Abstract:
:A hypoxic model was used to investigate changes in localized cerebral and muscle haemodynamics during knee extension (KE) in healthy individuals. Thirty-one young healthy volunteers performed one set of KE until failure under hypoxia (14 % O(2)) or normoxia (21 % O(2)) at 50, 75 or 100 % of 1 repetition maximum, in random order, on three occasions. Prefrontal cerebral and vastus lateralis muscle oxygenation and blood volume (Cox, Mox, Cbv and Mbv, respectively) were recorded simultaneously by near-infrared spectroscopy. Hypoxia induced significant declines in Cox [-0.017 ± 0.016 optical density (OD) units] and Mox (-0.014 ± 0.026 OD units) and increases in Cbv (0.017 ± 0.027 OD units) and Mbv (0.016 ± 0.023 OD units) at rest. Hypoxia significantly reduced total work (TW) performed during KE at each exercise intensity. Cox, Cbv, Mox, and Mbv changes during KE did not differ between normoxia and hypoxia. Correlations between TW done and Cox changes under normoxia (r = 0.04, p = 0.182) and hypoxia (r = 0.05, p = 0.122) were not significant. However, TW was significantly correlated with Mox under both normoxia (R (2) = 0.24, p = 0.000) and hypoxia (R (2) = 0.15, p = 0.004). Since changes in Cox and Mox reflect alterations in the balance between oxygen delivery and extraction in these tissues, which, in the brain, is an index of neuronal activation, we conclude that: (1) limitation of KE performance was mediated peripherally under both normoxia and hypoxia, with no additional effect of hypoxia, and (2) because of the low common variance with Mox additional intramuscular factors likely play a role in limiting KE performance.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Gomes PS,Matsuura C,Bhambhani YNdoi
10.1007/s00421-012-2408-7subject
Has Abstractpub_date
2013-01-01 00:00:00pages
13-23issue
1eissn
1439-6319issn
1439-6327journal_volume
113pub_type
杂志文章abstract::The purpose of this study was to assess cardiac function and arteriovenous oxygen difference (a-vO(2) difference) at rest and during exercise in young, normal-weight (n = 20), and obese (n = 12) men and women who were matched for age and fitness level. Participants were assessed for body composition, peak oxygen consu...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-010-1554-z
更新日期:2011-06-01 00:00:00
abstract::Triglyceride-rich postprandial lipoproteins are known to activate endothelial cells in vitro, contributing to atherosclerosis. Endothelial microparticles (EMP) are membranous vesicles released into the circulation from vascular endothelial cells that permit cell activation to be monitored in vivo. The objective of the...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-009-1050-5
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the effect of repeated bouts of eccentric exercise on the nociceptive withdrawal reflex (NWR) threshold, a measure of sensitivity in the spinal nociceptive system. METHODS:Sixteen healthy students (age 25.7 ± 0.6 years, BMI 24.8 ± 1 kg m(-2)) participated in this ra...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00421-013-2701-0
更新日期:2013-10-01 00:00:00
abstract::In this study, we compared the biomechanical and physiological responses of healthy men and women during bilateral load carriage while they walked on a treadmill at their self-selected velocity. Eleven men mean (SD) maximal oxygen uptake, [VO(2)(max) = 56.0 (7.1) ml x kg(-1) x min(-1)] and 11 women [VO(2)(max) = 44.6 ...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/PL00013800
更新日期:2000-01-01 00:00:00
abstract::Exercise is linked with intensity-dependent immune response. Intracellular redox status is important in programmed cell death. This study, by closely examining 18 sedentary men who exercised moderately and severely (ie. 60% and 80% VO2max, respectively) for 40 min, investigated how exercise intensities influence intra...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-0005-8
更新日期:2005-10-01 00:00:00
abstract::Both physical as well as mental demands result in an increased activity in the sympathetic nervous system (SNS) with changes in blood-pressure and heart-rate. Through local release of catecholamines, e.g. noradrenaline (NAd) SNS exerts various actions at the muscle level. The aims of this study were to investigate the...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-009-1095-5
更新日期:2009-09-01 00:00:00
abstract::All studies on the oxygen uptake (VO2) slow component have been carried out for the sporting disciplines of cycling or running, but never for swimming. Considering that front crawl swimming is a sport discipline that is fundamentally different from both running and cycling, the aim of this study was to verify whether ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s004210000348
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:Long static or intense dynamic apnoea-like high-altitude exposure is inducing hypoxia. Adenosine is known to participate to the adaptive response to hypoxia leading to the control of heart rate, blood pressure and vasodilation. Extracellular adenosine level is controlled through the equilibrative nucleoside tra...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-020-04523-1
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To examine the effects of the world's most challenging mountain ultra-marathon (Tor des Géants(®) 2012) on the energy cost of three types of locomotion (cycling, level and uphill running) and running kinematics. METHODS:Before (pre-) and immediately after (post-) the competition, a group of ten male experience...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-014-2824-y
更新日期:2014-05-01 00:00:00
abstract::Contribution of skin thermal sensors under inert gas narcosis to the raising hypothermia is not known. Such information is vital for understanding the impact of narcosis on behavioural thermoregulation, diver safety and judgment of thermal (dis)comfort in the hyperbaric environment. So this study aimed at establishing...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-011-2169-8
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:A critical limitation with transcutaneous neuromuscular electrical stimulation is the rapid onset of muscle fatigue. We have previously demonstrated that spatially distributed sequential stimulation (SDSS) shows a drastically greater fatigue-reducing ability compared to a single active electrode stimulation (SE...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-013-2807-4
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Besides mechanical loading of the back, physiological strain is an important risk factor for low-back pain. Recently a passive exoskeleton (SPEXOR) has been developed to reduce loading on the low back. We aimed to assess the effect of this device on metabolic cost of repetitive lifting. To explain potential eff...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-019-04284-6
更新日期:2020-02-01 00:00:00
abstract::The maximal lactate steady state (MLSS) is defined as the highest blood lactate concentration that can be maintained over time without a continual blood lactate accumulation. The objective of the present study was to analyze the effects of pedal cadence (50 vs. 100 rev min(-1)) on MLSS and the exercise workload at MLS...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-0090-8
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:Voluntary breath-holding (BH) elicits several hemodynamic changes, but little is known about maximal static immersed-body BH. We hypothesized that the diving reflex would be strengthened with body immersion and would spare more oxygen than maximal dry static BH, resulting in a longer BH duration. METHODS:Eleve...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-013-2690-z
更新日期:2013-10-01 00:00:00
abstract::The aim of this study was to employ neuro-fuzzy logic and regression calculations to determine the accuracy of prediction of the power output ( P) of the maximal lactate steady-state (MLSS) on a cycle ergometer calculated from the results of incremental tests. A group of 17 male and 17 female sports students underwent...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-002-0702-5
更新日期:2002-12-01 00:00:00
abstract::The present study investigated the changes occurring in interstitial metabolite concentrations and blood flow in insulin-resistant human skeletal muscle during the post-exercise recovery period following a single 2-h bout of one-legged exercise. In addition, the effect of microdialysis perfusion with insulin or the in...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0753-3
更新日期:2008-07-01 00:00:00
abstract::The purpose of this study was to investigate the effects of resistance training on the morphological and functional properties of human lower limb muscles during 20 days of 6 degrees head-down-tilt bed rest. Nine men were randomly assigned to the resistance training group (BR-Tr, n = 5) or the non-training, control gr...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s004210050648
更新日期:2000-05-01 00:00:00
abstract::Sixteen male students exercised for 14 days (1 h/day) in the heat for heat acclimation (HA). During deacclimation (DA) one group exercised in the cold (EXG, n=8) for 60 min/day (morning) and was exposed to the cold for another hour (afternoon) for 14 days. The other group was exposed to the cold (EPG, n=8) for 1 h eac...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-0012-9
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:Cold injuries are more prevalent in individuals of African descent (AFD). Therefore, we investigated the effect of extremity cooling on skin blood flow (SkBF) and temperature (T sk) between ethnic groups. METHODS:Thirty males [10 Caucasian (CAU), 10 Asian (ASN), 10 AFD] undertook three tests in 30 °C air whils...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-014-2962-2
更新日期:2014-11-01 00:00:00
abstract::We have previously reported the unique regional responses of facial skin blood flow (SkBF) to oral application of the basic tastes without simultaneous systemic circulatory changes. In the present study, we determined whether a systemic circulatory challenge due to sympathetic activation induces regional differences i...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-012-2522-6
更新日期:2013-04-01 00:00:00
abstract::Nitric oxide (NO) is important for the pulmonary circulation response to acute and chronic hypoxia. We examined effects of endogenous nitric oxide synthase (NOS) inhibition on pulmonary vascular tone in response to hypoxia in Tibetan sheep dwelling at 3,000 m above sea level using a pressure chamber. Unanaesthetized m...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-004-1197-z
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:Contract-relax (CR) stretching increases range of motion (ROM) substantively, however its use in athletic environments is limited as the contractions performed in a highly stretched position require partner assistance, are often painful, and may induce muscle damage. Therefore, the acute effects of performing t...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-015-3320-8
更新日期:2016-03-01 00:00:00
abstract::Microdialysis presents the unique possibility to measure metabolite concentrations in human interstitial fluid. During exercise, the recovery of these metabolites should be precisely monitored since it is known to increase greatly with muscle blood flow. The loss of ethanol, perfused at low concentration, can be accur...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-004-1099-0
更新日期:2004-07-01 00:00:00
abstract::Although pacing-related research is widely reported, no studies have described the consistency of pacing strategies or their associated energetic contributions. This study aimed to investigate the consistency of pacing and energetic outlay by establishing the typical within and between trial variations during simulate...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-010-1818-7
更新日期:2011-08-01 00:00:00
abstract::The measurement of human muscle size is essential when assessing the effects of training, disuse and ageing. The considered 'gold standard' for cross-sectional area measurements of muscle size is magnetic resonance imaging (MRI). However, MRI is costly and often inaccessible. The aim of the present study was to test t...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-003-0961-9
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:The prevalence of lifestyle diseases has escalated, and effective exercise training programmes are warranted. This study tested the hypothesis that regular participation in small-sided team handball training could provide beneficial health effects on cardiovascular, skeletal, and muscular parameters in young ad...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-018-4034-5
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the effects of two different kinds of prior exercise protocols [continuous exercise (CE) versus intermittent repeated sprint (IRS)] on oxygen uptake (VO2) kinetics parameters during high-intensity running. METHODS:Thirteen male amateur futsal players (age 22.8 ± 6.1 years; ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-014-3000-0
更新日期:2015-01-01 00:00:00
abstract::The purposes of this study were to compare the acute cardiorespiratory responses and muscle oxygenation trends during incremental cycle exercise to exhaustion with those observed during 30 s and 45 s Wingate tests in healthy men and women, and to examine the relationships between selected variables among these tests. ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s004210000372
更新日期:2001-06-01 00:00:00
abstract::The bilateral deficit phenomenon, characterized by a reduction in the amount of force from a single limb during maximal bilateral actions, has been shown in various movement tasks, contraction types and different populations. However, bilateral deficit appears to be an inconsistent phenomenon, with high variability in...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
doi:10.1007/s00421-016-3458-z
更新日期:2016-12-01 00:00:00
abstract::Isometric maximum voluntary force (MVF) of the adductor pollicis and first dorsal interosseous muscles was measured in 11 pre- and 11 post-menopausal (Pre-M and Post-M) human subjects. The temperature of the hand varied in the range 18°-38°C by water immersion and skin temperature was recorded. MVF at each temperature...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-011-2061-6
更新日期:2012-03-01 00:00:00