Abstract:
PURPOSE:Arterial hyperoxia after resuscitation has been associated with increased mortality in adults. The aim of this study was to test the hypothesis that post-resuscitation hyperoxia and hypocapnia are associated with increased mortality after resuscitation in pediatric patients. METHODS:We performed a prospective observational multicenter hospital-based study including 223 children aged between 1 month and 18 years who achieved return of spontaneous circulation after in-hospital cardiac arrest and for whom arterial blood gas analysis data were available. RESULTS:After return of spontaneous circulation, 8.5% of patients had hyperoxia (defined as PaO(2)>300 mm Hg) and 26.5% hypoxia (defined as PaO(2)<60 mm Hg). No statistical differences in mortality were observed when patients with hyperoxia (52.6%), hypoxia (42.4%), or normoxia (40.7%) (p=0.61). Hypocapnia (defined as PaCO(2)<30 mm Hg) was observed in 13.5% of patients and hypercapnia (defined as PaCO(2)>50 mm Hg) in 27.6%. Patients with hypercapnia or hypocapnia had significantly higher mortality (59.0% and 50.0%, respectively) than patients with normocapnia (33.1%) (p=0.002). At 24h after return of spontaneous circulation, neither PaO(2) nor PaCO(2) values were associated with mortality. Multiple logistic regression analysis showed that hypercapnia (OR, 3.27; 95% CI, 1.62-6.61; p=0.001) and hypocapnia (OR, 2.71; 95% CI, 1.04-7.05; p=0.04) after return of spontaneous circulation were significant mortality factors. CONCLUSIONS:In children resuscitated from cardiac arrest, hyperoxemia after return of spontaneous circulation or 24h later was not associated with mortality. On the other hand, hypercapnia and hypocapnia were associated with higher mortality than normocapnia.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Del Castillo J,López-Herce J,Matamoros M,Cañadas S,Rodriguez-Calvo A,Cechetti C,Rodriguez-Núñez A,Alvarez AC,Iberoamerican Pediatric Cardiac Arrest Study Network RIBEPCI.doi
10.1016/j.resuscitation.2012.07.019subject
Has Abstractpub_date
2012-12-01 00:00:00pages
1456-61issue
12eissn
0300-9572issn
1873-1570pii
S0300-9572(12)00376-0journal_volume
83pub_type
杂志文章,多中心研究相关文献
RESUSCITATION文献大全abstract:AIM:The aim of this study was to calculate the incidence of out-of-hospital cardiac arrest (OHCA) in primary health care in Greece and assess general practitioners' (GPs) willingness towards the use of automatic external defibrillator (AED). METHODS:We conducted a survey in GPs working in both private and public secto...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.04.010
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Cardiac arrest (CA) without return of spontaneous circulation can be treated with veno-arterial extracorporeal membrane oxygenation (vaECMO) implemented surgically or percutaneously. We performed a study assessing time for vaECMO percutaneous cannulation in the catheterization laboratory. METHODS:Single-cen...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.11.057
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Therapeutic hypothermia (TH) is standard of care after ventricular fibrillation cardiac arrest (CA). Continuous EEG monitoring (cEEG) is increasingly used during TH. Analysis regarding value of cEEG utilization in this population in the context of cost and outcome has not been performed. We compared outcom...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.01.019
更新日期:2014-06-01 00:00:00
abstract:AIM:To determine the number of CPR trained adults in Sweden, and the willingness of the non-trained population to attend a CPR course. An additional purpose was to investigate differences related to sex, age, residential area, socio-economic classification and country of origin. METHODS:Five thousand adults in Sweden ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.11.009
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Extra-corporeal life support (ECLS) is a life-saving intervention for patients with hypothermia induced cardiac arrest or severe cardiovascular instability. However, its application is highly variable due to a paucity of data in the literature to guide practice. Current guidelines and recommendations are bas...
journal_title:Resuscitation
pub_type: 杂志文章,meta分析
doi:10.1016/j.resuscitation.2018.03.028
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:For children with out-of-hospital cardiac arrest, previous observational studies regarding chest-compression-only CPR (CC-CPR) versus conventional CPR yielded inconsistent results. We aimed to summarize the current evidence and compare the outcomes after CC-CPR with those after conventional CPR by bystanders...
journal_title:Resuscitation
pub_type: 杂志文章,meta分析
doi:10.1016/j.resuscitation.2018.10.032
更新日期:2019-01-01 00:00:00
abstract::The time course of Procalcitonin (PCT) serum levels was assessed in cardiac arrest survivors and compared with S-100 serum levels concerning their predictive values for neurological outcome. PCT and S-100 serum levels were analyzed serially on admission and during the following 3 days after hospitalization in 23 patie...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(03)00164-3
更新日期:2003-10-01 00:00:00
abstract:AIM:We sought to examine whether the outcomes of out-of-hospital cardiopulmonary arrest (OHCA) patients differed between weekday and weekend/holiday admissions, or between daytime and nighttime admissions. METHODS:From a national registry of OHCA events in Japan between 2005 and 2008, 173,137 cases where the call-to-h...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2011.02.007
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of strategies to reduce the spread of simulated aerosol during chest compressions on manikin and cadaver experimental models. METHODS:To evaluate aerosol-spread we nebulized ultraviolet sensitive detergents into the artificial airway of a resuscitation dummy and performed CPR. The spre...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2020.05.012
更新日期:2020-07-01 00:00:00
abstract::Serum lactic acidosis is characterized by a pH less than 7.25 and lactate greater than 5 mEq. Although sodium bicarbonate (NaHCO3) is standard treatment for this condition, clinical and experimental studies suggest that high doses of NaHCO3 may be ineffectual or even detrimental to brain, cardiovascular, and respirato...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(88)90015-9
更新日期:1988-01-01 00:00:00
abstract:AIM OF THE STUDY:Regionalization of care for out-of-hospital cardiac arrests (OHCA) may improve patient outcomes. We evaluated inter-hospital variations in post-arrest care provision and the relation between hospital case volume and survival in Pennsylvania. METHODS:This retrospective study (2013-2017) used data from ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.02.004
更新日期:2019-04-01 00:00:00
abstract:AIM:To assess the effectiveness of the ILCOR Advisory Statements on Advanced Life Support adopted by the Resuscitation Council (UK), as the standard for resuscitation following cardiac arrest. METHOD:Over the period May to November 1997, data on the process and outcome of cardiopulmonary resuscitation following in-hos...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(00)00212-4
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:Cardiac arrest (CA) is a rare but recognized complication of emergency airway management. Our aim was to measure the incidence of peri-intubation CA during emergency intubation and identify factors associated with this complication. METHODS:Retrospective cohort study of emergency endotracheal intubations per...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.07.022
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:"Calling for help, performing first aid and providing Cardiopulmonary Resuscitation (CPR)" is part of the educational goals in secondary schools in Belgium (Flanders). However, for teachers it is not always clear at what age children can be taught which aspects of first aid. In addition, it is not clear what...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2015.06.008
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:the objective was to determine clinical characteristics that can quickly distinguish sudden death from massive pulmonary embolism (MPE) from other causes of sudden death. METHODS AND RESULTS:all medical examiner reports from Charlotte, NC from 1992 to 1999 (n=4926) were hand-searched for cases of sudden dea...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(00)00374-9
更新日期:2001-06-01 00:00:00
abstract:AIM:Besides supportive care, the only recommended treatment for comatose patients after cardiac arrest is target temperature management. Helium reduces ischaemic injury in animal models, and might ameliorate neurological injury in patients after cardiac arrest. As no studies exist on the use of helium in patients after...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.07.004
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:Although the survival rate after out-of-hospital cardiac arrest (OHCA) has increased over time, little is known about the return to work of OHCA survivors. We aim to evaluate prevalence and factors associated with return to work (RTW) in OHCA survivors. PATIENTS AND METHODS:All consecutive OHCA survivors ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2018.05.021
更新日期:2018-07-01 00:00:00
abstract:AIM:Few data are available on the use of brainstem auditory evoked potentials (BAEPs) in combination with other electrophysiological tools to assess prognosis of comatose survivors from cardiac arrest (CA). METHODS:Retrospective analysis of data from all adult patients (>18years of age) admitted to our Dept of Intensi...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.09.013
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION:Clinical teams struggle on general wards with acute management of deteriorating patients. We hypothesized that the Crisis Checklist App, a mobile application containing checklists tailored to crisis-management, can improve teamwork and acute care management. METHODS:A before-and-after study was undertaken...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2020.09.031
更新日期:2020-12-01 00:00:00
abstract::If sudden cardiac arrest occurs during cardiac catheterization, the underlying coronary condition may be defined immediately by coronary angiography. This may, in turn, allow a lifesaving attempt of percutaneous coronary intervention (PCI). We report on two patients with critical proximal disease of the left coronary ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2003.12.020
更新日期:2004-05-01 00:00:00
abstract::Despite recent advances in its management, the outcome from cardiac arrest is often poor despite appropriate cardiopulmonary resuscitation (CPR). The coronary perfusion pressure (CPP) achieved during CPR is associated with successful return of spontaneous circulation (ROSC). Continuous balloon occlusion of the descend...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.10.017
更新日期:2009-02-01 00:00:00
abstract::Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation acute myocardial infarction (STEMI). In comatose survivors of cardiac arrest, mild induced hypothermia (MIH) improves neurological recovery. In the present study, we investigated feasibility and safety of combining ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.01.016
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Despite its prevalence, survival from out-of-hospital cardiac arrest remains low. High quality CPR has been associated with improved survival in cardiac arrest patients. In early 2014, a program was initiated to provide feedback on CPR quality to prehospital providers after every treated cardiac arrest. OBJ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.02.004
更新日期:2017-04-01 00:00:00
abstract:AIM OF STUDY:Few published "track and trigger systems" used to identify sick adult patients incorporate patient age as a variable. We investigated the relationship between vital signs, patient age and in-hospital mortality and investigated the impact of patient age on the function as predictors of in-hospital mortality...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.03.004
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Previous studies have reported regional variation in either the incidence or outcomes of sepsis or In-hospital Cardiac Arrest (IHCA) discretely; however, regional variations in the incidence and outcomes of sepsis-associated IHCA (SA-IHCA) have never been studied. METHODS:From the National Inpatient Sample ...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2019.08.007
更新日期:2019-10-01 00:00:00
abstract::We have reported the finding of numerous spiculed erythrocytes in blood stored for 15-21 days with acid citrate dextrose, drawing attention to the possible decrease of stored red cell deformability because of the decrease of the surface to volume ratio. The presence of anisotropy with crenated spheres, equivalent to t...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(83)90032-1
更新日期:1983-08-01 00:00:00
abstract::This study was undertaken to determine if checking for a pulse between initial defibrillations causes a clinically significant delay in the administration of the defibrillations. Ten emergency department nurses and 10 emergency medicine resident physicians were timed delivering three successive defibrillations (200, 3...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0300-9572(96)01043-x
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:It is still under debate whether a period of cardiopulmonary resuscitation should be performed prior to rhythm analysis for defibrillation for out of hospital cardiac arrests (OHCA). This study compared outcomes of OHCA treated by "compression first" (CF) versus "analyze first" (AF) strategies in an Asian co...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2012.01.009
更新日期:2012-07-01 00:00:00
abstract:AIMS:Cardiopulmonary resuscitation is one of the most vital therapeutic options for patients with cardiac arrest. Sufficient chest compression depth turned out to be of utmost importance to increase the likelihood of a return of spontaneous circulation. Furthermore, the use of real-time feedback-systems for resuscitati...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.12.030
更新日期:2014-04-01 00:00:00
abstract::During the many emergency situations in which venous access is difficult or impossible, endotracheal drug administration is an effective alternative means of delivering life-saving medications. Shock is a commonly encountered emergency situation in which endotracheal drug therapy can and is often used. Yet whether a d...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(90)90108-q
更新日期:1990-06-01 00:00:00