Abstract:
:In this essay I describe my personal journey from reductionist to systems cell biology and describe how this in turn led to a 3-year sea voyage to explore complex ocean communities. In describing this journey, I hope to convey some important principles that I gleaned along the way. I realized that cellular functions emerge from multiple molecular interactions and that new approaches borrowed from statistical physics are required to understand the emergence of such complex systems. Then I wondered how such interaction networks developed during evolution. Because life first evolved in the oceans, it became a natural thing to start looking at the small organisms that compose the plankton in the world's oceans, of which 98% are … individual cells-hence the Tara Oceans voyage, which finished on 31 March 2012 in Lorient, France, after a 60,000-mile around-the-world journey that collected more than 30,000 samples from 153 sampling stations.
journal_name
Mol Biol Celljournal_title
Molecular biology of the cellauthors
Karsenti Edoi
10.1091/mbc.E11-06-0571subject
Has Abstractpub_date
2012-07-01 00:00:00pages
2403-6issue
13eissn
1059-1524issn
1939-4586pii
23/13/2403journal_volume
23pub_type
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