (OSA) is a prevalent sleep disorder which is characterized by recurrent upper closure with oxygen desaturation and sleep disruption. OSA increases the risk of vascular disorders in the form of stroke, myocardial infarction, congestive heart failure, and hypertension. The mechanisms underlying t...

journal_title：Current hypertension reports

authors： Mohsenin V

更新日期：2014-10-01 00:00:00

abstract：:Primary aldosteronism (PA) is a common cause of arterial hypertension: in the PA Prevalence in Hypertensives (PAPY) Study, the prevalence of PA was 11.2% in consecutive referred hypertensive patients. When adrenal vein sampling (AVS) is available, two thirds of the cases can be attributed to a tumor and one third of c...

journal_title：Current hypertension reports

authors： Rossi GP

更新日期：2010-10-01 00:00:00

abstract：:Hypertension is a major cause of morbidity and mortality worldwide. Despite a myriad of oral agents, many patients fail to reach their target blood pressure. Electrical stimulation of the carotid sinus, an old therapeutic concept, lowers blood pressure by initiating the baroreflex and reducing sympathetic tone. Recent...

journal_title：Current hypertension reports

authors： Filippone JD,Sloand JA,Illig KA,Bisognano JD

更新日期：2006-10-01 00:00:00

abstract：:Endothelin receptor antagonists (ERAs) have the potential to be a new paradigm in the treatment of chronic kidney disease (CKD). ERAs inhibit the effects of endothelin-1 (ET-1), which is known to promote CKD by causing renal cellular injury, proteinuria, inflammation, fibrosis, and hypertrophy. ERAs have been extensiv...

journal_title：Current hypertension reports

authors： Tobe S,Kohan DE,Singarayer R

更新日期：2015-07-01 00:00:00

abstract：:The kidneys play a central role in the long-term regulation of blood pressure and in the pathogenesis of hypertension. A common defect that has been found in all forms of hypertension examined to date is a hypertensive shift in the pressure-natriuresis relationship. A major objective of this brief review is to highlig...

journal_title：Current hypertension reports

authors： Granger JP,Abram S,Stec D,Chandler D,LaMarca B

更新日期：2006-08-01 00:00:00

abstract：:The treatment of hypertension is proven to reduce cardiovascular and renal risk. Combination drug therapy is becoming recognized as a necessity in most patients with hypertension and kidney disease. Allegations about the safe use of calcium antagonists in patients with kidney disease have led to questions and confusio...

journal_title：Current hypertension reports

authors： Tobe S,Epstein M

更新日期：2002-06-01 00:00:00

abstract：:The central nervous system plays a key role in the regulation of cardiovascular function, and alterations in the central neural mechanisms that control blood pressure may underlie the vast majority of cases of primary hypertension. The well-studied baroreceptor reflex powerfully regulates arterial pressure, though its...

journal_title：Current hypertension reports

authors： Sved AF,Ito S,Sved JC

更新日期：2003-06-01 00:00:00

abstract：:Decreased endothelial nitric oxide (NO) bioavailability as it relates to endothelial dysfunction plays an important role in various cardiovascular disorders, including athero-sclerosis. Recent research has provided evidence that endothelial dysfunction in atherosclerosis is not primarily caused by decreased endothelia...

journal_title：Current hypertension reports

authors： Yang Z,Ming XF

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Renal sympathetic denervation (RDN) as treatment option for hypertension has a strong rationale; however, variable effects on blood pressure (BP) have been reported ranging from non-response to marked reductions in BP. The absence of a procedural end point for RDN is one of the potential factors assoc...

journal_title：Current hypertension reports

authors： Hoogerwaard AF,de Jong MR,Elvan A

更新日期：2018-03-19 00:00:00

abstract：:The discovery of angiotensin-converting enzyme (ACE) 2 adds a new level of complexity to the understanding of the renin-angiotensin system. The high catalytic efficiency of ACE2 for the generation of angiotensin (ANG)-1-7 from ANG II suggests an important role of ACE2 in preventing ANG II accumulation, while at the sa...

journal_title：Current hypertension reports

authors： Wysocki J,González-Pacheco FR,Batlle D

更新日期：2008-02-01 00:00:00