Genotoxic effects of Tabebuia impetiginosa (Mart. Ex DC.) Standl. (Lamiales, Bignoniaceae) extract in Wistar rats.

abstract：:Hereditary cancer risk assessment is a multidisciplinary and dynamic process, with the purpose of estimating probabilities of germline mutations in cancer susceptibility genes and assessing empiric risks of cancer based on personal and family histories, in order to offer clinical and molecular diagnoses and clinical m...

journal_title：Genetics and molecular biology

authors： Gomy I,Diz Mdel P

更新日期：2016-05-13 00:00:00

abstract：:Breast cancer (BC) is the most prevalent type worldwide, besides being one of the most common causes of death among women. It has been suggested that sporadic BC is most likely caused by low-penetrance genes, including those involved in DNA repair mechanisms. Furthermore, the accumulation of DNA damage may contribute ...

journal_title：Genetics and molecular biology

authors： Santos RA,Teixeira AC,Mayorano MB,Carrara HH,Andrade JM,Takahashi CS

更新日期：2010-10-01 00:00:00

abstract：:Genetic variation was estimated in ten samples populations of Aedes aegypti from the Brazilian Amazon, by using a 380 bp fragment of the mitochocondrial NADH dehydrogenase subunit 4 (ND4) gene. A total of 123 individuals were analyzed, whereby 13 haplotypes were found. Mean genetic diversity was slightly high (h = 0.6...

journal_title：Genetics and molecular biology

authors： Lima RS Jr,Scarpassa VM

更新日期：2009-04-01 00:00:00

abstract：:Ample evidence suggests that cancer is triggered by mutagenic damage and diets or supplements capable of reducing such incidences can be related to the prevention of neoplasy development or to an improvement in life quality of patients who undergo chemotherapy. This research aimed to evaluate the antimutagenic and ant...

journal_title：Genetics and molecular biology

authors： Oliveira RJ,Salles MJ,da Silva AF,Kanno TY,Lourenço AC,Leite Vda S,Matiazi HJ,Pesarini JR,Ribeiro LR,Mantovani MS

更新日期：2013-09-01 00:00:00

abstract：:Up-regulation of human endogenous retroviruses (HERVs) is associated with many diseases, including cancer. In this study, an H family HERV (HERV-H)-related gene was identified and characterized. Its spliced transcript lacks protein-coding capacity and may belong to the emerging class of noncoding RNAs (ncRNAs). The 1....

journal_title：Genetics and molecular biology

authors： Liang Q,Ding J,Zheng S

更新日期：2009-10-01 00:00:00

abstract：:Seven polymorphic microsatellite loci were isolated and characterized for the snakehead murrel, Channa striata (Channidae), a valuable tropical freshwater fish species. Among 25 specimens collected from Kedah state in Malaysia, the number of alleles per locus ranged from 2 to 7. Observed and expected heterozygosities ...

journal_title：Genetics and molecular biology

authors： Jamsari AF,Min-Pau T,Siti-Azizah MN

更新日期：2011-04-01 00:00:00

abstract：:The goal of this research was to investigate the linkage disequilibrium between rs9263726 and HLA-B*58:01 in different Chinese ethnic groups (Han, Tibet, and Hui) and to study the feasibility of rs9263726 replacing HLA-B*58:01 as an efficient indicator of potential allopurinol hypersensitivity syndrome. In this study,...

journal_title：Genetics and molecular biology

authors： Zhang X,Jin L,Wu Z,Ma W,Chen Y,Chen G,Wang L,Guan M

更新日期：2018-07-01 00:00:00

abstract：:Splicing, the process that catalyzes intron removal and flanking exon ligation, can occur in different ways (alternative splicing) in immature RNAs transcribed from a single gene. In order to adapt to a particular context, cells modulate not only the quantity but also the quality (alternative isoforms) of their transc...

journal_title：Genetics and molecular biology

authors： Botto AEC,Muñoz JC,Giono LE,Nieto-Moreno N,Cuenca C,Kornblihtt AR,Muñoz MJ

更新日期：2020-03-27 00:00:00

abstract：:Heat shock (HS) leads to the activation of molecular mechanisms, known as HS-response, that prevent damage and enhance survival under stress. Plants have a flexible and specialized network of Heat Shock Factors (HSFs), which are transcription factors that induce the expression of heat shock proteins. The present work ...

journal_title：Genetics and molecular biology

authors： Soares-Cavalcanti NM,Belarmino LC,Kido EA,Pandolfi V,Marcelino-Guimarães FC,Rodrigues FA,Pereira GA,Benko-Iseppon AM

更新日期：2012-06-01 00:00:00

abstract：:Trypoxylon is a genus of solitary crabronid wasps whose population genetics is poorly known. The purpose of the present study was to investigate the genetic variation and differentiation among five populations of Trypoxylon albitarse, a species widely distributed throughout the Neotropics, with records from Panama to ...

journal_title：Genetics and molecular biology

authors： Bergamaschi AC,Lama MA

更新日期：2015-12-01 00:00:00

abstract：:Rhagomys rufescens (Rodentia: Sigmodontinae) is an endemic species of the Atlantic forest from Southern and Southeastern Brazil. Some authors consider Rhagomys as part of the tribe Thomasomyini; but its phylogenetic relationships remain unclear. Chromosomal studies on eight specimens of Rhagomys rufescens revealed a d...

journal_title：Genetics and molecular biology

authors： Testoni AF,Althoff SL,Nascimento AP,Steiner-Souza F,Sbalqueiro IJ

更新日期：2010-07-01 00:00:00

abstract：:Population genetics studies the distributions and changes in population allele frequencies in response to processes, such as mutation, natural selection, gene flow, and genetic drift. Researchers daily manage genetic, biological, and environmental data of the samples, storing them in text files or spreadsheets, which ...

journal_title：Genetics and molecular biology

authors： Elias DE,Rueda ECR

更新日期：2020-05-29 00:00:00

abstract：:The applicability of mitochondrial nad6 sequences to studies of DNA and population variability in Lepidoptera was tested in four species of economically important moths and one of wild butterflies. The genetic information so obtained was compared to that of cox1 sequences for two species of Lepidoptera. nad6 primers a...

journal_title：Genetics and molecular biology

authors： Silva-Brandão KL,Lyra ML,Santos TV,Seraphim N,Albernaz KC,Pavinato VA,Martinelli S,Cônsoli FL,Omoto C

更新日期：2011-10-01 00:00:00

abstract：:Xylella fastidiosa genome sequencing has generated valuable data by identifying genes acting either on metabolic pathways or in associated pathogenicity and virulence. Based on available information on these genes, new strategies for studying their expression patterns, such as microarray technology, were employed. A t...

journal_title：Genetics and molecular biology

authors： Travensolo RF,Carareto-Alves LM,Costa MV,Lopes TJ,Carrilho E,Lemos EG

更新日期：2009-04-01 00:00:00

abstract：:The population of India harbors one of the world's most highly diverse gene pools, owing to the influx of successive waves of immigrants over regular periods in time. Several phylogenetic studies involving mitochondrial DNA and Y chromosomal variation have demonstrated Europeans to have been the first settlers in Indi...

journal_title：Genetics and molecular biology

authors： Tiwari SK,Sharma V,Sharma VK,Gopi M,Saikant R,Nandan A,Bardia A,Gunisetty S,Katikala P,Habeeb MA,Khan AA,Habibullah CM

更新日期：2011-04-01 00:00:00

abstract：:Cannabinoids, flavonoids, and stilbenoids have been identified in the annual dioecious plant Cannabis sativa L. Of these, the cannabinoids are the best known group of this plant's natural products. Polyketide synthases (PKSs) are responsible for the biosynthesis of diverse secondary metabolites, including flavonoids a...

journal_title：Genetics and molecular biology

authors： Flores-Sanchez IJ,Linthorst HJ,Verpoorte R

更新日期：2010-10-01 00:00:00

abstract：:The decapod Grapsus grapsus is commonly found on oceanic islands of the Pacific and Atlantic coasts of the Americas. In this study, a simple, quick and reliable method for detecting its larvae in plankton samples is described, which makes it ideal for large-scale studies of larval dispersal patterns in the species. ...

journal_title：Genetics and molecular biology

authors： Ströher PR,Firkowski CR,Freire AS,Pie MR

更新日期：2011-07-01 00:00:00

abstract：:Human longevity is a polygenic and multifactorial trait. Pathways related to lifespan are complex and involve molecular, cellular, and environmental processes. In this analytical observational study, we evaluated the relationship between environment factors, oxidative stress status, DNA integrity level, and the associ...

journal_title：Genetics and molecular biology

authors： Silva-Sena GG,Camporez D,Santos LRD,Silva ASD,Sagrillo Pimassoni LH,Tieppo A,Pimentel Batitucci MDC,Morelato RL,Paula F

更新日期：2018-04-01 00:00:00

abstract：:Epidermal growth factor (EGF), a multifunctional growth factor, is a regulator in a wide variety of physiological processes. EGF plays an important role in the regulation of liver regeneration. This study was aimed at investigating the methylation level of EGF gene throughout liver regeneration. DNA of liver tissue fr...

journal_title：Genetics and molecular biology

authors： Li D,Fan J,Li Z,Xu C

更新日期：2014-06-01 00:00:00

abstract：:For a study of diversity and genetic structuring in Melipona quadrifasciata, 61 colonies were collected in eight locations in the state of Minas Gerais, Brazil. By means of PCR analysis, 119 ISSR bands were obtained, 80 (68%) being polymorphic. H(e) and H (B) were 0.20 and 0.16, respectively. Two large groups were obt...

journal_title：Genetics and molecular biology

authors： Nascimento MA,Batalha-Filho H,Waldschmidt AM,Tavares MG,Campos LA,Salomão TM

更新日期：2010-04-01 00:00:00

abstract：:MicroRNAs are considered as potential biomarkers, agents, or therapeutic targets; few studies have addressed the expression of miRNAs in treatment-naïve patients infected with HIV-1. The aim of this study was to assess plasma relative circulating miRNA expression profiles in treatment-naïve Mexican patients with HIV/A...

journal_title：Genetics and molecular biology

authors： Cárdenas-Bedoya J,Marquez-Pedroza J,Morán-Moguel MC,Escoto-Delgadillo M,Vázquez-Valls E,González-Enríquez GV,Pérez-Ríos AM,Torres-Mendoza BM

更新日期：2020-06-22 00:00:00

abstract：:The Morato's Digger Toad, Proceratophrys moratoi, is a critically endangered toad species with a marked population decline in southern Brazilian Cerrado. Despite this, new populations are being discovered, primarily in the northern part of the distribution range, which raises a number of questions with regard to the c...

journal_title：Genetics and molecular biology

authors： Arruda MP,Costa WP,Recco-Pimentel SM

更新日期：2017-04-01 00:00:00

abstract：:A 10-year-old speechless, mentally deficient male, with low arylsulfatase A (ARSA) activity, and presumably, methachromatic leukodystrophy, underwent genetic evaluation. As the clinical picture was not compatible with this diagnosisan ARSA gene and chromosome analysis were performed, showing the presence of a pseudode...

journal_title：Genetics and molecular biology

authors： Artigalás O,Paskulin G,Riegel M,Burin M,Saraiva-Pereira ML,Maluf S,Kiss A,Schwartz IV

更新日期：2012-04-01 00:00:00

abstract：:The potential effect of electromagnetic fields (EMFs) emitted from video display terminals (VDTs) to elicit biological response is a major concern for the public. The software professionals are subjected to cumulative EMFs in their occupational environments. This study was undertaken to evaluate DNA damage and inciden...

journal_title：Genetics and molecular biology

authors： Lakshmi N,Tiwari R,Bhargava S,Ahuja Y

更新日期：2010-01-01 00:00:00

abstract：:Meiotic and mitotic chromosomes of Dichotomius nisus, D. semisquamosus and D. sericeus were analyzed after conventional staining, C-banding and silver nitrate staining. In addition, Dichotomius nisus and D. semisquamosus chromosomes were also analyzed after fluorescent in situ hybridization (FISH) with an rDNA probe. ...

journal_title：Genetics and molecular biology

authors： da Silva GM,Bione EG,Cabral-de-Mello DC,de Moura Rde C,Simões ZL,de Souza MJ

更新日期：2009-04-01 00:00:00

abstract：:Birth defects (BDs) are functional and structural alterations in embryonic or fetal development. With an incidence of approximately 3-5%, BDs are a leading cause of infant mortality and lifelong disability. A population-based prospective case-control study was conducted for one year with 5204 infants, between March 1s...

journal_title：Genetics and molecular biology

authors： Oliveira-Brancati CIF,Ferrarese VCC,Costa AR,Fett-Conte AC

更新日期：2020-02-10 00:00:00

abstract：:Alcohol dehydrogenases belong to the large superfamily of medium-chain dehydrogenases/reductases, which occur throughout the biological world and are involved with many important metabolic routes. We considered the phylogeny of 190 ADH sequences of animals, fungi, and plants. Non-class III Caenorhabditis elegans ADHs ...

journal_title：Genetics and molecular biology

authors： Thompson CE,Freitas LB,Salzano FM

更新日期：2018-01-01 00:00:00

abstract：:Phylogenetic niche conservatism can be investigated at multiple scales on an explicit geographical context. Haplotype-based comparative analyses of lineages occupying the same region, and thus subjected to similar environmental factors, allow decoupling shared evolutionary and ecological patterns, as well as multiple ...

journal_title：Genetics and molecular biology

authors： Barros MJF,Silva-Arias GA,Segatto ALA,Reck-Kortmann M,Fregonezi JN,Diniz-Filho JAF,Freitas LB

更新日期：2020-04-27 00:00:00

abstract：:The arylamine N-acetyltransferase 2 (NAT2) enzymes detoxify a wide range of naturally occurring xenobiotics including carcinogens and drugs. Point mutations in the NAT2 gene result in the variant alleles M1 (NAT2 *5A), M2 (NAT2*6A), M3 (NAT2*7) and M4 (NAT2 *14A) from the wild-type WT (NAT2 *4) allele. The current stu...

journal_title：Genetics and molecular biology

authors： Mahasneh A,Jubaili A,El Bateiha A,Al-Ghazo M,Matalka I,Malkawi M

更新日期：2012-12-01 00:00:00

abstract：:During the last decade, microsatellites (short tandem repeats or STRs) have been successfully used for animal genetic identification, traceability and paternity, although in recent year single nucleotide polymorphisms (SNPs) have been increasingly used for this purpose. An efficient SNP identification system requires ...

journal_title：Genetics and molecular biology

authors： Fernández ME,Goszczynski DE,Lirón JP,Villegas-Castagnasso EE,Carino MH,Ripoli MV,Rogberg-Muñoz A,Posik DM,Peral-García P,Giovambattista G

更新日期：2013-07-01 00:00:00