Abstract:
:Genome-wide association studies (GWAS) have become a widely used approach for genetic association studies of various human traits. A few GWAS have been conducted with the goal of identifying novel loci for pigmentation traits, melanoma, and non-melanoma skin cancer. Nevertheless, the phenotype variation explained by the genetic markers identified so far is limited. In this review, we discuss the GWAS study design and its application in pigmentation and skin cancer research. Furthermore, we summarize recent developments in post-GWAS activities such as meta-analysis, pathway analysis, and risk prediction.
journal_name
Pigment Cell Melanoma Resjournal_title
Pigment cell & melanoma researchauthors
Meng S,Zhang M,Liang L,Han Jdoi
10.1111/j.1755-148X.2012.01023.xsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
612-7issue
5eissn
1755-1471issn
1755-148Xjournal_volume
25pub_type
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